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Read More About Association Of British Neurologists Releases New guidelines For Multiple Sclerosis. 
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Rev Neurol (Paris). 2014 Oct;170(10):561-3. doi: 10.1016/j.neurol.2014.07.001. Epub 2014 Aug 30. Review
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Immunomodulatory properties of the IL-6 cytokine family in multiple sclerosis: Multiple sclerosis (MS) is a ch... http://t.co/EsvhuUAquS
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J Neuropathol Exp Neurol. 2015 Jul;74(7):672-687.
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Alzheimers Dement. 2015 Jun 9. pii: S1552-5260(15)00176-4. doi: 10.1016/j.jalz.2015.02.009. [Epub ahead of print]
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RT @GreenJournal: Critical role for prokineticin 2 in CNS autoimmunity http://t.co/UqwEKYOOEy #Neurology
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JAMA Neurol. 2015 Apr 13. doi: 10.1001/jamaneurol.2015.48. [Epub ahead of print]
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by Euan Ramsay Orr Allan, Robin Michael Yates
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Ferritin levels in the cerebrospinal fluid predict Alzheimer/'s disease outcomes and are regulated by APOE : ... - http://t.co/dXBidleUNV
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J Med Econ. 2015 Jun 9:1-24. [Epub ahead of print]
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From
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Anti-neuronal autoimmune encephalitis (AIE) comprises a recently characterized group of immune-mediated disorders that result in limbic, multifocal, or diffuse encephalitis due...
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PLoS One. 2015 Jun 5;10(6):e0129291. doi: 10.1371/journal.pone.0129291.
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"It was exactly what we thought it couldn't be."
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RT The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis http://t.co/1neIpf6GmR
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Therapeutic implications of the choroid plexus-cerebrospinal fluid interface in neuropsychiatric disorders http://t.co/0tGsLCiz6C
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Multiple sclerosis (MS) affects the brain and spinal cord. MS is a disease in which the immune system attacks the protective sheath (myelin) that covers our nerves. Myelin damage disrupts communication between the brain and the rest of the body.
Krishan Maggon 's curator insight,
June 19, 2015 3:33 AM
NATURE | LETTER 日本語要約Drug-based modulation of endogenous stem cells promotes functional remyelination in vivoFadi J. Najm,Mayur Madhavan,Anita Zaremba,Elizabeth Shick,Robert T. Karl,Daniel C. Factor,Tyler E. Miller,Zachary S. Nevin,Christopher Kantor,Alex Sargent,Kevin L. Quick,Daniela M. Schlatzer,Hong Tang,Ruben Papoian,Kyle R. Brimacombe,Min Shen,Matthew B. Boxer,Ajit Jadhav,Andrew P. Robinson,Joseph R. Podojil,Stephen D. Miller,Robert H. Miller& Paul J. TesarAffiliationsContributionsCorresponding authorsNature 522, 216–220 (11 June 2015) doi:10.1038/nature14335Received 01 April 2014 Accepted 18 February 2015 Published online 20 April 2015
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Autoimmun Rev. 2015 Jun 9. pii: S1568-9972(15)00132-9. doi: 10.1016/j.autrev.2015.06.001. [Epub ahead of print] REVIEW
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Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody http://t.co/DyoKdAAUFy
Krishan Maggon 's curator insight,
June 18, 2015 8:21 AM
SCIENTIFIC REPORTS | ARTICLE OPEN Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibodyWenjie Luo,Wencheng Liu,Xiaoyan Hu,Mary Hanna,April Caravaca& Steven M. PaulAffiliationsContributionsCorresponding authorsScientific Reports 5, Article number: 11161 doi:10.1038/srep11161Received 03 February 2015 Accepted 18 May 2015 Published 09 June 2015
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Via Krishan Maggon
Krishan Maggon 's curator insight,
June 11, 2015 12:20 AM
NATURE | LETTER HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammationVictoria A. Blaho,Sylvain Galvani,Eric Engelbrecht,Catherine Liu,Steven L. Swendeman,Mari Kono,Richard L. Proia,Lawrence Steinman,May H. Han& Timothy HlaAffiliationsContributionsCorresponding authorNature (2015) doi:10.1038/nature14462Received 16 March 2014 Accepted 08 April 2015 Published online 08 June 2015
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J Neuroimmunol. 2015 Mar 15;280:16-20. doi: 10.1016/j.jneuroim.2015.01.009. Epub 2015 Jan 28. Research Support, Non-U.S. Gov't
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Via Krishan Maggon
Krishan Maggon 's curator insight,
May 14, 2015 3:22 AM
Sci Transl Med 13 May 2015:
Vol. 7, Issue 287, p. 287ra74 Sci. Transl. Med. DOI: 10.1126/scitranslmed.aaa8038RESEARCH ARTICLE MULTIPLE SCLEROSIS Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosisYonghao Cao1,*, Brittany A. Goods2,*, Khadir Raddassi1, Gerald T. Nepom3, William W. Kwok3,4,J. Christopher Love5,6,† and David A. Hafler1,6,†,‡+Author Affiliations 1Departments of Neurology and Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.2Department of Biological Engineering, Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.3Benaroya Research Institute, Virginia Mason Research Center, Seattle, WA 98101, USA.4Department of Medicine, University of Washington, Seattle, WA 98101, USA.5Department of Chemical Engineering, Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA 02139, USA.6The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.+Author Notes ↵* These authors contributed equally to this work. ↵† These authors contributed equally to this work. ↵‡Corresponding author. E-mail: david.hafler@yale.edu
The Yale-led team analyzed T cell populations from 23 MS patients and 22 healthy controls. Existing drugs target the MS-specific cytokines identified in the study and should be a promising new treatment for the disease, the authors say. http://news.yale.edu/2015/05/13/yale-researchers-solve-multiple-sclerosis-puzzle
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RT @GreenJournal: The June issue of Neurology: Neuroimmunology & Neuroinflammation is here! http://t.co/QGzg2E7lx7 #Neurology
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Article Abstract: from British Journal of Cancer - AOP - nature.com science feedsClick Here To Read Full Article Visit British Journal of Cancer - AOP - nature.com science feeds for more great articles.
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Glioblastoma antigen discovery—foundations for immunotherapy http://t.co/gznYTR10Za
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Sphingolipids are important in many brain functions but their role in Alzheimer’s disease (AD) is not completely defined. A major limit is availability of fresh brain tissue with defined AD pathology. Via Krishan Maggon
Krishan Maggon 's curator insight,
May 5, 2015 5:50 AM
Citation: Fonteh AN, Ormseth C, Chiang J, Cipolla M, Arakaki X, et al. (2015) Sphingolipid Metabolism Correlates with Cerebrospinal Fluid Beta Amyloid Levels in Alzheimer’s Disease. PLoS ONE 10(5): e0125597. doi:10.1371/journal.pone.0125597 |
