Mucosal Immunity
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Mucosal Immunity
The largest immune tissue in the body
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Rescooped by Gilbert C FAURE from CME-CPD
August 18, 2015 5:29 AM
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Gut Microbiome

Don't miss out on the #Gut #Microbiome #CME Conference in #Huntington #Beach! http://t.co/6rTDbFa0kB #Gi http://t.co/zYsib9kUKI
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Scooped by Gilbert C FAURE
August 17, 2015 6:01 AM
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A novel protein-based subunit Shigella vaccine candidate - Nature.com

A novel protein-based subunit Shigella vaccine candidate - Nature.com | Mucosal Immunity | Scoop.it
Immunology and Cell Biology focuses on the general functioning of the immune system in its broadest sense, with a particular emphasis on its cell biology.
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Scooped by Gilbert C FAURE
August 17, 2015 6:00 AM
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Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: an open randomized controlled trial

Effect of nasal balloon autoinflation in children with otitis media with effusion in primary care: an open randomized controlled trial | Mucosal Immunity | Scoop.it
RT @CMAJ_News: Mechanism of autoinflation, found safe & effective in kids with secretory #otitismedia http://t.co/LXoCU4zTMS http://t.co/Nk…;
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Scooped by Gilbert C FAURE
August 17, 2015 5:59 AM
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Role of B Cells in Mucosal Vaccine–Induced Protective CD8+ T Cell Immunity against Pulmonary Tuberculosis

Role of B Cells in Mucosal Vaccine–Induced Protective CD8+ T Cell Immunity against Pulmonary #Tuberculosis http://t.co/Jx8O4ZzUjw
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Suggested by Société Francaise d'Immunologie
August 17, 2015 4:56 AM
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Indian cholera vaccine found to be safe, efficacious - The Hindu

Indian cholera vaccine found to be safe, efficacious - The Hindu | Mucosal Immunity | Scoop.it
The safety and efficacy of oral cholera vaccine Shanchol manufactured by the Hyderabad-based Shantha Biotechnics Private Limited, a Sanofi company, have been proved in a large-scale field trial involving 94,675 people i...
Gilbert C FAURE's insight:

At the end of two years of follow-up, people in the vaccine group who got one dose of the vaccine showed 37 per cent overall protection against severely dehydrating cholera. The level of protection increased to 53 per cent in those who got the full regimen of two vaccine doses given at an interval of at least 14 days.

Though the protection conferred is not very high, the 53 per cent protection can help save many lives in Bangladesh. There are nearly 300,000 cases and 4,500 cholera deaths every year in Bangladesh.

Surprisingly, the level of protection did increase greatly when vaccination was combined with hand washing. Only a modest 45 per cent protection was seen when one dose was administered to a group (over 92,500 people) that got the vaccine and behavioural change (hand washing). The level of protection shot up to 58 per cent when volunteers in this group received two vaccine doses.

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Scooped by Gilbert C FAURE
August 15, 2015 3:41 AM
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Revealed: Helicobacter pylori's secret weapon

Is the game up for Helicobactor pylori? Researchers have identified the molecular mechanism that the bacterium's best-known adhesion protein uses to attach to stomach sugars and evade the body's attempts to 'flush' it away.
Erika Nava's curator insight, August 16, 2015 12:39 AM

this is really interesting since many people suffer from gastric ulcers.

Scooped by Gilbert C FAURE
August 14, 2015 10:24 AM
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Systems Modeling of Interactions between Mucosal Immunity and the Gut Microbiome during Clostridium difficile Infection. - PubMed - NCBI

Systems Modeling of Interactions between Mucosal Immunity and the Gut Microbiome during Clostridium difficile Infection. - PubMed - NCBI | Mucosal Immunity | Scoop.it
PLoS One. 2015 Jul 31;10(7):e0134849. doi: 10.1371/journal.pone.0134849.
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Scooped by Gilbert C FAURE
August 14, 2015 8:09 AM
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Guest Post -- The Emergent Microbiome: A Revolution for the Life Sciences ... - JD Supra (press release)

This is the second article in a series on advancements in microbiome research and development. This installment reviews US patents issued in 2015 in "Microbiomics." Upcoming articles...
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Scooped by Gilbert C FAURE
August 9, 2015 4:37 AM
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Secretory leukocyte protease inhibitor inhibits expression of polymeric immunoglobulin receptor via the NF-κB signaling pathway. - PubMed - NCBI

Secretory leukocyte protease inhibitor inhibits expression of polymeric immunoglobulin receptor via the NF-κB signaling pathway. - PubMed - NCBI | Mucosal Immunity | Scoop.it
Mol Immunol. 2015 Jul 31. pii: S0161-5890(15)30029-8. doi: 10.1016/j.molimm.2015.07.021. [Epub ahead of print]
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Scooped by Gilbert C FAURE
August 6, 2015 6:21 AM
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Helicobacter pylori, HIV and Gastric Hypochlorhydria in the Malawian Population

Helicobacter pylori, HIV and Gastric Hypochlorhydria in the Malawian Population | Mucosal Immunity | Scoop.it
by Joe Geraghty, Alexander Thumbs, Anstead Kankwatira, Tim Andrews, Andrew Moore, Rose Malamba, Neema Mtunthama, Kai Hellberg, Lughano Kalongolera, Paul O’Toole, Andrea Varro, D.
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Scooped by Gilbert C FAURE
July 30, 2015 3:23 PM
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Regulatory T-cell depletion in the gut caused by integrin β7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity

Regulatory T-cell depletion in the gut caused by integrin β7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity | Mucosal Immunity | Scoop.it
Allergy/Immunology Article: Regulatory T-cell depletion in the gut caused by integrin β7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity
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Scooped by Gilbert C FAURE
July 28, 2015 8:23 AM
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A new monoclonal antibody for detecting degalactosylated IgA1 as serum biomarker of IgA nephropathy

A new monoclonal antibody for detecting degalactosylated IgA1 as serum biomarker of IgA nephropathy | Mucosal Immunity | Scoop.it
"A new monoclonal antibody for detecting degalactosylated IgA1 as serum biomarker of IgA nephropathy" #nephrology http://t.co/FRVdvzuGgj
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Scooped by Gilbert C FAURE
July 27, 2015 3:41 AM
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Experimental & Molecular Medicine - Acute exposure to silica nanoparticles ... - Nature.com

Experimental & Molecular Medicine - Acute exposure to silica nanoparticles ... - Nature.com | Mucosal Immunity | Scoop.it
Experimental & Molecular Medicine is an open access journal that publishes the highest quality articles in translational research and biomedical studies.
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Scooped by Gilbert C FAURE
August 17, 2015 6:25 AM
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The Gut Microbiota of Wild Mice

The Gut Microbiota of Wild Mice | Mucosal Immunity | Scoop.it
by Laura Weldon, Stephen Abolins, Luca Lenzi, Christian Bourne, Eleanor M. Riley, Mark Viney
The gut microbiota profoundly affects the biology of its host.
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Scooped by Gilbert C FAURE
August 17, 2015 6:00 AM
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Biliary tract: Solving the conundrum of cholangiocyte differentiation : Nature ... - Nature.com

Biliary tract: Solving the conundrum of cholangiocyte differentiation : Nature ...
Gilbert C FAURE's insight:

epithelial cells

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Scooped by Gilbert C FAURE
August 17, 2015 6:00 AM
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The Role of Mucosal Associated Invariant T Cells in Antimicrobial Immunity. - PubMed - NCBI

Front Immunol. 2015 Jul 6;6:344. doi: 10.3389/fimmu.2015.00344. eCollection 2015. Review
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Suggested by Société Francaise d'Immunologie
August 17, 2015 4:56 AM
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IL-17-Mediated Immunity to the Opportunistic Fungal Pathogen Candida albicans [BRIEF REVIEWS]

IL-17 (IL-17A) has emerged as a key mediator of protection against extracellular microbes, but this cytokine also drives pathology in various autoimmune diseases.
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Rescooped by Gilbert C FAURE from NeuroImmunology
August 17, 2015 4:51 AM
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Work towards a goal, not a pay cheque - The Hindu

Work towards a goal, not a pay cheque - The Hindu | Mucosal Immunity | Scoop.it
The world of neuroscience is far removed from most of us — a world of big words and bigger ideas that occupy the minds of specialists and scientists in rooms far away from our own.
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Scooped by Gilbert C FAURE
August 14, 2015 10:25 AM
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Distinct Murine Mucosal Langerhans Cell Subsets Develop from Pre-dendritic Cells and Monocytes: Immunity

Distinct Murine Mucosal Langerhans Cell Subsets Develop from Pre-dendritic Cells and Monocytes: Immunity | Mucosal Immunity | Scoop.it
RT @ImmunityCP: Where do mucosal langerhans cells come from? Hovav lab has the answers http://t.co/OLEyQm78Yh http://t.co/FpMR8VxUMM
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Scooped by Gilbert C FAURE
August 14, 2015 9:48 AM
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Antibiotic Exposure and Other Risk Factors for Antimicrobial Resistance in Nasal Commensal Staphylococcus aureus: An Ecological Study in 8 European Countries

Antibiotic Exposure and Other Risk Factors for Antimicrobial Resistance in Nasal Commensal Staphylococcus aureus: An Ecological Study in 8 European Countries | Mucosal Immunity | Scoop.it
by Evelien M. E. van Bijnen, John Paget, Elly S. M. de Lange-de Klerk, Casper D. J. den Heijer, Ann Versporten, Ellen E. Stobberingh, Herman Goossens, François G.
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Scooped by Gilbert C FAURE
August 10, 2015 6:56 AM
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Germs and joints: the contribution of the human microbiome to rheumatoid arthritis - Nature.com

Nature.com Germs and joints: the contribution of the human microbiome to rheumatoid arthritis Nature.com Whereas the mucosal surface of the gut offers arguably the greatest potential for host-microbe interactions, almost all mucosae have resident...
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Scooped by Gilbert C FAURE
August 9, 2015 4:26 AM
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Frequent High Expression of Kita-Kyushu Lung Cancer Antigen-1 (KK-LC-1) in Gastric Cancer. - PubMed - NCBI

Frequent High Expression of Kita-Kyushu Lung Cancer Antigen-1 (KK-LC-1) in Gastric Cancer. - PubMed - NCBI | Mucosal Immunity | Scoop.it
Anticancer Res. 2015 Jun;35(6):3575-9. Research Support, Non-U.S. Gov't
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Scooped by Gilbert C FAURE
August 6, 2015 6:10 AM
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γδ Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice. - PubMed - NCBI

γδ Intraepithelial Lymphocyte Migration Limits Transepithelial Pathogen Invasion and Systemic Disease in Mice. - PubMed - NCBI | Mucosal Immunity | Scoop.it
Gastroenterology. 2015 Jun;148(7):1417-26. doi: 10.1053/j.gastro.2015.02.053. Epub 2015 Mar 4. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Video-Audio Media
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Suggested by Société Francaise d'Immunologie
July 28, 2015 8:45 AM
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Interleukin-12 and -23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria. - PubMed - NCBI

Interleukin-12 and -23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria. - PubMed - NCBI | Mucosal Immunity | Scoop.it
Immunity. 2015 Jul 13. pii: S1074-7613(15)00263-0. doi: 10.1016/j.immuni.2015.06.019. [Epub ahead of print]
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Scooped by Gilbert C FAURE
July 27, 2015 2:44 PM
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Dcs tailor T cells to the tissue - Nature.com

Dcs tailor T cells to the tissue
Nature.com
This seminal study published in 2005 by William Agace and colleagues marked an important step forward in our understanding of mucosal immunology and dendritic cell (DC) biology.
Gilbert C FAURE's insight:

A Mowat, 2005

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