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Scooped by
Gilbert C FAURE
July 4, 2014 2:57 PM
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RT @Immunology_News: Enhanced autoantibody production and Mott cell formation in Fc{mu}R-deficient autoimmune mice http://t.co/YlP9ijruhz
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Suggested by
Société Francaise d'Immunologie
July 4, 2014 2:55 PM
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Systemic lupus erythematosus (SLE) is a human chronic inflammatory disease generated and maintained throughout life by autoreactive T and B cells.
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Scooped by
Gilbert C FAURE
July 3, 2014 2:40 PM
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New B-Cell Drug Disappoints in Lupus
MedPage Today
One monoclonal antibody that targets B-lymphocyte stimulator (BLyS), belimumab (Benlysta) has been approved by the FDA based on the results of two phase III trials.
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Scooped by
Gilbert C FAURE
July 3, 2014 2:14 PM
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Scooped by
Gilbert C FAURE
July 3, 2014 2:08 PM
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Anti-basal ganglia antibodies in primary obsessive-compulsive disorder ...
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Scooped by
Gilbert C FAURE
July 3, 2014 5:58 AM
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The West Australian Diabetes trigger found by WA team The West Australian Part of a global consortium, scientists from the Harry Perkins Institute for Medical Research have identified an area of DNA linked to the autoimmune condition that affects...
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Scooped by
Gilbert C FAURE
July 2, 2014 2:34 PM
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A positive Anti-Neutrophil Cytoplasm Antibody (ANCA) test administered to patients with a high probability for vasculitis has high sensitivity and specificity...
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Scooped by
Gilbert C FAURE
July 1, 2014 11:37 AM
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The type I interferon system plays a critical role in host defense in health, and a growing body of literature suggests that type I interferon is a critical mediator of human autoimmune disease [1]...
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Scooped by
Gilbert C FAURE
June 30, 2014 2:53 PM
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Dogs with #Pemphigus foliaceus rarely have IgM, IgA, IgE autoantibodies, IgG autoantibody response predominant type http://t.co/btuWsSEQdP
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Scooped by
Gilbert C FAURE
June 30, 2014 2:45 PM
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Also, persons with type 1 diabetes are prone to other autoimmune disorders, such as autoimmune thyroid disease. In cases that are less than clear-cut, measuring autoantibodies can provide useful information.
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Scooped by
Gilbert C FAURE
June 27, 2014 3:53 PM
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Penn study reveals a common genetic link in fatal autoimmune skin disease
EurekAlert (press release)
PHILADELPHIA – Autoimmune disease occurs when the body's own natural defense system rebels against itself.
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Scooped by
Gilbert C FAURE
June 27, 2014 5:55 AM
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Autoimmune disease occurs when the body's own natural defense system rebels against itself. One example is pemphigus vulgaris (PV), a blistering skin disease in which autoantibodies attack desmoglein 3 (Dsg3), the protein that binds ...
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Scooped by
Gilbert C FAURE
June 25, 2014 3:35 PM
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Scooped by
Gilbert C FAURE
July 4, 2014 2:56 PM
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It is not known whether or not this risk is associated with angiotensin II receptor type 1 autoantibody (AT1-AA), an agonist acting via activation of AT1 receptor (AT1R), which is believed to be involved in the pathogenesis of ...
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Suggested by
Société Francaise d'Immunologie
July 4, 2014 2:54 PM
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Autoreactive T cells infiltrating the target organ can possess a broad TCR affinity range. However, the extent to which such biophysical parameters contribute to T cell pathogenic potential remains unclear.
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Scooped by
Gilbert C FAURE
July 3, 2014 2:16 PM
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Scooped by
Gilbert C FAURE
July 3, 2014 2:12 PM
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What a clinician needs to know about autoantibody assays: value added reporting of autoimmune serology - http://t.co/kELJH8ddUP
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Scooped by
Gilbert C FAURE
July 3, 2014 2:04 PM
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Science Codex Risk of Celiac, Autoimmunity High With DR3-DQ2 Haplotype Doctors Lounge There is a high risk for celiac disease autoimmunity and celiac disease early in childhood among those with HLA haplotype DR3-DQ2, according to a study published...
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Scooped by
Gilbert C FAURE
July 2, 2014 2:39 PM
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The JHU Gazette A conversation with pathologist Noel Rose, the father of autoimmunology The JHU Gazette One of the things that my father became very interested in was rheumatic fever, which we now know to be an autoimmune disease caused by a strep...
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Rescooped by
Gilbert C FAURE
from Rheumatology-Rhumatologie
July 2, 2014 8:55 AM
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Scooped by
Gilbert C FAURE
June 30, 2014 3:07 PM
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The term antinuclear antibody (ANA) describes a variety of autoantibodies that react with constituents of cell nuclei including DNA, proteins and ribonucleoproteins1,2. The HEp-2 cell, a native protein array with hundreds of ...
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Scooped by
Gilbert C FAURE
June 30, 2014 2:46 PM
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PLOS Genetics is an open-access (Our paper in @PLOSGenetics - relationship between resting/stim eQTLs in CD4+ T cells and autoimmunity.
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Scooped by
Gilbert C FAURE
June 28, 2014 3:49 PM
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IntroductionIgG4-related disease (IgG4-RD) is a multisystem-involved autoimmune disease. Abnormally activated and differentiated B cells may play important roles.
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Scooped by
Gilbert C FAURE
June 27, 2014 5:58 AM
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There are over 100 Autoimmune disorders and blogs that can help you to live with them. Check out the big list here.
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Scooped by
Gilbert C FAURE
June 26, 2014 6:17 AM
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RF detected by agglutination of tanned IgG-loaded erythrocytes is involved in negative idiotypic regulation of lymphocytes specific to autoimmunity-inducing antigens. PubMed, Int J Rheum Dis. 2014 Mar 26.
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Scoop.it!
IgM-Fc receptor (FcμR) is involved in IgM homeostasis as evidenced by increased pre-immune serum IgM and natural autoantibodies of both IgM and IgG isotypes in Fcmr-deficient C57BL/6 (B6) mice. To determine the impact of Fcmr ablation on autoimmunity, we introduced the Fcmr null mutation onto the Fas-deficient autoimmune-prone B6.MRL Faslpr/lpr mouse background (B6/lpr).