NeuroImmunology
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Scooped by Gilbert C FAURE
October 12, 2015 7:03 AM
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Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain

Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain | NeuroImmunology | Scoop.it
Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain http://t.co/CXt00W2TQR
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Scooped by Gilbert C FAURE
October 11, 2015 12:15 PM
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ECTRIMS2015 - Multiple Sclerosis Progressive

Barcelona - ECTRIMS 2015 Opening Lecture by Prof Alan Thompson, Neurologist Progressive MS Aliance State of the art in Multiple Sclerosis Working in ...
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Scooped by Gilbert C FAURE
October 11, 2015 11:30 AM
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Acute bulbar, neck and limb weakness with monospecific anti-GT1a antibody: A rare localized subtype of Guillain-Barré sydnrome. - PubMed - NCBI

Muscle Nerve. 2015 Oct 9. doi: 10.1002/mus.24935. [Epub ahead of print]
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October 10, 2015 3:59 PM
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Meet Ocrelizumab, the drug that could revolutionize multiple sclerosis treatment - Nature World Report

Nature World Report
Meet Ocrelizumab, the drug that could revolutionize multiple sclerosis treatment
Nature World Report
The new drug may be able to help people suffering from multiple sclerosis live a normal life.
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Scooped by Gilbert C FAURE
October 9, 2015 3:27 PM
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Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression : Scientific Reports

Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression : Scientific Reports | NeuroImmunology | Scoop.it
Scientific Reports is an online, open access journal from the publishers of Nature. The 2014 Impact Factor for Scientific Reports is 5.578.
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Scooped by Gilbert C FAURE
October 9, 2015 3:24 PM
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Study of daclizumab yields mixed results in multiple sclerosis - Medical Xpress

Study of daclizumab yields mixed results in multiple sclerosis - Medical Xpress | NeuroImmunology | Scoop.it
(HealthDay)—Multiple sclerosis patients taking daclizumab high yield process (HYP), a humanized monoclonal antibody that binds to CD25 (alpha subunit of the interleukin-2 receptor) and modulates interleukin-2 signaling, ...
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Scooped by Gilbert C FAURE
October 8, 2015 10:26 AM
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Barriers Between Blood and CSF, Brain Yield to Aβ—Not a Bad Thing? | ALZFORUM

Barriers Between Blood and CSF, Brain Yield to Aβ—Not a Bad Thing? | ALZFORUM | NeuroImmunology | Scoop.it
The barrier between the blood and central nervous system crumbles in Alzheimer’s disease, but researchers have known little about how this happens, or what it does to brain pathology. Two new papers shed some light on how Aβ damages the cells that protect the brain parenchyma and cerebrospinal fluid. The studies examine different systems and describe distinct mechanisms, but both add to the picture of what may happen in disease.
Gilbert C FAURE's insight:

see serot et al 2000!

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Scooped by Gilbert C FAURE
October 7, 2015 8:47 AM
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Natalizumab analogon therapy is effective in a B cell-dependent multiple sclerosis model - Häusler - 2015 - Neuropathology and Applied Neurobiology - Wiley Online Library

Natalizumab analogon therapy is effective in a B cell-dependent multiple sclerosis model - Häusler - 2015 - Neuropathology and Applied Neurobiology - Wiley Online Library | NeuroImmunology | Scoop.it
Natalizumab analogon therapy is effective in a B cell-dependent multiple sclerosis model http://t.co/sJo2mkGbMQ http://t.co/isZEM93QMd
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Scooped by Gilbert C FAURE
October 6, 2015 1:46 PM
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Alzheimer's Research & Therapy | Full text | Cerebrospinal fluid levels of IL-6 are decreased and correlate with cognitive status in DLB patients

Inflammatory processes have previously been shown to influence cognition and progression of dementia.
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Scooped by Gilbert C FAURE
October 5, 2015 5:38 AM
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Calcitonin-gene related peptide antibody inhibition shows migraine prevention ... - News-Medical.net

Calcitonin-gene related peptide antibody inhibition shows migraine prevention ... - News-Medical.net | NeuroImmunology | Scoop.it
TEV-48125, a monoclonal anti-calcitonin-gene related peptide antibody, is well tolerated and effective in the prevention of high-frequency episodic migraine and chronic migraine, findings from two phase IIb studies show.
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Scooped by Gilbert C FAURE
October 3, 2015 8:04 AM
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Cerebral nitric oxide represses choroid plexus NFκB-dependent gateway activity for leukocyte trafficking. - PubMed - NCBI

EMBO J. 2015 Jul 2;34(13):1816-28. doi: 10.15252/embj.201591468. Epub 2015 May 4. Research Support, Non-U.S. Gov't
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Scooped by Gilbert C FAURE
October 1, 2015 3:24 PM
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The Very Intelligent Choroid Plexus Epithelial Cell - Linkis.com

The very intelligent choroid plexus epithelial cell not only produces the CSF, but also controls the window between the immune system and the brain.
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October 1, 2015 3:21 PM
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The Combined Performance of ADC, CSF CXC Chemokine Ligand 13, and CSF Interleukin 10 in the Diagnosis of Central Nervous System Lymphoma. - PubMed - NCBI

AJNR Am J Neuroradiol. 2015 Sep 17. [Epub ahead of print]
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October 11, 2015 12:20 PM
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Expression of DICAM on TH17 Lymphocytes Documented in Neuroinflammation - Neurology Advisor

Expression of DICAM on TH17 Lymphocytes Documented in Neuroinflammation - Neurology Advisor | NeuroImmunology | Scoop.it
DICAM was strongly linked with expression of ROR-γ, IL-23R, IL-17, IL-22, GM-CSF, and GZMB expression in human CD4+ lymphocytes.
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October 11, 2015 12:15 PM
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Thyroxine transfer from cerebrospinal fluid into choroid plexus and brain is affected by brefeldin A, low sodium, BCH, and phloretin, in ventriculo-cisternal perfused rabbits

Thyroxine (T4) hormone is synthesized by the thyroid gland and then released into the systemic circulation where it binds to a number of proteins.
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Scooped by Gilbert C FAURE
October 10, 2015 4:01 PM
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The effect of B-cell depletion in the Theiler's model of multiple sclerosis - Journal of the Neurological Sciences

RT @wfneurology: The effect of B-cell depletion in the Theiler's model of multiple sclerosis http://t.co/EL3S1UXJe4
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Scooped by Gilbert C FAURE
October 10, 2015 3:59 PM
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8,000 Participate in the Biggest Scientific Event On Multiple Sclerosis Held in Barcelona

8,000 Participate in the Biggest Scientific Event On Multiple Sclerosis Held in Barcelona | NeuroImmunology | Scoop.it
31st Congress of the European Committee for Treatment and Research in Multiple Sclerosis is designed to tackle the main topics for future MS management.
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Scooped by Gilbert C FAURE
October 9, 2015 3:27 PM
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William Sonstein M.D publishes a new paper on Cerebrospinal Fluid

William Sonstein M.D publishes a new paper on Cerebrospinal Fluid | NeuroImmunology | Scoop.it
Willian Sonstein, M.D. has published a new paper on cerebrospinal fluid in the journal Electrophoresis. You can see the paper here. Abstract: A simple and
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Scooped by Gilbert C FAURE
October 9, 2015 3:22 PM
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Gray matter–related proteins are associated with childhood-onset multiple sclerosis

Gray matter–related proteins are associated with childhood-onset multiple sclerosis | NeuroImmunology | Scoop.it
RT @GreenJournal: Gray matter–related proteins are associated with childhood-onset multiple sclerosis http://t.co/7oPKiWUNPZ #Neurology
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October 8, 2015 10:25 AM
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Targeting the Interleukin 6 Receptor to Treat Neuromyelitis Optica. - PubMed - NCBI

JAMA Neurol. 2015 Jul;72(7):747-8. doi: 10.1001/jamaneurol.2015.0579. Comment; Editorial; Research Support, Non-U.S. Gov't
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October 7, 2015 8:43 AM
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Identification of a Biomarker in Cerebrospinal Fluid for Neuronopathic Forms of Gaucher Disease

Identification of a Biomarker in Cerebrospinal Fluid for Neuronopathic Forms of Gaucher Disease | NeuroImmunology | Scoop.it
Identification of a Biomarker in Cerebrospinal Fluid for Neuronopathic Forms of Gaucher Disease http://t.co/dC68OWYT7i
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Scooped by Gilbert C FAURE
October 5, 2015 10:46 AM
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Association of interleukin-1 gene cluster polymorphisms and haplotypes with multiple sclerosis in an Iranian population

Association of interleukin-1 gene cluster polymorphisms and haplotypes with multiple sclerosis in an Iranian population | NeuroImmunology | Scoop.it
Association of interleukin-1 gene cluster polymorphisms & haplotypes with multiple sclerosis in an Iranian population http://t.co/B5MFFnsaVd
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Scooped by Gilbert C FAURE
October 3, 2015 8:05 AM
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Pilot Study of Natural Killer Cells in Chronic ...

Pilot Study of Natural Killer Cells in Chronic ... | NeuroImmunology | Scoop.it
RT @Vansteenwinckel: Pilot Study of Natural Killer Cells in CFS/ME and Multiple Sclerosis http://t.co/LqG6iyDPUd #mecfs #seid #ms Abstract Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME) and Multiple Sclerosis (MS) patients suffer from...
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Scooped by Gilbert C FAURE
October 3, 2015 8:03 AM
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The choroid plexus in health and disease - Harvard University

The choroid plexus in health and disease - Harvard University | NeuroImmunology | Scoop.it
The choroid plexus in health and disease by Martin G Netsky http://t.co/Us8IqiNGks
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Scooped by Gilbert C FAURE
October 1, 2015 3:22 PM
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Disruption of brain-blood barrier might influence progression of Alzheimer's ... - EurekAlert (press release)

Disruption of brain-blood barrier might influence progression of Alzheimer's ... - EurekAlert (press release) | NeuroImmunology | Scoop.it
More and more data from preclinical and clinical studies strengthen the hypothesis that immune system-mediated actions contribute to and drive pathogenesis in Alzheimer's disease.
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