SynBioFromLeukipposInstitute
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Synthetic biology may lead to the creation of smart microbes that can detect and treat disease 
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Genetically engineered microorganisms could replace flowers as sources of ingredients for perfumes – and even recreate scents from plants long extinct Via Integrated DNA Technologies
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It's never been easier to build your own biological creations.
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Does our DNA hold the key to creating one of the most long lasting and efficient storage devices around? Scientists certainly seem to think so.
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Seminar announcement
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How do bacteria sense their environment? How can we describe the genetic mechanisms behind this process? How can we use this knowledge to develop useful appl...
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Gerd Moe-Behrens's insight:
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Gerd Moe-Behrens's insight:
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Gerd Moe-Behrens's insight:
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From
gekoo
Synthetic Aesthetics: Investigating Synthetic Biology's Designs on Nature, Endy, in gekoo.co - Search, Find, Compare and Buy it Now - Deals and Offers Online - Discounts and Promotions
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MIT 7.91J Foundations of Computational and Systems Biology, Spring 2014 View the complete course: http://ocw.mit.edu/7-91JS14 Instructor: Ron Weiss This gues...
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Legendary biologist Edward O. Wilson explores three realms of ultimate biology from which we should expect major breakthroughs over the next several decades....
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Bioengineers at The University of Texas at Dallas have created a novel gene-delivery system that shuttles a gene into a cell, but only for a temporary stay, providing a potential new gene-therapy strategy for treating disease.
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From
phys
Deep in the heart of synthetic biology are the proteins that make it tick. Protein engineering is the crucial pulse of the booming, relatively new scientific discipline.
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Via Integrated DNA Technologies
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Gerd Moe-Behrens's insight:
*Programmable materials and the nature of the DNA bond* Nucleic acids are ubiquitous in biology because of their ability to encode vast amounts of information via canonical Watson-Crick base-pairing interactions. With the advent of chemical methods to make synthetic oligonucleotides of an arbitrary sequence, researchers can program entire libraries of molecules with orthogonal interactions, directed to assemble in highly specific arrangements. Early attempts to use DNA to make nanostructures led to topologically defined architectures, but ones that were too conformationally flexible to be used to guide the construction of well-defined nanoscale materials from the bottom up. In this Review, we discuss the key discoveries that have overcome this limitation and distill common design principles that have since led to a revolution in materials sophistication based on DNA-directed assembly. ADVANCES The experimental realization of DNA-based constructs that are sufficiently rigid so as to impart directionality to hybridization interactions marks a major milestone in the development of programmable materials assembly. This feat was accomplished simultaneously by the Mirkin Group and Seeman Group in 1996, but through chemically and conceptually distinct pathways. In one approach, rigidity is derived from multiple strand crossover events and the hybridization that stabilizes them to create a conformationally restricted DNA tile. In the other approach, a rigid non-nucleic acid–based nanoparticle (inorganic or organic) core acts as a template to organize functionalized DNA strands in a surface-normal orientation. It is appealing to draw the analogy between DNA-based constructs of this sort with the concepts of “bonds” and “valency” found in atomic systems. Just as understanding the nature of atomic bonding is crucial for chemists to manipulate the formation of molecular and supramolecular species, so too is an understanding of the nature of these DNA bonding modes necessary for nanoscientists to build complex and functional architectures to address materials needs. OUTLOOK The interest in nanoscale materials constructed by using DNA bonds has continued to grow steadily, but has seen a noteworthy explosion in relevance over the past several years. This is due in large part to the development of methods to move beyond simple clusters and crystals to more sophisticated nanostructured materials that are dynamic and stimuli responsive, are macroscopic in spatial extent, and exhibit emergent physical properties that arise from specific arrangements of matter. These techniques offer perhaps the most versatile way of organizing optically active materials into architectures that exhibit unusual and deliberately tailorable plasmonic and photonic properties. In addition, prospects include the use of these materials in biological settings, being that they are constructed, in large measure, from nucleic acid precursors. The ability to manipulate gene expression, deliver molecular payloads via DNA-based binding events, and detect relevant markers of disease with nanoscale spatial resolution represent some of the most fruitful avenues of future research."
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A bacterium has been used to wish people a Merry Xmas. Grown by Dr Munehiro Asally, an Assistant Professor at the University of Warwick, the letters used to spell MERRY XMAS are made of Bacillus subtilis, a non-pathogenic bacterium which is found in soil and also human gut.
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synthetic biology: inventing intelligent design http://t.co/Saiw6ZL4WR
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A Yale University lab has crafted the first synthetic molecules that have both the targeting and response functions of antibodies.
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Scott Kirsner
"Jason Kelly was in Manhattan Thursday to meet with a prospective customer in the perfume business. Kelly, a founder of Boston-based Ginkgo Bioworks , sells custom-crafted organisms — mostly yeast, bacteria, and algae — and one of the jobs they can do is make synthetic scents that might one day go into a fragrance that you spray or dab on.
http://bit.ly/1N1dNhm