I will question the usefulness of MVC (MVC as in todays MV* implementations in JS frontend frameworks), the most established design pattern in frontend development. Let me make it clear that it is not my intention to invalidate MVC in general. Rather, I think it's importance as a design pattern for very interactive web applications is overstated.
This post here is ballsy, since MVC is baked into the heads of frontend people. It's ubiquitous. It's the biggest consensus amongst devs I've ever seen, and MVC is widely considered "best practice". Basically, people don't question MVC anymore. However, I personally think the concept doesn't apply optimally to complex web apps (I might be wrong though).
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Flux is mentioned here for solving communication between components:
https://github.com/facebook/react/tree/master/examples/todomvc-flux