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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:04 PM
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And Reindl et al. review the spectrum of MOG antibody-associated demyelinating diseases http://t.co/tP5Iz4v36e (£) #newfromnrneurol
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:03 PM
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Neuropsychiatric disease in murine lupus is dependent on the TWEAK/Fn14 pathway [Journal of Autoimmunity] http://t.co/dTZcLltGNy
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:02 PM
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Open Access: Changes to anti-JCV antibody levels in a Swedish national MS cohort [MULTIPLE SCLEROSIS] http://t.co/wUQpUtXu4N
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:02 PM
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Background: Peripheral nerve injuries that provoke neuropathic pain are associated with chronic infl.
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:01 PM
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PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:00 PM
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:00 PM
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PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 1:59 PM
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Sanofi's Genzyme says making progress with MS drugsReuters"Neurologists may feel threatened, but they will have to understand how the immune system works and how to handle, so I don't think autoimmunity will be a big problem," she said.
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 1:58 PM
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In 1960, Simpson was the first to propose that the pathogenesis of MG was an autoimmune reaction that involved an antibody specific for a neuromuscular junction protein. Which turned out to be correct, the most common ...
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:04 PM
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Case Reports in Neurological Medicine is a peer-reviewed, open access journal that publishes case reports in all areas of neurological medicine.
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:03 PM
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JAMA Network | JAMA Neurology | Neuromyelitis Optica and Non–Organ-Specific Autoimmunity http://t.co/znvxGkKDFZ
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:02 PM
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Sung-Min Kim, Patrick Waters, Mark Woodhall, Jee-Young Kim, Jee-Eun Kim, Ji Won Yang, Jun-Soon Kim, Jung-Joon Sung, Kyung Seok Park, Kwang-Woo LeeJan 17, 2013; 0:135245851-135245851 (Utility of aquaporin-4 antibody assay in patients with neuromyelitis...
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:01 PM
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The discovery of a novel serum autoantibody (termed NMO-IgG or AQP4-Ab) in a subset of patients in 2004 has revived interest in neuromyelitis optica (NMO).
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:01 PM
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Ped Neuro Res Alison Christy MD/PhD published in Journal of Autoimmunity. Check it out here: http://t.co/s3uZJJNp #MDCHAT #MEDED #hcsm
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 2:00 PM
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Brain auto-antibodies Autoimmunity were proposed to clarify SLE neuropsychiatric disorders and found for being elevated prior to the start of clinical symptoms. The investigators assessed cognition in Caucasian SLE women ...
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 1:59 PM
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With a few exceptions, antineuronal antibodies are believed to be “markers” for autoimmunity but probably do not directly mediate neuronal injury. For some syndromes recent evidence implicates cellular-mediated ...
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Scooped by
Gilbert C FAURE
from AUTOIMMUNITY
January 5, 2014 1:59 PM
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Attacks potassium channels in glial cells – the brain's myelin forming neuron protectors.
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Myelin oligodendrocyte glycoprotein (MOG) has been identified as a target of demyelinating autoantibodies in animal models of inflammatory demyelinating diseases of the CNS, such as multiple sclerosis (MS). Numerous studies have aimed to establish a role for MOG antibodies in patients with MS, although the results have been controversial. Cell-based immunoassays using MOG expressed in mammalian cells have demonstrated the presence of high-titre MOG antibodies in paediatric patients with acute disseminated encephalomyelitis, MS, aquaporin-4-seronegative neuromyelitis optica, or isolated optic neuritis or transverse myelitis, but only rarely in adults with these disorders. These studies indicate that MOG antibodies could be associated with a broad spectrum of acquired human CNS demyelinating diseases. This Review article discusses the current literature on MOG antibodies, their potential clinical relevance, and their role in the pathogenesis of MOG antibody-associated demyelinating disorders.