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Scoop.it!
by Merry Youle
Imagine that: they'll be spraying live bacteria next...oh, wait! They do!! 
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Even if a 59% mortality rate for H5N1 is too high, the virus could still cause a flu pandemic more serious than that of 1918.
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"HIV-1 Gag virus like particles (VLPs) used as candidate vaccines are regarded as inert particles as they contain no replicative nucleic acid, although they do encapsidate cellular RNAs."
In light of HPV VLPs being flagged as containing HPV DNA, this is interesting as it gives an idea of how to get rid of the NA in the HIV Pr55Gag particles. Plus, my lab wrote it.
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Washington, Feb 13 (IANS) A protein knocks out the most virulent form of HIV by starving it of the raw materials it needs to reproduce, in order to protect our immune cells, a study reveals.
...and this may be relevant for other viruses, like herpesviruses...
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![70% of oral cancers now traced to HPV [virus] | Virology News | Scoop.it](https://img.scoop.it/DtzAY_YT4ZRATqf_bGESSTl72eJkfbmt4t8yenImKBVvK0kTmF0xjctABnaLJIm9)
An estimated 7% of American teens and adults carry the human papilloma virus in their mouths, an infection that puts them at heightened risk of developing cancer of the mouth and throat, researchers say.
Of course, a goodly number of NON-Americans do, too...B-)
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"The FDA has recently received inquiries regarding the presence of human papillomavirus (HPV) DNA fragments in Gardasil and is aware that information related to this issue is on the internet."
The thing they don't mention is that there is probably OTHER yeast-derived DNA present as well, seeing as the VLPs are made in yeast - and that the HPV DNA is probably present in very low amounts detectable only by PCR
Picture courtesy of Russell Kightley Media
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Bullshit alert: Dr. Hanan Polansky, from the Center for the Biology of Chronic Disease, uses his highly acclaimed discovery of Microcompetition to explain how these DNA fragments [HPV L1 gene fragments] can cause major diseases.
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Amazon.com: HIV in South Africa: Talking About the Big Thing eBook: Corinne Squire: Kindle Store (HIV in South Africa: Talking About the Big Thing: No description available http://t.co/xmwpFxCW...)...
And it has the VERY interesting option of renting the book - for about $10.
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Great site, with a LOT of info on the search for HIV vaccines.
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In 1910, egyptologists discovered smallpox scars on the face of the mummy of Ramses V - the earliest evidence of smallpox in human history. Andrew explains the origins of the disease, and traces its spread into the modern era.
EXCELLENT series of short films on smallpox through the ages, courtesy of the Wellcome Trust - and AJ Cann, who tweeted it.
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"Immunizing boys and girls before they become sexually active, experts say, is the most effective way to prevent the spread of the human papilloma virus, or HPV, associated with genital warts and cancer. U.S. government advisory committee this October recommended that males between the ages of 11 and 21 be vaccinated against the human papilloma virus, believed responsible for thousands of new cancer cases in men and women each year. The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices further explained that the vaccine series can begin as early as age 9."
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...Elsevier's Virology was calmly publishing another paper on a "mutant" H5N1....
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Stomach Flu Sickens St. Maarten Cruise PassengersLEX18 Lexington KY NewsMaria Henry of the Collective Preventive Services says the Celebrity Silhouette disclosed the cases of gastroenteritis or stomach flu in its mandatory health declaration prior...
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THE SWINE flu vaccine has topped the list of drugs responsible for the largest number of suspected adverse reactions, new figures show.
...followed by (in third place) the HPV vaccine, then other childhood vaccines. But "Most of these were relatively mild, such as localised swelling, gastrointestinal problems and flu-like symptoms."
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HIV-resistant sex workers in Africa have a weak inflammatory response in their vaginas – a surprise for researchers, who were expecting the contrary considering the women’s high exposure to the virus.
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"These results suggest that cholesterol in the plasma membrane, dynamin- and clathrin-dependent endocytosis, and macropinocytosis play crucial roles in the entry of viruses bearing baculovirus GP64 into mammalian cells."
And VLPs: see next one....
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THE deadly virus sweeping through Melbourne's pigeons has been confirmed for the first time in other species, renewing urgent calls for a vaccine.
"the paramyxovirus" - WHICH paramyxovirus??!! We should be told....
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Health authorities have admitted to overreacting to a health scare at Auckland Airport but say it's better to be safe than sorry.
It's going to happen more often, people...I remember flying around Canada during the SARS breakout, and cringing and trying not to breathe every time the guy behind me coughed.
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Truth Alert: The Gardasil human papillomavirus (HPV) vaccine does not trigger autoimmune conditions in young women such as lupus, rheumatoid arthritis, type 1 diabetes or multiple sclerosis, according to a new study.
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Of profound interest to geminivirologists (he says, modestly). And hopefully, also to readers of Molecular Plant Pathology. Like Gary Foster...B-) Picture courtesy of Ben Odhiambo, of fond memory
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...and an excellent "journal club" site to bookmark for regular discussion papers on HIV-related topics
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Observe an ongoing dialogue on HIV information, infectious diseases, all matters medical, and some not so medical.
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Biologists have found new evidence of why mice, people and other vertebrate animals carry thousands of varieties of genes to make immune-system proteins named MHCs--even though some of those genes make vertebrate animals susceptible to infections and to autoimmune diseases.
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A Bangladeshi public health doctor, Asm Amjad Hossain, is the first recipient of the annual Gates Vaccine Innovation Award, which recognizes individuals who make significant contributions to advancing work in vaccine-preventable diseases.
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"...these results indicate that although host genetic diversity and viral entry may play some role in between-fish viral load variation, they are not major factors. Other biological and non-biological parameters that may influence viral load variation are discussed."
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