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Scooped by
Gilbert C FAURE
December 2, 2013 9:13 AM
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A topic dedicated to allergy
ouvert dans le contexte du DESC d'Immunologie clinique et allergologie en France  opened for 10 years, > 2800 Highly selected scoops in an evolving and controversial field  >14.4 K Views by > 4.4 K viewers Â
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Scooped by
Gilbert C FAURE
October 2, 2:39 AM
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âšOne of the most appreciated/liked articles in the social media of Allergy published in 2025:
Hypereosinophilia and Hypereosinophilic Syndromes: First Findings From a Nationwide Multicenter Cohort. Corresponding author: Guillaume LefĂšvre
Read the article here: doi.org/10.1111/all.16463
The COHESion study is the first prospective large-scale multicenter study dedicated to all hypereosinophilia/hypereosinophilic syndrome (HE/HES) subtypes. The final diagnoses were idiopathic HES (HES-I, 47%), HE/HES-reactive (16%), HE-uncertain significance (15%), HE/HES-neoplastic (7%), HE/HES-lymphocytic (6%), IgG4-related disease (2%), and antineutrophil cytoplasmic antibody-negative eosinophilic granulomatosis with polyangiitis (EGPA) (7%). Considering all HES subtypes, the most frequent symptoms were cutaneous, respiratory and digestive symptoms (42%, 30% and 25%, respectively) followed by cardiac manifestations, vascular manifestations and ear, nose, throat (ENT) symptoms (12%, 9% and 7%, respectively).
#Allergy_journal Read more articles published in #Allergy on clinical immunology here: https://lnkd.in/ex3Y69tY
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Scooped by
Gilbert C FAURE
October 1, 10:11 AM
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The tick-borne allergy to animal products is on the move north and west from the Mid-Atlantic and Southern states.
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Scooped by
Gilbert C FAURE
September 15, 3:57 AM
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https://lnkd.in/eF54n794 Intelligence artificielle et allergologie : oĂč en est on? (Pour les Parisiens je fais demain soir une intervention sur le sujet avec Paris-Allergie merci Ă Marmouz Farid Christian MARTENS
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Scooped by
Gilbert C FAURE
August 28, 2:36 PM
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#allergies Le réseau d'allergovigilance souhaite rendre obligatoire, en Europe, la déclaration de quatre allergÚnes alimentaires émergents supplémentaires, sur la base d'une étude rapportée dans APMnews en décembre 2023, publiée dans Clinical & Experimental Allergy
https://lnkd.in/erY6v8_M?
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Scooped by
Gilbert C FAURE
August 9, 1:37 PM
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Scooped by
Gilbert C FAURE
August 7, 3:35 AM
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"A blog about allergy, asthma & immunology"
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Scooped by
Gilbert C FAURE
July 30, 4:30 AM
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Asthma and chronic rhinosinusitis (CRS) are common chronic inflammatory diseases of the respiratory tract that have increased in prevalence over the past five decades. The clinical relationship between asthma and CRS has been well recognized, suggesting a common pathogenesis between these diseases. Both diseases are driven by complex airway epithelial cell and immune cell interactions that occur in response to environmental triggers such as allergens, microorganisms and irritants. Advances, including a growing understanding of the biology of the cells involved in the disease, the application of multiomics technologies and the performance of large-scale clinical studies, have led to a better understanding of the pathophysiology and heterogeneity of asthma and CRS. This research has promoted the concept that these diseases consist of several endotypes, in which airway epithelial cells, innate lymphoid cells, T cells, B cells, granulocytes and their mediators are distinctly involved in the immunopathology. Identification of the disease heterogeneity and immunological markers has also greatly improved the protocols for biologic therapies and the clinical outcomes in certain subsets of patients. However, many clinical and research questions remain. In this Review, we discuss recent advances in characterizing the immunological mechanisms of asthma and CRS, with a focus on the main cell types and molecules involved in these diseases. In this Review, Kato and Kita discuss the complex interactions between airway epithelial cells and immune cells that contribute to the development of asthma and chronic rhinosinusitis. They highlight recent advances in understanding the clinical heterogeneity of these diseases and explain the progress that has been made in developing new therapies.
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Scooped by
Gilbert C FAURE
July 19, 8:06 AM
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Scooped by
Gilbert C FAURE
July 8, 8:34 AM
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8th July is World Allergy Day. This article in Times Of India mentioned about our old study: Allergic diseases have significant impact on the quality-of-life, social life, and economy. Inadequate knowledge about allergic testing further add on to the burden of the disease. Reposting this for awareness about harmonisation of allergens testing. The clinical suspicion of allergic sensitization can be confirmed by demonstrating the presence of allergen specific immunoglobulin-E (IgE) antibodies in vivo (skin prick test) or in vitro methods (Blood tests: FEIA, ELISA, CRD etc). There is a lack of well-defined protocols and guidelines for the diagnosis of respiratory allergy testing in India. Therefore, the evidence-based guidelines is the need of the hour.
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Scooped by
Gilbert C FAURE
June 23, 6:49 AM
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Scooped by
Gilbert C FAURE
May 28, 10:55 AM
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#Allergie #BilanBiologique
Avec 33 % dâallergiques pour un peu plus de 1 000 allergologues en France, les dĂ©lais de rendez-vous sâallongent. Les MG doivent alors assurer la prise en charge en attendant le bilan complet chez le spĂ©cialiste (tests cutanĂ©s, de provocation oraleâŠ). Faisons le point sur les bonnes pratiques en termes de bilan biologique, dâaprĂšs les recos de la SociĂ©tĂ© française dâallergologie.
đđ https://lnkd.in/gfcHxzaB
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Scooped by
Gilbert C FAURE
May 16, 2:00 PM
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Allergies : les diffĂ©rences dâincidences entre la ville et la campagne expliquĂ©es
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Scooped by
Gilbert C FAURE
October 2, 2:42 AM
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âšâšâš Nous sommes trĂšs heureux dâannoncer la publication des rĂ©sultats de #AllergenChipChallenge dans la prestigieuse revue Journal of Allergy and Clinical Immunology https://lnkd.in/e_Mn4c73
Ce projet est le fruit dâun travail collectif remarquable, qui a rassemblĂ© cliniciens, biologistes, data scientists et chercheurs autour dâun objectif commun : mieux comprendre et interprĂ©ter les donnĂ©es issues des puces Ă allergĂšnes et de gĂ©nĂ©rer par #MachineLearning un #algorithme de prĂ©diction des #allergies Ă partir d'un profil d'IgE et de donnĂ©es cliniques.
La base de données et l'algorithme sont en libre accÚs au bénéfice de la recherche et des patients allergiques.
Un grand merci đ Ă Joana Vitte et Pascal Demoly pour avoir initiĂ© ce passionnant projet, la SociĂ©tĂ© Française d'Allergologie - SFA, AllergoBioNet, Health Data Hub et Bpifrance pour leur soutien dĂ©terminant, ainsi quâĂ toutes celles et ceux qui ont contribuĂ© Ă rendre cette aventure possible Guillaume Martinroche Amir Guemari Pol AndrĂ© APOIL Isabella Annesi-Maesano Eric Fromentin @Laurent Guilleminault Davide Caimmi Caroline Klingebiel @CĂ©line Beauvillain Alain Didier Jeremy Corriger Lauriane Armand Agathe Delaune Trustii.io Naama BAK CHU de Bordeaux.
âĄïž Ces avancĂ©es montrent la puissance de la collaboration et de lâouverture des donnĂ©es pour faire progresser la recherche en allergologie et au-delĂ . Le projet continue.
#OpenData #Database #Allergie #Allergologie #Allergy #Immunologie #Recherche #IA #MachineLearning #SFA #GTESIA
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Scooped by
Gilbert C FAURE
October 1, 10:12 AM
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The report updates the AAPâs 2010 guidance and emphasizes a proactive role for pediatricians in collaborating to manage student food allergies.
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Scooped by
Gilbert C FAURE
September 27, 5:56 AM
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âĄïž Le CNPA a finalisĂ© lâactualisation du RĂ©fĂ©rentiel MĂ©tier dâAllergologue. Ce travail initiĂ© sous la prĂ©sidence du Dr SĂ©bastien LEFEVRE prĂ©cise les compĂ©tences et missions de lâallergologue, sa place dans le parcours de soins du patient, ses liens avec les autres spĂ©cialitĂ©s et professionnels de santĂ©.
â
LâAllergologie se structure pour rĂ©pondre aux enjeux actuels, en particulier lâaugmentation de la prĂ©valence et de la sĂ©vĂ©ritĂ© des allergies. Ce document tĂ©moigne de lâexpertise mĂ©dicale et de lâengagement de notre spĂ©cialitĂ©.
Merci à toute l'équipe de rédacteurs coordonnée par LEZMI Guillaume et celle des relecteurs coordonnée par Edouard SÚve.
Bonne lecture !
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Scooped by
Gilbert C FAURE
August 31, 9:17 AM
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Glad to have contributed to this international đđđeffort to update the #Classification and #Diagnosis of #NSAIDs đ #Hypersensitivity Available: https://lnkd.in/gWQtqFAN
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Suggested by
LIGHTING
August 11, 4:46 AM
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Aujourdâhui, je vais vous parler de la rhinite allergique.
« Non mais arrĂȘte, il a juste un rhume ! ». Câest vrai que cela peut paraĂźtre banal, sans intĂ©rĂȘt, mĂȘme les mĂ©decins ont tendance Ă banaliser le « rhume ». Un nez qui coule, un nez bouchĂ©, des Ă©ternuements ? Rien de bien mĂ©chantâŠĂ§a encombre les consultations des mĂ©decins traitants qui ne savent souvent pas quoi en faire⊠Et pourtantâŠnombre de ces « rhumes » sont en rĂ©alitĂ© des rhinites allergiques et les nĂ©gliger ce nâest pas vous (âŠ) , actualitĂ©s des allergies : publications scientifiques lues et analysĂ©es pour vous, annonce et compte-rendus d'Ă©vĂ©nements sur les allergies.
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Scooped by
Gilbert C FAURE
August 8, 10:03 AM
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Scooped by
Gilbert C FAURE
August 1, 3:34 AM
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Nous avons uni notre expertise Ă celle de la SFAR pour co-construire un rĂ©fĂ©rentiel commun dĂ©diĂ© au diagnostic et Ă la prise en charge des rĂ©actions dâhypersensibilitĂ© immĂ©diate (HSI) en contexte pĂ©riopĂ©ratoire.
Découvrez quelques messages clés ci-dessous ou accédez à la ressource ici : https://lnkd.in/eKmfa9sj
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Scooped by
Gilbert C FAURE
July 28, 9:48 AM
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Have you already thought about how #terminology can influence #practice and #epidemiology? Here is a publication in #JAHD âŁïžas a good example #OccupationalHypersensitivity #HypersensitivityPneumonitis đŠđŠââŹ
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Scooped by
Gilbert C FAURE
July 15, 10:42 AM
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đš La T2A (Tarification Ă lâactivitĂ©) a profondĂ©ment transformĂ© notre systĂšme de santĂ©, mais pas toujours pour le mieux.
RĂ©sultat ? Des services dâurgence surchargĂ©s, souvent mobilisĂ©s pour des cas bĂ©nins ou des demandes sociales, faute dâoutils accessibles pour comprendre les symptĂŽmes en amont.
Chez BrightNTech.AI, nous pensons quâil est urgent dâoutiller la population gĂ©nĂ©rale avec des assistants Ă©thiques, capables de dĂ©coder les signaux du corps et de rĂ©orienter intelligemment vers le bon niveau de soins.
đĄ Câest le rĂŽle dâAllergIAâą, notre assistant IA spĂ©cialisĂ© en allergologie et immunologie :
â
Analyse interactive des symptĂŽmes â
Aide Ă diffĂ©rencier allergies, intolĂ©rances, et autres causes â
PrĂ©paration dâun rĂ©sumĂ© structurĂ© pour le pharmacien ou mĂ©decin â
Surtout : ne remplace jamais le diagnostic médical mais facilite un accÚs éclairé aux soins
đ Ne pas saturer les urgences pour une âbobologieâ nâest pas un jugement. Câest une urgence systĂ©mique. Il faut des ponts intelligents entre la technologie, le soin, et les citoyens.
đ DĂ©couvrez #AllergIAâą ici : https://lnkd.in/eXy5FGZ7
đ DĂ©veloppĂ© dans le respect strict du RGPD, de lâĂ©thique mĂ©dicale et des normes europĂ©ennes (MDR Class I - non diagnostic).
đ En savoir plus sur notre approche de conformitĂ© et de santĂ© publique : BrightNTech.AI
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Scooped by
Gilbert C FAURE
July 7, 5:48 AM
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đŹ Et si on arrĂȘtait de rĂ©duire les mastocytes Ă lâIgE ? Pendant des dĂ©cennies, la triade « mastocyte - IgE - allergie » a structurĂ© notre comprĂ©hension des rĂ©actions dâhypersensibilitĂ© immĂ©diate. Mais aujourdâhui, nous savons que cette vision est incomplĂšte.
đ Lâarticle-clĂ© paru en janvier 2025 (Int J Mol Sci. 26(3):927) montre que les mastocytes (MC) disposent dâun rĂ©pertoire de rĂ©cepteurs bien plus vaste que FcΔRI, et que leur activation peut suivre des voies non-IgE, dites "pseudoallergiques", via des rĂ©cepteurs comme MRGPRX2.
đ„ RĂ©sultat ? âĄïž Des rĂ©actions cliniques rapides, sans sensibilisation prĂ©alable ni IgE spĂ©cifique dĂ©tectable. âĄïž Une dĂ©granulation induite par des mĂ©dicaments (fluoroquinolones, vancomycine, morphine...), des neuropeptides (substance P), ou des stimuli physiques. âĄïž Une inflammation neurogĂšne amplifiĂ©e par lâinteraction Ă©troite entre MC et terminaisons nerveuses pĂ©riphĂ©riques.
đ§ Les implications dĂ©passent largement le champ allergologique classique : - Urticaire chronique, dermatite atopique, prurit rebelle - Syndrome dâactivation mastocytaire (MCAS) - RosacĂ©e, asthme non contrĂŽlĂ©, inflammation cĂ©rĂ©brale...
đĄComprendre MRGPRX2, câest Ă©largir notre cadre diagnostique et thĂ©rapeutique. đ De nouveaux traitements ciblent dĂ©jĂ cette voie : antagonistes de MRGPRX2, cannabinoĂŻdes non-psychoactifs (PEA, CBD), anticorps anti-Siglec-8...
đ§Ź Les mastocytes sont bien plus que des effecteurs allergiques. Ils sont au carrefour de lâimmunitĂ©, du systĂšme nerveux et des interfaces barriĂšre. Et si lâon actualisait nos rĂ©flexes cliniques ? Source : https://lnkd.in/etTeyKBh Dr Lucie WETCHOKO
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Scooped by
Gilbert C FAURE
June 12, 11:14 AM
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On behalf of the Allergy Diagnosis Working Group Of the French Society of Allergology (GTBA â SFA), Iâm proud to have contributed to the dissemination of the EAACI guidelines on the diagnosis of IgE-mediated Food Allergy within the French-speaking medical community: - French translation of the food allergy guidelines on diagnosis for a special issue of the French Allergy Journal (RFA) dedicated to Food Allergy: https://lnkd.in/dBAxRQXC - Plenary presentation at the French National Congress of Allergology (CFA 2025) in Paris with a focus on methodology based on the accuracy of diagnostic tests to understand the recommended diagnostic approach: https://lnkd.in/dGAEc7PK - Presentation at a workshop/controversy at the 30th National Congress of AMAFORCAL in Rabat, Morocco
Julien Goret, Joana Vitte, Alexandra Santos, MD PhD, Société Française d'Allergologie - SFA, European Academy of Allergy and Clinical Immunology - EAACI, @GTBA, Youness EL GUEDDARI, Elleni-Sofia Vaia
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Scooped by
Gilbert C FAURE
May 24, 2:13 AM
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đą One of the most appreciated/liked articles in the social media of Allergy published in 2024:
Open Access: Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration. Claudia Traidl-Hoffmann
Read the article here: Â doi.org/10.1111/all.16247
With over 170 references and 6 figures, this article summarizes the key points discussed during the Global Allergy Forum in Davos. During this event, scientific experts and stakeholders met to address the increasing prevalence of #atopicdermatitis (AD). Topics covered include: #epithelialbarrier maintenance and disturbances in atopic diseases; #environmental changes as a driving force of atopic diseases; immunological march along the course of AD; neuroimmunology, systemic inflammation and comorbidities; therapeutic, educational, and global economic aspects; future directions
Read more articles published in #Allergy on #asthma here: https://lnkd.in/dvHaYziZ
#Allergy_journal
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Scooped by
Gilbert C FAURE
May 11, 3:46 AM
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The best critical care literature, updated daily - CCR Journal Watch
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