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Scooped by
Ed Rybicki
February 28, 2012 2:03 PM
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Tinderbox: How the West Sparked the AIDS Epidemic and How the World Can Finally Overcome It, attempts to pinpoint the birth and early life of HIV and AIDS. Considering a wealth of evidence, the authors suggest that the European Scramble for Africa during the late 19th and early 20th century helped turn localised outbreaks of the infection into a global epidemic.
Read more: http://www.dailymail.co.uk/health/article-2107605/HIV-epidemic-driven-colonialism-Africa-century-ago.html#ixzz1nhlAqwEM I suppose if you build roads and cities, people will use the roads to get to the cities - and bring whatever they have with them. Including viruses.
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Scooped by
Ed Rybicki
February 26, 2012 11:59 AM
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. Google Flu Trends has become a public health tool. Four years ago, Google launched Google Flu Trends, which estimates the prevalence of flu outbreaks based on how many people are searching for things like “fever” or “flu medication.” The search metrics have tracked incredibly closely with Center for Disease Control data.... Google: slowly assimilating everything you do.
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Scooped by
Ed Rybicki
February 26, 2012 11:56 AM
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Has vaccine reaction made cat lethargic?STLtoday.comI took her to the vet, had her checked out, vaccinated, etc. At the time, the vet estimated that she was about 2. The other day, I took her in for her yearly rabies shot. Do some people really have nothing better to worry about? How about: yes, there may be some reaction to the vaccine - BUT YOUR FRIKKIN' CAT WON'T GET RABIES!!!
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Scooped by
Ed Rybicki
February 26, 2012 11:52 AM
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While Virginia is moving to repeal the requirement that girls get vaccinated against the human papillomavirus, the federal government and a major medical association are urging just the opposite: that boys as well as girls receive the vaccine... There ought to be an IQ test to participate in civil society...
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Scooped by
Ed Rybicki
February 25, 2012 10:08 AM
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Lassa fever is a neglected tropical disease with significant impact on the health care system, society, and economy of Western and Central African nations where it is endemic. An older article, but... "LASV VLP can be generated displaying high levels of immunogenic viral proteins, and that small laboratory scale mammalian expression systems are capable of producing multi-milligram quantities of pseudoparticles. These VLP are structurally and morphologically similar to native LASV virions, but lack replicative functions, and thus can be safely generated in low biosafety level settings. LASV VLP were immunogenic in mice in the absence of adjuvants, with mature IgG responses developing within a few weeks after the first immunization. These studies highlight the relevance of a VLP platform for designing an optimal vaccine candidate against Lassa hemorrhagic fever, and warrant further investigation in lethal challenge animal models to establish their protective potential. People need to start paying attention to this virus...and another candidate for Green Technology.
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Scooped by
Ed Rybicki
February 25, 2012 9:57 AM
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Efforts have been made to eliminate wild poliovirus transmission since 1988 when the World Health Organization began its global eradication campaign. Since then, the incidence of polio has decreased significantly. However, serotype 1 and serotype 3 still circulate endemically in Pakistan and Afghanistan. Both countries constitute a single epidemiologic block representing one of the three remaining major global reservoirs of poliovirus transmission. In this study we used genetic sequence data to investigate transmission links among viruses from diverse locations during 2005-2007. The last places on the planet where wild-type polio is circulating: the focus will definitely become more obsessive
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Scooped by
Ed Rybicki
February 25, 2012 9:52 AM
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The Malian HIV Warrior Presidents Can't Say No ToAllAfrica.com He pressed China to admit that HIV was spreading rapidly among gay men and drug users and that the 500000 Chinese working in Africa and 40 million migrant labourers, many of whom visit...
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Scooped by
Ed Rybicki
February 24, 2012 8:20 AM
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Amazon.com: Phage Display In Biotechnology and Drug Discovery eBook: Sachdev S. "The first and only guide to showcase the impact of phage display technology on drug discovery, this reference details the theories, principles, and methods impacting the field and demonstrates applications for peptide phage display, protein phage display, and the development of novel antibodies. Highlighting the current and future role of phage display in the development of protein therapeutics, this book provides a comprehensive overview that will prove invaluable to anyone researching recombinant antibodies." Phages and biotechnology: what's not to like? The price, possibly??
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Scooped by
Ed Rybicki
February 24, 2012 7:01 AM
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There are four sexually transmitted diseases (STDs) that are caused by viruses. They are Human Immunodeficiency Virus (HIV), Human Papillomavirus (HPV), Herpes Simplex Virus (HSV), and Hepatitis C. Useful refresher, in case you thought it was time to get back on the circuit.
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Scooped by
Ed Rybicki
February 24, 2012 6:57 AM
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The editor of a leading scientific journal says he will publish full details of controversial research into the bird flu virus, unless the World Health Organization gives scientists crucial information. Go Bruce...!!
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Scooped by
Ed Rybicki
February 24, 2012 3:06 AM
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HIV has eluded vaccine-makers for thirty years, in part due to the virus' extreme ability to mutate. With a mathematical tool called random matrix theory, the team searched for high-order evolutionary constraints in the so-called Gag region of HIV. The researchers were looking for collectively co-evolving groups of amino acids with a high number of negative correlations (meaning multiple mutations would destroy the virus) and a low number of positive correlations (meaning the virus could survive multiple mutations). They found this combination in a region, which they call Gag sector 3, that is involved in stabilizing the protein shell of the virus: too many mutations here, and the virus' structure would collapse.
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Scooped by
Ed Rybicki
February 24, 2012 3:05 AM
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Vaccinating pregnant women against the flu protects their babies from being born too small, new research suggests. And, in the case of H1N1(2009) flu, may stop the mothers dying. Yet more reasons to vaccinate everyone!
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Scooped by
Ed Rybicki
February 22, 2012 3:54 AM
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Rabies is an avertable viral disease caused by the rabid animal to the warm blooded animals (zoonotic) especially human. Rabies occurs in more than 150 countries and territories. A very useful review on something that is an underestimated problem in developing countries. Image courtesy of Russell Kightley Media (http://www.rkm.com.au)
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Scooped by
Ed Rybicki
February 28, 2012 1:48 PM
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Weaponising bird flu? We don't need to weaponise no bird flu....
My family and I just watched "Contagion" on pay TV - and were most impressed. Reasonably true to life, all sorts of realistic scenarios, Ian Lipkin appearing as an extra - and one wonderful quote: "Someone doesn't have to weaponise the bird flu. The birds are doing that". Contagion is only a movie - but that's so true. Oh, and an uncredited appearance by Darren Martin's wonderful recombination analysis package, RDP 3.0 - at 1hr 15 min from the end.
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Scooped by
Ed Rybicki
February 26, 2012 11:57 AM
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Celine Dion cancels several Las Vegas shows due to virus that affects vocal cordsWashington PostLAS VEGAS — Singer Celine Dion has canceled several upcoming concerts in Las Vegas because of a virus. One could speculate as to what it is -like respiratory syncytial virus - or simply say "thank you, virus!"
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Scooped by
Ed Rybicki
February 26, 2012 11:54 AM
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Amazon.com: The Virus and the Vaccine: The True Story of a Cancer-Causing Monkey Virus, Contaminated Polio Vaccine, and the Millions of Americans Exposed (9780312278724): Debbie Bookchin, Jim Schumacher: Books (The Virus and the Vaccine: The True ... Sad thing is, it really is true - I've used it as a cautionary tale to my students for nigh on 30 years
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Scooped by
Ed Rybicki
February 26, 2012 7:00 AM
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Thousands of lambs have been killed by a new virus that is threatening the
survival of many British farms. Schmallenberg bites deep. Be interesting to see where it came from originally!
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Scooped by
Ed Rybicki
February 25, 2012 10:02 AM
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VLPs were subjected to post-purification disassembly and reassembly (D/R) treatment during bioprocessing to improve VLP immunoreactivity and stability. The post-D/R HPV16 VLPs and their complex with H16.V5 neutralizing antibody Fab fragments were visualized by cryo electron microscopy, showing VLPs densely decorated with antibody. Along with structural improvements, post-D/R VLPs showed markedly higher antigenicity to conformational and neutralizing monoclonal antibodies (mAbs) H16.V5, H16.E70 and H263.A2, whereas binding to mAbs recognizing linear epitopes (H16.J4, H16.O7, and H16.H5) was greatly reduced. Strikingly, post-D/R VLPs showed no detectable binding to H16.H5, indicating that the H16.H5 epitope is not accessible in fully assembled VLPs. An atomic homology model of the entire HPV16 VLP was generated based on previously determined high-resolution structures of bovine papillomavirus and HPV16 L1 pentameric capsomeres. Image courtesy of Russell Kightley Media
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Scooped by
Ed Rybicki
February 25, 2012 9:55 AM
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Bacteriophage T4 and Its Relatives.A Series of Critical Reviews: Amazon.co.uk: Jim D Karam, Eric S Miller: Books... Gotta love T4: it's EVERYWHERE...and the coolest piece of nanotechnology on the planet
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Scooped by
Ed Rybicki
February 25, 2012 9:49 AM
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Via VietNam News: Human trials for birdflu vaccine successful. Viet Nam has successfully produced experimental version of bird flu vaccine to combat the virus which has killed 62 people in 9 years, researchers at Vaccine and Biological Production Company No.1, said.
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Scooped by
Ed Rybicki
February 24, 2012 7:59 AM
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There were a number of changes to the 2012 clinical guidelines that doctors follow for adult immunizations, released by a federal panel. Yet another recommendation that young men get HPV vaccinations: time to start listening, boys!
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Scooped by
Ed Rybicki
February 24, 2012 6:59 AM
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"...these results suggest that inactivated SIV vaccines may potentiate clinical signs, inflammation and pneumonia following challenge with divergent homosubtypic viruses that do not share cross-reacting HI or SN antibodies." Or: getting vaccinated with the wrong strain may hurt you during an epi/pandemic.
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Scooped by
Ed Rybicki
February 24, 2012 3:06 AM
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The World Health Organization says the H5N1 bird flu kills nearly 60% of people who become infected, but a study released Thursday suggests the true fatality rate may actually be much lower. ...meaning a lot more people have been infected. Possibly meaning the next pandemic is closer than we thought.
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Scooped by
Ed Rybicki
February 24, 2012 3:06 AM
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The CDC says the strain has infected at least 18 Americans since 2010. SO while you were all fussing about H5N1....
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Scooped by
Ed Rybicki
February 24, 2012 2:52 AM
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A pharmaceutical giant is picking up the federal government's slack in funding a program aimed at curbing flu infections. ...and will inevitably own it....
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