AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
October 30, 2013 2:24 PM
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Associate Professor Andrew Lew | Walter and Eliza Hall Institute of Medical Research

Associate Professor Andrew Lew | Walter and Eliza Hall Institute of Medical Research | AUTOIMMUNITY | Scoop.it
The Walter and Eliza Hall Institute (WEHI) was the first medical research institute to be established in Australia.
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Scooped by Gilbert C FAURE
October 29, 2013 11:47 AM
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Antibodies | Free Full-Text | Regulation of Germinal Center ...

Although the function of TFH cells is beneficial in generating high affinity antibodies against infectious agents, aberrant activation of TFH cell or B cell to self-antigens results in autoimmunity. At least three subsets of immune ...
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Scooped by Gilbert C FAURE
October 28, 2013 2:29 PM
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Prevalence of anti-RNA polymerase III antibodies in systemic sclerosis: New data from a French cohort, systematic review and meta-analysis

Prevalence of anti-RNA polymerase III antibodies in systemic sclerosis: New data from a French cohort, systematic review and meta-analysis | AUTOIMMUNITY | Scoop.it
Rheumatology Medical Article: Prevalence of anti-RNA polymerase III antibodies in systemic sclerosis: New data from a French cohort, systematic review and meta-analysis (#scleroderma I just have added an exclusive commentary on our manuscript on anti...
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Scooped by Gilbert C FAURE
October 26, 2013 5:04 AM
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Epratuzumab's Mechanism of Action Featured in Blood, Official Journal of The ... - HispanicBusiness.com

Epratuzumab's Mechanism of Action Featured in Blood, Official Journal of The ...
HispanicBusiness.com
MORRIS PLAINS, N.J. , Oct. 25, 2013 (GLOBE NEWSWIRE) -- Immunomedics, Inc.
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Scooped by Gilbert C FAURE
October 24, 2013 9:32 AM
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Autoimmunity Conference - Nice, France | 26-30 March, 2014

Autoimmunity Conference - Nice, France | 26-30 March, 2014 | AUTOIMMUNITY | Scoop.it
The 9th International Congress on Autoimmunity will take place in Nice, France, from 26-30 March, 2014.
Gilbert C FAURE's insight:

bis or ter

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Scooped by Gilbert C FAURE
October 22, 2013 2:00 PM
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Trends in Autoantibody Testing

Trends in Autoantibody Testing | AUTOIMMUNITY | Scoop.it
Webinar: Trends in Autoantibody Testing; 29/10; hora según origen 2:00 a 3:00pm (GMT -7). http://t.co/QNeDzj95LG
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Scooped by Gilbert C FAURE
October 22, 2013 1:59 PM
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T-bet or not T-bet: Taking the last bow on the autoimmunity stage - Spath - 2013 - European Journal of Immunology - Wiley Online Library

T-bet or not T-bet: Taking the last bow on the autoimmunity stage - Spath - 2013 - European Journal of Immunology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Psoriasis Info T‐bet or not T‐bet: Taking the last bow on the autoimmunity stage http://t.co/gZtiw81AYM
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Scooped by Gilbert C FAURE
October 18, 2013 2:53 PM
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UB Scientists ID First 'Protection Signature' for Autoimmune Disease - UB School of Medicine and Biomedical Sciences News

UB Scientists ID First 'Protection Signature' for Autoimmune Disease - UB School of Medicine and Biomedical Sciences News | AUTOIMMUNITY | Scoop.it
UB Scientists ID First 'Protection Signature' for Autoimmune Disease UB School of Medicine and Biomedical Sciences News “It may be possible to identify genes and immune pathways that can be manipulated in patients and at-risk individuals to prevent...
Gilbert C FAURE's insight:

pemphigus

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Scooped by Gilbert C FAURE
October 17, 2013 3:10 PM
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Neuropsychiatric systemic lupus erythematosus: Pathophysiology and the future of treatment

Neuropsychiatric systemic lupus erythematosus: Pathophysiology and the future of treatment | AUTOIMMUNITY | Scoop.it
Rheumatology Medical Article: Neuropsychiatric systemic lupus erythematosus: Pathophysiology and the future of treatment (RT @MDLinx: Neuropsychiatric systemic lupus erythematosus: Pathophysiology and the future of treatment: Inte...
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Scooped by Gilbert C FAURE
October 17, 2013 10:18 AM
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Compugen Presents Experimental Results Supporting Induction of Immune ... - PharmaLive (press release) (subscription)

Compugen Presents Experimental Results Supporting Induction of Immune ... - PharmaLive (press release) (subscription) | AUTOIMMUNITY | Scoop.it
Compugen Presents Experimental Results Supporting Induction of Immune ...
PharmaLive (press release) (subscription)
Establishment of immune tolerance is a key goal in the treatment of autoimmune diseases.
Gilbert C FAURE's insight:

an animal model study in which CGEN-15001, an Fc fusion protein drug candidate derived from a novel immune checkpoint protein discovered by Compugen, demonstrated potential to induce immune tolerance, a much desired goal for treatment of many immunological disorders.

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Scooped by Gilbert C FAURE
October 17, 2013 8:15 AM
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CD19 as a Therapeutic Target in a Spontaneous Autoimmune Polyneuropathy - Abraham - Clinical & Experimental Immunology - Wiley Online Library

CD19 as a Therapeutic Target in a Spontaneous Autoimmune Polyneuropathy - Abraham - Clinical & Experimental Immunology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
CD19 as a Therapeutic Target in a Spontaneous Autoimmune Polyneuropathy Abraham Clinical & Experimental Immunology http://t.co/i7Mr4cU74v
Gilbert C FAURE's insight:

therapeutic target!

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Scooped by Gilbert C FAURE
October 17, 2013 4:56 AM
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A Nationwide Study on the Risk of Autoimmune... [Am J Psychiatry. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:

Danish nationwide registers were linked to establish a cohort of 3.83 million people, identifying 39,364 individuals with schizophrenia-like psychosis and 142,328 individuals with autoimmune disease

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Scooped by Gilbert C FAURE
October 16, 2013 2:19 PM
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Antibody Test Spots IBS - MedPage Today

Antibody Test Spots IBS - MedPage Today | AUTOIMMUNITY | Scoop.it
Antibody Test Spots IBS MedPage Today Measurement of anti-vinculin antibodies in serum demonstrated higher levels of these autoantibodies in IBS patients, compared with those without the disorder, with positive predictive values between 90% and...
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Scooped by Gilbert C FAURE
October 29, 2013 3:32 PM
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Journal of Autoimmunity | Vol 46, Pgs 1-112, (October, 2013) | ScienceDirect.com

The online version of Journal of Autoimmunity at ScienceDirect.com, the world's leading platform for high quality peer-reviewed full-text journals.
Gilbert C FAURE's insight:

liver diseases and autoimmunity

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Scooped by Gilbert C FAURE
October 28, 2013 3:41 PM
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Anti-citrullinated peptide autoantibodies, human leukocyte antigen ...

The aim of this study was to characterize anti-citrullinated peptide antibody (ACPA) serostatus in pre-clinical rheumatoid arthritis (RA) with and without Human Leukocyte Antigen-Shared Eptiope (HLA-SE) alleles.
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Scooped by Gilbert C FAURE
October 28, 2013 8:32 AM
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Autoimmunity in Sisters of Lupus Patients

Autoimmunity in Sisters of Lupus Patients | AUTOIMMUNITY | Scoop.it
Clinical Trials - clinicaltrials.gov This study enrolled over 400 unaffected sisters of young women diagnosed with SLE. These unaffected sisters are being follo...
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Scooped by Gilbert C FAURE
October 25, 2013 7:52 AM
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PLOS ONE: Self-Organized Criticality Theory of Autoimmunity

PLOS ONE: Self-Organized Criticality Theory of Autoimmunity | AUTOIMMUNITY | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Scooped by Gilbert C FAURE
October 24, 2013 8:17 AM
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Dopamine Receptor Autoantibodies Correlate with Symptoms in Sydenham's Chorea

Dopamine Receptor Autoantibodies Correlate with Symptoms in Sydenham's Chorea | AUTOIMMUNITY | Scoop.it
Cunningham Paper Links Autoimmunity with #Neuropsychiatric Symptoms. http://t.co/pqefELUu2B #autoimmunity #mentalhealth #dopamine
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Scooped by Gilbert C FAURE
October 22, 2013 1:59 PM
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Frontiers | Programming of neuroendocrine self in the thymus and its defect in the development of neuroendocrine autoimmunity | Frontiers in Neuroendocrine Science

For centuries after its first description by Galen, the thymus was considered as only a vestigial endocrine organ until the discovery in 1961 by Jacques FAP Miller of its essential role in the development of T (thymo-dependent) lymphocytes.
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Scooped by Gilbert C FAURE
October 20, 2013 9:16 AM
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Islet-Specific T-Cell Responses and Proinflammatory Monocytes ...

A validated classification scheme for KPD includes two autoantibody-negative (“A−”) phenotypic forms: “A−β−” (lean, early onset, lacking β-cell functional reserve), and “A−β+” (obese, late onset, with substantial β-cell ...
Gilbert C FAURE's insight:

T cell responses coming into view

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Scooped by Gilbert C FAURE
October 18, 2013 8:40 AM
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Cellmid awarded Japanese patent for autoimmune disorder treatment with ... - Proactive Investors Australia

Cellmid awarded Japanese patent for autoimmune disorder treatment with ... - Proactive Investors Australia | AUTOIMMUNITY | Scoop.it
Cellmid awarded Japanese patent for autoimmune disorder treatment with ...
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Scooped by Gilbert C FAURE
October 17, 2013 3:00 PM
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Exome Sequencing Reveals RAG1 Mutations in a Child with Autoimmunity | Exome Sequencing

Exome Sequencing Reveals RAG1 Mutations in a Child with Autoimmunity | Exome Sequencing | AUTOIMMUNITY | Scoop.it
Researchers at USC describe a boy who developed autoinflammatory (chronic sterile multifocal osteomyelitis) and autoimmune (autoimmune cytopenias; vitiligo) (Exome Sequencing Reveals RAG1 Mutations in a Child with Autoimmunity -
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Scooped by Gilbert C FAURE
October 17, 2013 8:15 AM
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Myasthenia Gravis: An Update for the Clinician - Sieb - Clinical & Experimental Immunology - Wiley Online Library

Myasthenia Gravis: An Update for the Clinician - Sieb - Clinical & Experimental Immunology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Myasthenia Gravis: An Update for the Clinician Sieb Clinical & Experimental Immunology Wiley Online Library http://t.co/hU6glUEEwi
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Scooped by Gilbert C FAURE
October 17, 2013 8:14 AM
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Cerebral vasculitis in adults - What are the steps in order to establish the diagnosis? Red flags and pitfalls - Berlit - Clinical & Experimental Immunology - Wiley Online Library

Cerebral vasculitis in adults - What are the steps in order to establish the diagnosis? Red flags and pitfalls - Berlit - Clinical & Experimental Immunology - Wiley Online Library | AUTOIMMUNITY | Scoop.it
Cerebral vasculitis in adults ... Red flags and pitfalls Berlit Clinical & Experimental Immunology Wiley Online http://t.co/lzjmZG9wNV
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Scooped by Gilbert C FAURE
October 16, 2013 2:19 PM
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Sporadic colon cancer murine models demonstrate the value of autoantibody detection for preclinical cancer diagnosis : Scientific Reports : Nature Publishing Group

Sporadic colon cancer murine models demonstrate the value of autoantibody detection for preclinical cancer diagnosis : Scientific Reports : Nature Publishing Group | AUTOIMMUNITY | Scoop.it
Although autoantibody detection has been proposed for diagnosis of colorectal cancer, little is known about their initial production and development correlation with cancer progression.
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