AUTOIMMUNITY
20.9K views | +2 today
AUTOIMMUNITY
Pathology, Diagnosis and Therapies
Your new post is loading...
Your new post is loading...
Scooped by Gilbert C FAURE
December 16, 2014 2:24 PM
Scoop.it!

Antinuclear Antibodies - University of Birmingham

Antinuclear Antibodies - University of Birmingham | AUTOIMMUNITY | Scoop.it
#nhs #appraisal #revalidation great #ANA summary from the university of Birmingham @unibirmingham http://t.co/NAVi6mbKpc
No comment yet.
Scooped by Gilbert C FAURE
December 15, 2014 12:08 PM
Scoop.it!

Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes - The American Journal of Pathology

Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of Type 1 Diabetes - The American Journal of Pathology | AUTOIMMUNITY | Scoop.it
Expression of Human Leukocyte Antigen Class I in Endocrine and Exocrine Pancreatic Tissue at Onset of ... http://t.co/g3kGqTMeVc via AJP
No comment yet.
Scooped by Gilbert C FAURE
December 13, 2014 4:42 AM
Scoop.it!

JCI - Welcome

JCI - Welcome | AUTOIMMUNITY | Scoop.it
#FirstAuthorPerspective w/Rupert Kenefeck on "Follicular helper T cell signature in type 1 diabetes." http://t.co/8hlZSuIzdz #Immunology
No comment yet.
Scooped by Gilbert C FAURE
December 11, 2014 11:51 AM
Scoop.it!

The multifaceted aspects of refractory lupus nephritis, Expert Review of Clinical Immunology, Informa Healthcare

The multifaceted aspects of refractory lupus nephritis, Expert Review of Clinical Immunology, Informa Healthcare | AUTOIMMUNITY | Scoop.it
The multifaceted aspects of refractory lupus nephritis: Expert Review of Clinical Immunology, Ahead of Print.
http://t.co/ZyskCRM20i
No comment yet.
Scooped by Gilbert C FAURE
December 9, 2014 1:18 PM
Scoop.it!

Sex Differences in Monocyte Activation in Systemic Lupus Erythematosus (SLE)

Sex Differences in Monocyte Activation in Systemic Lupus Erythematosus (SLE) | AUTOIMMUNITY | Scoop.it
by Wei Jiang, Lumin Zhang, Ren Lang, Zihai Li, Gary Gilkeson
Introduction TLR7/8 and TLR9 signaling pathways have been extensively studied in systemic lupus erythematosus (SLE) as possible mediators of disease.
No comment yet.
Suggested by Société Francaise d'Immunologie
December 7, 2014 12:32 PM
Scoop.it!

Delta-like 1-Mediated Notch Signaling Enhances the In Vitro Conversion of Human Memory CD4 T Cells into FOXP3-Expressing Regulatory T Cells [CLINICAL AND HUMAN IMMUNOLOGY]

FOXP3-expressing regulatory T cells (Treg) are essential for the prevention of autoimmunity and were shown to be reduced and/or dysfunctional in several autoimmune diseases.
No comment yet.
Suggested by Société Francaise d'Immunologie
December 2, 2014 2:12 PM
Scoop.it!

Autoimmunity: Basophils in autoimmune and inflammatory diseases - Nature.com

Autoimmunity: Basophils in autoimmune and inflammatory diseases Nature.com Importantly, the phenotype, cytokine/chemokine response and functions of basophils vary extensively depending on the stimuli they receive during haematopoiesis.7 In...
No comment yet.
Scooped by Gilbert C FAURE
December 1, 2014 12:54 PM
Scoop.it!

Autoimmunity: Basophils in autoimmune and inflammatory diseases - Nature.com

Autoimmunity: Basophils in autoimmune and inflammatory diseases
Nature.com
TH2 cells along with basophils (via IL-4, IL-6 and BAFF) induce B-cell activation, differentiation and autoantibody production (including IgE).
No comment yet.
Scooped by Gilbert C FAURE
November 26, 2014 2:16 PM
Scoop.it!

Role of Type 1 diabetes associated SNPs on risk of autoantibody positivity in the TEDDY Study

RT @NatureRevEndo: New #genetic risk factors for autoantibody positivity identified in patients with #T1DM http://t.co/kWDPO4Nj03 #diabete…
No comment yet.
Scooped by Gilbert C FAURE
November 26, 2014 1:56 PM
Scoop.it!

Keystone Symposia Conference | Autoimmunity and Tolerance - Program

Keystone Symposia, a non-profit organization dedicated to connecting the scientific community for the benefit of the world community and accelerating life science discovery, conducts scientific conferences on biomedical and life science topics in...
No comment yet.
Scooped by Gilbert C FAURE
November 24, 2014 2:06 PM
Scoop.it!

Fatty fish consumption and risk of latent autoimmune diabetes in adults - Nature.com

Fatty fish consumption and risk of latent autoimmune diabetes in adults - Nature.com | AUTOIMMUNITY | Scoop.it
Nutrition & Diabetes is a peer-reviewed, open access online journal publishing clinical, metabolic, genetic and epidemiological studies that describe methodologies, mechanisms, and associations in relation to diabetes and nutrition-related diseases...
No comment yet.
Scooped by Gilbert C FAURE
November 24, 2014 12:26 PM
Scoop.it!

Epithelial Transport of Immunogenic and Toxic Gliadin Peptides In Vitro

Epithelial Transport of Immunogenic and Toxic Gliadin Peptides In Vitro | AUTOIMMUNITY | Scoop.it
by Christian Zimmermann, Silvia Rudloff, Günter Lochnit, Sevgi Arampatzi, Wolfgang Maison, Klaus-Peter Zimmer
Scope Celiac disease is an autoimmune disorder caused by failure of oral tolerance against gluten in genetically predisposed individuals.
No comment yet.
Scooped by Gilbert C FAURE
November 23, 2014 2:33 PM
Scoop.it!

The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases

Background:
The extracellular domains of cytokine receptors are released during inflammation, but little is known about the shedding of Toll-like receptors (TLR) and whether they can be used as diagnostic biomarkers.
No comment yet.
Scooped by Gilbert C FAURE
December 16, 2014 10:14 AM
Scoop.it!

The TIGIT/CD226 axis regulates human T cell function. - PubMed - NCBI

J Immunol. 2012 Apr 15;188(8):3869-75. doi: 10.4049/jimmunol.1103627. Epub 2012 Mar 16. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Gilbert C FAURE's insight:

These data demonstrate that TIGIT can inhibit T cell functions by competing with CD226 and can also directly inhibit T cells in a T cell-intrinsic manner. Our results provide evidence for a novel role of this alternative costimulatory pathway in regulating human T cell responses associated with autoimmune di

No comment yet.
Suggested by Société Francaise d'Immunologie
December 13, 2014 2:32 PM
Scoop.it!

SLAM-SAP Signaling Promotes Differentiation of IL-17-Producing T Cells and Progression of Experimental Autoimmune Encephalomyelitis [AUTOIMMUNITY]

IL-17 plays critical roles in host defenses, combating bacterial and fungal infections, as well as the pathogenesis of autoimmune diseases such as experimental autoimmune encephalomyelitis (EAE).
No comment yet.
Scooped by Gilbert C FAURE
December 12, 2014 4:36 AM
Scoop.it!

Antiphospholipid Syndrome: Avoiding Thrombotic and Obstetric Issues - Pharmacy Times

Antiphospholipid Syndrome: Avoiding Thrombotic and Obstetric Issues - Pharmacy Times | AUTOIMMUNITY | Scoop.it
Knowledge gaps regarding antiphospholipid syndrome pose challenges.
No comment yet.
Scooped by Gilbert C FAURE
December 11, 2014 11:50 AM
Scoop.it!

Th1/Th17 Plasticity Is a Marker of Advanced β Cell Autoimmunity and Impaired Glucose Tolerance in Humans.

Th1/Th17 Plasticity Is a Marker of Advanced β Cell Autoimmunity and Impaired Glucose Tolerance in Humans. | AUTOIMMUNITY | Scoop.it
Authors: Linnea Reinert-Hartwall, Jarno Honkanen, Harri M Salo, Janne K Nieminen, Kristiina Luopajärvi, Taina Härkönen, Riitta Veijola, Olli Simell, Jorma Ilonen, Aleksandr Peet, Vallo Tillmann, Mikael Knip, Outi Vaarala, Discipline: Medicine, Type:...
No comment yet.
Scooped by Gilbert C FAURE
December 8, 2014 1:58 PM
Scoop.it!

Antidesmocollin 1 autoantibody negative subcorneal pustular dermatosis-type IgA pemphigus associated with multiple myeloma - España - 2014 - British Journal of Dermatology - Wiley Online Library

Antidesmocollin 1 autoantibody negative subcorneal pustular dermatosis-type IgA pemphigus associated with multiple myeloma - España - 2014 - British Journal of Dermatology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Antidesmocollin 1 autoantibody negative subcorneal pustular dermatosis‐type IgA pemphigus associated with multip... http://t.co/nY0jI5ZQlD
No comment yet.
Scooped by Gilbert C FAURE
December 3, 2014 8:46 AM
Scoop.it!

Islet transplantation for Type 1 diabetes: where are we now?, Expert Review of Clinical Immunology, Informa Healthcare

Islet transplantation for Type 1 diabetes: where are we now?, Expert Review of Clinical Immunology, Informa Healthcare | AUTOIMMUNITY | Scoop.it
Islet transplantation for Type 1 diabetes: where are we now?: Expert Review of Clinical Immunology, Ahead of P... http://t.co/gPp384AagT
No comment yet.
Suggested by Société Francaise d'Immunologie
December 2, 2014 2:12 PM
Scoop.it!

C4 Deficiency Is a Predisposing Factor for Streptococcus pneumoniae-Induced Autoantibody Production [AUTOIMMUNITY]

Reductions in C4 levels may predispose individuals to infection with encapsulated bacteria as well as autoimmunity. In this study, we examined the role C4 has in protection against Streptococcus pneumoniae–induced autoimmunity.
No comment yet.
Scooped by Gilbert C FAURE
December 1, 2014 12:52 PM
Scoop.it!

Anti-dsDNA antibodies as a classification criterion and a diagnostic marker for systemic lupus erythematosus: critical remarks - Rekvig - 2014 - Clinical & Experimental Immunology - Wiley Online Li...

Anti-dsDNA antibodies as a classification criterion and a diagnostic marker for systemic lupus erythematosus: critical remarks - Rekvig - 2014 - Clinical & Experimental Immunology - Wiley Online Li... | AUTOIMMUNITY | Scoop.it
AntidsDNA antibodies as aclassification criterion and a diagnostic marker for SEL Clinical & Experimental Immunology http://t.co/BhTBDH89sn
No comment yet.
Scooped by Gilbert C FAURE
November 26, 2014 2:15 PM
Scoop.it!

Infant Feeding in Relation to Islet Autoimmunity and Type 1 Diabetes in Genetically Susceptible Children: The MIDIA Study

Infant Feeding in Relation to Islet Autoimmunity and Type 1 Diabetes in Genetically Susceptible Children: MIDIA Study http://t.co/csN3FFwN1E
No comment yet.
Scooped by Gilbert C FAURE
November 24, 2014 2:06 PM
Scoop.it!

ChemoCentryx's Orally Administered C5aR Inhibitor CCX168 Shows Benefit in ... - MarketWatch

ChemoCentryx's Orally Administered C5aR Inhibitor CCX168 Shows Benefit in ... - MarketWatch | AUTOIMMUNITY | Scoop.it
ChemoCentryx's Orally Administered C5aR Inhibitor CCX168 Shows Benefit in ...
No comment yet.
Scooped by Gilbert C FAURE
November 24, 2014 2:05 PM
Scoop.it!

Anti-Ribosomal P Antibody Is a Key Autoantibody...

Anti-Ribosomal P Antibody Is a Key Autoantibody... | AUTOIMMUNITY | Scoop.it
Complications of neuropsychiatric systemic lupus erythematosus (NP-SLE) are associated with the morbidity and mortality of patients with SLE.
No comment yet.
Scooped by Gilbert C FAURE
November 23, 2014 2:34 PM
Scoop.it!

B cell epitope spreading: Mechanisms and contribution to autoimmune diseases

“@ImmunologyNews: Evidence demonstrates how B cell epitope spreading results in autoimmunity http://t.co/fKrq9pwgWm”
No comment yet.