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Scooped by
Dr. Alex Jimenez
October 23, 2019 4:26 PM
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Is your attention span decreasing? How often do you walk into rooms and forget why? How often do you feel you are not getting enough sleep or rest? If you answered yes to any of the previous questions, you may be experiencing brain fog. Brain fog is a symptom rather than a single condition and it can actually be caused by a very common factor: too much screen time. Many people today spend a significant amount of time staring at a screen than ever before. According to the American Optometric Association (AOA), an average office worker in the United States spends a minimum of seven hours a day sitting in front of a computer screen. While other recent research studies have shown that an average American adult spends as much as 11 hours a day looking at some type of screen of some kind, including mobile devices like smartphones. In light of this “digital revolution”, however, more and more healthy people in their 20’s, 30’s, and even in their 40’s have started experiencing brain fog, short-term memory loss, and insomnia as well as vision problems, headaches, and migraines. Although there isn’t an abundance of evidence, several research studies have begun to demonstrate the effects of too much screen time on our overall health and wellness. We will discuss why screen time causes brain fog, among other health issues.
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Scooped by
Dr. Alex Jimenez
October 22, 2019 4:23 PM
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Are you constantly feeling exhausted? Have you been noticing any mood changes? Do you struggle to focus on regular tasks? Brain fog, which often includes depression and fatigue, is a health issue that can have consequences on all facets of your life. Why Depression Causes Fatigue Depression is just one of the most frequent mental health issues in the United States. Some symptoms, which may stem from depression, are excessive feelings of guilt, hopelessness, insomnia, and fatigue as well as brain fog, among others. Depression, brain fog, and fatigue, or chronic tiredness, can frequently go hand in hand. It is a vicious cycle: brain fog makes you spend energy for you to make it through the day, which in turn, makes you feel even more tired when you also have depression. Then when you’re feeling unproductive, it worsens your depression even more and it can affect your sleep. The direction of causality has not been ascertained but researchers have found definite links between inflammation, brain fog, and depression. These links can go beyond just the cognitive and psychological aspects of depression and brain fog. Other health issues that can involve autoimmune and/or inflammatory processes also correlate with brain fog, including chronic fatigue syndrome, fibromyalgia, or rheumatoid arthritis. Therefore, several healthcare professionals and researchers now believe that inflammation may be a significant origin of depressive symptoms, although not the sole one.
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Scooped by
Dr. Alex Jimenez
October 18, 2019 3:32 PM
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How often do you become fatigued when driving compared to in the past? Or how often do you become fatigued when reading compared to in the past? And, how often do you feel you are not getting enough sleep or rest? If you experience any of these problems often, you may be experiencing brain inflammation and fatigue due to a variety of health issues. Chronic fatigue syndrome (CFS) and other similar health issues, such as Gulf War illness (GWI), share many common symptoms, several of which can include muscle pain and discomfort, fatigue, cognitive impairment, disrupted sleep, sore throat, headaches, and general malaise, typically after participating in any type of physical activity or exercise.
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Scooped by
Dr. Alex Jimenez
October 16, 2019 4:42 PM
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According to the World Health Organization, depression is one of the main causes of disability worldwide. Moreover, approximately 30 percent to 60 percent of patients don’t respond to the currently available antidepressant treatments. That means that about 40 percent to 70 percent of patients aren’t being helped by existing antidepressant treatments. One region of research studies can ultimately shed some light on why many patients are not helped by antidepressants.
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Scooped by
Dr. Alex Jimenez
October 11, 2019 5:34 PM
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Of all of the wide array of health issues that healthcare professionals talk to their patients about, there is one which is tremendously overlooked and not taken seriously: brain fog. Many people suffer from brain fog and fatigue and unfortunately, many people are left to fend for themselves when it comes to this health issue. Patients describe feeling as if they’re living in a haze, their lives passing them by. Instead of being engaged in the present moment, patients describe feeling as though they’re seeing life from a distance. Their thinking is no longer sharp, and their brilliant minds are sidelined. Why do health issues like these fall through the cracks of conventional medicine? This may be because there’s currently no definitive treatment available for brain fog. The purpose of the following article is to discuss the causes of inflammation and brain fog. Understanding the reasons for this type of health issue may hopefully help shine a new light on future treatments. Brain Fog and Inflammation Inflammation is an essential part of the immune system. We need inflammation to protects us from injury, infection, and illness. However, as with everything else in the human body, it is all about balance. An excessive amount of inflammation can cause the blood-brain barrier (BBB) to become more permeable, leading to brain inflammation. Neuroinflammation is sometimes known as “leaky brain syndrome” and this inflammatory oxidative stress (OS) in the hypothalamus of the brain is ultimately believed to be the root cause of brain fog, among other neurological diseases, such as Alzheimer’s disease.
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Scooped by
Dr. Alex Jimenez
October 10, 2019 4:35 PM
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Inflammatory reactions in the central nervous system (CNS) are currently known to be associated with many neurological disorders. In neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), there is considerable penetration of different leukocyte subsets into the CNS or there is severe activation of microglial cells which increases many inflammatory mediators in the CNS. In acute CNS disorders, including delayed corrosion associated with vasospasm after subarachnoid hemorrhage (SAH), ischemic stroke, spontaneous intracerebral hemorrhage (ICH), and traumatic brain injury (TBI), current evidence from a variety of research studies reveal that inflammation may be a possible target for treatment. Inflammation is becoming a promising region of research study for new treatments. To speed up the process of translating this information to clinical applications, a number of significant problems have to be addressed as their capacity to continuously identify characteristic cerebral deficits in people with neurodegenerative diseases, the connections of brain injuries to clinical symptoms and genetic diagnosis as well as the level to which the harm respond to various treatment approaches. In this article, findings that address some of these problems are reported by several researchers.
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Scooped by
Dr. Alex Jimenez
October 8, 2019 4:19 PM
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MSG is a food additive which is found in the majority of the industrial foods. It boosts the taste of the food hence attracting customers. There is no value in terms of nutrition and it really does nothing to the eater, however, it can have many effects on foods. MSG is known as an “excitotoxin” or neurotoxin. Research studies have found that it has devastating and degenerative effects on the brain and the nervous system. The neurons or brain cells overstimulate and fatigue to their death. MSG enters the brain through the membranes in the mouth and the throat. It also enters the blood-stream through the digestion of food in the gastrointestinal (GI) tract. MSG “tricks” the human body into believing that it is getting value from these foods. MSG is not a natural substance found in nature. It’s a man-made chemical from glutamic acid, an amino acid found in proteins. Amino acids do happen naturally in animal cells and in several plant cells. The kinds of amino acids have been processed through the change of this pure form of glutamate. Some of the materials used for this purpose include starches, molasses, and corn. The manipulation procedure generates this type of glutamate. The d-glutamate is not found naturally. The free glutamates can enter the body about eight to ten times faster compared to natural glutamates. Natural glutamate is found in foods such as tomatoes, mushrooms, and milk. Techniques used to manufacture glutamate were not in use before the 1960s. The MSG in use now is not natural. In the article, we will discuss how MSG is associated with neurological diseases.
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Scooped by
Dr. Alex Jimenez
October 3, 2019 9:55 PM
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Many patients with peripheral neuropathy often believe that their painful symptoms are irreversible or permanent. However, Dr. John Coppola and Dr. Valerie Monteiro describe that peripheral neuropathy can be treated by treating the underlying source of the painful symptoms. Several patients discuss their painful peripheral neuropathy symptoms and how these affected their overall quality of life. Moreover, the patients also discuss how Dr. John Coppola and Dr. Valerie Monteiro helped treat their painful peripheral neuropathy symptoms through the use of a variety of treatment methods and techniques. Dr. Alex Jimenez, doctor of chiropractic in El Paso, TX, can help treat painful symptoms associated with peripheral neuropathy. Dr. Alex Jimenez is the non-surgical choice for chiropractic care and peripheral neuropathy treatment. Neuropathy is a medical term used to describe a collection of general diseases or malfunctions which affect the nerves. The causes of neuropathy, or nerve damage, can vary among individuals and these may be caused by different: - Diseases
- Injuries
- Infections
- Vitamin deficiencies
Neuropathy can also be classified according to the location of the nerves being affected and according to the disease-causing it. Neuropathy caused by diabetes is called diabetic neuropathy. Furthermore, depending on which nerves are affected will depend on the symptoms that will manifest. Peripheral neuropathy is simply referred to as neuropathy, which is a state that happens when the nerves become damaged or injured, oftentimes simply disturbed. It’s estimated that neuropathy affects roughly 2.4 percent of the general populace and approximately 8 percent of people older than age 55. Type Neuropathy can affect any of the three types of peripheral nerves: - Sensory nerves transmit messages from sensory organs:
- Eyes
- Nose
- Brain
- Motor nerves track the movement of the muscles
- Autonomic nerves regulate the involuntary body functions
Sometimes, neuropathy will only impact one nerve. This is medically referred to as mononeuropathy and instances of it include: - Ulnar neuropathy affects the elbow
- Radial neuropathy affects the arms
- Peroneal neuropathy affects the knees
- Femoral neuropathy affects the thighs
- Cervical neuropathy affects the neck
Sometimes, two or more isolated nerves in separate regions of the body can become damaged, injured or disrupted, resulting in mono neuritis multiplex neuropathy. Most of the time, multiple peripheral nerves malfunction at the same time, a condition called polyneuropathy. Cause Neuropathies are often inherited from birth or they develop later in life. The most frequent inherited neuropathy is the Charcot-Marie-Tooth disease, which affects 1 in 2,500 people in the USA. Although healthcare professionals are sometimes not able to pinpoint the exact reason for an acquired neuropathy, medically referred to as idiopathic neuropathy. There are many known causes for them, including: - Systemic diseases - a systemic disease is one that affects the whole body.
- Physical trauma
- Infectious diseases
- Autoimmune disorders
The most frequent systemic cause behind peripheral neuropathy is diabetes, which can lead to chronically high blood glucose levels that harm nerves. Other systemic issues can cause neuropathy, including: - Kidney disorders permit high levels of nerve-damaging toxic chemicals to flow in the blood
- Toxins from exposure to heavy metals include:
- Arsenic
- Lead
- Mercury
- Thallium
- Drugs/medications, including anti-cancer medications, anticonvulsants, antivirals, and antibiotics
- Chemical imbalances because of liver illnesses.
- Hormonal diseases, like hyperthyroidism, which disturbs metabolic processes, and potentially induces cells and body parts to exert pressure on the nerves.
- Deficiencies in vitamins, such as E, B1 (thiamine), B6 (pyridoxine), B12, and niacin can be vital for healthy nerves.
- Alcohol abuse induces vitamin deficiencies and could harm nerves.
- Cancers and tumors can exert damaging pressure on nerve fibers and paths.
- Chronic inflammation can damage protective tissues around nerves, which makes them more vulnerable to compression, getting inflamed and swollen.
- Blood diseases and blood vessel damage, which may damage or injure nerve tissue by decreasing the available oxygen supply
Symptoms Depending on the reason and unique to each patient, signs, and symptoms of neuropathy can include: - Pain
- Tingling
- Burning/prickling sensations
- Increased sensitivity to touch
- Muscle weakness
- Temporary or permanent numbness;
- Paralysis
- Dysfunction in glands or organs
- Impairment in urination and
- Sexual function
Symptoms are dependent on autonomic, sensory, or motor nerves or a combination are affected. Autonomic nerve damage can start a chain reaction of physiological functions like blood pressure or create gastrointestinal problems and issues. Damage or dysfunction in the sensory nerves may impact sensations and sense of equilibrium or balance, while injury to motor nerves affects movement and reflexes. When both sensory and motor nerves are involved, the condition is known as sensorimotor polyneuropathy. Complications Peripheral neuropathy may result in several complications, as a result of disease or its symptoms. Numbness from the ailment can allow you to be less vulnerable to temperatures and pain, making you more likely to suffer from burns and serious wounds. The lack of sensations in the feet, for instance, can make you more prone to developing infections from minor traumatic accidents, particularly for diabetics, who heal more slowly than other people, including foot ulcers and gangrene. Furthermore, muscle atrophy may cause you to develop particular physical disfigurements, such as pes cavus, a condition marked by an abnormally high foot arch, and claw-like deformities in the feet and palms. Treatment The first step in neuropathy treatment should be finding the root cause that's causing the neuropathy. Treatment of diseases such as: - Diabetes
- Guillain-Barre syndrome
- Rheumatoid arthritis
- Sarcoidosis
- Other underlying diseases
Prevents continued nerve damage and in cases heals the damaged nerves. If you are unaware of any underlying disease that is causing the peripheral neuropathy, make sure to let your doctor know of abnormal symptoms. Medication Peripheral neuropathy can be treated with various medications. The first type used to treat mild symptoms are: - Over-the-counter pain medications
In more severe cases: - Opiates
- Narcotic medications
- Anti-seizure medications
A doctor may prescribe a lidocaine patch or anti-depressants to relieve symptoms. Patients should thoroughly discuss neuropathy medication with a doctor before proceeding. Chiropractic/Massage/Physical Therapy Various manual therapies can benefit symptoms in neuropathy treatment. A therapist or chiropractor will perform various manipulation techniques, and teach exercises and stretches to help improve symptoms combined with increased muscle strength/control. A therapist may also recommend braces or splints to improve mobility. Patients should attend all physical therapy sessions to gain maximum benefits. Acids Supplements like: - Essential acids called ALA (alpha-Lipoic acid)
- GLA (gamma-linolenic acid) and omega-3 fatty acids
These can have a beneficial effect on diabetic peripheral neuropathy. L-Carnitine L-carnitine is a substance that the body makes and stores in the: There have been reports that certain diabetics with neuropathy symptoms could regain regular sensation in the limbs when they increased their consumption of carnitine called acetyl-L-carnitine. - Red meat
- Peanut butter
- Dairy products
Are good dietary sources of this nutrient. Supplements are also available at health food stores and pharmacies and health/wellness clinics. Vitamin Supplements Vitamin deficiencies can result in peripheral neuropathy in some people. Therefore there needs to be a replenishing of vitamins: These can help to decrease symptoms. Recommended dosages are 300mg daily of vitamin E. Doses of the different B vitamins differ, but one option for patients is to take a daily B-complex supplement. Herb Supplements Herbal remedies are an alternative to explore. St. John's Wort, is a herbal supplement that can be taken orally and can reduce the pain. Topical creams that have capsaicin, which is an anti-inflammatory found in chili peppers, can reduce the burning sensation. Acupuncture Acupuncture can be an effective way to manage peripheral neuropathy. Acupuncture uses pressure points throughout the body to realign the body's energy, called the qi or chi. Also, movement therapy is a way to manage the condition. Tai chi and yoga can help: - Align the body
- Mind
- Encourage relaxation
- Distract from the pain
El Paso’s Premier Wellness & Injury Care Clinic. Our services are specialized and focused on injuries and the complete recovery process. Our areas of practice include: As El Paso’s Chiropractic Rehabilitation Clinic & Integrated Medicine Center, we passionately are focused on treating patients after frustrating injuries and chronic pain syndromes. We focus on improving your ability through flexibility, mobility and agility programs custom-tailored for all age groups and disabilities. We want you to live a life filled with more energy, a positive attitude, better sleep, less pain, proper body weight and educated on how to maintain this way of life. We're Ready To Help Get You Healthy! Health Grades: http://www.healthgrades.com/review/3SDJ4 Facebook Clinical Page: https://www.facebook.com/dralexjimene... Facebook Sports Page: https://www.facebook.com/pushasrx/ Facebook Injuries Page: https://www.facebook.com/elpasochirop... Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeurop... Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ Clinical Testimonies: https://www.dralexjimenez.com/categor...
Information: Dr. Alex Jimenez – Chiropractor
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com Sports Injury Site: https://chiropracticscientist.com Back Injury Site: https://www.elpasobackclinic.com Pinterest: https://www.pinterest.com/dralexjimenez/ Twitter: https://twitter.com/dralexjimenez Twitter: https://twitter.com/crossfitdoctor
Recommend: PUSH-as-Rx ®™
Rehabilitation Center: https://www.pushasrx.com
Facebook: https://www.facebook.com/PUSHftinessa... PUSH-as-Rx: http://www.push4fitness.com/team/
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Scooped by
Dr. Alex Jimenez
October 2, 2019 6:42 PM
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When compared to other central nervous system (CNS) health issues, chronic neurodegenerative diseases can be far more complicated. Foremostly, because the compromised mitochondrial function has been demonstrated in many neurodegenerative diseases, the resulting problems in energy sources are not as severe as the energy collapse in ischemic stroke. Therefore, if excitotoxicity contributes to neurodegeneration, a different time of chronic excitotoxicity needs to be assumed. In the following article, we will outline what is known about the pathways that may cause excitotoxicity in neurodegenerative diseases. We will specifically discuss that in amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD) and Huntington’s disease (HD) as fundamental examples with sufficiently validated animal models in research studies.
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Scooped by
Dr. Alex Jimenez
September 27, 2019 7:38 PM
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Previous research studies suggest that L-aspartate, like L-glutamate, triggers excitatory activity on neurons. L-aspartate functions with L-glutamate in the synaptic vesicles of asymmetric excitatory synapses. But, the total concentration of these in the human brain (0.96-1.62 μmol/gram wet weight), their extracellular concentrations in the cortex as measured by microdialysis (1.62 μM for L-aspartate and 9.06 μM for L-glutamate) and their supply according to immunohistochemistry suggest that L-aspartate is significantly less abundant than L-glutamate. Moreover, L-aspartate is a powerful agonist for NMDA receptors but not for other iGluRs with an EC50 just eight-fold higher than that of L-glutamate. EAATs which play a fundamental role in the uptake of all vesicular released L-glutamate in the central nervous system (CNS) also requires the utilization of L-aspartate. L-aspartate is perhaps as less essential as L-glutamate connected to the total excitatory activity associated with iGluRs. Along with its role as a neurotransmitter, as previously mentioned, L-aspartate is also necessary as a substrate for aspartate amino-transferase which turns into 2-oxoglutarate and L-glutamate to transport to the cortical vesicles of glutamatergic neurons which may also consequently and indirectly increase L-glutamate release.
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Scooped by
Dr. Alex Jimenez
September 26, 2019 3:20 PM
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L-glutamate is one of the main excitatory neurotransmitters in the human brain and it plays an essential role in practically all activities of the nervous system. In the following article, we will discuss the general principles of L-glutamate signaling in the brain. Then, we will demonstrate this scheme by describing the different pools of extracellular glutamate, including the synaptic, the perisynaptic, and the extrasynaptic, resulting from vesicular and non-vesicular sources or abnormally located glutamate receptors outside of synapses as well as discuss their possible physiological functions in the human brain.
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Scooped by
Dr. Alex Jimenez
September 24, 2019 2:43 PM
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Excitotoxicity is a pathological mechanism seen in a variety of health issues where an excessive synaptic excitation causes neuronal death and is also believed to be caused by the extracellular accumulation of the excitatory neurotransmitter glutamate, which triggers and connects ionotropic N-methyl-D-aspartate glutamatergic receptors (NMDARs) in the brain. Generally, NMDARs regulate and maintain calcium in cells to help manage physiological mechanisms like synaptic plasticity and memory, however, excessive stimulation can ultimately increase intracellular calcium which triggers cell death signaling to activate apoptosis. This pathological mechanism has been suggested in a variety of health issues, such as traumatic brain injury (TBI) and Alzheimer’s disease (AD), where it is extensively examined to understand health issues and treatment approaches. In a stroke, excitotoxicity has been shown to be the main pathological mechanism where neuronal damage happens and it is considered to be a well-known goal for many recent attempts at developing stroke therapeutics. Stroke is an acute brain health issue which causes neuronal damage which has currently no safe and effective neuroprotective treatment approaches. Immediately following a stroke, the brain tissue loses blood perfusion and the center of the infarct deteriorates quickly. This then causes milder ischemia and many brain cells or neurons will result in delayed death which can take up to several hours or even days. Research studies show that the mechanism of cell death is mainly NMDA receptor-dependent excitotoxicity. In ischemic areas, extracellular glutamate levels increase while preventing glutamate release, synaptic activity, or NMDAR activation which was capable of limiting cell death in a variety of stroke models. Thus, preventing excitotoxicity is an important treatment approach for reducing brain damage and improving patient outcome measures following a stroke, and this has definitely encouraged extensive efforts towards developing NMDA receptor-based stroke treatment approaches over the last two decades. Unfortunately, these have largely met with rather disappointing results. Several research studies have failed to find the expected efficiency of NMDAR for decreasing brain injuries. The reasons behind the basic research study results and clinical trials are still unknown, however, several reasons have been suggested. These include, but are not limited to, the inability to utilize the correct doses necessary for neuroprotection due to their side-effects, the inability to use the drugs within their neuroprotective windows, poor experimental designs, and heterogeneity in the patient population. However, as we will briefly summarize in the following article, improvement in our understanding of the physiological and pathological mechanisms of NMDAR activation as well as the different pathways connected to different NMDAR subtypes, has allowed researchers to develop new treatment approaches which improve therapeutic windows and increase specificity for death signaling pathways, achieving neuroprotection without interrupting other essential signaling pathways downstream of the NMDAR receptor.
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Scooped by
Dr. Alex Jimenez
September 22, 2019 2:12 PM
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An extreme case of picky eating caused a 17-year-old’s blindness, according to a case study from the University of Bristol. The patient, who had first visited his general practitioner complaining of tiredness, had a normal BMI and height and no visible signs of malnutrition.
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Scooped by
Dr. Alex Jimenez
October 22, 2019 5:00 PM
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Have you been experiencing noticeable variations in your mental speed? Do you suffer from pain, discomfort, and inflammation? Have you been experiencing fatigue, especially after meals or exposure to chemicals, scents, or pollutants? If you answered yes to any of the previous questions, you may be experiencing brain fog, unclear thoughts or concentration. Brain fog is a well-known symptom associated with a variety of health issues. It can affect many brain functions, including memory and concentration. It can occur as a result of poor lifestyle habits, including stress, an unhealthy diet, and lack of sleep, or due to other health issues, including multiple sclerosis and chronic fatigue syndrome. Moreover, brain fog can be accompanied by other symptoms like vision problems. In the following article, we will discuss brain fog and vision problems.
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Scooped by
Dr. Alex Jimenez
October 18, 2019 10:00 PM
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Dr. John Coppola and Dr. Valerie Monteiro know the symptoms associated with peripheral neuropathy. Since many health professionals clarify peripheral neuropathy as an irreversible and permanent health problem which can only be handled via the usage of drugs/medications, Dr. Coppola and Dr. Monteiro help cure cervical disease symptoms by treating the origin of the health dilemma. Low-level laser therapy (LLLT) is a non-invasive treatment approach that could help naturally raise oxygen, blood circulation and flow within the human body. LLLT can speed up recovery to be stimulated by the mitochondria referred to as the cell's powerhouses. Dr. Coppola and Dr. Monteiro clarify how low-level laser treatment can help treat cervical disease symptoms and help overall well-being. Dr. Alex Jimenez, a chiropractor in El Paso, TX, helps treat peripheral neuropathy symptoms and other wellness problems. LLT Laser Therapy for Peripheral Neuropathy El Paso, TX (2019) Neuropathy is a medical term used to describe a collection of general diseases or malfunctions which affect the nerves. The causes of neuropathy, or nerve damage, can vary among individuals and these may be caused by different: - Diseases
- Injuries
- Infections
- Vitamin deficiencies
Neuropathy can also be classified according to the location of the nerves being affected and according to the disease-causing it. Neuropathy caused by diabetes is called diabetic neuropathy. Furthermore, depending on which nerves are affected will depend on the symptoms that will manifest. Peripheral neuropathy is simply referred to as neuropathy, which is a state that happens when the nerves become damaged or injured, oftentimes simply disturbed. It’s estimated that neuropathy affects roughly 2.4 percent of the general populace and approximately 8 percent of people older than age 55. Type Neuropathy can affect any of the three types of peripheral nerves: - Sensory nerves transmit messages from sensory organs:
- Eyes
- Nose
- Brain
- Motor nerves track the movement of the muscles
- Autonomic nerves regulate the involuntary body functions
Sometimes, neuropathy will only impact one nerve. This is medically referred to as mononeuropathy and instances of it include: - Ulnar neuropathy affects elbow
- Radial neuropathy affects arms
- Peroneal neuropathy affects knees
- Femoral neuropathy affects thighs
- Cervical neuropathy affects neck
Sometimes, two or more isolated nerves in separate regions of the body can become damaged, injured or disrupted, resulting in mono neuritis multiplex neuropathy. Most of the time, multiple peripheral nerves malfunction at the same time, a condition called polyneuropathy. Cause Neuropathies are often inherited from birth or they develop later in life. The most frequent inherited neuropathy is the Charcot-Marie-Tooth disease, which affects 1 in 2,500 people in the USA. Although healthcare professionals are sometimes not able to pinpoint the exact reason for an acquired neuropathy, medically referred to as idiopathic neuropathy. There are many known causes for them, including: - Systemic diseases - a systemic disease is one that affects the whole body.
- Physical trauma
- Infectious diseases
- Autoimmune disorders
The most frequent systemic cause behind peripheral neuropathy is diabetes, which can lead to chronically high blood glucose levels that harm nerves. Other systemic issues can cause neuropathy, including: - Kidney disorders permit high levels of nerve-damaging toxic chemicals to flow in the blood
- Toxins from exposure to heavy metals include:
- Arsenic
- Lead
- Mercury
- Thallium
- Drugs/medications, including anti-cancer medications, anticonvulsants, antivirals, and antibiotics
- Chemical imbalances because of liver illnesses.
- Hormonal diseases, like hyperthyroidism, which disturbs metabolic processes, and potentially induces cells and body parts to exert pressure on the nerves.
- Deficiencies in vitamins, such as E, B1 (thiamine), B6 (pyridoxine), B12, and niacin can be vital for healthy nerves.
- Alcohol abuse induces vitamin deficiencies and could harm nerves.
- Cancers and tumors can exert damaging pressure on nerve fibers and paths.
- Chronic inflammation can damage protective tissues around nerves, which makes them more vulnerable to compression, getting inflamed and swollen.
- Blood diseases and blood vessel damage, which may damage or injure nerve tissue by decreasing the available oxygen supply
Symptoms Depending on the reason and unique to each patient, signs, and symptoms of neuropathy can include: - Pain
- Tingling
- Burning/prickling sensations
- Increased sensitivity to touch
- Muscle weakness
- Temporary or permanent numbness;
- Paralysis
- Dysfunction in glands or organs
- Impairment in urination and
- Sexual function
Symptoms are dependent on autonomic, sensory, or motor nerves or a combination are affected. Autonomic nerve damage can start a chain reaction of physiological functions like blood pressure or create gastrointestinal problems and issues. Damage or dysfunction in the sensory nerves may impact sensations and sense of equilibrium or balance, while injury to motor nerves affects movement and reflexes. When both sensory and motor nerves are involved, the condition is known as sensorimotor polyneuropathy. Complications Peripheral neuropathy may result in several complications, as a result of disease or its symptoms. Numbness from the ailment can allow you to be less vulnerable to temperatures and pain, making you more likely to suffer from burns and serious wounds. The lack of sensations in the feet, for instance, can make you more prone to developing infections from minor traumatic accidents, particularly for diabetics, who heal more slowly than other people, including foot ulcers and gangrene. Furthermore, muscle atrophy may cause you to develop particular physical disfigurements, such as pes cavus, a condition marked by an abnormally high foot arch, and claw-like deformities in the feet and palms. Treatment The first step in neuropathy treatment should be finding the root cause that's causing the neuropathy. Treatment of diseases such as: - Diabetes
- Guillain-Barre syndrome
- Rheumatoid arthritis
- Sarcoidosis
- Other underlying diseases
Prevents continued nerve damage and in cases heals the damaged nerves. If you are unaware of any underlying disease that is causing the peripheral neuropathy, make sure to let your doctor know of abnormal symptoms. Medication Peripheral neuropathy can be treated with various medications. The first type used to treat mild symptoms are: - Over-the-counter pain medications
In more severe cases: - Opiates
- Narcotic medications
- Anti-seizure medications
A doctor may prescribe a lidocaine patch or anti-depressants to relieve symptoms. Patients should thoroughly discuss neuropathy medication with a doctor before proceeding. Chiropractic/Massage/Physical Therapy Various manual therapies can benefit symptoms in neuropathy treatment. A therapist or chiropractor will perform various manipulation techniques, and teach exercises and stretches to help improve symptoms combined with increased muscle strength/control. A therapist may also recommend braces or splints to improve mobility. Patients should attend all physical therapy sessions to gain maximum benefits. Low-level-laser-therapy LLT The primary and most debilitating symptom of diabetic peripheral neuropathy is a sensation of tingling, prickling, buzzing, pinching, burning, and/or sharp jabbing stabbing pain in the feet. Low-Level Laser Therapy (LLT) takes information from the receptors on the membrane of the cell and mitochondrion or the engine of the cell. This information reaches the cell's DNA, that directly controls cell function. When cells receive better information, they work better, along with the tissues they make up like: - Bones
- Cartilage
- Tendons
- Ligaments
LLT promotes the healing and regeneration of damaged tissues, and its systemic effects on tissue function are also carried throughout the body by blood and meridians or energy channels. The key basic physiological effects of llt low-level laser light include: - Increased cell membrane polarization/permeability
- Adenosine-5-triphosphate (ATP) production and respiratory activity
- Enzyme activity
- Collagen and epithelial production
- Capillary formation
- Macrophage (immune system) activity
- Analgesic effects due to elevated endorphin production
- Electrolytic nerve blockage
- Improved blood and lymph flow
- An anti-inflammatory effect from improved circulation and accelerated tissue regeneration
- Increased production of antioxidants
An additional benefit is that the light energy from llt low-level lasers will only be absorbed by cells and tissues that are not functioning normally and do not go after healthy cells. Low-level laser therapy llt has the potential of providing an effective means of reducing low back pain that is: - Simple
- Quick
- Non-invasive
- Side-effect free
Vitamin Supplements Vitamin deficiencies can result in peripheral neuropathy in some people. Therefore there needs to be a replenishing of vitamins: These can help to decrease symptoms. Recommended dosages are 300mg daily of vitamin E. Doses of the different B vitamins differ, but one option for patients is to take a daily B-complex supplement. Herbal Supplements Herbal remedies are an alternative to explore. St. John's Wort, is a herbal supplement that can be taken orally and can reduce the pain. Topical creams that have capsaicin, which is an anti-inflammatory found in chili peppers, can reduce the burning sensation. El Paso’s Premier Wellness & Injury Care Clinic. Our services are specialized and focused on injuries and the complete recovery process. Our areas of practice include: As El Paso’s Chiropractic Rehabilitation Clinic & Integrated Medicine Center, we passionately are focused on treating patients after frustrating injuries and chronic pain syndromes. We focus on improving your ability through flexibility, mobility and agility programs custom-tailored for all age groups and disabilities. We want you to live a life filled with more energy, a positive attitude, better sleep, less pain, proper body weight and educated on how to maintain this way of life. We Are Ready To Get You Healthy & Back On Track! Health Grades: http://www.healthgrades.com/review/3SDJ4 Facebook Clinical Page: https://www.facebook.com/dralexjimene... Facebook Sports Page: https://www.facebook.com/pushasrx/ Facebook Injuries Page: https://www.facebook.com/elpasochirop... Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeurop... Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ Clinical Testimonies: https://www.dralexjimenez.com/categor...
Information: Dr. Alex Jimenez – Chiropractor
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com Sports Injury Site: https://chiropracticscientist.com Back Injury Site: https://www.elpasobackclinic.com Pinterest: https://www.pinterest.com/dralexjimenez/ Twitter: https://twitter.com/dralexjimenez Twitter: https://twitter.com/crossfitdoctor
Recommend: PUSH-as-Rx ®™
Rehabilitation Center: https://www.pushasrx.com
Facebook: https://www.facebook.com/PUSHftinessa... PUSH-as-Rx: http://www.push4fitness.com/team/
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Scooped by
Dr. Alex Jimenez
October 17, 2019 4:43 PM
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Is your memory noticeably declining? Are you having a hard time remembering names and phone numbers? Or is your ability to focus noticeably declining? If you’ve experienced any of these situations, you may ultimately be experiencing brain fog. What is Brain Fog? Brain fog is not a health issue but rather a symptom of other injuries or conditions. It is a cognitive dysfunction involving: - memory problems
- lack of mental clarity
- poor concentration
- inability to focus
Several people can also experience brain fog as mental fatigue. Based on the seriousness of brain fog, it may ultimately interfere with work, school, or any other regular tasks. However, it doesn’t have to be a permanent problem in your lifetime.
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Scooped by
Dr. Alex Jimenez
October 11, 2019 7:38 PM
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Dr. John Coppola and Dr. Valerie Monteiro understand the symptoms associated with peripheral neuropathy. While many healthcare professionals describe peripheral neuropathy as an irreversible and permanent health issue which can only be managed through the utilization of drugs/medications, Dr. John Coppola and Dr. Valerie Monteiro can help treat peripheral neuropathy symptoms by treating the source of the health issue. Low-level laser therapy (LLLT) is a non-invasive treatment approach that can help naturally increase oxygen, blood flow, and circulation in the human body. LLLT can also stimulate the mitochondria, often known as the powerhouses of the cell, to stimulate recovery in the human body. Dr. John Coppola and Dr. Valerie Monteiro explain how low-level laser therapy can help treat peripheral neuropathy symptoms and stimulate overall well-being. Dr. Alex Jimenez, a chiropractor in El Paso, TX, can help treat peripheral neuropathy symptoms as well as a variety of other health issues. Neuropathy is a medical term used to describe a collection of general diseases or malfunctions which affect the nerves. The causes of neuropathy, or nerve damage, can vary among individuals and these may be caused by different: - Diseases
- Injuries
- Infections
- Vitamin deficiencies
Neuropathy can also be classified according to the location of the nerves being affected and according to the disease-causing it. Neuropathy caused by diabetes is called diabetic neuropathy. Furthermore, depending on which nerves are affected will depend on the symptoms that will manifest. Peripheral neuropathy is simply referred to as neuropathy, which is a state that happens when the nerves become damaged or injured, oftentimes simply disturbed. It’s estimated that neuropathy affects roughly 2.4 percent of the general populace and approximately 8 percent of people older than age 55. Type Neuropathy can affect any of the three types of peripheral nerves: - Sensory nerves transmit messages from sensory organs:
- Eyes
- Nose
- Brain
- Motor nerves track the movement of the muscles
- Autonomic nerves regulate the involuntary body functions
Sometimes, neuropathy will only impact one nerve. This is medically referred to as mononeuropathy and instances of it include: - Ulnar neuropathy affects the elbow
- Radial neuropathy affects the arms
- Peroneal neuropathy affects the knees
- Femoral neuropathy affects the thighs
- Cervical neuropathy affects the neck
Sometimes, two or more isolated nerves in separate regions of the body can become damaged, injured or disrupted, resulting in mono neuritis multiplex neuropathy. Most of the time, multiple peripheral nerves malfunction at the same time, a condition called polyneuropathy. Cause Neuropathies are often inherited from birth or they develop later in life. The most frequent inherited neuropathy is the Charcot-Marie-Tooth disease, which affects 1 in 2,500 people in the USA. Although healthcare professionals are sometimes not able to pinpoint the exact reason for an acquired neuropathy, medically referred to as idiopathic neuropathy. There are many known causes for them, including: - Systemic diseases - a systemic disease is one that affects the whole body.
- Physical trauma
- Infectious diseases
- Autoimmune disorders
The most frequent systemic cause behind peripheral neuropathy is diabetes, which can lead to chronically high blood glucose levels that harm nerves. Other systemic issues can cause neuropathy, including: - Kidney disorders permit high levels of nerve-damaging toxic chemicals to flow in the blood
- Toxins from exposure to heavy metals include:
- Arsenic
- Lead
- Mercury
- Thallium
- Drugs/medications, including anti-cancer medications, anticonvulsants, antivirals, and antibiotics
- Chemical imbalances because of liver illnesses.
- Hormonal diseases, like hyperthyroidism, which disturbs metabolic processes, and potentially induces cells and body parts to exert pressure on the nerves.
- Deficiencies in vitamins, such as E, B1 (thiamine), B6 (pyridoxine), B12, and niacin can be vital for healthy nerves.
- Alcohol abuse induces vitamin deficiencies and could harm nerves.
- Cancers and tumors can exert damaging pressure on nerve fibers and paths.
- Chronic inflammation can damage protective tissues around nerves, which makes them more vulnerable to compression, getting inflamed and swollen.
- Blood diseases and blood vessel damage, which may damage or injure nerve tissue by decreasing the available oxygen supply
Symptoms Depending on the reason and unique to each patient, signs, and symptoms of neuropathy can include: - Pain
- Tingling
- Burning/prickling sensations
- Increased sensitivity to touch
- Muscle weakness
- Temporary or permanent numbness;
- Paralysis
- Dysfunction in glands or organs
- Impairment in urination and
- Sexual function
Symptoms are dependent on autonomic, sensory, or motor nerves or a combination are affected. Autonomic nerve damage can start a chain reaction of physiological functions like blood pressure or create gastrointestinal problems and issues. Damage or dysfunction in the sensory nerves may impact sensations and sense of equilibrium or balance, while injury to motor nerves affects movement and reflexes. When both sensory and motor nerves are involved, the condition is known as sensorimotor polyneuropathy. Complications Peripheral neuropathy may result in several complications, as a result of disease or its symptoms. Numbness from the ailment can allow you to be less vulnerable to temperatures and pain, making you more likely to suffer from burns and serious wounds. The lack of sensations in the feet, for instance, can make you more prone to developing infections from minor traumatic accidents, particularly for diabetics, who heal more slowly than other people, including foot ulcers and gangrene. Furthermore, muscle atrophy may cause you to develop particular physical disfigurements, such as pes cavus, a condition marked by an abnormally high foot arch, and claw-like deformities in the feet and palms. Treatment The first step in neuropathy treatment should be finding the root cause that's causing the neuropathy. Treatment of diseases such as: - Diabetes
- Guillain-Barre syndrome
- Rheumatoid arthritis
- Sarcoidosis
- Other underlying diseases
Prevents continued nerve damage and in cases heals the damaged nerves. If you are unaware of any underlying disease that is causing the peripheral neuropathy, make sure to let your doctor know of abnormal symptoms. Medication Peripheral neuropathy can be treated with various medications. The first type used to treat mild symptoms are: - Over-the-counter pain medications
In more severe cases: - Opiates
- Narcotic medications
- Anti-seizure medications
A doctor may prescribe a lidocaine patch or anti-depressants to relieve symptoms. Patients should thoroughly discuss neuropathy medication with a doctor before proceeding. Chiropractic/Massage/Physical Therapy Various manual therapies can benefit symptoms in neuropathy treatment. A therapist or chiropractor will perform various manipulation techniques, and teach exercises and stretches to help improve symptoms combined with increased muscle strength/control. A therapist may also recommend braces or splints to improve mobility. Patients should attend all physical therapy sessions to gain maximum benefits. Low-level-laser-therapy LLT The primary and most debilitating symptom of diabetic peripheral neuropathy is a sensation of tingling, prickling, buzzing, pinching, burning, and/or sharp jabbing stabbing pain in the feet. Low-Level Laser Therapy (LLLT) takes information from the receptors on the membrane of the cell and mitochondrion or the engine of the cell. This information reaches the cell's DNA, that directly controls cell function. When cells receive better information, they work better, along with the tissues they make up like: - Bones
- Cartilage
- Tendons
- Ligaments
LLT promotes the healing and regeneration of damaged tissues, and its systemic effects on tissue function are also carried throughout the body by blood and meridians or energy channels. The key basic physiological effects of low-level laser light include: - Increased cell membrane polarization/permeability
- Adenosine-5-triphosphate (ATP) production and respiratory activity
- Enzyme activity
- Collagen and epithelial production
- Capillary formation
- Macrophage (immune system) activity
- Analgesic effects due to elevated endorphin production
- Electrolytic nerve blockage
- Improved blood and lymph flow
- An anti-inflammatory effect from improved circulation and accelerated tissue regeneration
- Increased production of antioxidants
An additional benefit is that the light energy from low-level lasers will only be absorbed by cells and tissues that are not functioning normally and do not go after healthy cells. Low-level laser therapy has the potential of providing an effective means of reducing low back pain that is: - Simple
- Quick
- Non-invasive
- Side-effect free
Acids Supplements like: - Essential acids called ALA (alpha-Lipoic acid)
- GLA (gamma-linolenic acid) and omega-3 fatty acids
These can have a beneficial effect on diabetic peripheral neuropathy. L-Carnitine L-carnitine is a substance that the body makes and stores in the: There have been reports that certain diabetics with neuropathy symptoms could regain regular sensation in the limbs when they increased their consumption of carnitine called acetyl-L-carnitine. - Red meat
- Peanut butter
- Dairy products
Are good dietary sources of this nutrient. Supplements are also available at health food stores and pharmacies and health/wellness clinics. Vitamin Supplements Vitamin deficiencies can result in peripheral neuropathy in some people. Therefore there needs to be a replenishing of vitamins: These can help to decrease symptoms. Recommended dosages are 300mg daily of vitamin E. Doses of the different B vitamins differ, but one option for patients is to take a daily B-complex supplement. Herb Supplements Herbal remedies are an alternative to explore. St. John's Wort, is a herbal supplement that can be taken orally and can reduce the pain. Topical creams that have capsaicin, which is an anti-inflammatory found in chili peppers, can reduce the burning sensation. Acupuncture Acupuncture can be an effective way to manage peripheral neuropathy. Acupuncture uses pressure points throughout the body to realign the body's energy, called the qi or chi. Also, movement therapy is a way to manage the condition. Tai chi and yoga can help: - Align the body
- Mind
- Encourage relaxation
- Distract from the pain
El Paso’s Premier Wellness & Injury Care Clinic. Our services are specialized and focused on injuries and the complete recovery process. Our areas of practice include: As El Paso’s Chiropractic Rehabilitation Clinic & Integrated Medicine Center, we passionately are focused on treating patients after frustrating injuries and chronic pain syndromes. We focus on improving your ability through flexibility, mobility and agility programs custom-tailored for all age groups and disabilities. We want you to live a life filled with more energy, a positive attitude, better sleep, less pain, proper body weight and educated on how to maintain this way of life. We Are Here To Help Get You Healthy & Moving! Health Grades: http://www.healthgrades.com/review/3SDJ4 Facebook Clinical Page: https://www.facebook.com/dralexjimene... Facebook Sports Page: https://www.facebook.com/pushasrx/ Facebook Injuries Page: https://www.facebook.com/elpasochirop... Facebook Neuropathy Page: https://www.facebook.com/ElPasoNeurop... Yelp: El Paso Rehabilitation Center: http://goo.gl/pwY2n2 Yelp: El Paso Clinical Center: Treatment: https://goo.gl/r2QPuZ Clinical Testimonies: https://www.dralexjimenez.com/categor...
Information: Dr. Alex Jimenez – Chiropractor
Clinical Site: https://www.dralexjimenez.com
Injury Site: https://personalinjurydoctorgroup.com Sports Injury Site: https://chiropracticscientist.com Back Injury Site: https://www.elpasobackclinic.com Pinterest: https://www.pinterest.com/dralexjimenez/ Twitter: https://twitter.com/dralexjimenez Twitter: https://twitter.com/crossfitdoctor
Recommend: PUSH-as-Rx ®™
Rehabilitation Center: https://www.pushasrx.com
Facebook: https://www.facebook.com/PUSHftinessa... PUSH-as-Rx: http://www.push4fitness.com/team/
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Scooped by
Dr. Alex Jimenez
October 11, 2019 3:20 PM
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Inflammation is the human body’s natural response to injury, infection, or illness. However, too much inflammation can affect your overall health and wellness, especially when you have inflammation in the brain. Brain inflammation can even affect your mental and emotional well-being. Understanding the causes and symptoms of inflammation in the brain can help determine the best treatment option. Dr. Santosh Kesari describes that brain inflammation can be due to various reasons, including toxins like tobacco or alcohol, diabetes, hypertension, infections, trauma, aging, diet, and stress. “Some inflammation is acute, short-lasting, and possibly reversible but other types of inflammation are chronic and continue to cause brain damage,” Dr. Kesari states. “These may be cumulative and not readily reversible, such as Alzheimer’s disease.” With an overactive immune system, such as in people who have multiple sclerosis or encephalitis which is inflammation in the brain, several people may already be genetically predisposed to experience brain inflammation. Severe inflammation can lead to a variety of symptoms, it may also result in coma, brain damage, or death. The following 7 signs and symptoms may indicate inflammation in the brain. Make sure to seek immediate medical attention if brain inflammation is suspected.
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Scooped by
Dr. Alex Jimenez
October 9, 2019 4:24 PM
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There is plenty of controversies associated with MSG. Researchers believe that the excess consumption of monosodium glutamate can cause asthma, headaches, and even brain health issues. On the other hand, the majority of official sources, including the FDA, claim that MSG is a safe food ingredient. The following article discusses what is monosodium glutamate, or MSG, and its effects on overall health and wellness, exploring both sides of the argument on the food ingredient. What is Monosodium Glutamate (MSG)? MSG is known as monosodium glutamate. It is a common food ingredient that is utilized to enhance flavor in foods. MSG comes from the amino acid, glutamate or glutamic acid, which is one of the most common amino acids found in nature. Glutamate is a non-essential amino acid, which ultimately means that the human body can naturally produce it. Monosodium glutamate also serves a variety of functions in the human body and it is commonly found in almost all types of foods. MSG is a white crystalline powder that looks similar to sugar or table salt. It is also made up of a combination of sodium and glutamic acid, known as sodium salt. The glutamic acid in MSG is created by fermenting starches, however, there is no chemical difference between the glutamic acid in monosodium glutamate and that found in natural foods. The glutamic acid in MSG can be easier to absorb because it isn’t bound inside big protein molecules which the body breaks down.
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Scooped by
Dr. Alex Jimenez
October 4, 2019 5:29 PM
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When compared to other central nervous system (CNS) health issues, chronic neurodegenerative diseases can be far more complicated. Foremostly, because the compromised mitochondrial function has been demonstrated in many neurodegenerative diseases, the resulting problems in energy sources are not as severe as the energy collapse in ischemic stroke. Therefore, if excitotoxicity contributes to neurodegeneration, a different time of chronic excitotoxicity needs to be assumed. In the following article, we will outline what is known about the pathways that may cause excitotoxicity in neurodegenerative diseases. We will specifically discuss that in amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD) and Huntington’s disease (HD) as fundamental examples with sufficiently validated animal models in research studies.
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Scooped by
Dr. Alex Jimenez
October 3, 2019 4:36 PM
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When compared to other central nervous system (CNS) health issues, chronic neurodegenerative diseases can be far more complicated. Foremostly, because the compromised mitochondrial function has been demonstrated in many neurodegenerative diseases, the resulting problems in energy sources are not as severe as the energy collapse in ischemic stroke. Therefore, if excitotoxicity contributes to neurodegeneration, a different time of chronic excitotoxicity needs to be assumed. In the following article, we will outline what is known about the pathways that may cause excitotoxicity in neurodegenerative diseases. We will specifically discuss that in amyotrophic lateral sclerosis (ALS), Alzheimer’s disease (AD) and Huntington’s disease (HD) as fundamental examples with sufficiently validated animal models in research studies.
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Scooped by
Dr. Alex Jimenez
October 1, 2019 3:41 PM
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Excitotoxicity is characterized as an acute insult which causes nerve cell death due to the excessive activation of iGluRs. Acute excitotoxicity plays a fundamental role in a variety of central nervous system (CNS) health issues, including cerebral ischemia, TBI, and status epilepticus. The mechanisms for acute excitotoxicity are different for every health issue. With brain ischemia, L-glutamate-associated and L-aspartate-associated excitotoxicity happen within minutes due to the growth in extracellular cerebral L-glutamate as well as L-aspartate. Because these are also energy-dependent, the abrupt loss of energy due to the shut down of blood flow can ultimately breakdown the neuronal and astroglial membrane. In neurons, membrane depolarization contributes to vesicular discharge. Additionally, energy degradation may even cause a change in their action, therefore, causing L-glutamate and L-aspartate to activate and affect ionic homeostasis which can interrupt EAAT action. The activation of L-glutamate/L-aspartate contributes to excitotoxicity through the over-activation of iGluRs of the NMDA type as demonstrated by the efficiency of NMDA antagonists in animal models of transient cerebral ischemia. In TBI, the mechanical tissue damage and the disruption of the blood-brain barrier can trigger acute secondary neurodegeneration, which, together with neuroinflammation and oxidative stress, is associated with L-glutamate activation from intracellular compartments and, therefore, by acute excitotoxicity. Moveover, acute application of the NMDA antagonist MK801 following TBI ameliorates neuronal loss and long-term behavioral abnormalities, among others. In status epilepticus, continuing the synchronized activity of excitatory neuronal networks as well as the continuous breakdown of restricting mechanisms is the main source of L-glutamate and L-aspartate activation. As the severity of synchronous activity depends upon the involvement of nerve cells into a neuronal system as well as the capability of a neural cell to withstand excess glutamate mainly depends on the expression pattern of iGluRs, a somewhat restricted and maturation-associated degeneration of neuronal populations which is ultimately caused by prolonged epileptic seizures. The significance of excitotoxicity in status epilepticus is shown as NMDA antagonists, such as ketamine, decrease adrenal loss.
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Scooped by
Dr. Alex Jimenez
September 27, 2019 2:51 PM
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The term excitotoxicity was first employed to demonstrate the capability of L-glutamate, in addition to structurally-associated amino acids, to destroy nerve cells, a process which has been suggested to occur in acute and chronic health issues of the central nervous system (CNS). Excitotoxicity is caused by the excess stimulation of iGluRs into a characteristic loss of cell bodies and dendrites as well as post-synaptic structures. There is a substantial degree of variation in the sensitivity of nerve cells compared to the variety of iGluRs which is associated with the specific receptors demonstrated on the nerve cells and their metabolisms. The susceptibility of neurons to excitotoxicity can be affected with age. Acute excitotoxic nerve cell death is believed to occur in reaction to a number of severe insults, including cerebral ischemia, traumatic brain injury (TBI), hypoglycemia, and status epilepticus. However, what about neurodegenerative diseases, such as Alzheimer’s disease? Does chronic excitotoxicity also occur? Could exposure of nerve cells to low but above-average concentrations of L-glutamate, or even glutamatergic neurotransmission through a variety of molecules be involved as previously mentioned, within an extended time period also significantly result in neural cell death? The purpose of the article below is to demonstrate the concepts of acute and chronic glutamate toxicity on the health and wellness of the brain.
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Scooped by
Dr. Alex Jimenez
September 25, 2019 3:32 PM
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For people who love drinking diet sodas, recent research studies have found that diet drinks can increase the risk of stroke and dementia. Although diet drinks have been previously advertised as a much more healthier, low-calorie alternative than regular carbonated drinks, a closer look at the results of these recent research studies ultimately suggests otherwise. One research study, consisting of 2,888 participants, ages 45 and older, in the Framingham Heart Study, asked for diet entries to be filled out up to three times within a seven-year period. According to the research study, participants who said they drank one diet soda a day were roughly twice as likely to have a stroke within the next decade than individuals who didn’t drink diet soda. Drinking regular, sugar-sweetened carbonated drinks did not seem to increase the risk of stroke. However, these types of research studies have only been able to prove an association between diet drinks, stroke and dementia. “Also, only 97 people (about 3 percent) had strokes during the follow-up, which means that only two or even three of those strokes may be associated to drinking diet soda,” stated Dr. Kathryn Rexrode, an associate professor of medicine at Harvard-affiliated Brigham and Women’s Hospital which co-authored a research study on soda intake and stroke risk.
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Scooped by
Dr. Alex Jimenez
September 22, 2019 2:20 PM
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Medicine loves to simplify topics into a good-or-bad dichotomy, and there is no better example than LDL and HDL cholesterol. However, this simplistic way of thinking disregards the beneficial role LDL plays in human physiology, and the complicated variations we see in both LDL and HDL.
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Brain fog can make thinking, understanding, and even remembering basic information challenging. Brain fog is a symptom, rather than a single disorder, commonly associated with vision problems and other health issues like insomnia, anxiety, and even depression. Researchers and healthcare professionals have demonstrated that too much screen time, due to sitting in front of a computer screen or staring at a mobile device for extended periods of time, can ultimately change the brain, causing brain fog and vision problems, among other well-known symptoms. For more information, please feel free to ask Dr. Alex Jimenez or contact us at (915) 850-0900.