Mucosal Immunity
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Mucosal Immunity
The largest immune tissue in the body
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Scooped by Gilbert C FAURE
February 19, 2015 1:33 PM
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Kissing and romance and bacteria with Jason Tetro Feb 14/15

Our "Germ Guy", microbiologist Jason Tetro, reveals how the bacteria we exchange in kisses actually help determine our attraction to people...and how you can change that.
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Scooped by Gilbert C FAURE
February 19, 2015 1:30 PM
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Orally Administrated Lactobacillus pentosus var. plantarum C29 Ameliorates Age-Dependent Colitis by Inhibiting the Nuclear Factor-Kappa B Signaling Pathway via the Regulation of Lipopolysaccharide ...

Orally Administrated Lactobacillus pentosus var. plantarum C29 Ameliorates Age-Dependent Colitis by Inhibiting the Nuclear Factor-Kappa B Signaling Pathway via the Regulation of Lipopolysaccharide ... | Mucosal Immunity | Scoop.it
by Jin-Ju Jeong, Kyung-Ah Kim, Se-Eun Jang, Jae-Yeon Woo, Myung Joo Han, Dong-Hyun Kim To evaluate the anti-inflammaging effect of lactic acid bacteria (LAB) on age-dependent inflammation, we first screened and selected a tumor necrosis factor...
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Scooped by Gilbert C FAURE
February 18, 2015 3:33 PM
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Beryllium Increases the CD14dimCD16+ Subset in the Lung of Chronic Beryllium Disease

Beryllium Increases the CD14dimCD16+ Subset in the Lung of Chronic Beryllium Disease | Mucosal Immunity | Scoop.it
by Li Li, Nabeel Hamzeh, May Gillespie, Jill Elliott, Jieru Wang, Eva Brigitte Gottschall, Peggy M. Mroz, Lisa A.
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Suggested by Société Francaise d'Immunologie
February 18, 2015 2:33 PM
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Serum level of interleukin-21 is elevated in chronic rhinosinusit...: ingentaconnect

“@Aller_MD: Serum level of interleukin-21 is elevated in chronic rhinosinusitis. http://t.co/PkXt2w24eT”
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Scooped by Gilbert C FAURE
February 17, 2015 4:09 PM
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Molecular trigger of inflammatory bowel disease discovered

Molecular trigger of inflammatory bowel disease discovered | Mucosal Immunity | Scoop.it
Cells lining the gut form a barrier that can be breached because of a signaling molecule called tumor necrosis factor (TNF).
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Scooped by Gilbert C FAURE
February 17, 2015 2:20 AM
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New Emphasis on Microbiome in Upper Airways Could Advance URTI ... - Cystic Fibrosis News Today

New Emphasis on Microbiome in Upper Airways Could Advance URTI ... - Cystic Fibrosis News Today | Mucosal Immunity | Scoop.it
Read more about how the Microbiome in the Upper Airways are a Factor in URTI, according to a new Scientific Review.
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Scooped by Gilbert C FAURE
February 16, 2015 2:50 PM
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An Italian cemetery may provide clues on cholera's evolution

An Italian cemetery may provide clues on cholera's evolution | Mucosal Immunity | Scoop.it
A team of archaeologists and other researchers hope that an ancient graveyard in Italy can yield clues about the deadly bacterium that causes cholera.
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Scooped by Gilbert C FAURE
February 16, 2015 1:41 PM
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Diverse roles of STING-dependent signaling on the development of cancer - Nature.com

Diverse roles of STING-dependent signaling on the development of cancer Nature.com The innate immune system provides the first line of defense against pathogen infection though can also influence pathways than can control tumorigenesis.1, 2 For...
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Scooped by Gilbert C FAURE
February 15, 2015 2:58 PM
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Mapping the gut microbiome to better understand its role in obesity

Mapping the gut microbiome to better understand its role in obesity | Mucosal Immunity | Scoop.it
Several recent science studies have claimed that the gut microbiome -- the diverse array of bacteria that live in the stomach and intestines -- may be to blame for obesity. But one expert says it is not that simple.
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Scooped by Gilbert C FAURE
February 15, 2015 2:42 PM
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You Won't Believe What Scientists Found On NYC Subways

You Won't Believe What Scientists Found On NYC Subways | Mucosal Immunity | Scoop.it
Mozzarella. Bubonic plague. Kimchi. Staph. What could these things possibly have in common?
Gilbert C FAURE's insight:

environment only....

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Scooped by Gilbert C FAURE
February 15, 2015 1:02 PM
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Immune profiling in patients with recurrent miscarriage - Journal of Reproductive Immunology

Immune profiling in patients with recurrent miscarriage - Journal of Reproductive Immunology | Mucosal Immunity | Scoop.it
Immune profiling in patients with recurrent #miscarriage.
Journal of Reproductive Immunology
http://t.co/0SYE1KooQs
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Scooped by Gilbert C FAURE
February 14, 2015 2:22 AM
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The Vaginal Microbiota over an 8- to 10-Year Period in a Cohort of HIV-Infected and HIV-Uninfected Women

The Vaginal Microbiota over an 8- to 10-Year Period in a Cohort of HIV-Infected and HIV-Uninfected Women | Mucosal Immunity | Scoop.it
by Supriya D. Mehta, Brock Donovan, Kathleen M. Weber, Mardge Cohen, Jacques Ravel, Pawel Gajer, Douglas Gilbert, Derick Burgad, Greg T.
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Scooped by Gilbert C FAURE
February 13, 2015 3:20 PM
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Site-Specific Glycosylation of Secretory Immunoglobulin A from Human Colostrum - Journal of Proteome Research (ACS Publications)

Site-Specific Glycosylation of Secretory Immunoglobulin A from Human Colostrum - Journal of Proteome Research (ACS Publications) | Mucosal Immunity | Scoop.it
#proteomics: "Site-Specific Glycosylation
of Secretory Immunoglobulin A from Human Colostrum" http://t.co/9mIINJUIcr
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Scooped by Gilbert C FAURE
February 19, 2015 1:30 PM
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Large Scale Aggregate Microarray Analysis Reveals Three Distinct Molecular Subclasses of Human Preeclampsia

Large Scale Aggregate Microarray Analysis Reveals Three Distinct Molecular Subclasses of Human Preeclampsia | Mucosal Immunity | Scoop.it
by Katherine Leavey, Shannon A. Bainbridge, Brian J. Cox
Background Preeclampsia (PE) is a life-threatening hypertensive pathology of pregnancy affecting 3–5% of all pregnancies.
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Scooped by Gilbert C FAURE
February 19, 2015 1:28 PM
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Bovine Milk Proteome in the First 9 Days: Protein Interactions in Maturation of the Immune and Digestive System of the Newborn

Bovine Milk Proteome in the First 9 Days: Protein Interactions in Maturation of the Immune and Digestive System of the Newborn | Mucosal Immunity | Scoop.it
by Lina Zhang, Sjef Boeren, Jos A. Hageman, Toon van Hooijdonk, Jacques Vervoort, Kasper Hettinga In order to better understand the milk proteome and its changes from colostrum to mature milk, samples taken at seven time points in the first 9 days...
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Suggested by Société Francaise d'Immunologie
February 18, 2015 2:34 PM
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Different effects of P. gingivalis LPS and E. coli LPS on the expre... - PubMed - NCBI

Acta Odontol Scand. 2014 Jul;72(5):337-45. doi: 10.3109/00016357.2013.834535. Epub 2013 Nov 21.
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Scooped by Gilbert C FAURE
February 17, 2015 4:13 PM
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When strep throat is something else: Forgotten bacterium is cause of many severe sore throats in young adults

When strep throat is something else: Forgotten bacterium is cause of many severe sore throats in young adults | Mucosal Immunity | Scoop.it
New research suggests that Fusobacterium necrophorum more often causes severe sore throats in young adults than streptococcus — the cause of the much better known strep throat. The findings, suggest physicians should consider F.
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Rescooped by Gilbert C FAURE from Immunology
February 17, 2015 3:39 AM
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Epigenetic modifications of the immune system in health and disease - Nature.com

Epigenetic modifications of the immune system in health and disease Nature.com The epigenetic status of these cells is fine-tuned under physiological conditions; however, its disturbance often results in the development of immunological disorders,...
Gilbert C FAURE's insight:

microbiome and epithelial cells

Gilbert C FAURE's curator insight, February 17, 2015 3:38 AM

Certain environmental factors influence the differentiation and function of immune cells through epigenetic alterations. For example, commensal microbiota-derived metabolites inhibit histone deacetylases to induce regulatory T cells, whereas some infectious agents induce DNA methylation, resulting in the development of cancer. These data imply that epigenetic regulation of host defense cells, which are usually the first to encounter external antigens, is implicated in disease development. Here, we highlight recent advances in our understanding of the molecular mechanisms by which the epigenetic status of immune and epithelial cells is controlled.

Suggested by Société Francaise d'Immunologie
February 17, 2015 2:19 AM
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Differences in interleukin 8 expression in Helicobacter pylori-infe... - PubMed - NCBI

Hum Pathol. 2015 Jan;46(1):129-36. doi: 10.1016/j.humpath.2014.10.006. Epub 2014 Oct 17. Comparative Study; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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Scooped by Gilbert C FAURE
February 16, 2015 1:51 PM
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Frontiers | Transcriptional Factor PU.1 Regulates Decidual C1q Expression in Early Pregnancy in Human | Molecular Innate Immunity

C1q is the first recognition subcomponent of the complement classical pathway, which in addition to being synthesized in the liver, is also expressed by macrophages and dendritic cells. Trophoblast...
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Scooped by Gilbert C FAURE
February 16, 2015 1:17 PM
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Plasticity of Airway Epithelial Cell Transcriptome in Response to Flagellin

Plasticity of Airway Epithelial Cell Transcriptome in Response to Flagellin | Mucosal Immunity | Scoop.it
by Joan G. Clark, Kyoung-Hee Kim, Ryan S. Basom, Sina A. Gharib
Airway epithelial cells (AEC) are critical components of the inflammatory and immune response during exposure to pathogens.
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Scooped by Gilbert C FAURE
February 15, 2015 2:53 PM
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DEFA gene variants associated with IgA nephropathy in a Chinese population - Nature.com

DEFA gene variants associated with IgA nephropathy in a Chinese population
Nature.com
IgA nephropathy (IgAN) is a complex syndrome with high genetic heterogeneity.
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Scooped by Gilbert C FAURE
February 15, 2015 2:36 PM
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Woman becomes OBESE after being given faeces from overweight daughter - Daily Mail

Woman becomes OBESE after being given faeces from overweight daughter - Daily Mail | Mucosal Immunity | Scoop.it
The 32-year-old American woman weighed a stable nine-and-a-half stone before her op. But 16 months later her weight rose to 12 stone, and her BMI was 33 - meeting the medical criteria for obesity.
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Scooped by Gilbert C FAURE
February 14, 2015 4:43 AM
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Serum and Mucosal Antibody Responses to Inactivated Polio Vaccine After Sublingual Immunization Using a Thermoresponsive Gel Delivery System

Serum and Mucosal Antibody Responses to Inactivated Polio Vaccine After Sublingual Immunization Using a Thermoresponsive Gel Delivery System | Mucosal Immunity | Scoop.it
Author: White JA, Blum JS, Hosken NA, et al.This article, published in Human Vaccines & Immunotherapeutics, reports on a preclinical study of an adjuvanted thermoresponsive gel (TRG) presentation of trivalent inactivated poliovirus vaccine to...
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Scooped by Gilbert C FAURE
February 13, 2015 3:21 PM
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Potential effector and immunoregulatory functions of mast cells in ... - PubMed - NCBI

Mucosal Immunol. 2015 Feb 11. doi: 10.1038/mi.2014.131. [Epub ahead of print] REVIEW
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