AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
January 25, 2014 7:38 AM
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TNF Receptor 2 and Disease: Autoimmunity and Regenerative Medicine

Exciting...just released: TNF Receptor 2 and Disease: Autoimmunity and Regenerative Medicine. http://t.co/b7fcOlecRE
Gilbert C FAURE's insight:

frontiers in autoimmunity

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Scooped by Gilbert C FAURE
January 25, 2014 7:36 AM
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Autoimmune Complications after Hematopoietic Stem Cell ...

Autoimmune Complications after Hematopoietic Stem Cell ... | AUTOIMMUNITY | Scoop.it
However, none had autoimmune markers such as anti-nuclear antibodies (ANA), antismooth muscle, and scleroderma (Scl-70) antibody. Histological examination was necessary to make the diagnosis in three patients, which ...
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Scooped by Gilbert C FAURE
January 24, 2014 1:26 PM
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STELARA®* (Ustekinumab) Receives Health Canada Approval for Treatment of ... - DigitalJournal.com

STELARA®* (Ustekinumab) Receives Health Canada Approval for Treatment of ...
Gilbert C FAURE's insight:

psoriasis

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Rescooped by Gilbert C FAURE from NeuroImmunology
January 24, 2014 10:33 AM
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PLOS ONE: Development of Central Nervous System Autoimmunity Is Impaired in the Absence of Wiskott-Aldrich Syndrome Protein

PLOS ONE: Development of Central Nervous System Autoimmunity Is Impaired in the Absence of Wiskott-Aldrich Syndrome Protein | AUTOIMMUNITY | Scoop.it
PLOS ONE: an inclusive, peer-reviewed, open-access resource from the PUBLIC LIBRARY OF SCIENCE. Reports of well-performed scientific studies from all disciplines freely available to the whole world.
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Scooped by Gilbert C FAURE
January 23, 2014 11:08 AM
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Giantin is the Major Golgi Autoantigen in Human Anti-Golgi

Giantin is the Major Golgi Autoantigen in Human Anti-Golgi | AUTOIMMUNITY | Scoop.it
The Golgi complex is an elaborate cytoplasmic organelle that has a prominent function in the processing, transporting, and sorting of intracellular proteins subsequent to their synthesis in the rough endoplasmic reticulum.
Gilbert C FAURE's insight:

got one scleroderma and sjogren's patient with very unusual triple substrate pattern and difficult to resolve, mearly misleading aspect on HEP-2 associating centromeric and Golgi labelling.

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Scooped by Gilbert C FAURE
January 22, 2014 3:13 PM
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Autoantibodies may help detect early-stage esophageal squamous cell carcinoma - Healio

Autoantibodies may help detect early-stage esophageal squamous cell carcinoma - Healio | AUTOIMMUNITY | Scoop.it
Autoantibodies may help detect early-stage esophageal squamous cell carcinoma Healio Physicians may be able to accurately diagnose the eighth most common malignant disease and the sixth leading cause of cancer-related death worldwide in its early...
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Scooped by Gilbert C FAURE
January 21, 2014 5:39 AM
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Autoimmunity Conference - Nice, France | 26-30 March, 2014

Autoimmunity Conference - Nice, France | 26-30 March, 2014 | AUTOIMMUNITY | Scoop.it
The 9th International Congress on Autoimmunity will take place in Nice, France, from 26-30 March, 2014.
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Scooped by Gilbert C FAURE
January 20, 2014 2:30 PM
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Systematic review and meta-analysis of the sero-epidemiological association ... - ProHealth

Systematic review and meta-analysis of the sero-epidemiological association ... - ProHealth | AUTOIMMUNITY | Scoop.it
Systematic review and meta-analysis of the sero-epidemiological association ...
ProHealth
Quality assessment found most studies reported acceptable selection criteria but poor description of how cases and controls were recruited.
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Suggested by Société Francaise d'Immunologie
January 20, 2014 5:13 AM
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Requirement for MyD88 Signaling in B Cells and Dendritic Cells for Germinal Center Anti-Nuclear Antibody Production in Lyn-Deficient Mice [AUTOIMMUNITY]

Requirement for MyD88 Signaling in B Cells and Dendritic Cells for Germinal Center Anti-Nuclear Antibody Production in Lyn-Deficient Mice [AUTOIMMUNITY] | AUTOIMMUNITY | Scoop.it
The intracellular tyrosine kinase Lyn mediates inhibitory receptor function in B cells and myeloid cells, and Lyn–/– mice spontaneously develop an autoimmune and inflammatory disease that closely resembles human systemic lupus erythematosus.
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Scooped by Gilbert C FAURE
January 19, 2014 5:21 AM
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The Microbiome, Autoimmunity, and Arthritis: Cause and Effect: An Historical Perspective

The Microbiome, Autoimmunity, and Arthritis: Cause and Effect: An Historical Perspective | AUTOIMMUNITY | Scoop.it
RT @wholefammd: The #microbiome, #arthritis, and #autoimmunity http://t.co/4tW3BVOR3c
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Scooped by Gilbert C FAURE
January 18, 2014 6:59 AM
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New Genetic Clue to Lupus Is Found - Scientific American

Scientific American
New Genetic Clue to Lupus Is Found
Scientific American
In many autoimmune disorders antibodies run amok, targeting not invading microbes, but a person's organs.
Gilbert C FAURE's insight:

Fc gamma RII

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Scooped by Gilbert C FAURE
January 18, 2014 2:59 AM
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Autoimmunity in the pathogenesis and... [Curr Allergy Asthma Rep. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:

dry eye...

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Scooped by Gilbert C FAURE
January 16, 2014 7:35 AM
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Doubled prevalence rates of ANCA-associated vasculitides and giant cell arteritis between 1994 and 2006 in northern Germany

Doubled prevalence rates of ANCA-associated vasculitides and giant cell arteritis between 1994 and 2006 in northern Germany | AUTOIMMUNITY | Scoop.it
Looking like an epidemic of vasculitis in Germany... http://t.co/JAmFe9QlWt
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Scooped by Gilbert C FAURE
January 25, 2014 7:37 AM
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Antiphospholipid Antibodies – Cause of Autoimmune Disease?

Antiphospholipid Antibodies – Cause of Autoimmune Disease? | AUTOIMMUNITY | Scoop.it
Reviewer: Jacinta G. Barr Product Reviewed: Antiphospholipid Antibodies Rating: Antiphospholipid antibodies (or APA) are a type.
Gilbert C FAURE's insight:

for laypeople

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Scooped by Gilbert C FAURE
January 25, 2014 7:36 AM
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Autoantibody Testing on ADVANCE for Administrators of the Laboratory

Autoantibody Testing on ADVANCE for Administrators of the Laboratory | AUTOIMMUNITY | Scoop.it
Trending overuse of these assays makes patients sick and costs rise (#Autoantibody Testing:Trending overuse of assays makes patients sick and costs rise http://t.co/x5fscnSq5x)...
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Rescooped by Gilbert C FAURE from Type 1 diabetes
January 24, 2014 1:14 PM
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Low HERV-K(C4) Copy Number is Associated with Type 1 Diabetes

Here we investigate the relationship between C4 variation/copy number and type 1 diabetes. We find that individuals with type 1 diabetes have significantly fewer copies of HERV-K(C4), and that this effect is not solely due to ...

Via Remi Creusot
Remi Creusot's curator insight, January 24, 2014 12:45 PM

An integrated retroviral element protective against T1D? One of the most peculiar genetic associations I have seen so far...

Scooped by Gilbert C FAURE
January 24, 2014 10:32 AM
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Frontiers | Pathogenesis of autoimmunity in common variable immunodeficiency | Frontiers in Primary Immunodeficiencies

Common variable immunodeficiency (CVID) presents in up to 25% of patients with autoimmune (AI) manifestations. Given the frequency and early onset in patients with CVID, AI dysregulation seems to be an integral part of the immunodeficiency.
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Scooped by Gilbert C FAURE
January 22, 2014 3:14 PM
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Vitamin D deficiency may be a risk factor for recurrent pregnancy losses by increasing cellular immunity and autoimmunity

Vitamin D deficiency may be a risk factor for recurrent pregnancy losses by increasing cellular immunity and autoimmunity | AUTOIMMUNITY | Scoop.it
Vit D deficiency may be a risk factor for recurrent pregnancy losses by increasing cellular immunity and autoimmunity http://t.co/lYn0Vm4Hje
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Scooped by Gilbert C FAURE
January 21, 2014 1:45 PM
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Tissue transglutaminase antibody levels predi... [Arch Dis Child. 2013] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Scooped by Gilbert C FAURE
January 21, 2014 5:37 AM
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Microbiome and mucosal inflammation as e... [Curr Opin Rheumatol. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Société Francaise d'Immunologie's comment, April 28, 2014 9:51 AM
Emerging data implicate the microbiome in RA pathogenesis. Mucosal sites exposed to a high load of bacterial antigens--such as the periodontium, lung, and gut--may represent the initial site of autoimmune generation. If validated, these findings could lead to the discovery of potential biomarkers and therapeutic approaches in the preclinical and clinical phases of RA.
Scooped by Gilbert C FAURE
January 20, 2014 5:14 AM
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Diagnostic accuracy of blood B-cell subse... [Arthritis Res Ther. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:

the brest group pursue the sjögren projects

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Suggested by Société Francaise d'Immunologie
January 20, 2014 5:12 AM
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Follicular B Cells in Thyroids of Mice with Spontaneous Autoimmune Thyroiditis Contribute to Disease Pathogenesis and Are Targets of Anti-CD20 Antibody Therapy [AUTOIMMUNITY]

Follicular B Cells in Thyroids of Mice with Spontaneous Autoimmune Thyroiditis Contribute to Disease Pathogenesis and Are Targets of Anti-CD20 Antibody Therapy [AUTOIMMUNITY] | AUTOIMMUNITY | Scoop.it
B cells are required for development of spontaneous autoimmune thyroiditis (SAT) in NOD.H-2h4 mice where they function as important APCs for activation of CD4+ T cells. Depletion of B cells using anti-CD20 effectively inhibits SAT development.
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Scooped by Gilbert C FAURE
January 18, 2014 2:21 PM
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Cancer immunosurveillance gone awry? | The Immuno Blog

Cancer immunosurveillance gone awry? | The Immuno Blog | AUTOIMMUNITY | Scoop.it
The potential relationship between cancer and autoimmunity is intriguing. Patients with certain autoimmune rheumatic diseases are known to have an increased risk of developing certain malignancies. ...
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Scooped by Gilbert C FAURE
January 18, 2014 3:21 AM
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Clinical parameter and Th17 related to lymphocytes infiltrating degree of labial salivary gland in primary Sjögrens syndrome

Clinical parameter and Th17 related to lymphocytes infiltrating degree of labial salivary gland in primary Sjögrens syndrome | AUTOIMMUNITY | Scoop.it
Rheumatology Medical Article: Clinical parameter and Th17 related to lymphocytes infiltrating degree of labial salivary gland in primary Sjögrens syndrome (Clinical parameter and Th17 related to lymphocytes infiltrating degree of labial salivary...
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Scooped by Gilbert C FAURE
January 17, 2014 7:33 AM
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Autoantibody-Mediated Bone Loss. [Curr Osteoporos Rep. 2014] - PubMed - NCBI

PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:

bone and autoimmunity, a new kid on the block

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