Goals: We reviewed our celiac disease (CeD) database to study if anti-tissue transglutaminase (tTG) antibody (ab) titers correlate with severity of villous abnormalities in Indian patients and to find out a cutoff value of anti-tTG ab fold-rise,...
Chronic inflammatory conditions, such as in autoimmune disease, can disturb immune cell homeostasis and induce the expansion of normally rare cell populations.
by Hao Chen, Donghang Zheng, Sriram Ambadapadi, Jennifer Davids, Sally Ryden, Hazem Samy, Mee Bartee, Eric Sobel, Erbin Dai, Liying Liu, Colin Macaulay, Anthony Yachnis, Cornelia Weyand, Robert Thoburn, Alexandra Lucas Giant cell arteritis (GCA)...
Cellular and Molecular Immunology aims to report the dynamic progress being made in China and abroad in immunological research, and welcomes high-quality Research Articles, Reviews and Brief Reports across a broad range of topics including, but not limited to, clinical immunology, comparative immunology, immunobiology, immunogenetics, immunological techniques, immunopathology, immunopharmacology, infection immunology, neuroimmunology, transplantation immunology, tumor immunology, and veterinary immunology.
Cytosolic DNA-sensing pathways that signal via Stimulator of interferon genes (STING) mediate immunity to pathogens and also promote autoimmune pathology in DNaseII- and DNaseIII-deficient mice. In contrast, we report here that STING potently suppresses inflammation in a model of systemic lupus erythematosus (SLE)
Despite the prevalence of Sjögren’s syndrome – an autoimmune disease most commonly known for causing dry eyes and mouth - a lack of knowledge about how the condition starts has stalled the development of new treatments.
Authors: Arnab Bhattacharjee, Stefanie Reuter, Eszter Trojnár, Robert Kolodziejczyk, Harald Seeberger, Satu Hyvärinen, Barbara Uzonyi, Ágnes Szilágyi, Zoltán Prohászka, Adrian Goldman, Mihály Józsi, T Sakari Jokiranta, Discipline: Medicine, Type: ...
It is unclear why selective deficiency in secreted (s)IgM causes Ab-mediated autoimmunity. We demonstrate that sIgM is required for normal B cell development and selection.
Approximately 60 percent of individuals infected with Ebola have died since the latest outbreak in West Africa, a sad statistic representing almost 9,000 deaths over the last 7 months. Survivors co...
by Cinzia Scambi, Sara Ugolini, T. Sakari Jokiranta, Lucia De Franceschi, Oscar Bortolami, Valentina La Verde, Patrizia Guarini, Paola Caramaschi, Viviana Ravagnani, Guido Martignoni, Chiara Colato, Serena Pedron, Fabio Benedetti, Marco Sorio,...
The next decade could see the development of a vaccine for type 1 diabetes, which could be given to infants or those with a susceptibility to the disease
BioMed Research International (formerly titled Journal of Biomedicine and Biotechnology) is a peer-reviewed, open access journal that publishes original research articles as well as review articles in several areas of life sciences.
Dr. Michael Portman and Dr. Sadeep Shrestha, along with Dr. Brian McCrindle and Dr. Anne Rowley, discuss the immunology, immunopathology, and immunogenetics ...
Authors: Susanna Hamari, Tiina Kirveskoski, Virpi Glumoff, Petri Kulmala, Olli Simell, Mikael Knip, Jorma Ilonen, Riitta Veijola, Discipline: Medicine, Type: Journal Article
Researchers have identified genetic variants that are associated with psoriatic arthritis (PsA) but not with psoriasis, in the largest study of PsA ever published.
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