AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
April 12, 2015 2:21 PM
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Epitope mapping of the N-terminal portion of tissue transglutaminase protein antigen to identify linear epitopes in celiac disease. - PubMed - NCBI

Epitope mapping of the N-terminal portion of tissue transglutaminase protein antigen to identify linear epitopes in celiac disease. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
J Pept Sci. 2014 Sep;20(9):689-95. doi: 10.1002/psc.2650. Epub 2014 May 15.
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Scooped by Gilbert C FAURE
April 11, 2015 4:35 AM
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EUROPattern Suite technology for computer-aided immunofluorescence microscopy in autoantibody diagnostics. - PubMed - NCBI

EUROPattern Suite technology for computer-aided immunofluorescence microscopy in autoantibody diagnostics. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Lupus. 2015 Apr;24(4-5):516-29. doi: 10.1177/0961203314559635.
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Rescooped by Gilbert C FAURE from Autoimmune diseases (Lupus, RA), Vaccines and Stem Cell Therapies Highlights
April 8, 2015 1:23 PM
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TREML4 As A New Regulator of Autoimmunity in Systemic Lupus Erythematosus - Lupus News Today

TREML4 As A New Regulator of Autoimmunity in Systemic Lupus Erythematosus - Lupus News Today | AUTOIMMUNITY | Scoop.it
Read how researchers identified a new molecule – TREML4 – that promotes TLR7-mediated release of inflammatory cytokines in systemic lupus erythematosus.

Via Krishan Maggon
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Scooped by Gilbert C FAURE
April 4, 2015 4:27 PM
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Science Translational Medicine | From AAAS

RT @ARD_BMJ: Blocking #autoantibody generation in the initiation of rheumatoid #arthritis #rheumedu http://t.co/7WvbKfCCDt
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Scooped by Gilbert C FAURE
April 4, 2015 3:00 AM
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Frontiers | Mononuclear cells and vascular repair in HHT | Genetic Disorders

Hereditary hemorrhagic telangiectasia (HHT) or Rendu-Osler-Weber disease is a rare genetic vascular disorder known for its endothelial dysplasia causing arteriovenous malformations and severe bleed...
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Scooped by Gilbert C FAURE
April 2, 2015 2:40 AM
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Meta-Analysis of MicroRNA-146a rs2910164 G>C Polymorphism Association with Autoimmune Diseases Susceptibility, an Update Based on 24 Studies

Meta-Analysis of MicroRNA-146a rs2910164 G>C Polymorphism Association with Autoimmune Diseases Susceptibility, an Update Based on 24 Studies | AUTOIMMUNITY | Scoop.it
by Changzheng Li, Weijun Fu, Yu Zhang, Liang Zhou, Zhi Mao, Weiran Lv, Juan Li, Ye Zhou
Background Published data showed that the susceptibility of autoimmune diseases (ADs) was associated with the polymorphism rs2910164 in microRNA-146a (miR-146a).
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Scooped by Gilbert C FAURE
April 1, 2015 2:57 PM
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Antinuclear Antibodies and the IFA Test

Antinuclear Antibodies and the IFA Test | AUTOIMMUNITY | Scoop.it
Antinuclear antibodies (ANAs) and the IFA test
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Scooped by Gilbert C FAURE
March 31, 2015 2:55 PM
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Case report: lupus nephritis with autoantibodies to complement alternative ... - BMC Blogs Network

Glomerulonephritis is one of the most severe complications of lupus, a systemic disease with multi-organ involvement, with tissue damage produced mainly by complement activation.
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Scooped by Gilbert C FAURE
March 31, 2015 12:36 PM
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Autoimmunity and the Gut

Autoimmunity and the Gut | AUTOIMMUNITY | Scoop.it
Autoimmune diseases have increased dramatically worldwide since World War II.
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Scooped by Gilbert C FAURE
March 30, 2015 3:06 PM
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Leaky gut and autoimmune diseases. - PubMed - NCBI

Leaky gut and autoimmune diseases. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Clin Rev Allergy Immunol. 2012 Feb;42(1):71-8. doi: 10.1007/s12016-011-8291-x. Research Support, N.I.H., Extramural; Review
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Rescooped by Gilbert C FAURE from Autoimmune diseases (Lupus, RA), Vaccines and Stem Cell Therapies Highlights
March 29, 2015 6:01 AM
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Progress with the use of monoclonal antibodies for the treatment of systemic lupus erythematosus, Immunotherapy, Future Medicine

Progress with the use of monoclonal antibodies for the treatment of systemic lupus erythematosus, Immunotherapy, Future Medicine | AUTOIMMUNITY | Scoop.it

In recent years, significant progress has been made in the use of monoclonal antibodies in the treatment of systemic lupus erythematosus (SLE). Advances in our understanding of the complexity of SLE immunopathogenesis have led to the testing of several biologic agents in clinical trials. Monoclonal therapies currently emerging or under development include B-cell depletion therapies, agents targeting B-cell survival factors, blockade of T-cell co-stimulation and anticytokine therapies. Issues remain, however, regarding clinical trial design and outcome measures in SLE which need to be addressed to optimize translation of these promising therapies into clinical practice.


Via Krishan Maggon
Krishan Maggon 's curator insight, March 29, 2015 3:53 AM
ImmunotherapyVol. 7, No. 3, Pages 255-270 , DOI 10.2217/imt.14.118(doi:10.2217/imt.14.118)

 

 

ReviewProgress with the use of monoclonal antibodies for the treatment of systemic lupus erythematosusNatasha Jordan‡,1, Pamela MK Lutalo‡,1,2 & David P D’Cruz*,1*Author for correspondence: david.d'cruz@kcl.ac.uk
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March 28, 2015 8:33 AM
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Neuronal Na+/K+ ATPase is an autoantibody target in paraneoplastic neurologic syndrome. - PubMed - NCBI

Neuronal Na+/K+ ATPase is an autoantibody target in paraneoplastic neurologic syndrome. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Neurology. 2015 Mar 25. pii: 10.1212/WNL.0000000000001493. [Epub ahead of print]
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Scooped by Gilbert C FAURE
March 28, 2015 8:30 AM
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Comparison of Diagnostic Accuracy of Microscopy and Flow Cytometry in Evaluating N-Methyl-D-Aspartate Receptor Antibodies in Serum Using a Live Cell-Based Assay

Comparison of Diagnostic Accuracy of Microscopy and Flow Cytometry in Evaluating N-Methyl-D-Aspartate Receptor Antibodies in Serum Using a Live Cell-Based Assay | AUTOIMMUNITY | Scoop.it
by Melanie Ramberger, Patrick Peschl, Kathrin Schanda, Regina Irschick, Romana Höftberger, Florian Deisenhammer, Kevin Rostásy, Thomas Berger, Josep Dalmau, Markus Reindl N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune...
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April 11, 2015 9:51 AM
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NOVA View® automated digital IFA microscope receives FDA de novo clearance - Virtual Press Office (press release)

Virtual Press Office (press release) NOVA View® automated digital IFA microscope receives FDA de novo clearance Virtual Press Office (press release) SAN DIEGO, April 10, 2015 /PRNewswire/ -- Inova Diagnostics, the worldwide leader in autoimmune...
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April 8, 2015 1:25 PM
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Clinical presentation of human C1q deficiency: How much of a lupus? - PubMed - NCBI

Clinical presentation of human C1q deficiency: How much of a lupus? - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Mol Immunol. 2015 Apr 3. pii: S0161-5890(15)00105-4. doi: 10.1016/j.molimm.2015.03.007. [Epub ahead of print] REVIEW
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April 8, 2015 12:14 PM
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Clinical correlates of human leukocyte antigen-G (HLA-G) in systemic sclerosis - Favoino - Clinical & Experimental Immunology - Wiley Online Library

Clinical correlates of human leukocyte antigen-G (HLA-G) in systemic sclerosis - Favoino - Clinical & Experimental Immunology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Clinical correlates of human leukocyte antigenG (HLAG) in systemic sclerosis Clinical & Experimental Immunology http://t.co/P5ITzAnp8r
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Scooped by Gilbert C FAURE
April 4, 2015 4:26 PM
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Table of Contents — April 2015, 24 (4-5)

RT @cmftlibraries: Lupus, The Spectrum of Autoimmunity, guest edited by Yehuda Shoenfeld http://t.co/y3OVHclS9w http://t.co/YrPnJVs3gB @Lup…
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Scooped by Gilbert C FAURE
April 2, 2015 2:43 AM
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Infectious and Autoantibody-Associated Encephalitis: Clinical Features and Long-term Outcome

Infectious and Autoantibody-Associated Encephalitis: Clinical Features and Long-term Outcome | AUTOIMMUNITY | Scoop.it
Infectious and Autoantibody-Associated Encephalitis: Clinical Features and Long-term Outcome http://t.co/XwDv9mmA0F
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Scooped by Gilbert C FAURE
April 1, 2015 3:33 PM
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Scientists May Have Figured Out How To 'Switch Off' Autoimmune Disease

Scientists May Have Figured Out How To 'Switch Off' Autoimmune Disease | AUTOIMMUNITY | Scoop.it
A therapy used to treat allergies is now gaining wide acceptance in the fight against autoimmune diseases, as it teaches the immune response to correct itself, without any side effects.
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Scooped by Gilbert C FAURE
April 1, 2015 2:55 PM
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THE NICEGUIDELINES BLOG: Markedly disturbed immune signature in CSF with a shift towards a pattern associated with autoimmunity in ME/CFS

THE NICEGUIDELINES BLOG: Markedly disturbed immune signature in CSF with a shift towards a pattern associated with autoimmunity in ME/CFS | AUTOIMMUNITY | Scoop.it
Markedly disturbed immune signature in CSF with a shift towards a pattern associated with autoimmunity in #MEcfs http://t.co/xVMiMy8jai #cfs
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Scooped by Gilbert C FAURE
March 31, 2015 2:03 PM
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Therapeutics to block autoantibody initiation a...

Therapeutics to block autoantibody initiation a... | AUTOIMMUNITY | Scoop.it
AbstractMost current therapies for the autoimmune diseases systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), as well as many of the drugs in the therapeutic pipeline, reduce the autoimmune inflammatory process but lead to a general...
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Suggested by Société Francaise d'Immunologie
March 31, 2015 7:25 AM
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Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects

Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects | AUTOIMMUNITY | Scoop.it
Regulatory vs. Inflammatory Cytokine T-Cell Responses to Mutated Insulin Peptides in #T1D @PNASNews #OA http://t.co/dgJjN1phNF
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Scooped by Gilbert C FAURE
March 29, 2015 1:24 PM
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Extractable Nuclear Antigen Antibodies Panel Blood Test

Extractable Nuclear Antigen Antibodies Panel Blood Test | AUTOIMMUNITY | Scoop.it
Facts about Extractable Nuclear Antigen Antibodies Panel Blood Test, why is the laboratory test performed, specimen
collection, significance of results, use in diagnosis of medical conditions
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Scooped by Gilbert C FAURE
March 29, 2015 5:31 AM
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Platelets and the complement cascade in atherosclerosis. - PubMed - NCBI

Front Physiol. 2015 Mar 2;6:49. doi: 10.3389/fphys.2015.00049. eCollection 2015. Review
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Scooped by Gilbert C FAURE
March 28, 2015 8:31 AM
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Innate Immunity Drives the Initiation of a Murine Model of Primary Biliary Cirrhosis

Innate Immunity Drives the Initiation of a Murine Model of Primary Biliary Cirrhosis | AUTOIMMUNITY | Scoop.it
by Chao-Hsuan Chang, Ying-Chun Chen, Weici Zhang, Patrick S. C. Leung, M.
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