NeuroImmunology
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Scooped by Gilbert C FAURE
December 30, 2014 2:31 PM
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Cerebrospinal Fluid (CSF) Neuronal Biomarkers across the Spectrum of HIV Infection: Hierarchy of Injury and Detection

Cerebrospinal Fluid (CSF) Neuronal Biomarkers across the Spectrum of HIV Infection: Hierarchy of Injury and Detection | NeuroImmunology | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Scooped by Gilbert C FAURE
December 30, 2014 11:16 AM
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Evaluation of incidence and clinical features of antibody-associate... - PubMed - NCBI

Behav Neurol. 2014;2014:935379. doi: 10.1155/2014/935379. Epub 2014 Mar 17. Research Support, Non-U.S. Gov't
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Scooped by Gilbert C FAURE
December 26, 2014 3:43 PM
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Interleukin-34 Restores Blood–Brain Barrier Integrity by Upregulating Tight Junction Proteins in Endothelial Cells

Interleukin-34 Restores Blood–Brain Barrier Integrity by Upregulating Tight Junction Proteins in Endothelial Cells | NeuroImmunology | Scoop.it
by Shijie Jin, Yoshifumi Sonobe, Jun Kawanokuchi, Hiroshi Horiuchi, Yi Cheng, Yue Wang, Tetsuya Mizuno, Hideyuki Takeuchi, Akio Suzumura Interleukin-34 (IL-34) is a newly discovered cytokine as an additional ligand for colony stimulating factor-1...
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Scooped by Gilbert C FAURE
December 22, 2014 1:34 PM
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Molecular targeted therapy against B cells in multiple sclerosis - Miyazaki - 2014 - Clinical and Experimental Neuroimmunology - Wiley Online Library

Molecular targeted therapy against B cells in multiple sclerosis - Miyazaki - 2014 - Clinical and Experimental Neuroimmunology - Wiley Online Library | NeuroImmunology | Scoop.it
Molecular targeted therapy against B cells in multiple sclerosis Clinical and Experimental Neuroimmunology http://t.co/EjxrfgsoQM
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Scooped by Gilbert C FAURE
December 21, 2014 3:03 PM
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Beta-amyloid: the emperor really does have no clothes

Beta-amyloid: the emperor really does have no clothes | NeuroImmunology | Scoop.it
Yesterday, Roche (OTCQX:RHHBY) announced its decision to discontinue its Phase 3 study of gantenerumab, its experimental anti-amyloid antibody, in early Alzheimer’s Disease.
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Scooped by Gilbert C FAURE
December 21, 2014 11:36 AM
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Cognition, Brain Atrophy, and Cerebrospinal Fluid Biomarkers Change... - PubMed - NCBI

J Alzheimers Dis. 2014 Dec 12. [Epub ahead of print]
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Scooped by Gilbert C FAURE
December 21, 2014 11:35 AM
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High expression of CXCR3 is an independent prognostic factor in glioblastoma patients that promotes an invasive phenotype - Online First - Springer

High expression of CXCR3 is an independent prognostic factor in glioblastoma patients that promotes an invasive phenotype - Online First - Springer | NeuroImmunology | Scoop.it
High expression of CXCR3 is an independent prognostic factor in glioblastoma patients that promotes an invasiv... http://t.co/OUbWTGkAtm
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Scooped by Gilbert C FAURE
December 19, 2014 1:37 PM
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Serum IgG Antibody Levels to Periodontal Microbiota Are Associated with Incident Alzheimer Disease

Serum IgG Antibody Levels to Periodontal Microbiota Are Associated with Incident Alzheimer Disease | NeuroImmunology | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Scooped by Gilbert C FAURE
December 17, 2014 12:53 PM
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Lancet Neurology sur Twitter

Lancet Neurology sur Twitter | NeuroImmunology | Scoop.it
Our deepest gratitude to the European Multiple Sclerosis Platform for such nice greeting card! pic.twitter.com/vf4AnhwGVZ
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Scooped by Gilbert C FAURE
December 16, 2014 8:25 AM
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Evolution of multiple sclerosis in France since the beginning of hepatitis B vaccination - Springer

Evolution of multiple sclerosis in France since the beginning of hepatitis B vaccination - Springer | NeuroImmunology | Scoop.it
Evolution of multiple sclerosis in France since the beginning of hepatitis B vaccination - Springer http://t.co/W2bxk5tEu3 [ New Study ]
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Scooped by Gilbert C FAURE from Cancer Pathways inhibitors Collection
December 15, 2014 10:21 AM
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Frontiers | Gliomas and the vascular fragility of the blood brain barrier | Frontiers in Cellular Neuroscience

Astrocytes, members of the glial family, interact through the exchange of soluble factors or by directly contacting neurons and other brain cells, such as microglia and endothelial cells. Astrocyti...

Via Krishan Maggon
Krishan Maggon 's curator insight, December 15, 2014 4:03 AM
Front. Cell. Neurosci., 12 December 2014 | doi: 10.3389/fncel.2014.00418Gliomas and the vascular fragility of the blood brain barrierLuiz Gustavo Dubois1†, Loraine Campanati2†, Cassia Righy1, Isabella D’Andrea-Meira1, Tania Cristina Leite de Sampaio e Spohr1, Isabel Porto-Carreiro1, Claudia Maria Pereira3, Joana Balça-Silva4, Suzana Assad Kahn1, Marcos F. DosSantos2, Marcela de Almeida Rabello Oliveira5, Adriana Ximenes-da-Silva5, Maria Celeste Lopes4, Eduardo Faveret1, Emerson Leandro Gasparetto1 and Vivaldo Moura-Neto1,2*
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December 13, 2014 6:34 AM
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Parkinson's Vaccine Goes Into Phase I Clinical Trial - Science 2.0

Parkinson's Vaccine Goes Into Phase I Clinical Trial - Science 2.0 | NeuroImmunology | Scoop.it
Parkinson's Vaccine Goes Into Phase I Clinical Trial
Science 2.0
The vaccine, called AFFITOPE® PD03A , targets a protein called alpha-Synuclein.
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Scooped by Gilbert C FAURE
December 12, 2014 1:39 PM
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Data published on ANG4043, anti-HER2 monoclonal antibody for treatment of brain metastases

Data published on ANG4043, anti-HER2 monoclonal antibody for treatment of brain metastases | NeuroImmunology | Scoop.it
Results in molecular cancer therapeutics demonstrated significant prolonged survival in mice with intracranial HER2+ tumors after IV injections of ANG4043Angiochem, a clinical stage...
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December 30, 2014 11:18 AM
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Paraneoplastic Ma Antigen–Like 1 as a Potential Prognostic B... : Pancreas

Paraneoplastic Ma Antigen–Like 1 as a Potential Prognostic B... : Pancreas | NeuroImmunology | Scoop.it
ObjectiveThe present study aimed to identify novel useful clinical biomarker at early stages and to elucidate the molecular background of carcinogenesis in human pancreatic ductal adenocarcinomas (PDACs).
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Scooped by Gilbert C FAURE from Multiple sclerosis New Drugs Review
December 27, 2014 2:30 PM
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Cell Research - STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation

Cell Research - STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation | NeuroImmunology | Scoop.it
Cell death and differentiation is a monthly research journal focused on the exciting field of programmed cell death and apoptosis.

Via Krishan Maggon
Krishan Maggon 's curator insight, November 25, 2014 3:42 AM

Cell Research advance online publication 21 November 2014; doi: 10.1038/cr.2014.154

STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation
OPEN

Wanqiang Sheng1,2, Fan Yang1, Yi Zhou3, Henry Yang1, Pey Yng Low4, David Michael Kemeny4, Patrick Tan1,5, Akira Moh7, Mark H Kaplan7,8, Yongliang Zhang4 and Xin-Yuan Fu1,3,6,8

1Cancer Science Institute of Singapore, YLL School of Medicine, National University of Singapore, Singapore2Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore3Department of Biochemistry, YLL School of Medicine, National University of Singapore, Singapore4Immunology Programme and Department of Microbiology, YLL School of Medicine, National University of Singapore, Singapore5Cancer and Stem Cell Biology, Duke-NUS Graduate Medical School, Singapore6Neurobiology Programme, Life Sciences Institute, National University of Singapore, Singapore7Departments of Pediatrics and Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA8Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202, USA

Correspondence: Yongliang Zhang, E-mail: miczy@nus.edu.sg; Xin-Yuan Fu, E-mail: xin-yuan_fu@nuhs.edu.sg

Received 22 September 2014; Revised 29 September 2014; Accepted 9 October 2014
Advance online publication 21 November 2014

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December 25, 2014 2:47 PM
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Novel roles of microglia - Nakanishi - 2014 - Clinical and Experimental Neuroimmunology - Wiley Online Library

Novel roles of microglia - Nakanishi - 2014 - Clinical and Experimental Neuroimmunology - Wiley Online Library | NeuroImmunology | Scoop.it
Novel roles of microglia Nakanishi 2014 Clinical and Experimental Neuroimmunology Wiley Online Library http://t.co/okleFWPZEl
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Scooped by Gilbert C FAURE
December 22, 2014 1:28 PM
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Antigen Dependently Activated Cluster of Differentiation 8-Positive T Cells Cause Perforin-Mediated Neurotoxicity in Experimental Stroke

"Antigen Dependently Activated Cluster of Differentiation 8-Positive T Cells Cause Perforin-Mediated Neurotoxicity http://t.co/0IvAz5J6l6
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Scooped by Gilbert C FAURE
December 21, 2014 11:37 AM
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Cerebrospinal fluid complement activation in patients with pneumoco... - PubMed - NCBI

J Infect. 2014 Jun;68(6):542-7. doi: 10.1016/j.jinf.2013.12.016. Epub 2014 Jan 9. Research Support, Non-U.S. Gov't
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Scooped by Gilbert C FAURE
December 21, 2014 11:36 AM
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Roche shares tumble after Alzheimer’s drug failure

Roche shares tumble after Alzheimer’s drug failure | NeuroImmunology | Scoop.it
Double-blow for Swiss company as it also announces mixed results for breast cancer drug tests.
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Scooped by Gilbert C FAURE
December 19, 2014 1:43 PM
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Chemokine CXCL1 enhances inflammatory pain and increases NMDA recep... - PubMed - NCBI

Exp Neurol. 2014 Nov;261:328-36. doi: 10.1016/j.expneurol.2014.05.014. Epub 2014 May 20. Research Support, N.I.H., Extramural
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Scooped by Gilbert C FAURE
December 18, 2014 11:35 AM
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The choroid plexus and the paradox of interferons in the aging brain. - PubMed - NCBI

Cytokine. 2014 Dec 12. pii: S1043-4666(14)00604-8. doi: 10.1016/j.cyto.2014.11.021. [Epub ahead of print]
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Scooped by Gilbert C FAURE
December 16, 2014 1:49 PM
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Azathioprine: Old Drug, New Data - Multiple Sclerosis Discovery Forum

Azathioprine: Old Drug, New Data - Multiple Sclerosis Discovery Forum | NeuroImmunology | Scoop.it
Multiple Sclerosis Discovery Forum
Azathioprine: Old Drug, New Data
Multiple Sclerosis Discovery Forum
Call it That '80s Drug.
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Scooped by Gilbert C FAURE
December 15, 2014 12:10 PM
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Transferrin' bispecific antibodies across the blood–brain barrier - Nature.com

Transferrin' bispecific antibodies across the blood–brain barrier Nature.com The blood–brain barrier (BBB) is a notoriously difficult obstacle for therapeutic agents — particularly large molecules such as antibodies — that have targets within the...
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Scooped by Gilbert C FAURE
December 13, 2014 6:35 AM
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Programme Details | BNA2015: Festival of Neuroscience

Programme Details | BNA2015: Festival of Neuroscience | NeuroImmunology | Scoop.it
The neuroimmunology of stroke: inflammation, immunosuppression, infection and injury #neuroscience #2015neurofest http://t.co/ppQPvBzFFr
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Scooped by Gilbert C FAURE
December 12, 2014 1:40 PM
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Angiochem Publishes Data on ANG4043, a Brain-Penetrant Anti-HER2 Monoclonal Antibody for Treatment on Brain Metastases | Angiochem: Peptide-Antibody Conjugates that Cross the Blood Brain Barrier

RT @JFPariseau: Great new paper from investee company #Angiochem showing its platform can deliver antibodies to BBB http://t.co/cUfWYgeGfh
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