NeuroImmunology
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Scooped by Gilbert C FAURE
March 18, 2014 7:17 AM
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Novel Approaches and Mechanisms of Immunotherapy for ...

Novel Approaches and Mechanisms of Immunotherapy for ... | NeuroImmunology | Scoop.it
Glioblastoma (GBM) is the most aggressive primary brain tumor. Combination therapy with surgery, radiation, and chemotherapy is not curative at present and carries a significant risk of toxicity. Advancements in the ...
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Scooped by Gilbert C FAURE
March 17, 2014 9:39 AM
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Efficacy and safety of nataliz... [J Neurol Neurosurg Psychiatry. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
March 13, 2014 11:42 PM
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Multiple sclerosis annual conference presents the latest on diagnosis, patient ... - Phys.Org

Multiple sclerosis annual conference presents the latest on diagnosis, patient ... - Phys.Org | NeuroImmunology | Scoop.it
Multiple sclerosis annual conference presents the latest on diagnosis, patient ...
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Scooped by Gilbert C FAURE
March 12, 2014 3:16 AM
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Higher Levels of Cerebrospinal Fluid α-Synuclein Predict Faster Cognitive Loss ... - 3BL Media (press release)

Higher Levels of Cerebrospinal Fluid α-Synuclein Predict Faster Cognitive Loss ... - 3BL Media (press release) | NeuroImmunology | Scoop.it
Higher Levels of Cerebrospinal Fluid α-Synuclein Predict Faster Cognitive Loss ...
Gilbert C FAURE's insight:

in parkinson

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Scooped by Gilbert C FAURE
March 11, 2014 12:29 AM
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Neural Representations of the Self and the Mother for Chinese Individuals

Neural Representations of the Self and the Mother for Chinese Individuals | NeuroImmunology | Scoop.it
by Gaowa Wuyun, Min Shu, Zhijun Cao, Wei Huang, Xin Zou, Sheng Li, Xin Zhang, Huan Luo, Yanhong Wu
An important question in social neuroscience is the similarities and differences in the neural representations between the self and close others.
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Scooped by Gilbert C FAURE
March 9, 2014 9:17 PM
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Blood test predicts Alzheimer's disease - CNN

Blood test predicts Alzheimer's disease - CNN | NeuroImmunology | Scoop.it
NPR (blog)
Blood test predicts Alzheimer's disease
CNN
(CNN) -- In a first-of-its-kind study, researchers have developed a blood test for Alzheimer's disease that predicts with astonishing accuracy whether a healthy person will develop the disease.
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Scooped by Gilbert C FAURE
March 9, 2014 12:36 AM
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Comprehensive Immunophenotyping of Cerebrospinal Fluid Cells in Patients with Neuroimmunological Diseases [AUTOIMMUNITY]

Comprehensive Immunophenotyping of Cerebrospinal Fluid Cells in Patients with Neuroimmunological Diseases [AUTOIMMUNITY] | NeuroImmunology | Scoop.it
We performed unbiased, comprehensive immunophenotyping of cerebrospinal fluid (CSF) and blood leukocytes in 221 subjects referred for the diagnostic work-up of neuroimmunological disorders to obtain insight about disease-specific phenotypes of...
Gilbert C FAURE's insight:

The study adds to the increasing number of publications that demonstrate poor correlation between systemic and intrathecal inflammatory biomarkers in patients with neuroimmunological diseases and stresses the importance of studying immune responses directly in the intrathecal compartment.

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Scooped by Gilbert C FAURE
March 6, 2014 5:39 AM
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PolygenicBlog: Autoantibody biomarkers in childhood-acquired demyelinating syndromes: results from a national surveillance cohort Journal of Neurology, Neurosurgery & Psychiatry

#Autoantibody biomarkers in childhood-acquired demyelinating syndromes: results from a… http://t.co/bJUkAjbUrX
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March 5, 2014 7:36 AM
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Randomized Phase II Multicentre Study to Investigate Efficacy of Autologous Lymphoid Effector Cells Specific Against Tumour-Cells (ALECSAT) in Patients With Glioblastoma Multiforme Measured Compare...

Allo- lymphoid effectors cells in glioblastoma (Denmark) Ph2 - recruiting! http://t.co/BcBndBeTRv (Sonsor: CytoVac)
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Scooped by Gilbert C FAURE
March 4, 2014 9:56 AM
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Body Fluid Cytokine Levels in Mild Cognitive I... [Mol Neurobiol. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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March 4, 2014 4:36 AM
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CNS inflammation other than multiple sclerosis: How likely is diagnosis?

CNS inflammatory disorders other than #MS are not uncommon in #neuroimmunology practice but often remain undiagnosed http://t.co/YVmk8LdyDE
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February 28, 2014 2:09 PM
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Overexpression of Suppressors of Cytoki... [Cell Physiol Biochem. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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February 27, 2014 3:45 PM
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JAMA Network | JAMA Neurology | Diagnostic Performance of Cerebrospinal Fluid Total Tau and Phosphorylated Tau in Creutzfeldt-Jakob Disease:  Results From the Swedish Mortality Registry

JAMA Network | JAMA Neurology | Diagnostic Performance of Cerebrospinal Fluid Total Tau and Phosphorylated Tau in Creutzfeldt-Jakob Disease:  Results From the Swedish Mortality Registry | NeuroImmunology | Scoop.it
Diagnostic Performance of Cerebrospinal Fluid Total Tau and Phosphorylated Tau in Creutzfeldt-Jakob Disease... http://t.co/Zg7xbqn0wk
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Scooped by Gilbert C FAURE
March 17, 2014 2:08 PM
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Call for papers

Neurology: Neuroimmunology & Neuroinflammation, the new online-only, open-access journal, is now calling for papers http://t.co/aij3d5qgZ1
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Scooped by Gilbert C FAURE
March 15, 2014 4:01 PM
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COX-2 drives metastatic breast cells from brain lesions into the cerebrospinal fluid and systemic circulation - yourcancer.info

Joshua E. Allen1, Akshal Patel2, Varun V Prabhu1, David T Dicker3, Jonas M. Sheehan2, Michael Glantz2, and Wafik S.
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March 13, 2014 10:01 AM
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Japanese encephalitis - World Health Organization (press release)

Japanese encephalitis
World Health Organization (press release)
To confirm JE infection and to rule out other causes of encephalitis requires a laboratory testing of serum or, preferentially, cerebrospinal fluid.
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March 11, 2014 9:37 PM
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Neuroimmunology: On the Frontier of Chronic Pain Research | Rheumatology Network

Neuroimmunology: On the Frontier of Chronic Pain Research | Rheumatology Network | NeuroImmunology | Scoop.it
Immune cells, the CNS, & frontiers of chronic #pain research. Podcast on RheumaNet #fibromyalgia#rheumedu #rheum http://t.co/5vxm3GPThf
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March 10, 2014 7:00 AM
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Gene Therapy Delivery of Myelin Oligodendrocyte Glycoprotein (MOG) via Hematopoietic Stem Cell Transfer Induces MOG-Specific B Cell Deletion [AUTOIMMUNITY]

Gene Therapy Delivery of Myelin Oligodendrocyte Glycoprotein (MOG) via Hematopoietic Stem Cell Transfer Induces MOG-Specific B Cell Deletion [AUTOIMMUNITY] | NeuroImmunology | Scoop.it
The various mechanisms that have been described for immune tolerance govern our ability to control self-reactivity and minimize autoimmunity.
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Scooped by Gilbert C FAURE
March 9, 2014 9:16 PM
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Cystatin C in Cerebrospinal Fluid is Upregulated in Elderly... : The ...

Cystatin C in Cerebrospinal Fluid is Upregulated in Elderly... : The ... | NeuroImmunology | Scoop.it
Objectives:Although high abundant cystatin c (CysC) in cerebrospinal fluid (CSF) is well known, its.
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Scooped by Gilbert C FAURE
March 6, 2014 9:22 AM
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New Published Paper Shows Efficacy of Lpath's Anti-LPA Antibody, Lpathomab ... - MarketWatch

New Published Paper Shows Efficacy of Lpath's Anti-LPA Antibody, Lpathomab ... - MarketWatch | NeuroImmunology | Scoop.it
New Published Paper Shows Efficacy of Lpath's Anti-LPA Antibody, Lpathomab ...
Gilbert C FAURE's insight:

As published by the Journal of Neuroinflammation (vol. 11, article 37), Lpathomabcan be used to reduce the size of a TBI and to improve functional behavioral outcomes in experimental animal models. The antibody works as a molecular sponge by soaking up lysophosphatidic acid (LPA), a molecule that can damage neurons and promote dangerous inflammatory responses in the central nervous system.

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March 6, 2014 4:29 AM
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Neuroimmunology: Obesity inflames memory circuits

Neuroimmunology: Obesity inflames memory circuits | NeuroImmunology | Scoop.it
From BioPortfolio: Adipose-derived interleukin-1Î⊃2; may mediate memory deficits in a mouse model of obesity. (Neuroimmunology Obesity inflames memory circuits - Adiposederived interleukin1 may mediate memory deficits in a mo...
Gilbert C FAURE's insight:

of mice

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March 4, 2014 2:54 PM
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Elevated glial fibrillary acidic protein levels in... [Sleep Med. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
March 4, 2014 4:37 AM
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Multiple Sclerosis Research: Fingolimod blocks pathway from the ...

Multiple Sclerosis Research: Fingolimod blocks pathway from the ... | NeuroImmunology | Scoop.it
Pharmacologic interruption of immune cell traffic with the mononuclear cell-sequestering drug fingolimod influenced anti-CNS T cell responses in the CxLNs and modulated experimental autoimmune encephalomyelitis (EAE) severity in a mouse model of...
Gilbert C FAURE's insight:

already posted but more figures available

Krishan Maggon 's curator insight, March 4, 2014 7:40 AM

Thanks to Prof Faure and MS Research 

 

J Clin Invest. 2014 Feb 24. pii: 71544. doi: 10.1172/JCI71544. [Epub ahead of print]Immune cell trafficking from the brain maintains CNS immune tolerance.Mohammad MG, Tsai VW, Ruitenberg MJ, Hassanpour M, Li H, Hart PH, Breit SN, Sawchenko PE, Brown DA.
Scooped by Gilbert C FAURE
March 3, 2014 8:12 AM
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Innate and adaptive immune responses in neurodegeneration and repair - Amor - 2014 - Immunology - Wiley Online Library

Innate and adaptive immune responses in neurodegeneration and repair - Amor - 2014 - Immunology - Wiley Online Library | NeuroImmunology | Scoop.it
Journal #Immunology (Current): "Innate & Adaptive #Immune Response in Neurodegeneration and Repair" http://t.co/z0PFIrdve5 … #neurology #CNS
Gilbert C FAURE's insight:

The articles highlight the role of the traditional resident immune cell of the CNS - the microglia - as well as the role of other glia astrocytes and oligodendrocytes in immune responses and their interplay with other immune cells including, mast cells, T cells and B cells.

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Scooped by Gilbert C FAURE
February 28, 2014 8:31 AM
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Diagnostic Performance of Cerebrospinal Fluid To... [JAMA Neurol. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:

In this routine clinical setting, the combination of increased T-tau levels and increased T-tau to P-tau ratios in CJD patients has a very high specificity against important differential diagnoses to CJD and may serve as a clinically useful diagnostic test.

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