AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
October 16, 2013 2:09 PM
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Inhibiting a single protein could improve the treatment of atherosclerosis - Medical Xpress

Inhibiting a single protein could improve the treatment of atherosclerosis - Medical Xpress | AUTOIMMUNITY | Scoop.it
Inhibiting a single protein could improve the treatment of atherosclerosis Medical Xpress The results of their study, published in the prestigious journal EMBO Molecular Medicine, suggest that Rcan1 is a potential target for future drug treatments...
Gilbert C FAURE's comment, October 16, 2013 2:18 PM
more inflammation than autoimmunity, but interesting
Scooped by Gilbert C FAURE
October 15, 2013 5:09 AM
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What Every American Needs to Know About Autoimmune Disease - Newswise (press release)

What Every American Needs to Know About Autoimmune Disease
Newswise (press release)
Newswise — A National autoimmune disease multi-city conference tour arrives in Charleston, SC on Saturday, November 2, 2013.
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Scooped by Gilbert C FAURE
October 12, 2013 3:09 PM
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Getting Under the Skin of Scleroderma - Howard Hughes Medical Institute

Getting Under the Skin of Scleroderma - Howard Hughes Medical Institute | AUTOIMMUNITY | Scoop.it
Getting Under the Skin of Scleroderma
Howard Hughes Medical Institute
To see if they could stop the observed cascade of events, Dietz's group turned to an antibody that promotes the interaction between integrins and their matrix-binding partners.
Gilbert C FAURE's insight:

mouse model of scleroderma

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Scooped by Gilbert C FAURE
October 11, 2013 10:06 AM
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Expert Review of Clinical Immunology - Vol. 7

See ER of Clinical Immunology's previous special focus issue for more information on #SystemicSclerosis http://t.co/CwK2HtcMzB
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Scooped by Gilbert C FAURE
October 11, 2013 5:52 AM
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Frontiers | MHC Class II Polymorphisms, Autoreactive T-Cells, and Autoimmunity | Frontiers in Antigen Presenting Cell Biology

Major histocompatibility complex (MHC) genes, also known as human leukocyte antigen genes (HLA) in humans, are the prevailing contributors of genetic susceptibility to autoimmune diseases such as Type 1 Diabetes (T1D), Multiple Sclerosis (MS), and...
Gilbert C FAURE's insight:

... This review provides an update on current advances in our understanding of the mechanisms underlying MHC class II-associated autoimmune disease susceptibility and/or resistance and attempts to reconcile these seemingly opposing concepts.

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Scooped by Gilbert C FAURE
October 9, 2013 2:17 PM
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IgM Antibody Identifies Good Candidates for Natalizumab - Medscape

IgM Antibody Identifies Good Candidates for Natalizumab Medscape COPENHAGEN, Denmark — Researchers in Spain have identified lipid-specific antibody bands in the cerebrospinal fluid (CSF) that are associated with an aggressive presentation of...
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Scooped by Gilbert C FAURE
October 8, 2013 1:42 PM
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Frontiers | Antigen mimicry between infectious agents and self or environmental antigens may lead to long-term regulation of inflammation | Frontiers in Microbial Immunology

Antigen mimicry between infectious agents and self or environmental antigens may lead to long-term regulation of inflammation (Antigen mimicry between infectious agents and self or environmental antigens may lead to long-term...
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Scooped by Gilbert C FAURE
October 7, 2013 1:45 PM
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Frontiers | Nucleic Acid Sensors and Type I Interferon Production in Systemic Lupus Erythematosus | Frontiers in Molecular Innate Immunity

The characteristic serologic feature of systemic lupus erythematosus (SLE) is autoantibodies against one’s own nucleic acid or nucleic acid-binding proteins - DNA and RNA-binding nuclear proteins.
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Scooped by Gilbert C FAURE
October 7, 2013 1:37 PM
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Top Speakers | Autoimmunity Congress 2014 | Professor Yehuda Shoenfeld

The 9th International Congress on Autoimmunity which will be held in Nice, France from March 26-30, 2014, will build on the success of previous congresses wi...
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Scooped by Gilbert C FAURE
October 5, 2013 2:35 PM
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Autoantibody prevalence with an improved i... [Clin Chem Lab Med. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
October 5, 2013 2:46 AM
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The Michael J. Fox Foundation Funds Research to Develop Parkinson's Blood Test - PR Newswire (press release)

The Michael J. Fox Foundation Funds Research to Develop Parkinson's Blood Test PR Newswire (press release) In a pilot study published last year, the test was remarkably accurate (93.1 percent sensitivity and 100 percent specificity) in detecting...
Gilbert C FAURE's insight:

which autoantibody?

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Scooped by Gilbert C FAURE
October 5, 2013 2:44 AM
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News and Reviews - Journal of Clinical Endocrinology and Metabolism

News and Reviews Journal of Clinical Endocrinology and Metabolism AN AUTOANTIBODY RISK SCORE (ABRS), incorporating levels of multiple islet autoantibodies, was strongly predictive of type 1 diabetes and was even more accurate when combined with the...
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Scooped by Gilbert C FAURE
October 3, 2013 3:06 PM
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Clinical Relevance of Autoantibody Detection in Lung Cancer : Journal of Thoracic Oncology

Clinical Relevance of Autoantibody Detection in Lung Cancer : Journal of Thoracic Oncology | AUTOIMMUNITY | Scoop.it
Sensitive techniques have recently been developed to identify tumoral antigens and to detect tumor-related autoantibodies in the peripheral blood of patients with cancer.
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Scooped by Gilbert C FAURE
October 15, 2013 2:29 PM
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Circulating Anti-Beta2-Glycoprotein I Antibodies Are Associated with ...

Circulating Anti-Beta2-Glycoprotein I Antibodies Are Associated with ... | AUTOIMMUNITY | Scoop.it
These autoantibodies are directed against beta2-glycoprotein antigens, a plasmatic protein that displays an intense tropism for endothelial cell membrane phospholipids [10, 15–17]. Circulating ABGPI activity involves dendritic cells activation ...
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Scooped by Gilbert C FAURE
October 14, 2013 1:54 PM
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Immunotherapy Helps ID Epilepsy Type - MedPage Today

Immunotherapy Helps ID Epilepsy Type - MedPage Today | AUTOIMMUNITY | Scoop.it
Immunotherapy Helps ID Epilepsy Type MedPage Today Among them were 29 with medically intractable seizures as the exclusive or dominant complaint, with an autoimmune cause suspected because of inflammatory markers in cerebrospinal fluid, MRI scan...
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Scooped by Gilbert C FAURE
October 12, 2013 7:18 AM
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Tight Junctions, Intestinal Permeability, and Autoimmunity Celiac Disease and Type 1 Diabetes Paradigms

Tight junctions, intestinal permeability, and autoimmunity celiac disease and type 1 diabetes paradigms. http://t.co/g3RJUGAG87
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Scooped by Gilbert C FAURE
October 11, 2013 5:52 AM
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E-cadherin autoantibody profile in patients with pemphigus vulgaris - Oliveira - 2013 - British Journal of Dermatology - Wiley Online Library

E-cadherin autoantibody profile in patients with pemphigus vulgaris - Oliveira - 2013 - British Journal of Dermatology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Ecadherin autoantibody profile in patients with pemphigus vulgaris Oliveira 2013 British Journal of Dermatology http://t.co/plKYQJuhgQ
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Scooped by Gilbert C FAURE
October 10, 2013 4:01 AM
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Lupus Research Institute Announces New Global Research on Fundamental ... - Sacramento Bee

Lupus Research Institute Announces New Global Research on Fundamental ... - Sacramento Bee | AUTOIMMUNITY | Scoop.it
Lupus Research Institute Announces New Global Research on Fundamental ...
Sacramento Bee
Dr. Tarlinton will explore new ways to kill the cells responsible for producing autoantibodies that damage tissue and organs in lupus.
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Scooped by Gilbert C FAURE
October 9, 2013 1:58 PM
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Compugen Drug Candidate Demonstrates High Effectiveness in Type I Diabetes ... - Wall Street Journal

Compugen Drug Candidate Demonstrates High Effectiveness in Type I Diabetes ... - Wall Street Journal | AUTOIMMUNITY | Scoop.it
Compugen Drug Candidate Demonstrates High Effectiveness in Type I Diabetes ...
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Scooped by Gilbert C FAURE
October 8, 2013 1:42 PM
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In Brief: Autoimmunity and ME

In Brief: Autoimmunity and ME | AUTOIMMUNITY | Scoop.it
The second in series of short articles attempting to explain the science behind fairly common topics and exploring how they relate to ME. This time the topic is Autoimmunity – by Andrew Gladman.
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Scooped by Gilbert C FAURE
October 7, 2013 1:44 PM
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Multiple Checkpoint Breach of B Cell Tolerance in Rasgrp1 ...

Multiple Checkpoint Breach of B Cell Tolerance in Rasgrp1 ... | AUTOIMMUNITY | Scoop.it
Address correspondence and reprint requests to Dr. Robert A. Barrington, Department of Microbiology and Immunology, University of South Alabama, MSB 2114, 5851 USA Drive North, Room 2114, Mobile, AL 36604.
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Scooped by Gilbert C FAURE
October 6, 2013 2:16 PM
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Trends in Immunology - Immune mechanisms in type 1 diabetes

RT @ImmunityCP: TrendsImmunol: Wallberg and Cooke examine the immune basis of type 1 #diabetes http://t.co/KDmtmppuCA
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Scooped by Gilbert C FAURE
October 5, 2013 2:33 PM
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EMD Serono Makes First Awards as Part of the Company's 1 Million Euro Grant ... - DigitalJournal.com

EMD Serono Makes First Awards as Part of the Company's 1 Million Euro Grant ...
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Scooped by Gilbert C FAURE
October 5, 2013 2:45 AM
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Isolated Prolactin Deficiency Associated With Serum Autoantibodies Against ... - Journal of Clinical Endocrinology and Metabolism

Isolated Prolactin Deficiency Associated With Serum Autoantibodies Against ...
Journal of Clinical Endocrinology and Metabolism
Design and Setting: We examined genetic and autoimmune causes of isolated PRL deficiency at academic medical centers.
Gilbert C FAURE's insight:

a documented case report of rare disease

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Scooped by Gilbert C FAURE
October 4, 2013 6:39 AM
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A $1000000 Gift to Fund the Artech Autoimmune Cell Re-Education Study - ParamusPost.com

A $1000000 Gift to Fund the Artech Autoimmune Cell Re-Education Study - ParamusPost.com | AUTOIMMUNITY | Scoop.it
A $1000000 Gift to Fund the Artech Autoimmune Cell Re-Education Study
ParamusPost.com
The HackensackUMC Foundation has received a $1,000,000 pledge to fund the Artech Autoimmune Cell Re-Education Study at HackensackUMC.
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