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Scooped by
Gilbert C FAURE
February 21, 3:58 AM
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Gilbert C FAURE
February 19, 8:46 AM
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In a recent study published in Nature, our scientists discovered that IL-27 — an important signaling protein that regulates immune responses — can boost the… | 27 comments on LinkedIn
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Gilbert C FAURE
February 10, 1:25 PM
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Gilbert C FAURE
February 7, 1:19 PM
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Several top editors of the Journal of Clinical Immunology, a Springer Nature title, have jumped ship to start a new, nonprofit journal with Rockefeller University Press. Jean-Laurent Casanova…
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Gilbert C FAURE
February 6, 1:31 PM
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Gilbert C FAURE
February 5, 12:50 PM
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Gilbert C FAURE
February 5, 3:46 AM
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Strong binding and potent neutralization by SARS-CoV or SARS-CoV-2 reactive mAbs. We used PBMCs of a SARS-CoV donor to isolate mAbs that bind RBD or NTD and cross neutralize SARS-CoV and SARS-CoV-2. We chose a human hybridoma approach, collected PBMCs from an individual about a decade after...
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Gilbert C FAURE
February 1, 1:37 PM
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Scooped by
Gilbert C FAURE
February 1, 7:32 AM
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Scooped by
Gilbert C FAURE
January 29, 5:57 AM
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Scooped by
Gilbert C FAURE
January 16, 4:13 AM
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𝗧-𝗰𝗲𝗹𝗹 𝗹𝘆𝘀𝗶𝘀 is a process by which cytotoxic T cells recognize and kill other cells, such as infected or tumor cells. Recognition is mediated by the…
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Gilbert C FAURE
January 14, 3:50 AM
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Our team at ScholarRx is pleased to announce a comprehensive update to our Immunology collection in Rx Bricks, reflecting the latest advances in medical…
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Gilbert C FAURE
January 9, 11:11 AM
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The IEI Committee consists of experts in all aspects of primary immunodeficiencies.
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Gilbert C FAURE
February 19, 8:48 AM
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Gilbert C FAURE
February 15, 5:04 AM
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Gilbert C FAURE
February 10, 7:15 AM
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Gilbert C FAURE
February 7, 7:35 AM
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B cells have long been understood to be drivers of both humoral and cellular immunity. Recent advances underscore this importance but also indicate that in infection, inflammatory disease and cancer, B cells function directly at sites of inflammation and form tissue-resident memory populations. The spatial organization and cellular niches of tissue B cells have profound effects on their function and on disease outcome, as well as on patient response to therapy. Here we review the role of B cells in peripheral tissues in homeostasis and disease, and discuss the newly identified cellular and molecular signals that are involved in regulating their activity. We integrate emerging data from multi-omic human studies with experimental models to propose a framework for B cell function in tissue inflammation and homeostasis. B cells are major drivers of systemic immunity, but they also act locally in non-lymphoid organs. This Review highlights new insights into mechanisms of tissue B cell function as well as efforts to leverage this biology for immunotherapy.
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Gilbert C FAURE
February 6, 6:01 AM
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Gilbert C FAURE
February 5, 4:42 AM
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𝐅𝐨𝐮𝐫 𝐥𝐞𝐬𝐬𝐨𝐧𝐬 𝐂𝐎𝐕𝐈𝐃 𝐭𝐚𝐮𝐠𝐡𝐭 𝐮𝐬 𝐚𝐛𝐨𝐮𝐭 𝐭𝐡𝐞 𝐢𝐦𝐦𝐮𝐧𝐞 𝐬𝐲𝐬𝐭𝐞𝐦, 𝐧𝐚𝐭𝐮𝐫𝐞 𝐍𝐄𝐖𝐒📋
✅The COVID-19 pandemic has revealed…
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Gilbert C FAURE
February 3, 9:44 AM
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Kidney diseases are widespread and represent a considerable medical, social and economic burden. However, there has been marked progress in understanding the immunological aspects of kidney disease. This includes the identification of distinct intrarenal immunological niches and characterization of kidney disease endotypes according to the underlying molecular immunopathology, as well as a better understanding of the pathological roles for T cells, mononuclear phagocytes and B cells and the renal elements they target. These insights have improved the diagnosis of kidney disease. Here, we discuss new developments in our understanding of kidney immunology, focusing on immune mechanisms of disease and their translational implications for the diagnosis and treatment of kidney disease. We also describe the immune-mediated crosstalk between the kidney and other organs that influences kidney disease and extrarenal inflammation. Kidney diseases affect millions globally. Advances in understanding immunological mechanisms and disease endotypes have enhanced diagnostic accuracy and treatment strategies. Here, the authors review our current understanding of immune mechanisms of kidney disease and highlight the interplay between renal and systemic immunity.
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Gilbert C FAURE
February 1, 11:27 AM
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Recent research published in Frontiers in Immunology (PMID: 38979417) demonstrated that acute moderate-intensity exercise induces significant mobilization of…
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Gilbert C FAURE
February 1, 5:22 AM
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New #Cytotoxic #Bcells Discovered in Breaking Nature #Immunology Study | Integrated #scRNAseq & #TCR / #BCR Sequencing with #MassCytometry of Human Peripheral…
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Gilbert C FAURE
January 29, 3:42 AM
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Scooped by
Gilbert C FAURE
January 14, 1:50 PM
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Scientists from Duke-NUS Medical School and the Singapore General Hospital have discovered that #T cells - white blood cells that can destroy harmful…
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Gilbert C FAURE
January 12, 3:33 AM
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#Inflammation | #Autoimmunity | #SARSCoV2 - the #Virus that keeps on giving | Identification of a #Spike-derived #Peptide with #SuperAntigen-like properties…
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