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This chapter 17 in the book "Food Security for African Smallholder Farmers" was selected to highlight the importance of CA adoption to help mitigate climate change in Southern Africa. Crop yields in the smallholder sector have continued to decline, and farmers whose livelihoods rely on agriculture are poor and food-insecure. This chapter provides a review on how the farmers can build resilience to climate change through adoption of conservation agriculture (CA). Conservation agriculture has several positive attributes, which enable crop productivity in semi-arid regions of southern Africa. Among other advantages, CA maintains or improves soil structure; reduces soil exposure to water and wind erosion; increases water infiltration and reduces loss through evaporation. Minimum soil disturbance slows organic matter breakdown and mineralization resulting in organic carbon build-up.