AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
September 13, 2013 1:58 PM
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A Study on Detection of Dickkopf-1 Autoantibody in Serums of ...

Background: lung cancer is the most common malignant tumor,Currently,there are many clinical methods to detect lung cancer,but these methods are not very perfect in diagnosis、treatment and prognosis of NSCLC.
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Scooped by Gilbert C FAURE
September 12, 2013 3:48 PM
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Virus Antibody Survey in Different European Populations Indicates ...

Abstract. Enteroviruses have been connected to type 1 diabetes in various studies. The current study evaluates the association between specific enterovirus subtypes and type 1 diabetes by measuring type-specific antibodies ...
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Scooped by Gilbert C FAURE
September 11, 2013 1:09 PM
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Islet autoimmunity in phenotypic type 2 diabetes patients

Islet autoimmunity in phenotypic type 2 diabetes patients | AUTOIMMUNITY | Scoop.it
Endocrinology Medical Article: Islet autoimmunity in phenotypic type 2 diabetes patients (Islet autoimmunity in phenotypic type 2 diabetes patients: Diabetes, Obesity and Metabolism http://t.co/exJPtQA2RQ...
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Rescooped by Gilbert C FAURE from Immunology
September 10, 2013 2:49 PM
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damsdelhi - Immunology update HLA and diseases Celiac... | Facebook

damsdelhi - Immunology update HLA and diseases Celiac... | Facebook | AUTOIMMUNITY | Scoop.it
Immunology update
HLA and diseases
Celiac disease DQ2
Ankylosing spondilytis B27
Narcolepsy: DQ6
sub acute thyroiditis: B35
type 1DM :DQ8
multiple...
Gilbert C FAURE's curator insight, September 10, 2013 2:48 PM

proving again how people everywhere are interpreting hla phenotyping and supporting that it should not be assayed for diagnosis!

Rescooped by Gilbert C FAURE from Mucosal Immunity
September 10, 2013 8:13 AM
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Prevalence of Celiac Disease Not Reflected in Diagnosis Rate - Gastroenterology & Endoscopy News

Prevalence of Celiac Disease Not Reflected in Diagnosis Rate - Gastroenterology & Endoscopy News | AUTOIMMUNITY | Scoop.it
Prevalence of Celiac Disease Not Reflected in Diagnosis Rate
Gastroenterology & Endoscopy News
“The fact of the matter is that most U.S.
Gilbert C FAURE's curator insight, September 10, 2013 8:13 AM

although in europe, many more assays prescribed than before, but not so many new diagnosis... Real epidemiological studies required.

Scooped by Gilbert C FAURE
September 9, 2013 1:54 PM
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Autoimmunity, seizures, and status epilepticus. [Epilepsia. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
September 7, 2013 3:03 PM
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Calcium-Sensing Receptor Autoantibodies and Idiopathic Hypoparathyroidism - Journal of Clinical Endocrinology and Metabolism

Calcium-Sensing Receptor Autoantibodies and Idiopathic Hypoparathyroidism
Journal of Clinical Endocrinology and Metabolism
Duration of illness and coexistent autoimmunity were similar in patients with and without CaSRAbs.
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Scooped by Gilbert C FAURE
September 6, 2013 3:40 PM
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A case with anti-galactocerebroside antibody-posi... [Neurol Sci. 2012] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
September 5, 2013 12:05 PM
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Alzheimer's may be linked to better hygiene, say scientists - The Guardian

Alzheimer's may be linked to better hygiene, say scientists - The Guardian | AUTOIMMUNITY | Scoop.it
The Guardian
Alzheimer's may be linked to better hygiene, say scientists
The Guardian
"Prevalence of autoimmunity varies between populations in accordance with variation in environmental microbial diversity.
Gilbert C FAURE's insight:

hypothesis on epidemiological data.. lacks still biological support

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Scooped by Gilbert C FAURE
September 4, 2013 3:22 PM
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Altered expression of the plasminogen activation pathway in peripheral blood mononuclear cells in multiple sclerosis: possible pathomechanism of matrix metalloproteinase activation

Altered expression of the plasminogen activation pathway in peripheral blood mononuclear cells in multiple ... - http://t.co/KMIyumyEKW
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Scooped by Gilbert C FAURE
September 4, 2013 11:06 AM
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Multiple Sclerosis Research: Autoantibody in spinal fluids

Multiple Sclerosis Research: Autoantibody in spinal fluids | AUTOIMMUNITY | Scoop.it
Hunting for antibodies in tissue fluids is a pass-time for immunologists. This study adds yet one more to the growing list, a bit of a light chain of antibodies, but as ever, this occurs in a minority of Mers so what is the real ...
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Scooped by Gilbert C FAURE
September 2, 2013 2:22 PM
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IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39 | AUTOIMMUNITY | Scoop.it
From BioPortfolio: The immunoregulatory effect of IL-27 is thought to act mainly on T cells. Quintana and colleagues show that IL-27 also converts conventional DCs into immunosupp...
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Scooped by Gilbert C FAURE
September 2, 2013 7:20 AM
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Updated estimate of AQP4-IgG serostatus and disability outcome in neuromyelitis optica

Updated estimate of AQP4-IgG serostatus and disability outcome in neuromyelitis optica | AUTOIMMUNITY | Scoop.it
RT @NatRevNeurol: Recombinant antigen-based assay improves detection of AQP4 antibodies in patients with NMO http://t.co/Nj6jUGuCz1 via @fe…
Gilbert C FAURE's insight:

neuroimmunology NMO

Gilbert C FAURE's curator insight, March 4, 2014 10:01 AM

Conclusions: Serological tests using recombinant AQP4 antigen are significantly more sensitive than tissue-based IIF for detecting AQP4-IgG. Testing should precede immunotherapy; if negative, later-drawn specimens should be tested. AQP4-IgG–seronegative NMO is less frequent than previously reported and is clinically similar to AQP4-IgG–seropositive NMO.

Scooped by Gilbert C FAURE
September 13, 2013 1:58 PM
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Involvement of autoimmunity to REG, a regeneration factor, in patients with primary Sjögren's syndrome - Yoshimoto - 2013 - Clinical & Experimental Immunology - Wiley Online Library

Involvement of autoimmunity to, a regeneration factor, in primary Sjögren's syn Yoshimoto 2013 http://t.co/y4n1FZWRaB
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Scooped by Gilbert C FAURE
September 12, 2013 8:17 AM
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Brief Report: Antibodies Reacting to Bra... [J Autism Dev Disord. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
September 11, 2013 12:50 PM
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Antibodies determined cancer risk in dermatomyositis patients - Healio

Antibodies determined cancer risk in dermatomyositis patients - Healio | AUTOIMMUNITY | Scoop.it
Antibodies determined cancer risk in dermatomyositis patients Healio Testing sera in patients with dermatomyositis determined that antibodies to anti-transcriptional intermediary factor-1 and nuclear matrix protein NXP-2 were present in most...
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Scooped by Gilbert C FAURE
September 10, 2013 2:13 PM
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Distinction and Temporal Stability of Conformational Epitopes on Myelin Oligodendrocyte Glycoprotein Recognized by Patients with Different Inflammatory Central Nervous System Diseases

Distinction and Temporal Stability of Conformational Epitopes on Myelin Oligodendrocyte Glycoprotein Recognized by Patients with Different Inflammatory Central Nervous System Diseases | AUTOIMMUNITY | Scoop.it
Paper: Distinction and Temporal Stability of Conformational MOG Epitopes Recognized by Patients. J. Immunology 2013 http://t.co/ytVN3NK3kG
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Scooped by Gilbert C FAURE
September 9, 2013 1:55 PM
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Top 10 clinical research developments in antiphospholipid syndrome

Top 10 clinical research developments in antiphospholipid syndrome | AUTOIMMUNITY | Scoop.it
Rheumatology Medical Article: Top 10 clinical research developments in antiphospholipid syndrome (Top 10 clinical research developments in antiphospholipid syndrome: Current Rheumatology Reports http://t.co/YhLKaxjBBI...
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Scooped by Gilbert C FAURE
September 8, 2013 3:57 AM
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Is Autoimmunity or Insulin Resistance the Prim... [Curr Diab Rep. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:

still no clear answer

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Scooped by Gilbert C FAURE
September 7, 2013 2:56 AM
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Lack of adiponectin leads to increased lymphocyte activation and ...

Lack of adiponectin leads to increased lymphocyte activation and ... | AUTOIMMUNITY | Scoop.it
Piccio L, Cantoni C, Henderson JG, Hawiger D, Ramsbottom M, Mikesell R, Ryu J, Hsieh CS, Cremasco V, Haynes W, Dong LQ, Chan L, Galimberti D, Cross AH; (2013) European Journal of Immunology, 43 (8), pp.
Gilbert C FAURE's insight:

multiple sclerosis mouse model

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Scooped by Gilbert C FAURE
September 6, 2013 7:38 AM
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GABAB receptor autoantibody frequency in service serologic evaluation

GABAB receptor autoantibody frequency in service serologic evaluation | AUTOIMMUNITY | Scoop.it
RT @GreenJournal: GABAB receptor autoantibody frequency in service serologic evaluation
http://t.co/Wyd9qA1OEp #Neurology http://t.co/GPf…;
Gilbert C FAURE's curator insight, March 4, 2014 10:02 AM

Conclusion: GABABR autoantibody is a marker of an uncommon but treatable paraneoplastic neurologic disorder, usually occurring in the setting of limbic encephalitis and SCLC.

Scooped by Gilbert C FAURE
September 5, 2013 12:03 PM
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Head trauma linked to slight increase in celiac disease risk - Healio

Head trauma linked to slight increase in celiac disease risk - Healio | AUTOIMMUNITY | Scoop.it
Head trauma linked to slight increase in celiac disease risk Healio “We hypothesized that head trauma and secondary cerebral and cerebellar insult may trigger autoimmunity against TG6, which in turn may lead, in genetically susceptible individuals,...
Gilbert C FAURE's insight:

very low increased risk in this large retrospective study? is it significant ??

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Scooped by Gilbert C FAURE
September 4, 2013 3:18 PM
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BMC Medicine | Full text | What is next after the genes for autoimmunity?

Clinical pathologies draw us to envisage disease as either an independent entity or a diverse set of traits governed by common physiopathological mechanisms, prompted by environmental assaults throughout life.
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Scooped by Gilbert C FAURE
September 3, 2013 3:08 PM
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The FMS-like tyrosine kinase 3-ligand may be biological marker of lymphoma in primary Sjogrens syndrome

The FMS-like tyrosine kinase 3-ligand may be biological marker of lymphoma in primary Sjogrens syndrome | AUTOIMMUNITY | Scoop.it
Rheumatology Medical Article: The FMS-like tyrosine kinase 3-ligand may be biological marker of lymphoma in primary Sjogrens syndrome (The FMS-like tyrosine kinase 3-ligand may be biological marker of lymphoma in primary Sjogrens s...
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Scooped by Gilbert C FAURE
September 2, 2013 2:20 PM
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Interferon-gamma and Systemic Autoimmunity - Kenneth M Pollard ...

Interferon-gamma and Systemic Autoimmunity - Kenneth M Pollard ... | AUTOIMMUNITY | Scoop.it
The term interferon describes a family of proteins consisting of three major types (I, II, and III) which differ in their primary protein sequences, cognate receptors, genetic loci, and cell types responsible for their production.
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