NeuroImmunology
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Scooped by Gilbert C FAURE
January 30, 2015 1:50 PM
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The Ottawa Hospital leads first Canadian clinical trial of mesenchymal stem cell therapy for multiple sclerosis - OHRI

The Ottawa Hospital leads first Canadian clinical trial of mesenchymal stem cell therapy for multiple sclerosis - OHRI | NeuroImmunology | Scoop.it
Ottawa Hospital Research Institute
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January 29, 2015 3:09 PM
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Humoral Response against Small Heat Shock Proteins in Parkinson’s Disease

Humoral Response against Small Heat Shock Proteins in Parkinson’s Disease | NeuroImmunology | Scoop.it
by Ewa Papuć, Ewa Kurys-Denis, Witold Krupski, Konrad Rejdak Introduction In the light of evidence for the increased heat shock proteins (HSP) expression in neurodegenerative disorders, the presence of the adaptive humoral response of the immune...
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January 28, 2015 1:22 PM
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Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Li... - PubMed - NCBI

Neuron. 2015 Jan 21. pii: S0896-6273(14)01201-X. doi: 10.1016/j.neuron.2014.12.068. [Epub ahead of print]
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January 26, 2015 10:12 AM
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UAB working on rapid meningitis test - WAAY

UAB working on rapid meningitis test - WAAY | NeuroImmunology | Scoop.it
The University of Alabama at Birmingham (UAB) Institute for Innovation and Entrepreneurship is teaming up with a medical device startup to create a faster way to diagnose bacterial meningitis, a deadly bacterial infection. ...
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January 24, 2015 2:53 AM
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Blood vessels in older brains break down, possibly leading to Alzheimer's - Medical Xpress

Blood vessels in older brains break down, possibly leading to Alzheimer's - Medical Xpress | NeuroImmunology | Scoop.it
University of Southern California (USC) neuroscientists may have unlocked another puzzle to preventing risks that can lead to Alzheimer's disease.
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January 24, 2015 2:52 AM
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Bevacizumab is Safe, Effective for Recurrent Glioblastoma - Neurology Advisor

Bevacizumab is Safe, Effective for Recurrent Glioblastoma - Neurology Advisor | NeuroImmunology | Scoop.it
70.8% of patients saw improved performance status while on single-agent bevacizumab.
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January 22, 2015 3:34 AM
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Hematopoietic Stem Cell Transplantation for MS: Extraordinary Evidence Still ... - JAMA: The Journal of the American Medical Association

Hematopoietic Stem Cell Transplantation for MS: Extraordinary Evidence Still ... - JAMA:  The Journal of the American Medical Association | NeuroImmunology | Scoop.it
Multiple sclerosis (MS) is a central nervous system disorder characterized by inflammation, loss of the insulating tissue (myelin) surrounding and protecting nerve axons, and multifocal scarring.1 Multiple sclerosis is a prototypic autoimmune...
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January 21, 2015 1:40 PM
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Higher incidence of Epstein-Barr virus-induced lymphocyte transform... - PubMed - NCBI

Acta Neurol Scand. 2014 Aug;130(2):90-6. doi: 10.1111/ane.12249. Epub 2014 Mar 31. Research Support, Non-U.S. Gov't
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January 20, 2015 2:17 PM
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Helicobacter pylori infection as a protective factor against multiple sclerosis risk in females -- Fabis Pedrini et al. -- Journal of Neurology, Neurosurgery & Psychiatry

RT @NatRevNeurol: Helicobacter pylori infection as a protective factor against multiple sclerosis risk in females http://t.co/gfwTpPMbyE
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January 20, 2015 2:12 PM
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Staying dirty can help prevent multiple sclerosis

Staying dirty can help prevent multiple sclerosis | NeuroImmunology | Scoop.it
The presence of antibodies to the bacterium Helicobacter pylori are correlated with a lower incidence of multiple sclerosis in women.
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January 20, 2015 2:10 PM
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A clinical and laboratory study evaluating the profile of cytokine ... - PubMed - NCBI

J Neuroimmunol. 2015 Jan 15;278C:53-59. doi: 10.1016/j.jneuroim.2014.12.005. Epub 2014 Dec 5.
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January 19, 2015 1:42 PM
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A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes -- Magdalinou et al. -- Journal of Neurology, Neurosurgery & Psychiatry

A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes http://t.co/a98s1Ibb26
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January 19, 2015 1:34 PM
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Affinity Proteomic Profiling of Plasma, Cerebrospinal Fluid, and Brain Tissue within Multiple Sclerosis - Journal of Proteome Research (ACS Publications)

Affinity Proteomic Profiling of Plasma, Cerebrospinal Fluid, and Brain Tissue within Multiple Sclerosis - Journal of Proteome Research (ACS Publications) | NeuroImmunology | Scoop.it
Affinity Proteomic Profiling of Plasma, Cerebrospinal Fluid, and Brain Tissue within Multiple Sclerosis: http://t.co/R3FVI00j8H
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January 30, 2015 8:36 AM
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Alectinib active against leptomeningeal metastases in ALK-positive NSCLC - News-Medical.net

Alectinib active against leptomeningeal metastases in ALK-positive NSCLC - News-Medical.net | NeuroImmunology | Scoop.it
Patients with anaplastic lymphoma kinase-rearranged non-small-cell lung cancer who have leptomeningeal metastases may benefit from treatment with the second-generation ALK inhibitor alectinib, a case series suggests.
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Scooped by Gilbert C FAURE from Multiple sclerosis New Drugs Review
January 28, 2015 2:11 PM
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Acta Neuropathologica Communications | Full text | Categorization of multiple sclerosis relapse subtypes by B cell profiling in the blood

B cells are attracting increasing attention in the pathogenesis of multiple sclerosis (MS). B cell-targeted therapies with monoclonal antibodies or plasmapheresis have been shown to be successful in a subset of patients.

Via Krishan Maggon
Krishan Maggon 's curator insight, January 28, 2015 10:45 AM

Acta Neuropathol Commun. 2014 Sep 16;2:138. doi: 10.1186/s40478-014-0138-2.Categorization of multiple sclerosis relapse subtypes by B cell profiling in the blood.Hohmann C, Milles B, Schinke M, Schroeter M, Ulzheimer J, Kraft P, Kleinschnitz C, Lehmann PV, Kuerten S. 

Acta Neuropathologica Communications 2014, 2:138  doi:10.1186/s40478-014-0138-2

The electronic version of this article is the complete one and can be found online at:http://www.actaneurocomms.org/content/2/1/138


Received:17 July 2014Accepted:5 September 2014Published:16 September 2014

© 2014 Hohmann et al.; licensee BioMed Central Ltd. 

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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January 26, 2015 1:49 PM
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New Roles of Glycosaminoglycans in α-Synuclein Aggregation in a Cellular Model of Parkinson Disease

New Roles of Glycosaminoglycans in α-Synuclein Aggregation in a Cellular Model of Parkinson Disease | NeuroImmunology | Scoop.it
by Sonia Lehri-Boufala, Mohand-Ouidir Ouidja, Véronique Barbier-Chassefière, Emilie Hénault, Rita Raisman-Vozari, Laure Garrigue-Antar, Dulce Papy-Garcia, Christophe Morin The causes of Parkinson disease (PD) remain mysterious, although some...
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January 24, 2015 10:06 AM
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Killer-cell immunoglobulin-like receptor expression on lymphocyte s... - PubMed - NCBI

CNS Drugs. 2014 Jun;28(6):559-70. doi: 10.1007/s40263-014-0153-7. Clinical Trial; Research Support, Non-U.S. Gov't
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January 24, 2015 2:53 AM
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Natural Killer Cell Subsets in Cerebrospinal Fluid of Patients with Multiple Sclerosis - Rodríguez-Martín - Clinical & Experimental Immunology - Wiley Online Library

Natural Killer Cell Subsets in Cerebrospinal Fluid of Patients with Multiple Sclerosis - Rodríguez-Martín - Clinical & Experimental Immunology - Wiley Online Library | NeuroImmunology | Scoop.it
Natural Killer Cell Subsets in Cerebrospinal Fluid of Patients with Multiple Sclerosis - Rodríguez-Martín -http://t.co/A3NOj3QRTX
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Scooped by Gilbert C FAURE
January 23, 2015 1:48 PM
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Isolation of Brain and Spinal Cord Mononuclear Cells Using Percoll Gradients

To watch this video on jove.com, click here: http://www.jove.com/video/2348?utm_source=youtube&utm_medium=youtube_video&utm_campaign=youtube The current article describes a rapid protocol.
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January 21, 2015 2:10 PM
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Role of High Mobility Group Box 1 (HMGB1) in SCA17 Pathogenesis

Role of High Mobility Group Box 1 (HMGB1) in SCA17 Pathogenesis | NeuroImmunology | Scoop.it
by Li-Ching Lee, Chiung-Mei Chen, Pin-Rong Wang, Ming-Tsan Su, Guey-Jen Lee-Chen, Chun-Yen Chang Spinocerebellar ataxia type 17 (SCA17) involves the expression of a polyglutamine (polyQ) expanded TATA-binding protein (TBP), a general transcription...
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Scooped by Gilbert C FAURE from Top Selling Monoclonal Antibodies
January 21, 2015 4:14 AM
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biOasis Technologies Inc. Blood Brain Barrier Platform Attracts Majors - Midas Letter

biOasis Technologies Inc. Blood Brain Barrier Platform Attracts Majors - Midas Letter | NeuroImmunology | Scoop.it
biOasis Technologies Inc. (TSX.V:BTI) (OTCMKTS:BIOAF) use of peptides to transport therapeutic drugs across the blood brain barrier is attracting the attention of major biotech partners.

Via Krishan Maggon
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January 20, 2015 2:15 PM
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Tiny lumps of calcium phosphate may trigger age-related macular degeneration

Tiny lumps of calcium phosphate may trigger age-related macular degeneration | NeuroImmunology | Scoop.it
New research from scientists at the University of Maryland School of Medicine has found that tiny lumps of calcium phosphate may be an important triggering factor for age-related macular degeneration (AMD), a degenerative eye disease that can cause...
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apatite deposition disease!

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January 20, 2015 2:10 PM
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Chemokine-mediated inflammation in the degenerating retina is coord... - PubMed - NCBI

J Neuroinflammation. 2015 Jan 17;12(1):8. [Epub ahead of print]
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January 19, 2015 1:43 PM
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BMC Neuroscience | Full text | Regulation of cerebrospinal fluid production by caffeine consumption

Caffeine is the most commonly consumed psycho-stimulant in the world. The effects of caffeine on the body have been extensively studied; however, its effect on the structure of the brain has not been investigated to date.
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January 19, 2015 1:38 PM
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New Insights Into Antibody Overlap Syndromes | Neurology Times

New Insights Into Antibody Overlap Syndromes | Neurology Times | NeuroImmunology | Scoop.it
Be on the lookout for discordance in populations of patients with anti-NMDAR-syndrome, anti-AQP4 antibodies, and anti-MOG antibodies. Here's why.
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