Virology News
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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
Curated by Ed Rybicki
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March 5, 2012 7:00 AM
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Will Schmallenberg virus outbreak cause UK livestock export ban?

Will Schmallenberg virus outbreak cause UK livestock export ban? | Virology News | Scoop.it
Laura Sandys, a Conservative MP for Kent, has called for a ban on the export of UK livestock due to a recent outbreak of the Schmallenberg virus.

Sandys argues that quick action now could prevent the virus from spreading. The BBC quoted her as saying, "There is no treatment or preventative vaccine available, nor are we are clear on how the virus is being transmitted."
To date, 92 UK farms have reported cases of Schmallenberg. The virus is named after the area in Germany where early cases were first reported. Schmallenberg is thought to be spread by biting insects like ticks and mosquitoes, and experts believe the virus entered the UK via small insects that were blown with the winds across the Channel. The first cases were identified in the UK in January.

Read more: http://www.digitaljournal.com/article/320628#ixzz1oF81hPmi

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March 5, 2012 6:56 AM
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Sun-dried tomatoes hepatitis link

Sun-dried tomatoes hepatitis link | Virology News | Scoop.it

UK health experts believe sun-dried tomatoes could be the cause of a recent outbreak of hepatitis A.  Four of the patients in this latest outbreak in England said they had consumed sun-dried tomatoes.  Officials are on the alert for further cases. But they say they do not know which brands of sun-dried tomatoes might be involved. This is because there is no reliable test to find the virus in food.

 

Welcome to the developing world, folks...B-)

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March 4, 2012 2:37 PM
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The Subcellular World Revealed, 1945 | The Scientist

The Subcellular World Revealed, 1945 | The Scientist | Virology News | Scoop.it

Using a new culture technique developed by Claude’s Rockefeller colleague, Keith Porter, the team prepared chicken fibroblasts that were stretched thin enough to be penetrated by the microscope’s electron beam, but that were not distorted or greatly altered by the process. In 1945 the trio published a description of their technique along with the first electron micrograph of an intact cell in the Journal of Experimental Medicine

 

Great slideshow of early EM

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March 4, 2012 8:30 AM
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Rubella virus-like replicon particles: analysis of encapsidation determinants and non-structural roles of capsid protein in early post-entry replication

This study describes development and use of a trans-encapsidation system for the assembly of infectious RUBV-like replicon particles (VRPs) containing RUBV replicons (self replicating genomes with the SP-ORF replaced with a reporter gene). First, this system was used to map signals within the RUBV genome that mediate packaging of viral RNA. Mutations within a proposed packaging signal did not significantly affect relative packaging efficiency. The insertion of various fragments derived from the RUBV genome into Sindbis virus replicons revealed that there are several regions within the RUBV genome capable of enhancing encapsidation of heterologous replicon RNAs

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March 4, 2012 8:15 AM
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Haight-Ashbury Avian Swine Flu

Eclectic and nothing obviously to do with viruses at all.  Haight Ashbury: still far out, man....

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March 4, 2012 8:10 AM
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Lab-engineered bird flu virus may be less deadly than thought — or not

Lab-engineered bird flu virus may be less deadly than thought — or not | Virology News | Scoop.it
The engineered bird flu virus may not be as lethal as originally reported, a conference is told.

 

Ron A.M. Fouchier of Erasmus Medical Center in Rotterdam... said the team infected six ferrets with wild virus and six with engineered virus by spraying the bug directly down their throats into their windpipes. All of the animals in both groups died. The team then sprayed an unusually high dose of each virus into the nasal passages of ferrets. Two animals that got the wild virus by this route died, but the engineered virus was fatal to only one in eight animals. The team then put ferrets infected with the engineered virus next to caged, uninfected animals. Seven animals became infected, but none died....

 

And round and round we go, again.  I thank Russell Kightley Media for the image.

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March 4, 2012 7:43 AM
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Presentation of vaccine against Hepatitis in Biotechnology Havana 2012 | Cuba News Headlines. Cuban Daily News

Presentation of vaccine against Hepatitis in Biotechnology Havana 2012 | Cuba News Headlines. Cuban Daily News | Virology News | Scoop.it

Several developments in Congress will present Cuba Biotechnology Havana 2012, among them is the therapeutic vaccine against hepatitis B infection (Nasvac) that scored well in the last phase of clinical trials.
Read more: http://www.cubaheadlines.com/2012/03/04/34731/presentation_of_vaccine_against_hepatitis_in_biotechnology_havana_2012.html#ixzz1o9SEjWzz
Original article here!

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March 4, 2012 7:37 AM
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Rotavirus Vaccine Is Safe, Study Finds – General News | VozNews ...

A vaccine against rotavirus was in wide use until it was pulled from the market a few years ago because of safety concerns. A study in the Journal of the American Medical Association examines the safety and effectiveness of ...
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March 4, 2012 7:25 AM
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Delivering Silence | The Scientist

Delivering Silence | The Scientist | Virology News | Scoop.it
Since the discovery of RNA interference almost 15 years ago, researchers have tried to devise effective ways to get these short gene-silencing transcripts inside cells. But techniques for in vivo delivery have fallen short. For therapies that require long-term gene knockdown, DNA viruses that insert the microRNA (miRNA) genes into the target cell’s genome were the best bet. But that approach produced large numbers of miRNAs, which overloaded the miRNA-processing proteins in the nucleus and resulted in cellular toxicity. For short-term therapies, mature miRNAs encapsulated in liposomes or conjugated to cholesterol were used, but they have been difficult to target to a specific cell type.
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March 1, 2012 1:46 AM
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HIV-positive maid laced kid's porridge with menstrual blood

HIV-positive maid laced kid's porridge with menstrual blood | Virology News | Scoop.it
We never want to hear Goldilocks complain about the temperature of her breakfast again. An HIV-positive maid from Zimbabwe was arrested after lacing the porridge of her employer's 4-year-old child with menstrual blood.

Never, NEVER piss off the help....
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February 29, 2012 3:56 PM
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Trade Secrets: We Will Speak for You

Trade Secrets: We Will Speak for You | Virology News | Scoop.it
It will have been very hard to miss, in recent weeks, the worldwide furore that has erupted over the so-called “killer flu” that came out of laboratories in The Netherlands and in Wisconsin.  Essentially, for those living under a rock somewhere, both...

Ed gets annoyed.
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February 28, 2012 2:10 PM
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allAfrica.com: South Africa: New Reports Chart Progress - and Costs - in HIV Fight

allAfrica.com: South Africa: New Reports Chart Progress - and Costs - in HIV Fight | Virology News | Scoop.it
Although in its sixth year of publication, this year's barometer is the first to include data on early infant HIV testing for babies born to HIV-positive mothers and shows that about half of all babies born to HIV-positive mothers are now being tested for the virus at six weeks of age, an important step to ensuring they access the early HIV treatment recommended for all children younger than one under national guidelines. In 2009, only about a quarter of such babies were being tested using the sensitive polymerase chain reaction - tests that confirm whether HIV-exposed infants are HIV-positive.

The report also found that almost all pregnant women are now tested for HIV, which has helped lower mother-to-child HIV transmission to below 4 percent in the country.

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February 28, 2012 2:04 PM
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Flu Virus Discovered In Bats

Flu Virus Discovered In Bats | Virology News | Scoop.it
Scientists from the US Centers for Disease Control and Prevention (CDC) have discovered evidence of a new influenza type A virus in Guatemalan fruit bats.

 

"...for reassortment to occur, the bat flu virus would have to be capable of infecting a different animal, such as a pig, horse or dog, at the same time as a human flu virus.

So far, the bat flu virus has only been found in little yellow-shouldered bats. These fruit bats are not native to the US, but quite common in Central and South America. The bats don't bite people, but it is feasible they could shed the virus onto foods like fruit and vegetables that are then eaten by humans and other animals."

 

And if you watched "Contagion", you will remember the bulldozer knocking down the tree, which disturbed the bat, which roosted in a pigpen, where pigs ate the faeces, and - recombination occurred!

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March 5, 2012 6:58 AM
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HIV transmission to KZN children down - Pretoria News | IOL.co.za

HIV transmission to KZN children down - Pretoria News | IOL.co.za | Virology News | Scoop.it

The rate of HIV transmission from mother to child in KwaZulu-Natal has dropped from 22 percent to 2.8 percent in the past four years, Premier Zweli Mkhize said on Tuesday.

“While KwaZulu-Natal has been known as the epicentre of the HIV and Aids pandemic, there are signs that the battle is being won, albeit slowly,” he said in his state of the province address in Pietermaritzburg.

The province was slowly winning the battle against the pandemic because of the work of the provincial council on HIV/Aids, he said.

The council includes government at all levels, civil society, labour, churches, the media and traditional leaders.

Mkhize said more than 500 000 HIV patients were on antiretroviral treatment in the province.

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March 4, 2012 2:56 PM
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Skin-Deep Immunity | The Scientist

Skin-Deep Immunity | The Scientist | Virology News | Scoop.it
The smallpox vaccine was the first, and arguably most successful, vaccine ever put into practice, and it was scratched into the skin of individuals. With the invention of syringes and hypodermic needles, vaccination shifted toward administration directly into the muscle, under the assumption that it is better to get a vaccine straight into the body. But it turns out scientists may have had it right the first time.
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March 4, 2012 8:32 AM
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Reintroduction of H5N1 highly pathogenic avian influenza virus by migratory water birds, causing poultry outbreaks in the 2010–2011 winter season in Japan

H5N1 highly pathogenic avian influenza virus (HPAIV) was reintroduced and caused outbreaks in chickens in the 2010–2011 winter season in Japan, which had been free from highly pathogenic avian influenza (HPAI) since 2007 when HPAI outbreaks occurred and were controlled. On 14 October 2010 at Lake Ohnuma, Wakkanai, the northernmost part of Hokkaido, Japan, H5N1 HPAIVs were isolated from faecal samples of ducks flying from their nesting lakes in Siberia. Since then, in Japan, H5N1 HPAIVs have been isolated from 63 wild birds in 17 prefectures and caused HPAI outbreaks in 24 chicken farms in nine prefectures by the end of March in 2011. Each of these isolates was genetically closely related to the HPAIV isolates at Lake Ohnuma, and those in China, Mongolia, Russia and Korea, belonging to genetic clade 2.3.2.1.

 

Add something new to the list of vectors of viruses: ducks.  Much more impressive than a mosquito.

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March 4, 2012 8:18 AM
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First influenza vaccine protecting against 4 strains approved by FDA

First influenza vaccine protecting against 4 strains approved by FDA...two strains of influenza A and two strains of influenza B, and is approved for people ages 2 to 49. Similar to the previously approved FluMist, the new vaccine is a nasal spray that delivers weakened strains of the virus.
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March 4, 2012 8:11 AM
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Dion awaits word on respite's length - Las Vegas Review - Journal

Dion awaits word on respite's length - Las Vegas Review - Journal | Virology News | Scoop.it
CBC.caDion awaits word on respite's lengthLas Vegas Review - JournalCeline Dion will find out in 10 days how she's progressing in her battle with a virus that wiped out her entire February and March engagement at Caesars Palace.

 

Go virus...!

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March 4, 2012 7:46 AM
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Herbal Supplement for HIV/AIDS is Successful in Clinical Trial

Herbal Supplement for HIV/AIDS is Successful in Clinical Trial | Virology News | Scoop.it
A clinical trial using a herbal mix of oleander and suthrelandia frutescens is 100 percent successful in stabliizing and reversing HIV symptoms...

 

At first sight, just snake oil.  And yet...double-blinded placebo controlled trials are difficult to fake.

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March 4, 2012 7:41 AM
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Productive Replication of Ebola Virus Is Regulated by the c-Abl1 Tyrosine Kinase

Here, we report that productive replication of Ebola virus is modulated by the c-Abl1 tyrosine kinase. Release of Ebola virus–like particles (VLPs) in a cell culture cotransfection system was inhibited by c-Abl1–specific small interfering RNA (siRNA) or by Abl-specific kinase inhibitors and required tyrosine phosphorylation of the Ebola matrix protein VP40. Expression of c-Abl1 stimulated an increase in phosphorylation of tyrosine 13 (Y13) of VP40, and mutation of Y13 to alanine decreased the release of Ebola VLPs.

 

My favourite "scare the children" virus, becoming better understood

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March 4, 2012 7:36 AM
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The Specter of Denialism | The Scientist

The Specter of Denialism | The Scientist | Virology News | Scoop.it

There is a substantial body of evidence showing that HIV causes AIDS—and that antiretroviral treatment (ART) has turned the viral infection from a death sentence into a chronic disease.1 Yet a small group of AIDS denialists keeps alive the conspiratorial argument that ART is harmful and that HIV science has been corrupted by commercial interests.

 

Cape Town's own Nicoli Nattrass!

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March 1, 2012 1:52 AM
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Flu vaccine symposium in Johannesburg

I am presently sitting in the Poliomyelitis Research Foundation's conference centre in Sandringham, Johannesburg, attending the 8th Annual Influenza Symposium meeting - whose focus this year is Flu Vaccines. And we are told the flu B vaccine last yeard did not match the seasonal virus, so we had a two-hump incidence curve in South Africa, with an early H1N1 2009 peak, and a later B and H3N2 peak. And they didn't plan to change the vaccine for this year....
Fascinating stuff!

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March 1, 2012 1:44 AM
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Study finds HIV-specific CD4 cells that control viral levels

Study finds HIV-specific CD4 cells that control viral levels | Virology News | Scoop.it
A subpopulation of the immune cells targeted by HIV may play an important role in controlling viral loads after initial infection, potentially helping to determine how quickly infection will progress.

Interesting...so it's not just CD8 T cells that directly control HIV-infected cells.
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February 28, 2012 2:14 PM
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Antivirals for Treatment of Influenza: A Systematic Review and Meta-analysis of Observational Studies

Antivirals for Treatment of Influenza: A Systematic Review and Meta-analysis of Observational Studies | Virology News | Scoop.it

Meta-analyses of the few studies providing effects with adjustment for confounders suggest that in high-risk populations, oral oseltamivir may reduce mortality (odds ratio, 0.23 [95% CI, 0.13 to 0.43]; low-quality evidence), hospitalization (odds ratio, 0.75 [CI, 0.66 to 0.89]; low-quality evidence), and duration of symptoms (33 hours [CI, 21 to 45 hours]; very low–quality evidence) compared with no treatment. Earlier treatment with oseltamivir was generally associated with better outcomes. Inhaled zanamivir may lead to shorter symptom duration (23 hours [CI, 17 to 28 hours]; moderate-quality evidence) and fewer hospitalizations (odds ratio, 0.66 [CI, 0.37 to 1.18]) but more complications than no treatment. Direct comparison of oral oseltamivir and inhaled zanamivir suggests no important differences in key outcomes. Data from 1 study suggests that oral amantadine may reduce mortality and pneumonia associated with influenza A. No included study evaluated rimantadine.

 

Image courtesy of Russell Kightley Media

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February 28, 2012 2:08 PM
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Mmegi Online :: Facebook is the new front in HIV/AIDS war

FRANCISTOWN: Poor knowledge about HIV/Aids and other sexually transmitted diseases among young people has compelled a Gaborone-based youth to create a group on the popular social network, Facebook, to enlighten his peers about the scourge.

 

Ex Africa, semper aliquid novi.  Or a Facebook page, in this case.

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