AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
January 1, 2014 12:43 PM
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Autoimmunity in CLL - YouTube

This outstanding webcast of Lymphoma & Myeloma 2013, an International Congress on Hematologic Malignancies, includes experts presenting the current issues an...
Gilbert C FAURE's insight:

Youtube and CME

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Scooped by Gilbert C FAURE
January 1, 2014 4:15 AM
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Multiple Sclerosis Research: B cells act as antigen presenting cells

Multiple Sclerosis Research: B cells act as antigen presenting cells | AUTOIMMUNITY | Scoop.it
MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies. J Exp Med. 2013 Dec. [Epub ahead of print]. Whether B cells serve as antigen-presenting ...
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Rescooped by Gilbert C FAURE from Immunopathology & Immunotherapy
December 31, 2013 8:53 AM
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Liver Disease Diagnostics: Antibody-based Diagnosis of Autoimmune Liver Diseases

Liver Disease Diagnostics: Antibody-based Diagnosis of Autoimmune Liver Diseases | AUTOIMMUNITY | Scoop.it
Liver Disease Diagnostics: Antibody-Based Diagnosis of Autoimmune Liver Disease For the launch of our Liver-9-Line immunoblot test (to our press release “Liver Disease Diagnostics by Immunoblot” of May 16, 2011), I dug through a pile of literature...

Via Alfredo Corell
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Scooped by Gilbert C FAURE
December 30, 2013 2:27 AM
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Multiple Sclerosis Research: Predicting Autoimmunity after Alemtuzumab

Multiple Sclerosis Research: Predicting Autoimmunity after Alemtuzumab | AUTOIMMUNITY | Scoop.it
So you add blood which contains IL-21 that is bound to the capture antibody and then you add the detect antibody that can now bind to the captured IL-21 and the more IL-21 in the blood the more that is captured the more ...
Gilbert C FAURE's insight:

elisa dependant.

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Scooped by Gilbert C FAURE
December 28, 2013 3:41 PM
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Bone marrow mesenchymal stem cells isolated from multiple sclerosis patients have decreased suppressive function

Bone marrow mesenchymal stem cells isolated from multiple sclerosis patients have decreased suppressive function | AUTOIMMUNITY | Scoop.it
Multiple sclerosis (MS), an inflammatory autoimmune disease affecting more than one million people worldwide, is caused by an immune reaction to myelin proteins, the proteins that help form the...
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Scooped by Gilbert C FAURE
December 28, 2013 1:46 PM
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Common disorders: It's not the genes themselves, but how they are controlled - Science Daily (press release)

Common disorders: It's not the genes themselves, but how they are controlled - Science Daily (press release) | AUTOIMMUNITY | Scoop.it
Common disorders: It's not the genes themselves, but how they are controlled Science Daily (press release) New research from Case Western Reserve University School of Medicine to appear in the journal Genome Research finds that six common diseases...
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Scooped by Gilbert C FAURE
December 27, 2013 5:57 AM
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Autoimmunity

Pathology, Diagnosis and Therapy

Gilbert C FAURE's insight:

Autoimmunity is indeed one of the biggest challenge of Immunology!

Understanding the mechanisms of this physiological immune phenomenon inducing such a diverse array of diseases, joint and muscular, digestive, endocrinological, neurological, cutaneous..

 

Among covered diseases

Lupus (>550 posts)

https://www.scoop.it/topic/autoimmunity?q=lupus

Scleroderma

https://www.scoop.it/topic/autoimmunity?q=scleroderma

Polymyositis

Sjögren's (>150)

https://www.scoop.it/topic/autoimmunity?q=sjogren

 

 

Diabetes (>400 posts)

https://www.scoop.it/topic/autoimmunity?q=diabetes

Mutiple sclerosis (>100 posts)

https://www.scoop.it/topic/autoimmunity?q=multiple+sclerosis

Thyroid disorders

https://www.scoop.it/topic/autoimmunity?q=thyroid

 

Improving the molecular and cellular tools in use for a few decades for diagnosis and follow-up of patients, perhaps screening in the future

Autoantibodies

https://www.scoop.it/topic/autoimmunity?q=autoantibody

 

Mastering the molecular and cellular mechanisms to treat patients.

Tregs

https://www.scoop.it/topic/autoimmunity?q=tregs

 

You can also find relevant informations on some other topics curated  here such as

Rheumatology

http://www.scoop.it/t/rheumatology-rhumatologie

Immunology and biotherapies

http://www.scoop.it/t/immunology-and-biotherapies

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Scooped by Gilbert C FAURE
December 25, 2013 2:15 PM
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Management of disease modifying treatments in neurological autoimmune diseases of the central nervous system - Salmen - Clinical & Experimental Immunology - Wiley Online Library

Management of disease modifying treatments in neurological autoimmune diseases of the central nervous system - Salmen - Clinical & Experimental Immunology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Management modifying treatments in neurological autoimmune diseases of the CNS  Clinical & Experimental Immunology http://t.co/38rQfeTPjI
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Scooped by Gilbert C FAURE
December 24, 2013 4:45 PM
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NK Cell Trafficking in Health and Autoimmunity:A Comprehensive Review - Online First - Springer

NK Cell Trafficking in Health and Autoimmunity:A Comprehensive Review - Online First - Springer | AUTOIMMUNITY | Scoop.it
“@Aller_MD: NK Cell Trafficking in Health and Autoimmunity:A Comprehensive Review. http://t.co/5VSHpLYi9j”;
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Scooped by Gilbert C FAURE
December 24, 2013 4:42 PM
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Molecular mitigation: Deleting microRNA-155 reduces autoimmune response - Medical Xpress

Molecular mitigation: Deleting microRNA-155 reduces autoimmune response - Medical Xpress | AUTOIMMUNITY | Scoop.it
Molecular mitigation: Deleting microRNA-155 reduces autoimmune response Medical Xpress In such cases, the antibodies target cells and tissues of our own bodies, leading to autoimmunity and a resulting autoimmune disease, examples of which include...
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Scooped by Gilbert C FAURE
December 24, 2013 2:12 AM
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Prevalence of anti-N-methyl-d-aspartate (NMDA) a... [Psychol Med. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
December 24, 2013 2:07 AM
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Newly recognized autoantibody found in blood sera years before RA diagnosis : Rheumatology News

Newly recognized autoantibody found in blood sera years before RA diagnosis : Rheumatology News | AUTOIMMUNITY | Scoop.it
Anti-carbamylated protein antibodies, a recently identified autoantibody system against carbamylated proteins, can be detected years before symptoms develop in rheumatoid arthritis, according to a retrospective study.
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Scooped by Gilbert C FAURE
December 21, 2013 2:22 PM
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Management of disease modifying treatments in neurological autoimmune diseases of the central nervous system - Salmen - Clinical & Experimental Immunology - Wiley Online Library

Management of disease modifying treatments in neurological autoimmune diseases of the central nervous system - Salmen - Clinical & Experimental Immunology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Immunology: Management of disease modifying treatments in neurological autoimmune diseases of the central nervous ... http://t.co/z0kvs3CmTY
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Scooped by Gilbert C FAURE
January 1, 2014 11:14 AM
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CD4+ T Cell Autoimmunity to Hypocretin/Orexin and Cross-Reactivity to a 2009 H1N1 Influenza A Epitope in Narcolepsy

CD4+ T Cell Autoimmunity to Hypocretin/Orexin and Cross-Reactivity to a 2009 #H1N1 Influenza A Epitope in Narcolepsy. http://t.co/5wVybCldPC
Gilbert C FAURE's insight:

link to the paper on narcolepsy

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Scooped by Gilbert C FAURE
January 1, 2014 4:15 AM
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The implication of vitamin D and au... [Clin Rev Allergy Immunol. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
December 30, 2013 3:58 PM
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Another CNS phenotype of anti-... [J Neurol Neurosurg Psychiatry. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
December 29, 2013 2:56 PM
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Using the Immune System to Fight Lupus - dailyRx

Using the Immune System to Fight Lupus - dailyRx | AUTOIMMUNITY | Scoop.it
Using the Immune System to Fight Lupus
dailyRx
A new review of biologic agents developed for lupus and other autoimmune diseases has highlighted several new therapies that have shown some promise for use in SLE.
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Scooped by Gilbert C FAURE
December 28, 2013 1:47 PM
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10 Questions: Robert Spiera, MD - MedPage Today

10 Questions: Robert Spiera, MD - MedPage Today | AUTOIMMUNITY | Scoop.it
MedPage Today
10 Questions: Robert Spiera, MD
MedPage Today
Spiera is director of the Scleroderma and Vasculitis Center at the Hospital for Special Surgery and professor of clinical medicine at Weill Cornell Medical College in New York City.
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Scooped by Gilbert C FAURE
December 28, 2013 1:43 PM
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Do inhibitory immune receptors play a role in the etiology of autoimmune disease?

“@ImmunologyNews: nice review re role of immune inhibitory receptors in autoimmunity
http://t.co/sYcBnssy1M”;
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Scooped by Gilbert C FAURE
December 27, 2013 5:55 AM
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Frontiers | Long-Lived Plasma Cells in Autoimmunity: Lessons from B-Cell Depleting Therapy | Frontiers in B Cell Biology

A large number of autoimmune diseases are treated with rituximab, an antibody against CD20 that depletes most of the B cells in the organism.
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Scooped by Gilbert C FAURE
December 25, 2013 2:04 PM
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Another Autoantibody System May Play Role in Rheumatoid Arthritis

Another Autoantibody System May Play Role in Rheumatoid Arthritis | AUTOIMMUNITY | Scoop.it
Researchers believe they have identified another autoantibody system, other than anti-CCP and IgM-RF (rheumatoid factor) which may contribute to the development (Researchers believe they have identified another autoantibody system, other than...
Gilbert C FAURE's insight:

for other informations related to rheumatoid arthritis in this topic

http://www.scoop.it/t/autoimmunity?q=rheumatoid

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Scooped by Gilbert C FAURE
December 24, 2013 4:43 PM
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International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies -- Agmon-Levin et al. 73 (1): 17 -- Annals of the Rheumatic Diseases

25 new international guidelines on ANA & autoantibody testing. These are not screening tests and need not be repeated http://t.co/McJm1iAes9
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Scooped by Gilbert C FAURE
December 24, 2013 2:16 AM
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Multiple Sclerosis Research: Bacterial Toxins a cause of MS?

Multiple Sclerosis Research: Bacterial Toxins a cause of MS? | AUTOIMMUNITY | Scoop.it
... nasopharygeal flora, the leptomeninges and CNS parenchyma acquire the characteristics of a persistently stimulated lymphoid organ. Using an extensive panel of bacterial antibodies, tissues from exceptionally early cases, ...
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Scooped by Gilbert C FAURE
December 24, 2013 2:08 AM
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Frontiers | Lymphopenia-induced proliferation in Aire-deficient mice helps to explain their autoimmunity and differences from human patients | Frontiers in T Cell Biology

Studies on autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) and its mouse model – both caused by mutant AIRE – have greatly advanced the under-standing of thymic processes that generate a self-tolerant T-cell repertoire.
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Scooped by Gilbert C FAURE
December 22, 2013 1:49 PM
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Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study : The Lancet Neurology

Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study. By - Nuria Gresa-Arribas PhD, Maarten J Titulaer MD, Abiguei Torrents BS, Esther Aguilar...
Gilbert C FAURE's insight:

the paper itself

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