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Allergy (and clinical immunology)
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Ressources et Actualités pour la spécialité Allergie
Curated by
Gilbert C FAURE
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Framework for Enhancing Urban Living Through Sustainable Plant Selection in Residential Green Spaces
Residential greening is a critical strategy for mitigating the negative impacts of urbanization on the environment, biodiversity, and human well-being. Proper plant species selection is essential for the success of residential greening projects, as it influences the ecological, aesthetic, and... 
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Gilbert C FAURE's insight:
IL-5, autres cytokines et anticorps monoclonaux
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Comparable production of IL-4 by both TFR and TFH cells. A helper role for TFR cells in food allergy was previously demonstrated with the use of TFR cell–deficient Foxp3CreBcl6fl/fl (Bcl6FC) mice (18).
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The prevalence of peanut allergy among children in Western countries has doubled in the past 10 years, and peanut allergy is becoming apparent in Africa and Asia. We evaluated strategies of peanut consumption and avoidance to determine which strategy ...
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Ce réseau a pour objet principal l'étude du contenu de l'air en particules biologiques pouvant avoir une incidence sur le risque allergique pour la population. C'est à dire l'étude du contenu de l'air en pollens et en moisissures ainsi que du recueil des données cliniques associées.
Le Réseau National de Surveillance Aérobiologique — RNSA
Image : Carte du Risque d'Allergie aux Pollens
Le retour d'un temps plus frais et humide apporte un peu de répit aux allergiques en freinant un peu les pollens d'ambroisie. Le risque d'allergie restera élevé pour les pollens d'ambroisie lors des periodes ensoleillées le long de la vallée du Rhône de la Nièvre à la Drôme. Dans les départements autour, le risque d'allergie sera faible à moyen.
Le risque d'allergie sera plus faible pour les autres herbacées en fin de floraison (graminées, plantain, armoise et orties (urticacées)). Via Bernadette Cassel
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The number of people in England with food allergies has more than doubled between 2008 and 2018, a new study reveals. The researchers, from Imperial College London, found that rates are highest among preschool children, with 4% having a “probable” food allergy.They also found that a third of those...
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Urticaria is an inflammatory skin disorder that affects up to 20% of the world population at some point during their life. It presents with wheals, angioedema or both due to activation and degranulation of skin mast cells and the release of histamine and other mediators. Most cases of urticaria are acute urticaria, which lasts ≤6 weeks and can be associated with infections or intake of drugs or foods. Chronic urticaria (CU) is either spontaneous or inducible, lasts >6 weeks and persists for >1 year in most patients. CU greatly affects patient quality of life, and is linked to psychiatric comorbidities and high healthcare costs. In contrast to chronic spontaneous urticaria (CSU), chronic inducible urticaria (CIndU) has definite and subtype-specific triggers that induce signs and symptoms. The pathogenesis of CSU consists of several interlinked events involving autoantibodies, complement and coagulation. The diagnosis of urticaria is clinical, but several tests can be performed to exclude differential diagnoses and identify underlying causes in CSU or triggers in CIndU. Current urticaria treatment aims at complete response, with a stepwise approach using second-generation H1 antihistamines, omalizumab and cyclosporine. Novel treatment approaches centre on targeting mediators, signalling pathways and receptors of mast cells and other immune cells. Further research should focus on defining disease endotypes and their biomarkers, identifying new treatment targets and developing improved therapies. Urticaria is an inflammatory skin disorder that presents with itchy wheals and/or angioedema mediated by skin mast cells and release of histamine and other mediators. This Primer by Kolkhir et al. summarizes the epidemiology, mechanisms, diagnosis and treatment of urticaria, and discusses patient quality of life and open research questions for this condition.
Gilbert C FAURE's insight:
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The inflammation process plays a crucial role in allergic respiratory diseases, such as asthma and allergic rhinitis. Although the pulmonary epithelium, the carpet of cells that forms the inner surface of the lungs, is recognized as a major player in the respiratory inflammation that causes these diseases, the underlying mechanisms are still poorly understood.
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An overactive population of natural killer cells in children with eczema may worsen skin damage and provoke allergic sensitivity or development of asthma.
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An injection given during some asthma and COPD attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment
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🔷 Le projet PrevHPV, mené depuis 2019, révèle une opinion favorable envers la vaccination HPV parmi les parents, mais des inégalités persistent, notamment…
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https://pubmed.ncbi.nlm.nih.gov/39560049/ Pediatr Allergy Immunol. 2024 Nov;35(11):e14276. doi: 10.1111/pai.14276.Hugh A Sampson, Stefania Arasi, Henry T Bahnson, Barbara Ballmer-Weber, Kirsten Beyer, Carsten Bindslev-Jensen, J Andrew Bird, Katarina Blumchen, Carla Davis, Motohiro Ebisawa, Anna Nowak-Wegrzyn,...
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"A blog about allergy, asthma & immunology"
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Schmitt, Duval, et al. show that TL1A is an epithelial cytokine that cooperates with IL-33 in the initiation of allergic airway inflammation. Similar to IL
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Summary. Basophils are the rarest leukocytes, but they have essential roles in protection against helminths, allergic disorders, autoimmune diseases, and some c
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