AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
November 16, 2013 6:10 AM
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Autoantibody - Wikipedia, the free encyclopedia

Autoantibody

An autoantibody is an antibody (a type of protein) manufactured by the immune system that is directed against one or more of the individual's own proteins. Many autoimmune diseases, notably lupus erythematosus, are caused by such autoantibodies. Antibodies are produced by B cells in two ways: (i) randomly, and (ii) in response to a foreign protein or substance within the body.

Autoantibody - Wikipedia, the free encyclopedia http://t.co/i4aAcAPR9Q
Gilbert C FAURE's insight:

should have a look, and why not improve?

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Scooped by Gilbert C FAURE
November 15, 2013 3:15 PM
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Basis for fluctuations in lymphocyte counts in fingolimod-treated patients with multiple sclerosis

Basis for fluctuations in lymphocyte counts in fingolimod-treated patients with multiple sclerosis | AUTOIMMUNITY | Scoop.it
RT @GreenJournal: Basis for fluctuations in lymphocyte counts in fingolimod-treated patients with MS
http://t.co/QHzAbHjHWv #Neurology htt…
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Scooped by Gilbert C FAURE
November 15, 2013 3:12 PM
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Tregitope Europe at the 9th International Congress on Autoimmunity ...

Tregitope Europe at the 9th International Congress on Autoimmunity ... | AUTOIMMUNITY | Scoop.it
We are pleased to announce that EpiVax is hosting the “Tregitope Europe” meeting in conjunction with the 9th International Congress on Autoimmunity in Nice, France on March 26th 2014. The meeting will consist of a 120 ...
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Scooped by Gilbert C FAURE
November 15, 2013 8:31 AM
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A new category of Diabetes spreading fast in Odisha - The New Indian Express

A new category of Diabetes spreading fast in Odisha - The New Indian Express | AUTOIMMUNITY | Scoop.it
A new category of Diabetes spreading fast in Odisha The New Indian Express Called Type-1.5 (one and a half) or latent autoimmune disease in adults (LADA), the condition is being increasingly detected in patients perceived to be suffering from...
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diabetes in a global world

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Scooped by Gilbert C FAURE
November 14, 2013 9:59 AM
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Proteomic identification of aldolase A as an autoantibody target in patients with atypical movement disorders. - ncbi.nlm.nih.gov - BRIMS Reporter

Proteomic identification of aldolase A as an autoantibody target in patients with atypical movement disorders. - ncbi.nlm.nih.gov - BRIMS Reporter | AUTOIMMUNITY | Scoop.it
Proteomic identification of aldolase A as an autoantibody target in patients with atypical movement disorders. (Proteomic identification of aldolase A as an autoantibody target in patients with atypical movement d...
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Scooped by Gilbert C FAURE
November 9, 2013 3:31 AM
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FDA Reviewers Slam Lemtrada Efficacy, Safety - MedPage Today

FDA Reviewers Slam Lemtrada Efficacy, Safety - MedPage Today | AUTOIMMUNITY | Scoop.it
FDA Reviewers Slam Lemtrada Efficacy, Safety
MedPage Today
Alemtuzumab, a monoclonal antibody targeting the CD52 protein, is already well-known in the oncology field as a leukemia drug, sold for many years under the name Campath.
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Scooped by Gilbert C FAURE
November 8, 2013 1:01 PM
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Islet-specific T-cell responses and proinflammatory monocytes define subtypes of autoantibody-negative ketosis-prone diabetes (KPD)

Islet-specific T-cell responses and proinflammatory monocytes define subtypes of autoantibody-negative ketosis-prone diabetes (KPD) | AUTOIMMUNITY | Scoop.it
Endocrinology Medical Article: Islet-specific T-cell responses and proinflammatory monocytes define subtypes of autoantibody-negative ketosis-prone diabetes (KPD) (Islet-specific T-cell responses and proinflammatory monocytes define subtypes of...
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Scooped by Gilbert C FAURE
November 6, 2013 1:39 PM
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Autoantibodies may precede symptom onset in Sjögren’s Syndrome | 2 Minute Medicine

Autoantibodies may precede symptom onset in Sjögren’s Syndrome | 2 Minute Medicine | AUTOIMMUNITY | Scoop.it
Image: PD  1. 66% of patients with Sjögren’s Syndrome (SS) in this study had autoantibodies detected in the serum prior to symptom onset and diagnosis of SS.  2.
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Scooped by Gilbert C FAURE
November 6, 2013 11:01 AM
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Iodine Contributes to Thyroid Autoimmunity in Humans by Unmasking a Cryptic ... - Journal of Clinical Endocrinology and Metabolism

Iodine Contributes to Thyroid Autoimmunity in Humans by Unmasking a Cryptic ...
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Cryptic Epitope on Thyroglobulin
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Scooped by Gilbert C FAURE
November 6, 2013 11:00 AM
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Association Between Vitamin D Metabolism Gene Polymorphisms and Risk of ... - Journal of Clinical Endocrinology and Metabolism

Association Between Vitamin D Metabolism Gene Polymorphisms and Risk of ...
Gilbert C FAURE's insight:

diabetes type 1

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Scooped by Gilbert C FAURE
November 5, 2013 10:28 AM
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ORGENTEC Autoimmunity Blog

ORGENTEC Autoimmunity Blog | AUTOIMMUNITY | Scoop.it
Covering Autoimmune Diseases (Relaunch: Our #Autoimmunity Blog has been redesigned and has a new web address. Stay tuned!
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A blog on autoimmune diseases by a company developing in vitro assays.

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November 3, 2013 2:29 PM
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from Clin exp Immunol to paraneoplastic autoimmune syndroms

RT @Wiley_Health: Autumn highlights from Clinical & Experimental Immunology, the journal of translational immunology http://t.co/1iVaMGdhim
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Scooped by Gilbert C FAURE
October 31, 2013 4:58 PM
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Editorial: Btk—friend or foe in autoimmune diseases? - Journal of Leukocyte Biology (subscription)

Editorial: Btk—friend or foe in autoimmune diseases?
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Scooped by Gilbert C FAURE
November 15, 2013 3:20 PM
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Human Leukocyte Antigen Genetics and Clinical Features of Se... : Journal of Clinical Gastroenterology

Human Leukocyte Antigen Genetics and Clinical Features of Se... : Journal of Clinical Gastroenterology | AUTOIMMUNITY | Scoop.it
Background and Aims:Increasingly, people start a gluten-free diet (GFD) without a clear celiac disease (CD) diagnosis.
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Scooped by Gilbert C FAURE
November 15, 2013 3:13 PM
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Abstract | Transcriptional landscapes of emerging autoimmunity

Our understanding of autoimmunity is skewed considerably towards the late stages of overt disease and chronic inflammation. Defining the targeted organ's role during emergence of autoimmune diseases is, however, critical ...
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November 15, 2013 3:08 PM
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Clinical Science (2014) 126, 329-337 - S. O'Reilly - Innate immunity in systemic sclerosis pathogenesis

Clinical Science (2014) 126, 329-337 - S. O'Reilly - Innate immunity in systemic sclerosis pathogenesis | AUTOIMMUNITY | Scoop.it
Clinical Science is an international multi-disciplinary journal at the interface of clinical research and discovery science, publishing pre-clinical and clinical-based research addressing the biology of human health and disease.
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Scooped by Gilbert C FAURE
November 14, 2013 4:34 PM
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Children with celiac disease and high ... [World J Gastroenterol. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
November 12, 2013 2:31 PM
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Putting Lupus in permanent remission - Medical Xpress

Putting Lupus in permanent remission - Medical Xpress | AUTOIMMUNITY | Scoop.it
UPI.com
Putting Lupus in permanent remission
Medical Xpress
The study was published online in Clinical Immunology, the journal of the Federation of Clinical Immunology Societies.
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Scooped by Gilbert C FAURE
November 8, 2013 1:02 PM
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Defective stromal remodeling and neutrophil extracellular traps in lymphoid tissues favor the transition from autoimmunity to lymphoma

Defective stromal remodeling and neutrophil extracellular traps & transition from autoimmunity to lymphoma
http://t.co/eb8neeEGk5
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Scooped by Gilbert C FAURE
November 8, 2013 1:00 PM
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The Role of Epigenetics in Aging and Autoimmunity

The Role of Epigenetics in Aging and Autoimmunity
http://t.co/id8utOYcp6
Gilbert C FAURE's insight:

2010

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November 6, 2013 11:02 AM
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Autoantibodies found in blood years before symptom onset of autoimmune disease - Medical Xpress

Autoantibodies found in blood years before symptom onset of autoimmune disease - Medical Xpress | AUTOIMMUNITY | Scoop.it
Autoantibodies found in blood years before symptom onset of autoimmune disease Medical Xpress Autoantibodies are present many years before symptom onset in patients with primary Sjögren syndrome, an autoimmune disease, according to a Research...
Gilbert C FAURE's insight:

4 to 6 years before symptoms!!

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Scooped by Gilbert C FAURE
November 6, 2013 11:00 AM
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Potential Utility of Rituximab for Graves' Orbitopathy - Journal of Clinical Endocrinology and Metabolism

Potential Utility of Rituximab for Graves' Orbitopathy
Journal of Clinical Endocrinology and Metabolism
Context: B-Cell contribution to autoimmunity has been emphasized since the use of B-cell depleting therapies.
Gilbert C FAURE's insight:

some endocrinologists already used it...

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Scooped by Gilbert C FAURE
November 5, 2013 2:34 PM
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http://bmjopen.bmj.com/content/3/10/e003608.full

Missed It? Antinuclear antibody staining patterns and clinical features of Systemic Lupus Erythematosus: BMJ: http://t.co/ACD4DoYpwk
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Scooped by Gilbert C FAURE
November 3, 2013 2:37 PM
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Autoantibodies a Big Deal in Sjogren's - MedPage Today

Autoantibodies a Big Deal in Sjogren's - MedPage Today | AUTOIMMUNITY | Scoop.it
Autoantibodies a Big Deal in Sjogren's MedPage Today Over the past 20 years, Sjogren's syndrome has increasingly been recognized as an autoimmune disease, with the presence of autoantibodies and focal lymphocytic sialadenitis as evidence of an...
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Scooped by Gilbert C FAURE
November 3, 2013 1:57 PM
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Lack of adiponectin leads to increased lymphoc... [Eur J Immunol. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:
in EAE model of MS
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