Virology News
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Virology News
Topical news snippets about viruses that affect people.  And other things. Like Led Zeppelin. And zombies B-)
Curated by Ed Rybicki
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GlaxoSmithKline steps in to fund flu vaccine program

GlaxoSmithKline steps in to fund flu vaccine program | Virology News | Scoop.it
A pharmaceutical giant is picking up the federal government's slack in funding a program aimed at curbing flu infections.

 

...and will inevitably own it....

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A Promising Trial HIV vaccine in Canada

A Promising Trial HIV vaccine in Canada | Virology News | Scoop.it
While an estimated 30 HIV vaccines are being tested around the world, one trial in Canada promises to be unique. After decades of research, development, and high hopes, scientists at the University of Western Ontario are ready to test a new type of vaccine known as SAV001 that they hope will prevent HIV infections.

What makes this trial different, said lead researcher Chil-Yong Kang, Ph.D., is that this is the first preventive vaccine to use a “killed whole” HIV-1 virus to activate a person’s immune system. This version of the virus, however, would be genetically altered so it would not be able to cause HIV infection. For insurance, the virus is also inactivated by using chemicals and radiation.

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The Scientist Who Discovered Hepatitis C Says He's Now Discovered the Vaccine

The Scientist Who Discovered Hepatitis C Says He's Now Discovered the Vaccine | Virology News | Scoop.it
In a poetic turn of virology, the scientist who discovered hepatitis C in 1989 has now also discovered a vaccine that will hopefully treat and prevent the disease.

 

Just shows you: stick with a thing for 20+ years....

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JN | Abstract | Sendai Virus-based Liposomes Enable Targeted Cytosolic Delivery of Nanoparticles in Brain Tumor-Derived Cells

These findings are the first to utilize the Sendai virus to achieve cytosolic, targeted intracellular binding of Qdots within Human brain tumor cells. The results are significant to the continued applicability of nanoparticles used for the molecular labeling of cancer cells to determine tumor heterogeneity, grade, and chemotherapeutic resistivity.

 

It is to like: using liposomes fused to inactivated Sendai to deliver Qdots.  Vironanotech rules!

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Monkey vaccine hints at how to stop HIV : Nature News & Comment

Monkey vaccine hints at how to stop HIV : Nature News & Comment | Virology News | Scoop.it

A vaccine made of an adenovirus prime and a modified-pox-virus boost was best at stopping infection. Three-quarters of the monkeys that received no vaccine developed SIV after one exposure, whereas only 12% of the animals that got the best vaccine did so.

 

Prime-boost studies and a good infection model...nice virology and vaccinology.  And a possible route to a human HIV vaccine

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The Tower : Contagious Virus Affects GW Students

"The norovirus has affected about 85 students this week, according to the GW University Student Health Service. Although experts are still unsure of where the virus originated, most of the cases have been found at the Foggy Bottom campus."

 

To be renamed the Soggy Bottom campus??  Sorry, couldn't resist...B-)

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H5N1 Pandemic Information News: A/H5N1 virus mutates against vaccines

I'm assuming this is in Vietnam, seeing as details are a little sketchy, but this could be getting serious.

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HIV downgrade set to change face of disease  - News |nation.co.ke

A major milestone in the history of HIV is underway and may forever change the face of the disease.

 

Interesting...suddenly AIDS becomes just another African chronic disease.  Because of course, everyone has access to ARVs.  Yeah, right.

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Transgenic Research, Volume 15, Number 4 - SpringerLink

Transgenic Research, Volume 15, Number 4 - SpringerLink | Virology News | Scoop.it

Here, we report the expression of the fusion (F) gene of the Newcastle disease virus (NDV) in transgenic maize plants. The expression of the transgene, driven by the maize ubiquitin promoter, caused accumulation of the F protein in maize kernels. The presence of the transgene was verified by Southern and western blots. Feeding chickens with kernels containing the F protein induced the production of antibodies, which conferred protection against a viral challenge. This protection was comparable to that conferred by a commercial vaccine. Possible uses of this plant-based F protein as a potential mucosal vaccine are discussed.

 

Going green: some day, all vaccines that matter will be made this way...B-)

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A single protein helps the body keep watch over the Epstein-Barr virus | e! Science News

Some 90 percent of people are exposed to the Epstein Barr virus (EBV) at some point in their life. Even though it is quickly cleared from the body, the virus can linger silently for years in small numbers of infected B cells.
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UPDATE 2-Deadly bird flu studies to stay secret for now - WHO

(Adds source close to U.S.biosecurity board, WHO quotes)By Stephanie Nebehay and Kate KellandGENEVA/LONDON, Feb 17 (Reuters) - Two studies showinghow scientists mutated the H5N1 bird flu virus into...

 

My take on this: "Asked about the potential bioterrorism risks of his and the U.S. team's work, Fouchier said "it was the view of the entire group" at the meeting that the risks that this particular virus or flu viruses in general could be used as bioterrorism agents "would be very, very slim".

"The risks are not nil, but they are very, very small," he said."

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CDC Warns Untreatable Gonorrhea Is on the Way

CDC Warns Untreatable Gonorrhea Is on the Way | Virology News | Scoop.it

'Gonorrhea, one of the most common sexually transmitted diseases in the United States, is increasingly showing resistance to one of the last known effective antibiotic treatments, leading researchers from the Centers for Disease Control to 'sound the alarm" about potentially untreatable forms of the disease.'

 

OK, so it's not a virus, but everyone should be scared of this: coming soon to a sexually promiscuous person near you....

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Experts delay H5N1 study decision

Experts delay H5N1 study decision | Virology News | Scoop.it
Experts have delayed a decision about whether controversial research into the H5N1 bird flu virus should be published.

 

And do it grinds on...meanwhile, so does the virus

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Virology Journal | Abstract | Rabies molecular virology, diagnosis, prevention and treatment

Virology Journal | Abstract | Rabies molecular virology, diagnosis, prevention and treatment | Virology News | Scoop.it
Rabies is an avertable viral disease caused by the rabid animal to the warm blooded animals (zoonotic) especially human. Rabies occurs in more than 150 countries and territories.

 

A very useful review on something that is an underestimated problem in developing countries.

Image courtesy of Russell Kightley Media (http://www.rkm.com.au)


Via Chris Upton + helpers
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Virology Journal | Rapid detection of sacbrood virus (SBV) by one-step reverse transcription loop-mediated isothermal amplification assay

Sacbrood virus (SBV) primarily infects honeybee broods, and in order to deal with the problem cost effective detection methods are required.

 

...and LAMP (http://en.wikipedia.org/wiki/Loop-mediated_isothermal_amplification) turns out to be a good way to do it!  Like this...

http://nar.oxfordjournals.org/content/28/12/e63/F1.large.jpg

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Hepatitis C-related deaths outpace HIV deaths, study says | From …

Hepatitis C-related deaths outpace HIV deaths, study says | From … | Virology News | Scoop.it
Hepatitis C-related deaths outpace HIV deaths, study says | From … http://t.co/iP0ktxnz...

 

...but not in Africa or Asia, I'd be willing to bet.

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Complete sequence of a cryptic virus from hemp (Cannabis sativa)

Complete sequence of a cryptic virus from hemp (Cannabis sativa) | Virology News | Scoop.it

ARCHIVES OF VIROLOGY
Volume 157, Number 2, 383-385

 

Hemp (Cannabis sativa) was found to be a useful propagation host for hop latent virus, a carlavirus. However, when virus preparations were analysed by electron microscopy, along with the expected filamentous particles, spherical particles with a diameter of around 34 nm were found. RNA from virus preparations was purified, and cDNA was prepared and cloned. Sequence information was used to search databases, and the greatest similarity was found with Primula malacoides virus 1, a putative new member of the genus Partitivirus. The full sequences of RNA 1 and RNA 2 of this new hemp cryptic virus were obtained.

 

Hey, man...this weed's like, cryptic, man...B-)

Can we now expect Cannabis mosaic, Cannabis leaf curl, Cannabis mild mottle and Cannabis reality distortion viruses?

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With Final Review of Phase IIb Viral Load Data Completed, Researchers Confirm Statistically Significant Reduction of … | StemCell Therapy MD

OSLO, NORWAY--(Marketwire -02/15/12)- Bionor Pharma (Oslo: BIONOR.OL - News) News Summary Final review of phase IIb data confirms statistically significant 64% reduction of viral load set point (average of the last two viral load measurements...

 

And here come more therapeutic vaccine interventions for AIDS patients: the gates are opening....

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Stuxnet Virus Infected 16000 Computers, Iran Says

Stuxnet Virus Infected 16000 Computers, Iran Says | Virology News | Scoop.it
TEHRAN, Iran (AP) — A senior Iranian intelligence official says an estimated 16000 computers were infected by the Stuxnet virus. The powerful virus targeted Iran's nuclear facilities and other industrial sites in 2010, and ...

 

ViroBlogy readers will know I think computer viruses are quite legitimate life forms - and should we be more worried about this, which is a genuinely engineered infectious agent, than H5N1?

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Egypt - Report of H9 influenza in poultry in 9 provinces - more than 50% mortality rate - FluTrackers

Egypt - Report of H9 influenza in poultry in 9 provinces - more than 50% mortality rate Egypt...

 

Interesting - as much for the machine translation as for anything else, which renders the content pretty much inscrutable.  But bottom line: H9N2 in Egypt and causing a problem in poultry.  Like the Twitter revolution, this may spread and spread....

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CIDRAP >> NSABB: Studies show how H5N1 can jump natural barrier

Interesting account of the papers that are ATTEMPTING to describe how researchers made H5N1 viruses that were aerosol transmitted in ferrets

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WHO calls for publication of the full details of the new avian flu virus

WHO calls for publication of the full details of the new avian flu virus | Virology News | Scoop.it
Science and Nature have papers that describe a version of the avian flu that spreads among mammals. The World Health Organization has now weighed in with its thoughts on whether they should be published.

 

One comment:

"The publication of the full details of the paper would allow anyone with a reasonable level of molecular biology skill to order up the requisite DNA and produce a copy of the newly evolved virus. That raises the risk that the virus could be spread by a lab that doesn't have the requisite containment expertise, or by someone who intentionally uses it as a weapon."

 

Utter bullshit!  The lab would have to ALSO have the skills in reverse genetics to be able to engineer ss(-)RNA segment expession in a context that would allow reassortment with a live flu virus, in order to make something at all!!

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Schmallenberg – Farmers Weekly

Schmallenberg – Farmers Weekly | Virology News | Scoop.it
News, video, background information and discussion on the spread of the Schmallenberg virus in the UK...

 

Sometimes you need to get news about viruses that is relevant to people whose living is affected...farmers, in this case

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What happened to bird flu? Deaths continue, new strain outsmarts poultry vaccine in Vietnam

What happened to bird flu? Deaths continue, new strain outsmarts poultry vaccine in Vietnam | Virology News | Scoop.it
HANOI, Vietnam — Thought bird flu was gone? Recent human deaths in Asia and Egypt are a reminder that the H5N1 virus is still alive and dangerous, and Vietnam is grappling with a new strain that has outsmarted vaccines used to protect poultry flocks.

 

And they sit in Geneva and argue....

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Slideshow: Common Cold, Flu, or Swine Flu Virus? See symptoms and treatments.

WebMD shows you cold symptoms and signs of flu virus. Learn what fever, cough, runny nose, and sore throat may mean, and treatment and prevention options.

 

I have a morbid fascination with this just now, having had sinusitis, rhinitis, headache AND fever.  Damn viruses....

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