Mucosal Immunity
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Mucosal Immunity
The largest immune tissue in the body
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Suggested by Société Francaise d'Immunologie
March 14, 2015 10:35 AM
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GM-CSF and uPA are required for Porphyromonas gingivalis-induced alveolar ... - Nature.com

GM-CSF and uPA are required for Porphyromonas gingivalis-induced alveolar ...
Nature.com
Article | PubMed | ISI |; Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M.
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Scooped by Gilbert C FAURE
March 14, 2015 10:24 AM
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Virus-specific T lymphocytes home to the skin during natural dengue infection - Science Magazine

Virus-specific T lymphocytes home to the skin during natural dengue infection
Science Magazine
1Immunology Programme, Life Sciences Institute and Department of Microbiology, National University of Singapore, Singapore 117456, Singapore.
Gilbert C FAURE's insight:

look for dengue in Scoop.it

http://www.scoop.it/search?q=dengue

 

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March 13, 2015 3:27 PM
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Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knock-out model of Sjögren’s syndrome

Ocular Surface Center, Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine, 6565 Fannin Street, Houst
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March 13, 2015 3:26 PM
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Ethanol Impairs Mucosal Immunity Against Streptococcus pneumoniae I... - PubMed - NCBI

Infect Immun. 2015 Mar 9. pii: IAI.02869-14. [Epub ahead of print]
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March 13, 2015 3:25 PM
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Probiotic strain found to have beneficial effect on piglet immune system - FeedNavigator.com

Probiotic strain found to have beneficial effect on piglet immune system - FeedNavigator.com | Mucosal Immunity | Scoop.it
German animal health researchers have found probiotic Enterococcus (E.) faecium strain supports modulation of the immune system in disease threatened pigs but only ‘slightly’.
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March 13, 2015 3:03 PM
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Frontiers | Human Milk Blocks DC-SIGN–Pathogen Interaction via MUC1 | Nutritional Immunology

Beneficial effects of breastfeeding are well-recognized and include both immediate neonatal protection against pathogens, as well as long term protection against allergies and autoimmune diseases.
Gilbert C FAURE's insight:

The present study shows that in human milk, MUC1 is the major milk glycoprotein that binds to the lectin domain of DC-SIGN and prevents pathogen interaction through the presence of Lewis x-type oligosaccharides. Surprisingly, this was specific for human milk, as formula, bovine or camel milk did not show any presence of proteins that interacted with DC-SIGN.

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March 9, 2015 3:33 PM
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Immunocytochemical detection of beta-defensins and cathelicidins in... - PubMed - NCBI

Acta Histochem. 2015 Mar 2. pii: S0065-1281(15)00037-9. doi: 10.1016/j.acthis.2015.02.004. [Epub ahead of print]
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March 8, 2015 9:42 AM
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Immunoregulatory and immunostimulatory responses of bacterial lysates in respiratory infections and asthma - Annals of Allergy, Asthma & Immunology

Results

Bacterial lysates have been observed to induce synergistic TLR-2/6- and TLR-9–dependent innate immunity.... http://t.co/88Voa4roN5
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Rescooped by Gilbert C FAURE from Pharma Biotech Industry Review (Krishan Maggon)
March 8, 2015 9:28 AM
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Oral Administration of Lactococcus lactis Subsp. lactis JCM5805 Enhances Lung Immune Response Resulting in Protection from Murine Parainfluenza Virus Infection

Oral Administration of  Lactococcus lactis  Subsp.  lactis  JCM5805 Enhances Lung Immune Response Resulting in Protection from Murine Parainfluenza Virus Infection | Mucosal Immunity | Scoop.it
When activated by viral infection, plasmacytoid dendritic cells (pDCs) play a primary role in the immune response through secretion of IFN-α. Lactococcus lactis subsp.

Via Krishan Maggon
Krishan Maggon 's curator insight, March 8, 2015 12:57 AM

Citation: Jounai K, Sugimura T, Ohshio K, Fujiwara D (2015) Oral Administration ofLactococcus lactis Subsp. lactis JCM5805 Enhances Lung Immune Response Resulting in Protection from Murine Parainfluenza Virus Infection. PLoS ONE 10(3): e0119055. doi:10.1371/journal.pone.0119055

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March 7, 2015 2:59 PM
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CD1 Antigen Presentation and Autoreactivity in the Pregnant Human U... - PubMed - NCBI

Am J Reprod Immunol. 2015 Mar 4. doi: 10.1111/aji.12375. [Epub ahead of print]
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Suggested by Société Francaise d'Immunologie
March 6, 2015 3:01 PM
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Polarized Epithelial Cells Secrete Interleukin 6 Apically in the Bo... - PubMed - NCBI

Biol Reprod. 2015 Mar 4. pii: biolreprod.115.127936. [Epub ahead of print]
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March 5, 2015 2:42 PM
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Yeast product supplementation modulated humoral and mucosal immunit... - PubMed - NCBI

J Dairy Sci. 2015 Feb 25. pii: S0022-0302(15)00127-7. doi: 10.3168/jds.2014-8469. [Epub ahead of print]
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March 5, 2015 2:40 PM
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DNA methylation differentially regulates cytokine secretion in ging... - PubMed - NCBI

Pathog Dis. 2015 Mar;73(2):1-6. doi: 10.1093/femspd/ftu005. Epub 2014 Dec 4.
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March 14, 2015 10:35 AM
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Potent neutralizing anti-CD1d antibody reduces lung cytokine releas... - PubMed - NCBI

MAbs. 2015 Mar 9:0. [Epub ahead of print]
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March 13, 2015 3:27 PM
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The novel adjuvant dmLT promotes dose sparing, mucosal immunity and longevity of antibody responses to the inactivated polio vaccine in a murine model

Open Access: The novel adjuvant dmLT promotes dose sparing, mucosal immunity & … http://t.co/gUoXL83fe4 #ppnews #polio #vaccine #IPV
Gilbert C FAURE's insight:
double mutant heat-labile enterotoxin from E. coli LT(R192G/L211A)
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March 13, 2015 3:26 PM
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Corticosteroids Okay for IgA Nephropathy Regardless of Renal Function - Renal and Urology News

Corticosteroids Okay for IgA Nephropathy Regardless of Renal Function - Renal and Urology News | Mucosal Immunity | Scoop.it
Corticosteroid treatment decreased proteinuria and the rate of renal function decline and increased renal survival, study finds.
Gilbert C FAURE's insight:

In a retrospective study, Rosanna Coppo, MD, of Turin Hospital in Turin, Italy, and colleagues analyzed data from 1,147 patients with IgAN from the European Validation Study of the Oxford Classification of IgAN (VALIGA) cohort. Physicians prescribed immunosuppression for 46% of the patients. Of these, 98% received CS.

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March 13, 2015 3:25 PM
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Systemic and mucosal immunity in mice elicited by a single immunisa... - PubMed - NCBI

Immunology. 2015 Mar 12. doi: 10.1111/imm.12462. [Epub ahead of print]
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March 13, 2015 3:05 PM
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Oral antigen exposure in newborn piglets circumvents induction of oral ... - BMC Pediatrics

We previously determined that newborn piglets orally gavaged with Ovalbumin (OVA) responded to systemic OVA re-exposure with tolerance; if adjuvants were included in oral vaccine, piglets responded with antibody-mediated immunity (Vet Immunol...
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March 12, 2015 3:51 PM
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The Interaction between Circulating Complement Proteins and Cutaneo... - PubMed - NCBI

PLoS One. 2015 Mar 11;10(3):e0120411. doi: 10.1371/journal.pone.0120411.
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March 9, 2015 3:32 PM
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Intestinal epithelial suppressor of cytokine signaling 3 enhances m... - PubMed - NCBI

Am J Physiol Gastrointest Liver Physiol. 2015 Jan 1;308(1):G25-31. doi: 10.1152/ajpgi.00214.2014. Epub 2014 Nov 6. Research Support, Non-U.S. Gov't
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March 8, 2015 9:40 AM
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Oral antigen exposure in newborn piglets circumvents induction of oral ... - BMC Pediatrics

We previously determined that newborn piglets orally gavaged with Ovalbumin (OVA) responded to systemic OVA re-exposure with tolerance; if adjuvants were included in oral vaccine, piglets responded with antibody-mediated immunity (Vet Immunol...
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March 7, 2015 3:25 PM
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BMC Pulmonary Medicine | Abstract | Hypoxia down-regulates expression of secretory leukocyte protease inhibitor in bronchial epithelial cells via TGF-ß1

Secretory leukocyte protease inhibitor (SLPI) is a protein with anti-protease and antimicrobial properties that is constitutively secreted from the airway epithelium.
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March 7, 2015 3:11 AM
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Respiratory epithelial cells orchestrate pulmonary innate immunity. - PubMed - NCBI

Nat Immunol. 2015 Jan;16(1):27-35. doi: 10.1038/ni.3045. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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March 6, 2015 2:18 PM
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Effect of Dietary Gluten on Dendritic Cells and Innate Immune Subsets in BALB/c and NOD Mice

Effect of Dietary Gluten on Dendritic Cells and Innate Immune Subsets in BALB/c and NOD Mice | Mucosal Immunity | Scoop.it
by Jesper Larsen, Christian Weile, Julie Christine Antvorskov, Kåre Engkilde, Signe Marie Borch Nielsen, Knud Josefsen, Karsten Buschard
The innate immune system is known to play an important role in oral tolerance to dietary antigens.
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March 5, 2015 2:40 PM
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Estimating the Life Course of Influenza A(H3N2) Antibody Responses from Cross-Sectional Data

Estimating the Life Course of Influenza A(H3N2) Antibody Responses from Cross-Sectional Data | Mucosal Immunity | Scoop.it
by Adam J. Kucharski, Justin Lessler, Jonathan M. Read, Huachen Zhu, Chao Qiang Jiang, Yi Guan, Derek A. T.
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