AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
May 10, 2014 9:42 AM
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Rheuminations: Drug-Induced Lupus, a Case Report - MedPage Today

Rheuminations: Drug-Induced Lupus, a Case Report - MedPage Today | AUTOIMMUNITY | Scoop.it
Rheuminations: Drug-Induced Lupus, a Case Report MedPage Today LIVERPOOL -- Much experience with safety and efficacy has been gained with biologic treatment for rheumatoid arthritis and other autoimmune diseases in the 16 years since infliximab...
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Scooped by Gilbert C FAURE
May 8, 2014 2:56 PM
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Arthritis in Idiopathic Inflammatory Myopathy: Clinical Features and Autoantibody Associations

Arthritis in Idiopathic Inflammatory Myopathy: Clinical Features and Autoantibody Associations from @jrheum http://t.co/mECfKDqanw
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Suggested by Société Francaise d'Immunologie
May 8, 2014 2:55 PM
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Opposing Impact of B Cell-Intrinsic TLR7 and TLR9 Signals on Autoantibody Repertoire and Systemic Inflammation [AUTOIMMUNITY]

Systemic lupus erythematosus is a multisystem autoimmune disease characterized by autoantibodies targeting nucleic acid–associated Ags.
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Suggested by Société Francaise d'Immunologie
May 8, 2014 2:55 PM
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Tissue-Resident Exhausted Effector Memory CD8+ T Cells Accumulate in the Retina during Chronic Experimental Autoimmune Uveoretinitis [AUTOIMMUNITY]

Experimental autoimmune uveoretinitis is a model for noninfectious posterior segment intraocular inflammation in humans. Although this disease is CD4+ T cell dependent, in the persistent phase of disease CD8+ T cells accumulate.
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Scooped by Gilbert C FAURE
May 7, 2014 2:20 PM
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Folate Receptor Alpha Autoantibodies Modulate Thyroid Function in ...

Folate Receptor Alpha Autoantibodies Modulate Thyroid Function in ... | AUTOIMMUNITY | Scoop.it
Autoantibodies that bind to the FRα and greatly impair its function were described approximately a decade ago when they were linked to cerebral folate deficiency (CFD).7 CFD is a neurometabolic disorder characterized by ...
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Scooped by Gilbert C FAURE
May 7, 2014 1:57 PM
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Only Eight in 382 Active Type 1 Diabetes Clinical Trial Projects Could Deliver a Near-Term Solution

Only Eight in 382 Active Type 1 Diabetes Clinical Trial Projects Could Deliver a Near-Term Solution | AUTOIMMUNITY | Scoop.it
From BioPortfolio: Juvenile Diabetes Cure Alliance report analyzes cure research projects that have the potential to change the lives of people with type 1. New York, NY (PRWEB) M...
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Rescooped by Gilbert C FAURE from Type 1 diabetes
May 6, 2014 10:03 AM
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Kids' Diabetes Rates Up Dramatically in 8 Years, Study Finds - U.S. News & World Report

Kids' Diabetes Rates Up Dramatically in 8 Years, Study Finds - U.S. News & World Report | AUTOIMMUNITY | Scoop.it
Kids' Diabetes Rates Up Dramatically in 8 Years, Study Finds
U.S. News & World Report
SATURDAY, May 3, 2014 (HealthDay News) -- Rates of diabetes in U.S. children have jumped sharply in just eight years, according to new research.

Via Remi Creusot
Remi Creusot's curator insight, May 6, 2014 9:27 AM

This study confirms the already suspected rate of increased T1D and T2D incidence in children. This follows the even more dramatic trend of about 3% increase per year in Europe. More and more studies are now turning to how or lifestyle influences this.

Scooped by Gilbert C FAURE
May 5, 2014 1:03 PM
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Epicutaneous application of toll-like re... [Arthritis Rheumatol. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
April 29, 2014 4:02 PM
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ASCA: At a Glance | Anti-Saccharomyces cerevisiae Antibodies

Overview of the blood test for anti-Saccharomyces cerevisiae antibodies (ASCA), used to help distinguish between Crohn disease and ulcerative colitis, the two most common types of inflammatory bowel disease (Inflammatory bowel disease affects 1 to...
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Scooped by Gilbert C FAURE
April 29, 2014 2:11 PM
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Potential diabetes therapy: scientists grow insulin-producing cells using ... - WA today

Potential diabetes therapy: scientists grow insulin-producing cells using ...
WA today
... cells, the kind lost in patients with type 1 diabetes.
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Scooped by Gilbert C FAURE
April 29, 2014 2:00 PM
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Long term effect of gut microbiota transfer on d... [J Autoimmun. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
April 28, 2014 3:30 AM
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Junctional protein problems more indications of autoimmunity

Junctional protein problems more indications of autoimmunity | AUTOIMMUNITY | Scoop.it
Junctional protein problems more indications of autoimmunity. Shimizu F, Tasaki A, Sano Y, Ju M, Nishihara H, Oishi M, Koga M, Kawai M, Kanda T. Sera from remitting and secondary progressive multiple sclerosis patients ...
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Scooped by Gilbert C FAURE
April 27, 2014 12:49 PM
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Diet, microbiota and autoimmune diseases. [Lupus. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
May 10, 2014 3:00 AM
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Automated antinuclear immunofluorescence antibody screening: A comparative study of six computer-aided diagnostic systems | Computer Science

Automated trading with performance weighted random forests and seasonality Publicati http://t.co/Ltz85DIxjG
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Scooped by Gilbert C FAURE
May 8, 2014 2:56 PM
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UF PathLabs Endocrine Autoantibody Laboratory » The Diabetes ...

UF PathLabs Endocrine Autoantibody Laboratory » The Diabetes ... | AUTOIMMUNITY | Scoop.it
UF Health Pathology Laboratories' Endocrine Autoantibody Laboratory makes autoantibody marker testing available for nearly 20 endocrine-related disorders, including Type 1 diabetes mellitus (T1DM). Our pathologists have ...
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Suggested by Société Francaise d'Immunologie
May 8, 2014 2:55 PM
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Naturally Occurring Human Phosphorylcholine Antibodies Are Predominantly Products of Affinity-Matured B Cells in the Adult [CLINICAL AND HUMAN IMMUNOLOGY]

Phosphorylcholine (PC) is a classic T-independent Ag that is exposed on apoptotic cells, oxidized phospholipids, and bacterial polysaccharides.
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Suggested by Société Francaise d'Immunologie
May 8, 2014 2:55 PM
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Disease Association and Arthritogenic Potential of Circulating Antibodies against the {alpha}1,4-Polygalacturonic Acid Moiety [AUTOIMMUNITY]

Much progress has been made in recent years on the diagnostic value, Ag specificity, and pathogenic roles of autoantibodies correlated to the development of rheumatoid arthritis (RA) in humans.
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Scooped by Gilbert C FAURE
May 7, 2014 2:19 PM
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Current Concepts and Future Directions for the Assessment of anti-nuclear antibodies

Current Concepts and Future Directions for the Assessment of anti-nuclear antibodies | AUTOIMMUNITY | Scoop.it
The detection of autoantibodies that target intracellular antigens, commonly termed anti-nuclear antibodies (ANA), is a serological hallmark in the diagnosis of systemic autoimmune rheumatic diseases (SARD).
Gilbert C FAURE's insight:

This review provides a comprehensive overview of the current status on ANA testing including automated IIF reading systems and solid phase assays and suggests an approach to interpretation of results and discusses meeting the problems of assay standardization and other persistent challenges.

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Scooped by Gilbert C FAURE
May 6, 2014 3:26 PM
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Decreased miR-146 Expression in Peripheral Blood Mononuclear Cell Correlated with Ongoing islet autoimmunity in Type 1 Diabetes Patients - Yang - Journal of Diabetes - Wiley Online Library

Decreased miR-146 Expression in Peripheral Blood Mononuclear Cell Correlated with Ongoing islet autoimmunity in Type 1 Diabetes Patients - Yang - Journal of Diabetes - Wiley Online Library | AUTOIMMUNITY | Scoop.it
NEW ARTICLE: Decreased miR-146 Expression in Peripheral Blood Mononuclear Cell Correlated with Ongoing islet autoi... http://t.co/0dKBldBk23
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Scooped by Gilbert C FAURE
May 6, 2014 4:30 AM
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The SLE Transcriptome Exhibits Evidence of Chronic Endotoxin Exposure and Has Widespread Dysregulation of Non-Coding and Coding RNAs

The SLE Transcriptome Exhibits Evidence of Chronic Endotoxin Exposure and Has Widespread Dysregulation of Non-Coding and Coding RNAs | AUTOIMMUNITY | Scoop.it
by Lihua Shi, Zhe Zhang, Angela M. Yu, Wei Wang, Zhi Wei, Ehtisham Akhter, Kelly Maurer, Patrícia Costa Reis, Li Song, Michelle Petri, Kathleen E.
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Scooped by Gilbert C FAURE
May 3, 2014 8:08 AM
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Humoral Autoimmune Responses to Insulin-Like Growth Factor II ...

Humoral Autoimmune Responses to Insulin-Like Growth Factor II ... | AUTOIMMUNITY | Scoop.it
Autoantibodies represent an immunological fingerprint in the pathological progression of cancer, and tumor-induced antibodies may be able to provide a unique insight into host-tumor interactions and the dynamic nature of carcinogenesis [6, 9– 11].
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Scooped by Gilbert C FAURE
April 29, 2014 2:45 PM
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new UK guidelines on ANCA positive...

“@Rheuma_suffolk: New UK guidelines on ANCA positive Vasculitis #rheum2014

http://t.co/ku3s14ZH7f http://t.co/zDEy8KOWFG”; #rheumedu
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Scooped by Gilbert C FAURE
April 29, 2014 2:03 PM
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UVB light attenuates the systemic immune response in CNS autoimmunity - Breuer - Annals of Neurology - Wiley Online Library

UVB light attenuates the systemic immune response in CNS autoimmunity - Breuer - Annals of Neurology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
UVB light attenuates the systemic immune response in CNS autoimmunity http://t.co/pEbEfvOkdy
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Scooped by Gilbert C FAURE
April 28, 2014 1:37 PM
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Researchers Identify Biomarker in Helping Curtail PAH Caused By Scleroderma ... - Pulmonary Hypertension News

Researchers Identify Biomarker in Helping Curtail PAH Caused By Scleroderma ... - Pulmonary Hypertension News | AUTOIMMUNITY | Scoop.it
Researchers Identify Biomarker in Helping Curtail PAH Caused By Scleroderma ...
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Scooped by Gilbert C FAURE
April 28, 2014 3:30 AM
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Sera from remitting and secondary progressive multi... [PLoS One. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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