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Scooped by
Gilbert C FAURE
April 25, 2014 2:43 PM
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A Sweet Life LADA and GAD: Diagnosing Type 1.5 Diabetes A Sweet Life GAD is one of the earliest proteins to be targeted by antibodies, and so by testing for the presence of GAD antibodies, doctors can determine whether there is an autoimmune...
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Scooped by
Gilbert C FAURE
April 25, 2014 2:32 PM
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The operation of both central and peripheral tolerance ensures the prevention of autoimmune diseases. The maintenance of peripheral tolerance requires self-antigen presentation by professional antigen presenting cells (APCs). Dendritic cells (DCs) are considered as major APCs involved in this process. The current review discusses the role of DCs in autoimmune diseases, the various factors involved in the induction and maintenance of tolerogenic DC phenotype and pinpoints their therapeutic capacity as well as potential novel targets for future clinical studies.
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Rescooped by
Gilbert C FAURE
from NeuroImmunology
April 23, 2014 9:49 AM
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Scooped by
Gilbert C FAURE
April 21, 2014 1:54 PM
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by Jihong Yang, Zheng Li, Xiaohui Fan, Yiyu Cheng
A disease molecular signature is a set of biomolecular features that are prognostic of clinical phenotypes and indicative of underlying pathology.
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Suggested by
Société Francaise d'Immunologie
April 21, 2014 7:36 AM
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Immune complex (IC) deposition causes significant tissue injury associated with various autoimmune diseases such as vasculitis. In the cascade of inflammation, cell-to-cell and cell-to-matrix adhesion via adhesion molecules are essential.
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Suggested by
Société Francaise d'Immunologie
April 21, 2014 7:36 AM
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Increasing epidemiologic evidence supports a link between periodontitis and rheumatoid arthritis. The actual involvement of periodontitis in the pathogenesis of rheumatoid arthritis and the underlying mechanisms remain, however, poorly understood.
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Scooped by
Gilbert C FAURE
April 20, 2014 3:28 PM
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PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by
Gilbert C FAURE
April 19, 2014 5:54 AM
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FULL TEXT Abstract: Both the CTLA-4 pathway and regulatory T cells (Treg) are essential for the control of immune homeostasis. Their therapeutic relevance is...
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Scooped by
Gilbert C FAURE
April 17, 2014 4:46 AM
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PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by
Gilbert C FAURE
April 17, 2014 4:43 AM
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OBJECTIVE Diabetes-associated autoantibodies can be detected in adult-onset diabetes, even when initially non–insulin requiring, i.e., with latent autoimmune diabetes. We aimed to identify adult-onset autoimmune diabetes ...
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Scooped by
Gilbert C FAURE
April 15, 2014 3:19 PM
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Diabetes prevention scoring system improved accuracy of type 1 risk classification Healio “The findings indicate that a reliance upon dysglycemia as a demarcation of risk in autoantibody-positive populations could result in a less-than-optimal...
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Scooped by
Gilbert C FAURE
April 15, 2014 3:12 PM
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RT @NatRevRheumatol: New BSR & BHPR guidelines on management of adults with ANCA-associated #vasculitis http://t.co/fCL4QDFNV6 FREE
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Scooped by
Gilbert C FAURE
April 11, 2014 5:30 AM
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Atypical adenomatous hyperplasia (AAH) and squamous cell dysplasia (SCD) are associated with the development of malignant lesions in the lung. Accurate diagnosis of AAH and SCD could facilitate earlier clinical ...
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Scooped by
Gilbert C FAURE
April 25, 2014 2:40 PM
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Vitamin D effects on B cell function in autoimmunity: Vitamin D seems to be implicated in the pathophysiology ... http://t.co/vPZwkWTz8l
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Scooped by
Gilbert C FAURE
April 24, 2014 3:37 PM
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Republished: Antineutrophil cytoplasmic antibody-associated vasculitides: is it time to split up the group?: A... http://t.co/gi0e4KAF3u
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Scooped by
Gilbert C FAURE
April 21, 2014 2:07 PM
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AARDA Launches Innovative New Autoimmunity Curriculum for Elementary and ...
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Suggested by
Société Francaise d'Immunologie
April 21, 2014 7:36 AM
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Experimental autoimmune encephalomyelitis (EAE) is a valuable model for studying immunopathology in multiple sclerosis (MS) and for exploring the interface between autoimmune responses and CNS tissue that ultimately leads to lesion development.
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Suggested by
Société Francaise d'Immunologie
April 21, 2014 7:36 AM
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The mechanistic target of rapamycin (mTOR) is activated in CD4–CD8– double-negative (DN) T cells and its blockade is therapeutic in systemic lupus erythematosus (SLE) patients.
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Suggested by
Société Francaise d'Immunologie
April 21, 2014 7:36 AM
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Structural congenital heart disease (CHD) has not previously been linked to autoimmunity.
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Scooped by
Gilbert C FAURE
April 19, 2014 5:56 AM
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Scooped by
Gilbert C FAURE
April 17, 2014 1:28 PM
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Medscape Antineutrophil Cytoplasm Antibody-Associated Vasculitis Medscape Purpose of review The current standard therapy for antineutrophil cytoplasm antibody-associated vasculitis (AAV), high-dose glucocorticoid and cyclophosphamide followed by...
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Scooped by
Gilbert C FAURE
April 17, 2014 4:45 AM
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Algorithm differentiated celiac disease from non-celiac gluten sensitivity Healio The algorithm first posits that patients with negative celiac serologies (IgA trans-glutaminase antibody [IgA tTG] or IgA/IgG deaminated gliadan peptide antibody...
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Scooped by
Gilbert C FAURE
April 16, 2014 1:14 PM
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Immune System Genes Activated by Estrogen May Hold Clues to Lupus Origin
Newswise (press release)
The study on TLR8 was published in the March issue of Clinical Immunology.
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Scooped by
Gilbert C FAURE
April 15, 2014 3:19 PM
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Although current thinking has focused on genetic variation between individuals and environmental influences as underpinning susceptibility to both autoimmunity and cancer, an alternative view is th...
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Scooped by
Gilbert C FAURE
April 14, 2014 5:33 AM
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The Federation of Clinical Immunology Societies (FOCIS) exists to improve human health through immunology by fostering interdisciplinary approaches to both understand and treat immune-based diseases.
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