AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
April 23, 2015 12:24 PM
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Review: cancer-induced autoimmunity in the rheumatic diseases. - PubMed - NCBI

Review: cancer-induced autoimmunity in the rheumatic diseases. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Arthritis Rheumatol. 2015 Feb;67(2):317-26. doi: 10.1002/art.38928. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
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Scooped by Gilbert C FAURE
April 23, 2015 7:15 AM
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Oral Insulin and Immune Responses in Children at Risk for Diabetes

Oral Insulin and Immune Responses in Children at Risk for Diabetes | AUTOIMMUNITY | Scoop.it
This trial reports immune responses to insulin among children at risk for type 1 diabetes randomized to oral insulin vs placebo in an attempt to increase immune tolerance.
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Scooped by Gilbert C FAURE
April 22, 2015 5:34 AM
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Fine mapping in the MHC region accounts for 18% additional genetic risk for ... - Nature.com

Nature.com
Fine mapping in the MHC region accounts for 18% additional genetic risk for ...
Gilbert C FAURE's insight:

celiac disease

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Scooped by Gilbert C FAURE
April 18, 2015 3:54 PM
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Anti-Yo Antibody Uptake and Interaction with Its Intracellular Target Antigen Causes Purkinje Cell Death in Rat Cerebellar Slice Cultures: A Possible Mechanism for Paraneoplastic Cerebellar Degener...

Anti-Yo Antibody Uptake and Interaction with Its Intracellular Target Antigen Causes Purkinje Cell Death in Rat Cerebellar Slice Cultures: A Possible Mechanism for Paraneoplastic Cerebellar Degener... | AUTOIMMUNITY | Scoop.it
by John E. Greenlee, Susan A. Clawson, Kenneth E. Hill, Blair Wood, Stacey L. Clardy, Ikuo Tsunoda, Noel G. Carlson
Anti-Yo antibodies are immunoglobulin G (IgG) autoantibodies reactive with a 62 kDa Purkinje cell cytoplasmic protein.
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Scooped by Gilbert C FAURE
April 17, 2015 3:41 PM
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BMC Medicine | Full text | Unraveling the Hygiene Hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications

BMC Medicine | Full text | Unraveling the Hygiene Hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications | AUTOIMMUNITY | Scoop.it
The Hygiene Hypothesis (HH) attributes the dramatic increase in autoimmune and allergic diseases observed in recent decades in Western countries to the reduced exposure to diverse immunoregulatory infectious agents.
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Scooped by Gilbert C FAURE
April 17, 2015 7:14 AM
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The Real Target Of Miscarriage & Thrombosis Autoantibodies - Asian Scientist Magazine

The Real Target Of Miscarriage & Thrombosis Autoantibodies - Asian Scientist Magazine | AUTOIMMUNITY | Scoop.it
Over 80 percent of patients with antiphospholipid syndrome have autoantibodies against β2GPI in complex with HLA II.
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Scooped by Gilbert C FAURE
April 15, 2015 2:50 PM
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Caspase-1-Independent IL-1 Release Mediates Blister Formation in Au... - PubMed - NCBI

J Immunol. 2015 Mar 20. pii: 1402688. [Epub ahead of print]
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Rescooped by Gilbert C FAURE from Autoimmune diseases (Lupus, RA), Vaccines and Stem Cell Therapies Highlights
April 15, 2015 2:16 PM
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Editorial: Autoimmunity to Vimentin and Lupus Nephritis - Davidson - 2014 - Arthritis & Rheumatology - Wiley Online Library

Editorial: Autoimmunity to Vimentin and Lupus Nephritis - Davidson - 2014 - Arthritis & Rheumatology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
RT @SandraBlythe: Editorial: Autoimmunity to Vimentin and Lupus Nephritis http://t.co/nyprFeEtRE

Via Krishan Maggon
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Scooped by Gilbert C FAURE
April 14, 2015 2:12 PM
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Complex of GM1- and GD1a-Like Lipo-Oligosaccharide Mimics GM1b, Inducing Anti-GM1b Antibodies

Complex of GM1- and GD1a-Like Lipo-Oligosaccharide Mimics GM1b, Inducing Anti-GM1b Antibodies | AUTOIMMUNITY | Scoop.it
by Michiaki Koga, Michel Gilbert, Jianjun Li, Nobuhiro Yuki Objective Molecular mimicry between Campylobacter jejuni lipo-oligosaccharides (LOSs) and human gangliosides GM1 and GD1a induces the production of anti-GM1 and anti-GD1a antibodies, and...
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Suggested by Société Francaise d'Immunologie
April 14, 2015 2:09 PM
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Caspase-1-Independent IL-1 Release Mediates Blister Formation in Autoantibody-Induced Tissue Injury through Modulation of Endothelial Adhesion Molecules [AUTOIMMUNITY]

Although reports documented aberrant cytokine expression in autoimmune bullous dermatoses (AIBDs), cytokine-targeting therapies have not been established in these disorders.
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Scooped by Gilbert C FAURE
April 13, 2015 1:40 PM
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Islet autoantibody status in a multi-ethnic UK clinic cohort of children presenting with diabetes -- Perchard et al. 100 (4): 348 -- Archives of Disease in Childhood

Islet autoantibody status in a multi-ethnic UK clinic cohort of children presenting with diabetes http://t.co/7sW1pKQTqj
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Scooped by Gilbert C FAURE
April 12, 2015 3:39 PM
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B cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody production. - PubMed - NCBI

B cells take the front seat: dysregulated B cell signals orchestrate loss of tolerance and autoantibody production. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Curr Opin Immunol. 2015 Feb 10;33C:70-77. doi: 10.1016/j.coi.2015.01.018. [Epub ahead of print] REVIEW
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Scooped by Gilbert C FAURE
April 12, 2015 3:36 PM
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Swedish scientists find new markers for type 1 diabetes - Fox News

Swedish scientists find new markers for type 1 diabetes - Fox News | AUTOIMMUNITY | Scoop.it
Doctors may be able to detect type 1 diabetes in children before they exhibit any symptoms of the disease, new research from Sweden shows.
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Scooped by Gilbert C FAURE
April 23, 2015 7:16 AM
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Peritoneal cavity is a route for gut-derived microbial signals to promote autoimmunity in non-obese diabetic mice. - PubMed - NCBI

Peritoneal cavity is a route for gut-derived microbial signals to promote autoimmunity in non-obese diabetic mice. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Scand J Immunol. 2015 Feb;81(2):102-9. doi: 10.1111/sji.12253. Research Support, Non-U.S. Gov't
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Scooped by Gilbert C FAURE
April 23, 2015 7:14 AM
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JCI - Mechanisms of human autoimmunity

JCI - Mechanisms of human autoimmunity | AUTOIMMUNITY | Scoop.it
Mechanisms of human autoimmunity http://t.co/acwZMiFg51
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Scooped by Gilbert C FAURE
April 21, 2015 2:19 PM
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Latest genome sequencing techniques help identify new autoimmune syndrome in children

Latest genome sequencing techniques help identify new autoimmune syndrome in children | AUTOIMMUNITY | Scoop.it
Using the latest genome sequencing techniques, a research team led by scientists from UC San Francisco, Baylor College of Medicine, and Texas Children's Hospital has identified a new autoimmune syndrome characterized by a combination of severe lung...
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Suggested by Société Francaise d'Immunologie
April 18, 2015 3:53 PM
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Epigenetic Downregulation of SFRP4 Contributes to Epidermal Hyperplasia in Psoriasis [AUTOIMMUNITY]

Psoriasis is a chronic recurrent inflammatory skin disorder characterized by the dysregulated cross-talk between epidermal keratinocytes and immune cells, leading to keratinocyte hyperproliferation.
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Scooped by Gilbert C FAURE
April 17, 2015 7:25 AM
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Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy : Nature Communications : Nature Publishing Group

Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy : Nature Communications : Nature Publishing Group | AUTOIMMUNITY | Scoop.it
Anti #Autoimmune Disease injections moving to clinical trials! Self-antigen injections build tolerance.
http://t.co/VOlu6uWldb
#Autoimmunity
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Scooped by Gilbert C FAURE
April 16, 2015 2:35 PM
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The clinical features of autoimmunity in 53 patients with Wiskott–Aldrich syndrome in China: a single-center study - Online First - Springer

The clinical features of autoimmunity in 53 patients with Wiskott–Aldrich syndrome in China: a single-center study - Online First - Springer | AUTOIMMUNITY | Scoop.it
The clinical features of autoimmunity in 53 patients with Wiskott–Aldrich syndrome in China: a single-center s... http://t.co/Ss7bfLKfjN
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Scooped by Gilbert C FAURE
April 15, 2015 2:50 PM
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Serum DHCR24 auto-antibody as a new biomarker for progression of hepatitis C

RT @EBioMedicine: Serum #DHCR24 #autoantibody as a new #biomarker for progression of #hepatitis C http://t.co/u2OkJN8o8n http://t.co/LblRVK…
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Scooped by Gilbert C FAURE
April 14, 2015 2:13 PM
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Israeli Researcher Rebrands Sleep Disorder Narcolepsy As 'Autoimmune ... - NoCamels - Israeli Innovation News (press release) (blog)

Israeli Researcher Rebrands Sleep Disorder Narcolepsy As 'Autoimmune ... - NoCamels - Israeli Innovation News (press release) (blog) | AUTOIMMUNITY | Scoop.it
Nacroleptics suffer from sleep "attacks", impairing daily life. Israeli research now sheds light on the reason behind this illusive disease.
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Suggested by Société Francaise d'Immunologie
April 14, 2015 2:09 PM
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IgM and IgA Rheumatoid Factors Purified from Rheumatoid Arthritis Sera Boost the Fc Receptor- and Complement-Dependent Effector Functions of the Disease-Specific Anti-Citrullinated Protein Autoanti...

Rheumatoid factors (RF) and the disease-specific anti–citrullinated protein autoantibodies (ACPA) coexist in the joints of rheumatoid arthritis (RA) patients where they probably contribute to synovitis.
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Scooped by Gilbert C FAURE
April 14, 2015 1:53 PM
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NOVA View® automated digital IFA microscope receives FDA de novo clearance - PR Newswire (press release)

NOVA View® automated digital IFA microscope receives FDA de novo clearance - PR Newswire (press release) | AUTOIMMUNITY | Scoop.it
SAN DIEGO, April 10, 2015 /PRNewswire/ -- Inova Diagnostics, the worldwide leader in autoimmune diagnostic...
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Scooped by Gilbert C FAURE
April 13, 2015 1:02 PM
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Inova Diagnostics gains FDA de novo clearance for NOVA View automated ... - News-Medical.net

Inova Diagnostics gains FDA de novo clearance for NOVA View automated ... - News-Medical.net | AUTOIMMUNITY | Scoop.it
Inova Diagnostics, the worldwide leader in autoimmune diagnostic reagents and systems for the clinical laboratory, announced today that the United States Food and Drug Administration has cleared NOVA View, an automated digital IFA (indirect...
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Scooped by Gilbert C FAURE
April 12, 2015 3:38 PM
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Virus-induced preferential antibody gene-usage and its importance in humoral autoimmunity. - PubMed - NCBI

Virus-induced preferential antibody gene-usage and its importance in humoral autoimmunity. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Semin Immunol. 2015 Apr 6. pii: S1044-5323(15)00016-0. doi: 10.1016/j.smim.2015.03.008. [Epub ahead of print] REVIEW
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