In a pilot study that included children at high risk for type 1 diabetes, daily high-dose oral insulin, compared with placebo, resulted in an immune response to insulin without hypoglycemia, findings that support the need for a phase 3 trial to...
Autoimmune disorders (AID) have been increasingly observed in association with monogenic primary immunodeficiencies (PID). Here we discuss the interface between PID and AID, focus...
Exciting talk bringing Big Data and autoimmunity together at the Cambridge HealthTech Institute's Bio-IT World Conference and Expo. April 21-23, Boston.
In a pilot study described in the latest issue of JAMA, daily treatment with a highdose oral insulin in children at high risk for type 1 diabetes led to an immune response to insulin without hypoglycemia.
Nature.com Homeostatic regulation of T cell trafficking by a B cell–derived peptide is ... Nature.com Expression of adiponectin receptors on B cells and adiponectin-induced PEPITEM secretion wanes with age, implying immune senescence of the pathway.
Researchers from the Yale Cancer Center and the Veterans Affairs Greater Los Angeles Healthcare System have devised a way to re-engineer lupus antibodies to turn them into potential cancer killers.
Human leukocyte antigen polymorphisms and personalized medicine for ... Nature.com Many studies have reported that polymorphisms at the HLA-DRB1 locus are associated with several different autoimmune diseases including RA.
Celiac disease is one of the most common life-long conditions in Europe, yet many people remain undiagnosed and lengthy diagnostic delays may be putting lives at risk.
Autoantibodies to cellular constituents are the serological hallmark in systemic autoimmune rheumatic diseases 1. They are often associated with certain diagnosis, clinical features, or disease act...
Dr. Diane Kamen, of the Medical University of South Carolina, is investigating whether microbes in the gut are capable of contributing to the development of ...
Creation of U.S. subsidiary important strategic step for Neovacs in extending clinical initiatives for its lead product candidate, Lupus vaccine IFN-Kinoid
Here researchers report a new autoimmune disease, occurring in five families, that is characterized by interstitial lung disease and inflammatory arthritis and has as genetic cause mutations in COPA gene, a key component of vesicular trafficking...
Autoimmune Process Linked To Rejection Of Secondary Corneal Transplants ... Science 2.0 Researchers have identified an important cause of why secondary corneal transplants are rejected at triple the rate of first-time corneal transplants.
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