Immunology
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Teaching and Learning Immunology. Information you never would have searched for!
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Scooped by Gilbert C FAURE
September 25, 2011 2:12 PM
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{gamma}-Interferon-regulated chaperone governs human... [FASEB J. 2011] - PubMed - NCBI

PubMed comprises more than 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
September 25, 2011 2:09 PM
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Human leukocyte antigen I knockdown human embryonic stem cells ...

Human leukocyte antigen I knockdown human embryonic stem cells induce host ignorance and achieve prolonged xenogeneic survival. Circulation. 2011 Sep 13;124(11 Suppl):S3-9. Authors: Deuse T, Seifert M, Phillips N, ...
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Scooped by Gilbert C FAURE
September 22, 2011 11:08 AM
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Ruslan Medzhitov Elected to National Academy of Sciences for Work on Innate Immunity | Universities and colleges online information... Universities Now!

Ruslan Medzhitov Elected to National Academy of Sciences for Work on Innate Immunity | Universities and colleges online information... Universities Now! | Immunology | Scoop.it
Ruslan Medzhitov Elected to National Academy of Sciences for Work on Innate Immunity, Universities Now allows you to have the latest information of the best univesities of the world...
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Scooped by Gilbert C FAURE
September 21, 2011 3:52 AM
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T Cell Dynamics during Induction of Tolerance and Suppression of ...

The results indicate that tolerance takes place in lymphoid organs, and surprisingly, the T cells do not become anergic but instead have a Th2 phenotype. The tolerant Th2 cells displayed reduced motility after tolerogen ...
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Scooped by Gilbert C FAURE
September 20, 2011 2:22 PM
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Current Topics in Innate Immunity II

Current Topics in Innate Immunity II | Immunology | Scoop.it
Mounting evidence in the past decade indicates that innate immunity mediates functions above and beyond first-line defense against infection. It is now appreciated that innate immune mechanisms are critically involved in the ...
Gilbert C FAURE's insight:
Summary of latest Aegean Conferences meeting - the 7th Innate Immunity ConferenceBrings together findings of international scientists with different advanced perspectivesDiscusses Evolution of the Innate Immune System, Host-pathogen interactions, and interactions with adaptive immunity.....  in the development of adaptive immunity and, moreover, the regulation of diverse physiological and homeostatic processes. The latter explains why deregulation of innate immunity may lead to pathological disorders that are not necessarily or directly related to host defense. This Volume compiles the latest advances in this rapidly evolving field as presented by eminent scientists at the 7th International Aegean Conference on Innate Immunity in Rhodes, Greece. It includes topics related to the biology and function of Toll-like and other pattern-recognition receptors, complement and its crosstalk with other physiological systems, inflammatory mechanisms and diseases, natural killer cells, and the cooperative interplay between innate and adaptive immune cells. This book is an excellent source of information for researchers and clinicians with interests in immunology, host-microbe interactions, and infectious and inflammatory diseases.
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Scooped by Gilbert C FAURE
September 19, 2011 11:08 AM
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Ibalizumab Study Casts a Ray of Hope for HIV-Positive People With Extensive Drug Resistance

Ibalizumab Study Casts a Ray of Hope for HIV-Positive People With Extensive Drug Resistance | Immunology | Scoop.it
Ibalizumab Study Casts a Ray of Hope for HIV-Positive People With Extensive Drug Resistance, at The Body PRO, the HIV/AIDS resource for health care professionals.
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Scooped by Gilbert C FAURE
September 16, 2011 9:53 AM
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Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are ...

Innate lymphoid cells (ILCs) are emerging as a family of effectors and regulators of innate immunity and tissue remodeling. Interleukin 22 (IL-22)- and IL-17-producing ILCs, which depend on the transcription factor RORγt, ...
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Scooped by Gilbert C FAURE
September 15, 2011 3:43 AM
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The Glow-In-The-Dark Kitty | Surprising Science

The Glow-In-The-Dark Kitty | Surprising Science | Immunology | Scoop.it
That the protection gene is expressed in the cat lymphoid organs, where AIDS virus spread and cell death mostly play out, is encouraging to us, however.” The ultimate goal of this line of research, though, is to figure out how to ...
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Scooped by Gilbert C FAURE
September 13, 2011 4:37 AM
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Amazon.co.jp: Theodyssey: The Pulsating Voyage & Adventures of White Blood Cell (A Theo T-Lymphocyte story): Caspian Ashworth, Neil Ashworth: 洋書

Amazon.co.jp: Theodyssey: The Pulsating Voyage & Adventures of White Blood Cell (A Theo T-Lymphocyte story): Caspian Ashworth, Neil Ashworth: 洋書 (Theodyssey: The Pulsating Voyage & Adventures of White Blood Cell (A Theo T-Lymphocyte story):
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Scooped by Gilbert C FAURE
September 13, 2011 4:34 AM
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Regulation of antigen-expressing dendritic cells by double negative regulatory T cells - Gao - 2011 - European Journal of Immunology - Wiley Online Library

Regulation of antigen-expressing dendritic cells by double negative regulatory T cells - Gao - 2011 - European Journal of Immunology - Wiley Online Library | Immunology | Scoop.it
Regulation of antigen-expressing dendritic cells by double negative regulatory T cells http://t.co/PbjUKhR #EJITCB...
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Abstract

TCRαβ+CD3+CD4−CD8−NK1.1− double negative (DN) Tregs comprise 1–3% of peripheral T lymphocytes in mice and humans. It has been demonstrated that DN Tregs can suppress allo-, xeno- and auto-immune responses in an Ag-specific fashion. However, the mechanisms by which DN Tregs regulate immune responses remain elusive. Whether DN Tregs can regulate DCs has not been investigated previously. In this study, we demonstrate that DN Tregs express a high level of CTLA4 and are able to down-regulate costimulatory molecules CD80 and CD86 expressed on Ag-expressing mature DCs (mDCs). DN Tregs from CTLA4 KO mice were not able to downregulate CD80 and CD86 expression, indicating that CTLA4 is critical for DN Treg-mediated downregulation of costimulatory molecule expression on Ag-expressing mature DCs. Furthermore, DN Tregs could kill both immature and mature allogeneic DCs, as well as Ag-loaded syngeneic DCs, in an Ag-specific manner in vitro and in vivo, mainly through the Fas-FasL pathway. These data demonstrate, for the first time, that DN Tregs are potent regulators of DCs and may have the potential to be developed as a novel immune suppression treatment.

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Scooped by Gilbert C FAURE
September 11, 2011 3:36 AM
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UF Researchers Find Chemical Signals that Initiate the Body's Immune Response - MD News (press release)

UF Researchers Find Chemical Signals that Initiate the Body's Immune Response - MD News (press release) | Immunology | Scoop.it
MD News (press release)UF Researchers Find Chemical Signals that Initiate the Body's Immune ResponseMD News (press release)The innate immune response is more generic and wasn't thought to convey any long-lasting immunity to specific threats.
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Scooped by Gilbert C FAURE
September 10, 2011 3:45 PM
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Adipose tissue innate immunity & inflammation - a nutrigenomics per...

Adipose tissue, innate immunity and inflammation – a nutrigenomics perspective of the metabolic syndrome Lecture in Scheveningen 2 Sept 2011 (RT @nutrigenomics: Bonus upload: Adipose tissue innate immunity & inflammation: a nutrigenomics perspective...
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Scooped by Gilbert C FAURE
September 10, 2011 3:37 PM
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Tollip: a multitasking protein in innate immunity and protein trafficking - Life Sciences Social Network

Tollip: a multitasking protein in innate immunity and protein trafficking - Life Sciences Social Network | Immunology | Scoop.it
Tollip: a multitasking protein in innate immunity and protein trafficking (Tollip: a multitasking protein in innate immunity and protein trafficking http://t.co/60V6r9y...)...
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Scooped by Gilbert C FAURE
September 25, 2011 2:11 PM
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Cancer study boosts hopes for Roche's armed antibody | Reuters

Cancer study boosts hopes for Roche's armed antibody | Reuters | Immunology | Scoop.it
STOCKHOLM (Reuters) - Women with an aggressive type of advanced breast cancer can live significantly longer without their disease getting worse if they are treated with an experimental armed antibody drug (Cancer study boosts hopes for Roche's armed...
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Scooped by Gilbert C FAURE
September 22, 2011 11:11 AM
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Amazon.com: Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity eBook: C. Jane Welsh, Mary Meagher, Esther Sternberg: Kindle Store

Amazon.com: Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity eBook: C.
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Scooped by Gilbert C FAURE
September 21, 2011 3:52 AM
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Million Dollar Shaw Prize Awarded For Cosmology, Immunology ...

Million Dollar Shaw Prize Awarded For Cosmology, Immunology ... | Immunology | Scoop.it
The Shaw Prize Foundation has awarded seven scientists the 2011 Shaw Prize for their pioneering work on gamma ray bursts, innate immunity, and modern geometry and physics.
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Scooped by Gilbert C FAURE
September 20, 2011 2:23 PM
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Handbook of Kidney Transplantation 5th edition | Free PDF Ebook ...

Type=chm Size=31.2MB Published=2010 Code: http://www./file/1984439834/B659_HBKT5.rar.
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September 20, 2011 2:16 PM
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Changes of monocyte human leukocyte antigen-DR expression as a reliable predictor of mortality in severe sepsis

{BioMed Central via BioPortfolio} IntroductionMany studies have shown that monocyte human leukocyte antigen-DR (mHLA-DR) expression may be a good predictor for...
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Scooped by Gilbert C FAURE
September 18, 2011 9:38 AM
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Insect Immunology Part 1

Insect Immunology Part 1 | Immunology | Scoop.it
In 1989, Charles A. Janeway first proposed the basic concept of innate immunity as the first-line host defense responses that serve to limit infection in the early hours after exposure to microorganisms (Janeway, 1989).
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Scooped by Gilbert C FAURE
September 15, 2011 3:44 AM
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Effect of rituximab on human in vivo antibody immune responses ...

OBJECTIVES: The effect of rituximab on in vivo antibody responses, particularly during the period of B-lymphocyte depletion, is incompletely determined. This study was designed to assess this knowledge void.
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Scooped by Gilbert C FAURE
September 15, 2011 3:25 AM
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A CCR4 antagonist combined with vaccines induce antigen-specific ...

A CCR4 antagonist combined with vaccines induce antigen-specific CD8+ T cells and tumor immunity against self antigens. Blood. 2011 Sep 9;. Authors: Pere H, Montier Y, Bayry J, Quintin-Colonna F, Merillon N, Dransart E, ...
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September 13, 2011 4:35 AM
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CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell–associated antigen

CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen http://t.co/f6CoCwQ #JEMTCB...
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Scooped by Gilbert C FAURE
September 12, 2011 6:23 AM
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Mapping a Dynamic Innate Immunity Protein Interaction Network ...

To systematically investigate innate immune signaling networks regulating production of type I interferon, we analyzed protein complexes formed after microbial recognition. Fifty-eight baits were associated with 260 interacting ...
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Scooped by Gilbert C FAURE
September 10, 2011 3:49 PM
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Circulating Endothelial Progenitor Cells in Kidney Transplant ...

Kidney transplantation (RTx) leads to amelioration of endothelial function in patients with advanced renal failure. Endothelial progenitor cells (EPCs) may play a key role in this repair process. The aim of this study was to ...
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Scooped by Gilbert C FAURE
September 10, 2011 3:38 PM
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PD-1 and Autoimmunity. « Medicine JournalFeeds

This review focuses primarily on PD-1 and its ligands, which form a crucial inhibitory costimulatory pathway for maintaining peripheral tolerance, and their contribution to autoimmunity. Since 1992, when PD-1 was isolated, ...
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