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Suggested by
Société Francaise d'Immunologie
January 6, 2015 3:54 PM
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BAFF and a proliferation-inducing ligand (APRIL), which control B cell homeostasis, are therapeutic targets in autoimmune diseases.
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Suggested by
Société Francaise d'Immunologie
January 6, 2015 3:54 PM
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In type 1 diabetes, the pancreatic islets are an important site for therapeutic intervention because immune infiltration of the islets is well established at diagnosis.
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Scooped by
Gilbert C FAURE
January 5, 2015 2:58 PM
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Laboratory testing is essential in the diagnosis and management of patients with rheumatic disease. Editorrsquos note This article originally appeared in The Rheumatologist in a two-part series in February and April 2009.
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Scooped by
Gilbert C FAURE
December 30, 2014 11:33 AM
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RT @jclinicalinvest: Immunomodulatory agents preserve beta cells in type 1 diabetes patients http://t.co/GcCU8G5XMx #ClinicalMedicine #Cl… …
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Suggested by
Société Francaise d'Immunologie
December 27, 2014 2:10 PM
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Upregulation of IL-17 immunity and detrimental effects of IL-17 on human islets have been implicated in human type 1 diabetes. In animal models, the plasticity of Th1/Th17 cells contributes to the development of autoimmune diabetes.
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Scooped by
Gilbert C FAURE
December 26, 2014 3:41 PM
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Meta-analysis of the TNFAIP3 region in psoriasis reveals a risk haplotype that ...
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Scooped by
Gilbert C FAURE
December 25, 2014 3:54 AM
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Rescooped by
Gilbert C FAURE
from Type 1 diabetes
December 24, 2014 11:24 AM
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Scientists have created a molecular map that pinpoints genetic variants that play a role in 21 different autoimmune diseases, they report Oct. 27 in the journal Nature.
Via Remi Creusot
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Suggested by
Société Francaise d'Immunologie
December 21, 2014 3:08 PM
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Regulatory T cells (Tregs) mediate immune tolerance to self and depend on IL-2 for homeostasis. Treg deficiency, dysfunction, and instability are implicated in the pathogenesis of numerous autoimmune diseases.
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Scooped by
Gilbert C FAURE
December 20, 2014 4:29 AM
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by Tokunori Ikeda, Shinya Hirata, Koutaro Takamatsu, Miwa Haruta, Hirotake Tsukamoto, Takaaki Ito, Makoto Uchino, Yukio Ando, Seiho Nagafuchi, Yasuharu Nishimura, Satoru Senju We herein demonstrate the immune-regulatory effect of embryonic stem...
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Scooped by
Gilbert C FAURE
December 19, 2014 1:50 PM
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Targeting innate immunity for treatment of Type 1 diabetes - Immunotherapy December 2014, Vol. 6, No. 12, Pages 12... http://t.co/5xUyr12Jtk
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Scooped by
Gilbert C FAURE
December 17, 2014 1:51 PM
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Genetics and autoimmunity in Meniere disease on British Medical Journal
Meniere’s disease http://t.co/ZrxX54jzEZ
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Scooped by
Gilbert C FAURE
December 17, 2014 1:49 PM
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PLoS One. 2014 Nov 14;9(11):e112877. doi: 10.1371/journal.pone.0112877. eCollection 2014.
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Suggested by
Société Francaise d'Immunologie
January 6, 2015 3:54 PM
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In this study, we sought to understand the selective pressures shaping the Ig-producing cell repertoire in the parotid glands of primary Sjögren’s syndrome (pSS) patients before and after rituximab treatment (RTX).
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Rescooped by
Gilbert C FAURE
from Mucosal Immunity
January 6, 2015 2:37 PM
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Research on the gut microbiome and autoimmune diseases such as RA, MS, type 1 diabetes and IBD has exploded. Here, we review and analyze what it all means.
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Scooped by
Gilbert C FAURE
January 3, 2015 3:19 PM
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Background: Traditionally, antineutrophil cytoplasmic autoantibody–associated vasculitis (AAV) is histologically characterized by pauci-immune glomerulonephritis.
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Scooped by
Gilbert C FAURE
December 27, 2014 2:35 PM
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Describes how an antinuclear antibody (ANA) test is used, when an ANA test is ordered, and what the results of an ANA test might mean
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Scooped by
Gilbert C FAURE
December 26, 2014 3:42 PM
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by Elisa Corsiero, Nurhan Sutcliffe, Costantino Pitzalis, Michele Bombardieri
Sjögren’s syndrome (SS) is an autoimmune disease characterised by breach of self-tolerance towards nuclear antigens resulting in high affinity circulating autoantibodies.
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Scooped by
Gilbert C FAURE
December 26, 2014 3:40 PM
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Low doses of CMV induce autoimmune-mediated and inflammatory responses ...
Scientists have identified the cells responsible for producing anti-inflammatory IL-10 in mouse autoimmune disease models.
Via Krishan Maggon
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Suggested by
Société Francaise d'Immunologie
December 21, 2014 3:08 PM
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The nuclear receptor retinoic acid–related orphan receptor (ROR)t is required for the generation of Th17 cells, which are involved in various autoimmune diseases, including Sjögren’s syndrome (SS).
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Scooped by
Gilbert C FAURE
December 21, 2014 6:21 AM
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Immunotherapy. 2014 Dec;6(12):1239-42. doi: 10.2217/imt.14.96.
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Scooped by
Gilbert C FAURE
December 20, 2014 4:21 AM
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Researchers at the University of Tokyo have revealed that immune genes associated with susceptibilit
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Scooped by
Gilbert C FAURE
December 17, 2014 1:52 PM
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Immunology and Cell Biology focuses on the general functioning of the immune system in its broadest sense, with a particular emphasis on its cell biology.
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Scooped by
Gilbert C FAURE
December 17, 2014 1:50 PM
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MAbs. 2014 Nov 1:0. [Epub ahead of print]
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Scoop.it!
