Mucosal Immunity
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Mucosal Immunity
The largest immune tissue in the body
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March 29, 2015 2:13 PM
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Isolation of high-purity myenteric plexus from adult human and mouse ... - Nature.com

Isolation of high-purity myenteric plexus from adult human and mouse ... - Nature.com | Mucosal Immunity | Scoop.it
The enteric nervous system (ENS) orchestrates a broad range of important gastrointestinal functions such as intestinal motility and gastric secretion. The ENS can be affected by environmental factors, diet and disease.
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March 28, 2015 6:03 AM
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Autoimmune host–microbiota interactions at barrier sites and beyond: Trends in Molecular Medicine

RT @ImmunityCP: Ruff & Kreigel look at the microbiota as a driver of autoimmunity @TrendsMolecMed http://t.co/Ye0nYihvY4
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March 25, 2015 3:52 AM
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Role of the intestinal cytokine microenvironment in shaping the intraepithelial lymphocyte repertoire

REVIEW | Role of the Intestinal Cytokine Microenvironment in Shaping the Intraepithelial Lymphocyte Repertoire http://t.co/xphugWUUvu
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March 22, 2015 5:17 AM
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Immunomodulatory Cross-Talk between Conjunctival Goblet Cells and Dendritic Cells

Immunomodulatory Cross-Talk between Conjunctival Goblet Cells and Dendritic Cells | Mucosal Immunity | Scoop.it
by Laura Contreras-Ruiz, Sharmila Masli
Goblet cells are secretory epithelial cells of mucosal tissues that confer protection from environmental agents or pathogens via expression and secretion of soluble mucins.
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March 21, 2015 5:27 AM
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In situ hematopoiesis: a regulator of TH2 cytokine-mediated immunity and inflammation at mucosal surfaces

In situ hematopoiesis: a regulator of TH2 cytokine-mediated immunity and inflammation at mucosal surfaces | Mucosal Immunity | Scoop.it
From BioPortfolio:
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March 20, 2015 9:31 PM
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Shigella IpaB and IpaD displayed on L. lactis bacterium-like particles induce ... - Nature.com

Shigella IpaB and IpaD displayed on L. lactis bacterium-like particles induce ...
Nature.com
A precedent exists for efficient mucosal immunization of newborn mice with Yersinia pestis LcrV displayed on L.
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March 20, 2015 9:23 PM
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A Plant-Derived Multi-HIV Antigen Induces Broad Immune Responses in Orally Immunized Mice - Online First - Springer

A Plant-Derived Multi-HIV Antigen Induces Broad Immune Responses in Orally Immunized Mice - Online First - Springer | Mucosal Immunity | Scoop.it
A Plant-Derived Multi-#HIV Antigen Induces Broad Immune Responses in Orally Immunized Mice @UNAM_MX http://t.co/pMSqYGTogs
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March 19, 2015 4:45 AM
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Milk protein comparison unveils nutritional gems for developing babies

Milk protein comparison unveils nutritional gems for developing babies | Mucosal Immunity | Scoop.it
Human babies appear to need more of a nutritional boost from breast-milk proteins than do infants of one of their closest primate relatives, suggests a study comparing human milk with the milk of rhesus macaque monkeys.
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March 17, 2015 2:10 PM
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Herpes simplex type 2 virus deleted in glycoprotein D protects against vaginal, skin and neural disease

Herpes simplex type 2 virus deleted in glycoprotein D protects against vaginal, skin and neural disease | Mucosal Immunity | Scoop.it
An attenuated Herpes simplex type 2 virus deleted in glycoprotein D can be used as an effective vaccine to provide robust transferable humoral immunity and complete protection in murine intravaginal and skin infection models.
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March 15, 2015 3:19 PM
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Researchers uncover a mechanism linking inhaled diesel pollution and respiratory distress

Researchers uncover a mechanism linking inhaled diesel pollution and respiratory distress | Mucosal Immunity | Scoop.it
Researchers have, for the first time, shown how exhaust pollution from diesel engines is able to affect nerves within the lung.
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March 15, 2015 4:47 AM
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Inflammation in mouth, joints in rheumatoid arthritis

Inflammation in mouth, joints in rheumatoid arthritis | Mucosal Immunity | Scoop.it
Periodontitis shares pathogenic mechanisms with rheumatoid arthritis (RA) and may trigger its onset, scientists say. In a new study, researchers performed joint and dental examinations, determined Porphyromonas gingivalis (P.
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March 14, 2015 10:38 AM
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Snai1 protein plays major role in deciding fate of intestinal stem cells - News-Medical.net

Snai1 protein plays major role in deciding fate of intestinal stem cells - News-Medical.net | Mucosal Immunity | Scoop.it
An international group of researchers has shown that a regulatory protein involved in controlling how cancer spreads through the body also influences the fate of stem cells in the intestine of mice.
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March 14, 2015 10:37 AM
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Radical Vaccine Design Effective Against Herpes Viruses - Howard Hughes Medical Institute

Radical Vaccine Design Effective Against Herpes Viruses - Howard Hughes Medical Institute | Mucosal Immunity | Scoop.it
A new way of thinking challenges standard notions about what a herpes vaccine should look like.
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March 29, 2015 2:12 PM
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Interleukin-17 and interleukin-18 levels in different stages of inflammatory periodontal disease. - PubMed - NCBI

Interleukin-17 and interleukin-18 levels in different stages of inflammatory periodontal disease. - PubMed - NCBI | Mucosal Immunity | Scoop.it
J Indian Soc Periodontol. 2015 Jan-Feb;19(1):14-7. doi: 10.4103/0972-124X.145798.
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March 27, 2015 4:14 PM
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Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T ... - Nature.com

Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T ... - Nature.com | Mucosal Immunity | Scoop.it
At the forefront of medicine, Gene Therapy brings you the latest research into genetic and cell-based technologies to treat disease.
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March 22, 2015 5:18 AM
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Colorectal Mucus Binds DC-SIGN and Inhibits HIV-1 Trans-Infection of CD4+ T-Lymphocytes

Colorectal Mucus Binds DC-SIGN and Inhibits HIV-1 Trans-Infection of CD4+ T-Lymphocytes | Mucosal Immunity | Scoop.it
by Martijn J. Stax, Emily E. I. M. Mouser, Thijs van Montfort, Rogier W. Sanders, Henry J. C. de Vries, Henk L. Dekker, Carolina Herrera, Dave Speijer, Georgios Pollakis, William A.
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March 22, 2015 1:03 AM
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Immune mechanisms at the maternal-fetal interface: perspectives and challenges - Nature.com

Nature.com Immune mechanisms at the maternal-fetal interface: perspectives and challenges Nature.com Another molecule that has an important role at the maternal-fetal interface is AM, a peptide involved in multiple processes including embryonic...
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March 21, 2015 5:25 AM
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Chemokine-mediated immune responses in the female genital tract mucosa - Nature.com

Chemokine-mediated immune responses in the female genital tract mucosa Nature.com The type I mucosa of the upper FGT is lined by a monolayer of tightly joined columnar epithelial cells, providing an impermeable barrier and covered by immunoglobulin...
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March 20, 2015 9:30 PM
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The microbiome and regulation of mucosal immunity - McDermott - 2014 - Immunology - Wiley Online Library

Review Article: The microbiome and regulation of mucosal immunity

http://t.co/rzMjP5hwQx http://t.co/nltDFqbrtB
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March 20, 2015 12:09 PM
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Chemokine-mediated immune responses in the female genital tract mucosa - Nature.com

Chemokine-mediated immune responses in the female genital tract mucosa Nature.com CD4+ T cells have a major role in anti-pathogen responses in the FGT, where, in addition to their helper role for B and CD8+ cytotoxic T-lymphocyte (CTL) responses,...
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March 17, 2015 4:15 PM
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Autoimmunity: Lungs and citrullination : Nature Reviews Rheumatology : Nature Publishing Group

Anti-citrullinated protein antibodies are a distinctive feature of a subset of patients with rheumatoid arthritis (RA). A new report investigates how lung inflammation in patients with chronic obstructive pulmonary disease affects protein citrullination, providing an additional piece of information on the potential link between airway inflammation and RA.
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March 16, 2015 3:07 PM
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Isolation and cytokine analysis of lamina propria lymphocytes from ... - PubMed - NCBI

J Immunol Methods. 2015 Mar 10. pii: S0022-1759(15)00063-0. doi: 10.1016/j.jim.2015.02.012. [Epub ahead of print]
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March 15, 2015 3:16 PM
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GM-CSF and uPA are required for Porphyromonas gingivalis-induced alveolar ... - Nature.com

GM-CSF and uPA are required for Porphyromonas gingivalis-induced alveolar ...
Nature.com
Article | PubMed | ISI |; Matsuki Y, Yamamoto T, Hara K.
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March 14, 2015 10:38 AM
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Warning: the truth behind handshake-sniffing may bum you out - The Guardian

Warning: the truth behind handshake-sniffing may bum you out - The Guardian | Mucosal Immunity | Scoop.it
Other mammals partake in abundant sniffing, often in the anogenital area – so what exactly are we doing when we smell our hand after shaking someone else’s?
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March 14, 2015 10:38 AM
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Alpha-catenin-Dependent Recruitment of the Centrosomal Protein CAP350 to Adherens Junctions Allows Epithelial Cells to Acquire a Columnar Shape

Alpha-catenin-Dependent Recruitment of the Centrosomal Protein CAP350 to Adherens Junctions Allows Epithelial Cells to Acquire a Columnar Shape | Mucosal Immunity | Scoop.it
by Maria P. Gavilan, Marina Arjona, Angel Zurbano, Etienne Formstecher, Juan R. Martinez-Morales, Michel Bornens, Rosa M. Rios
Epithelial morphogenesis involves a dramatic reorganisation of the microtubule cytoskeleton.
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