AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
April 1, 2014 5:55 AM
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MLabs :: Clinical Immunology

MLabs :: Clinical Immunology | AUTOIMMUNITY | Scoop.it
The Clinical Immunology Laboratory offers a wide variety of autoantibody tests and protein electrophoresis  http://t.co/sBwyI0bR2H
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Scooped by Gilbert C FAURE
March 22, 2014 2:46 PM
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Highlighted article - February - Clinical Immunology - Elsevier

Highlighted article - February - Clinical Immunology - Elsevier | AUTOIMMUNITY | Scoop.it
SLAP deficiency decreases dsDNA autoantibody production (Lisa K. Peterson)

Lisa K. Peterson, Luke F. Pennington, Laura A. Shaw, Meredith Brown...
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Scooped by Gilbert C FAURE
March 13, 2014 11:26 PM
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Spatial Environmental Modeling of Autoantibody ... - MDPI.com

Spatial Environmental Modeling of Autoantibody ... - MDPI.com | AUTOIMMUNITY | Scoop.it
In this study of autoimmunity among a population of Gullah African Americans in South Carolina, the links between environmental exposures and autoimmunity (presence of antinuclear antibodies (ANA)) have been assessed.
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Scooped by Gilbert C FAURE
March 7, 2014 3:19 AM
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Genes and Immunity - MHC associations with clinical and autoantibody manifestations in European SLE

Genes and Immunity - MHC associations with clinical and autoantibody manifestations in European SLE | AUTOIMMUNITY | Scoop.it
Genes and Immunity is a journal dedicated to functional genetics of the immune response. Emphasizing studies that demonstrate genetic, genomic or functional variation in the immune system, Genes and Immunity assists our understanding of how the basic control over the immune system varies between individuals both in health and disease.
Gilbert C FAURE's insight:

They found evidence of associations independent of MHC class II variants in the anti-Ro subset alone. Conditional analyses showed that anti-Ro and anti-La subsets are independently associated with HLA-DRB1*0301, and that the HLA-DRB1*03:01 association with SLE is largely but not completely driven by the association of this allele with these sub-phenotypes. Our results provide strong evidence for a multilevel risk model for HLA-DRB1*03:01 in SLE, where the association with anti-Ro and anti-La antibody-positive SLE is much stronger than SLE without these autoantibodies.

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Scooped by Gilbert C FAURE
March 2, 2014 6:40 AM
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Granulocyte-dependent Autoantibody-induced Skin Blistering

To watch this video on jove.com, click here: http://www.jove.com/video/4250?utm_source=youtube In the animal model described in our present work, purified Ig...
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Suggested by Société Francaise d'Immunologie
February 22, 2014 1:46 PM
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IDO2 Is a Critical Mediator of Autoantibody Production and Inflammatory Pathogenesis in a Mouse Model of Autoimmune Arthritis [AUTOIMMUNITY]

IDO2 Is a Critical Mediator of Autoantibody Production and Inflammatory Pathogenesis in a Mouse Model of Autoimmune Arthritis [AUTOIMMUNITY] | AUTOIMMUNITY | Scoop.it
Rheumatoid arthritis and other autoimmune disorders are associated with altered activity of the immunomodulatory enzyme IDO. However, the precise contributions of IDO function to autoimmunity remain unclear.
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Scooped by Gilbert C FAURE
February 14, 2014 6:00 AM
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Anticytokine Autoantibody–Associated Immunodeficiency - Annual Review of Immunology, 32(1):

Anticytokine Autoantibody–Associated Immunodeficiency - Annual Review of Immunology, 32(1): | AUTOIMMUNITY | Scoop.it
Anticytokine Autoantibody-Associated Immunodeficiency http://t.co/Ph55kX8XR0
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Scooped by Gilbert C FAURE
February 13, 2014 5:44 AM
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Evaluation of Clinical Interest of Anti-Aquaporin-4 Autoantibody ...

Journal of Immunology Research (formerly titled Clinical and Developmental Immunology) is a peer-reviewed, open access journal that publishes original research articles, review articles, and clinical studies in all areas ...
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Scooped by Gilbert C FAURE
February 5, 2014 9:32 AM
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WO2014018903A1 AUTOANTIBODY PROFILES IN EARLY DETECTION AND DIAGNOSIS OF CANCER

WO2014018903A1 AUTOANTIBODY PROFILES IN EARLY DETECTION AND DIAGNOSIS OF CANCER | AUTOIMMUNITY | Scoop.it
WIPO patent: The present invention provides methods, compositions and kits for the detection of cancer diagnostic biomarkers, for the diagnosis of cancer, for the identification of a subject at risk for developing cancer, and for the generation of...
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Scooped by Gilbert C FAURE
January 25, 2014 7:36 AM
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Autoantibody Testing on ADVANCE for Administrators of the Laboratory

Autoantibody Testing on ADVANCE for Administrators of the Laboratory | AUTOIMMUNITY | Scoop.it
Trending overuse of these assays makes patients sick and costs rise (#Autoantibody Testing:Trending overuse of assays makes patients sick and costs rise http://t.co/x5fscnSq5x)...
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Scooped by Gilbert C FAURE
January 9, 2014 2:08 PM
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Islet autoantibody seroconversion precedes type 1 diabetes | T1DF ...

Islet autoantibody seroconversion precedes type 1 diabetes | T1DF ... | AUTOIMMUNITY | Scoop.it
Link to original article Islet autoantibody seroconversion precedes type 1 diabetes By: MARY ANN MOON, Clinical Endocrinology News Digital Network In children at genetic risk for type 1 diabetes, the development of multiple ...
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Scooped by Gilbert C FAURE
December 27, 2013 5:57 AM
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Autoimmunity

Pathology, Diagnosis and Therapy

Gilbert C FAURE's insight:

Autoimmunity is indeed one of the biggest challenge of Immunology!

Understanding the mechanisms of this physiological immune phenomenon inducing such a diverse array of diseases, joint and muscular, digestive, endocrinological, neurological, cutaneous..

 

Among covered diseases

Lupus (>550 posts)

https://www.scoop.it/topic/autoimmunity?q=lupus

Scleroderma

https://www.scoop.it/topic/autoimmunity?q=scleroderma

Polymyositis

Sjögren's (>150)

https://www.scoop.it/topic/autoimmunity?q=sjogren

 

 

Diabetes (>400 posts)

https://www.scoop.it/topic/autoimmunity?q=diabetes

Mutiple sclerosis (>100 posts)

https://www.scoop.it/topic/autoimmunity?q=multiple+sclerosis

Thyroid disorders

https://www.scoop.it/topic/autoimmunity?q=thyroid

 

Improving the molecular and cellular tools in use for a few decades for diagnosis and follow-up of patients, perhaps screening in the future

Autoantibodies

https://www.scoop.it/topic/autoimmunity?q=autoantibody

 

Mastering the molecular and cellular mechanisms to treat patients.

Tregs

https://www.scoop.it/topic/autoimmunity?q=tregs

 

You can also find relevant informations on some other topics curated  here such as

Rheumatology

http://www.scoop.it/t/rheumatology-rhumatologie

Immunology and biotherapies

http://www.scoop.it/t/immunology-and-biotherapies

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Scooped by Gilbert C FAURE
December 24, 2013 4:43 PM
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International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies -- Agmon-Levin et al. 73 (1): 17 -- Annals of the Rheumatic Diseases

25 new international guidelines on ANA & autoantibody testing. These are not screening tests and need not be repeated http://t.co/McJm1iAes9
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Scooped by Gilbert C FAURE
March 26, 2014 5:14 PM
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Human Traumatic Brain Injury Induces Autoantibody Response against Glial Fibrillary Acidic Protein and Its Breakdown Products

Human Traumatic Brain Injury Induces Autoantibody Response against Glial Fibrillary Acidic Protein and Its Breakdown Products | AUTOIMMUNITY | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Scooped by Gilbert C FAURE
March 16, 2014 3:02 PM
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International Autoantibody Standardizing (IAS) Workshop

International Autoantibody Standardizing (IAS) Workshop | AUTOIMMUNITY | Scoop.it
Workshop International Autoantibody Standardizing (IAS) http://t.co/YwTttf2o74
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Scooped by Gilbert C FAURE
March 9, 2014 12:43 AM
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Autoantibody biomarkers in childhood-acquired demyelinating syndromes: results from a national surveillance cohort -- Hacohen et al. 85 (4): 456 -- Journal of Neurology, Neurosurgery & Psychiatry

Autoantibody biomarkers in childhood-acquired demyelinating syndromes: results from a national surveillance cohort http://t.co/wpWirtihmH
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Scooped by Gilbert C FAURE
March 3, 2014 1:51 PM
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BMC Medicine | Full text | Automated tests of ANA immunofluorescence as throughput autoantibody detection technology: strengths and limitations

Anti-nuclear antibody (ANA) assay is a screening test used for almost all autoimmune rheumatic diseases, and in a number of these cases, it is a diagnostic/classification parameter.
Gilbert C FAURE's insight:

Current evidence from preliminary study results indicates that there is good correlation between manual and automated interpretation of ANA IIF assays, at least in the ability to discriminate between positive and negative results and in recognizing the main IIF patterns. Such systems will therefore speed up routine performance of these tests and help to harmonize interpretation of the results across laboratories. However, there is a need to have their clinical diagnostic power validated by clinical studies, in addition to the analytical studies that have already been published. In addition, these new systems could be further improved if they were better able to recognize mixed fluorescent or less common fluorescent patterns.

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Scooped by Gilbert C FAURE
March 2, 2014 6:36 AM
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Autoantibody Titers Predict Disease Activity in Autoimmune Hepatitis

Persistent high titers of ASMA and F-actin were associated with biochemical and histologic disease activity in a longitudinal study.
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Scooped by Gilbert C FAURE
February 21, 2014 1:06 PM
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Association of autoantibody specificity and... [J Thromb Haemost. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
February 13, 2014 5:46 AM
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Evaluation of a Multiplex ELISA for Autoantibody Profiling in Patients ...

The performance of immunoassays for the detection of autoantibodies is of critical importance in the diagnosis and assessment of patients with autoimmune connective tissue diseases (ACTD). Our objective was to compare ...
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Scooped by Gilbert C FAURE
February 6, 2014 4:10 AM
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Evaluation of a Multiplex ELISA for Autoantibody Profiling in Patients with Autoimmune Connective Tissue Diseases | Allergy, Asthma and Immunology

Evaluation of a Multiplex ELISA for Autoantibody Profiling in Patients with Autoimmune Connective Tissue Diseases | Allergy, Asthma and Immunology | AUTOIMMUNITY | Scoop.it
Evaluation of a Multiplex ELISA for Autoantibody Profiling in Patients with Autoimmune Connective Tis... http://t.co/eMUNQCHGkO
Gilbert C FAURE's insight:

autoantibody testing remains a challenge and requires different types of techniques (IF, Elisa...)

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Scooped by Gilbert C FAURE
February 4, 2014 8:54 AM
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つくばリポジトリ (Tulips-R): Involvement of Fcα/μR (CD351) in autoantibody production

Involvement of Fcα/μR (CD351) in autoantibody production http://t.co/hxokOql4k0
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Scooped by Gilbert C FAURE
January 17, 2014 7:33 AM
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Autoantibody-Mediated Bone Loss. [Curr Osteoporos Rep. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:

bone and autoimmunity, a new kid on the block

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Scooped by Gilbert C FAURE
January 3, 2014 3:00 PM
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Standardization of autoantibody testing: a paradigm for serology in rheumatic diseases : Nature Reviews Rheumatology : Nature Publishing Group

RT @westr: Standardization of autoantibody testing: a paradigm for serology in rheumatic diseases. NRR http://t.co/PxPQZVUvQR #pm101 #rheum…
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Scooped by Gilbert C FAURE
December 25, 2013 2:04 PM
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Another Autoantibody System May Play Role in Rheumatoid Arthritis

Another Autoantibody System May Play Role in Rheumatoid Arthritis | AUTOIMMUNITY | Scoop.it
Researchers believe they have identified another autoantibody system, other than anti-CCP and IgM-RF (rheumatoid factor) which may contribute to the development (Researchers believe they have identified another autoantibody system, other than...
Gilbert C FAURE's insight:

for other informations related to rheumatoid arthritis in this topic

http://www.scoop.it/t/autoimmunity?q=rheumatoid

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