Mucosal Immunity
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Mucosal Immunity
The largest immune tissue in the body
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Scooped by Gilbert C FAURE
April 21, 2015 2:05 PM
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Analysis of microbiota reveals CRS phenotypes characterized by compositions of bacterial communities

Analysis of microbiota reveals CRS phenotypes characterized by compositions of bacterial communities | Mucosal Immunity | Scoop.it
An analysis of microbiota showed particular chronic rhinosinusitis phenotypes are characterized by distinct compositions of resident bacterial communities that may predict surgical outcomes, according to study results.
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April 20, 2015 1:55 PM
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NEFIGAN Trial of Nefecon for treatment of primary IgA nephropathy meets ... - News-Medical.net

NEFIGAN Trial of Nefecon for treatment of primary IgA nephropathy meets ... - News-Medical.net | Mucosal Immunity | Scoop.it
Pharmalink AB, a specialty pharma company, today announces that the NEFIGAN Trial of Nefecon for the treatment of primary IgA nephropathy has fully met its primary efficacy endpoint at a planned interim analysis and been stopped early with respect...
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Suggested by Société Francaise d'Immunologie
April 18, 2015 4:58 AM
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miR-143 inhibits interleukin-13-induced inflammatory cytokine and mucus production in nasal epithelial cells from allergic rhinitis patients by tar... - PubMed - NCBI

miR-143 inhibits interleukin-13-induced inflammatory cytokine and mucus production in nasal epithelial cells from allergic rhinitis patients by tar... - PubMed - NCBI | Mucosal Immunity | Scoop.it
Biochem Biophys Res Commun. 2015 Jan 30;457(1):58-64. doi: 10.1016/j.bbrc.2014.12.058. Epub 2014 Dec 18. Research Support, Non-U.S. Gov't
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April 17, 2015 3:50 PM
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Unprecedented Germ Diversity Found in Remote Amazonian Tribe - ABC News

Unprecedented Germ Diversity Found in Remote Amazonian Tribe - ABC News | Mucosal Immunity | Scoop.it
In a remote part of the Venezuelan Amazon, scientists have discovered that members of a village isolated from the modern world have the most diverse colonies of bacteria ever reported living in and on the human body.
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Scooped by Gilbert C FAURE
April 15, 2015 2:49 PM
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Adult Non-Cystic Fibrosis Bronchiectasis Is Characterised by Airway Luminal Th17 Pathway Activation

Adult Non-Cystic Fibrosis Bronchiectasis Is Characterised by Airway Luminal Th17 Pathway Activation | Mucosal Immunity | Scoop.it
by Alice C.-H. Chen, Megan L. Martin, Rohan Lourie, Geraint B. Rogers, Lucy D. Burr, Sumaira Z. Hasnain, Simon D. Bowler, Michael A. McGuckin, David J.
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April 15, 2015 2:23 PM
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Changes and clinical significance of peripheral blood helper T lymphocyte and natural killer (NK) cells in unexplained recurrent spontaneous aborti... - PubMed - NCBI

Changes and clinical significance of peripheral blood helper T lymphocyte and natural killer (NK) cells in unexplained recurrent spontaneous aborti... - PubMed - NCBI | Mucosal Immunity | Scoop.it
Clin Exp Obstet Gynecol. 2015;42(1):62-6.
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Scooped by Gilbert C FAURE
April 14, 2015 2:08 PM
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Public Release: 1-Apr-2015 AAO-HNSF updated clinical practice guideline ... - EurekAlert (press release)

Public Release: 1-Apr-2015 AAO-HNSF updated clinical practice guideline ... - EurekAlert (press release) | Mucosal Immunity | Scoop.it
Sinusitis affects about one in eight adults in the United States, resulting in over 30 million annual diagnoses. The direct cost of managing acute and chronic sinusitis exceeds $11 billion per year.
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Suggested by Société Francaise d'Immunologie
April 14, 2015 2:00 PM
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Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury. - PubMed - NCBI

Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury. - PubMed - NCBI | Mucosal Immunity | Scoop.it
Immunity. 2015 Apr 3. pii: S1074-7613(15)00118-1. doi: 10.1016/j.immuni.2015.03.004. [Epub ahead of print]
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Scooped by Gilbert C FAURE
April 12, 2015 3:19 PM
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Sequencing the intestinal microbiome to target therapies - News from the University of Massachusetts

Sequencing the intestinal microbiome to target therapies - News from the University of Massachusetts | Mucosal Immunity | Scoop.it
UMass scientists are sequencing the intestinal microbiome and developing mathematical models to predict which treatments may be most effective.
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April 12, 2015 2:34 PM
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T-lymphocyte phenotype and function triggered by Aggregatibacter actinomycetemcomitans is serotype-dependent - Díaz-Zúñiga - 2015 - Journal of Periodontal Research - Wiley Online Library

T-lymphocyte phenotype and function triggered by Aggregatibacter actinomycetemcomitans is serotype-dependent - Díaz-Zúñiga - 2015 - Journal of Periodontal Research - Wiley Online Library | Mucosal Immunity | Scoop.it
T-Lymphocyte Phenotype and Function Triggered by A. Actinomycetemcomitans Is Serotype-Dependent http://t.co/E8xGi2WGOl
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Scooped by Gilbert C FAURE
April 12, 2015 2:26 PM
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A Highly Focused Antigen Receptor Repertoire Characterizes γδ T Cells That are Poised to Make IL-17 Rapidly in Naive Animals. - PubMed - NCBI

A Highly Focused Antigen Receptor Repertoire Characterizes γδ T Cells That are Poised to Make IL-17 Rapidly in Naive Animals. - PubMed - NCBI | Mucosal Immunity | Scoop.it
Front Immunol. 2015 Mar 23;6:118. doi: 10.3389/fimmu.2015.00118. eCollection 2015.
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Scooped by Gilbert C FAURE
April 12, 2015 3:56 AM
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Microbes help produce serotonin in gut

Microbes help produce serotonin in gut | Mucosal Immunity | Scoop.it
Although serotonin is well known as a brain neurotransmitter, it is estimated that 90 percent of the body's serotonin is made in the digestive tract.
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Scooped by Gilbert C FAURE
April 11, 2015 3:25 PM
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IgA in serum: An old acquaintance as a new prognostic biomarker in Idiopathic Pulmonary Fibrosis - ten Klooster - Clinical & Experimental Immunology - Wiley Online Library

IgA in serum: An old acquaintance as a new prognostic biomarker in Idiopathic Pulmonary Fibrosis - ten Klooster - Clinical & Experimental Immunology - Wiley Online Library | Mucosal Immunity | Scoop.it
IgA is an important immunoglobulin in mucosal immunity and protects the lungs against invading pathogens. The... http://t.co/AkTVUVG5y5
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Scooped by Gilbert C FAURE
April 20, 2015 2:15 PM
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Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life. - PubMed - NCBI

Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life. - PubMed - NCBI | Mucosal Immunity | Scoop.it
BMC Vet Res. 2015 Mar 7;11(1):50.
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Scooped by Gilbert C FAURE
April 19, 2015 1:25 PM
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Anti-mouse CD52 monoclonal antibody ameliorates intestinal epithelial barrier function in interleukin-10 knockout mice with spontaneous chronic col... - PubMed - NCBI

Anti-mouse CD52 monoclonal antibody ameliorates intestinal epithelial barrier function in interleukin-10 knockout mice with spontaneous chronic col... - PubMed - NCBI | Mucosal Immunity | Scoop.it
Immunology. 2015 Feb;144(2):254-62. doi: 10.1111/imm.12366. Research Support, Non-U.S. Gov't
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April 18, 2015 4:46 AM
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The Oral Microbiome: From Bad Bugs to Bad Biofilm Behaviors

The Oral Microbiome: From Bad Bugs to Bad Biofilm Behaviors | Mucosal Immunity | Scoop.it
The Oral #Microbiome: From Bad Bugs to Bad Biofilm Behaviors http://t.co/fJjTRGyxAh #autoimmunity #autoimmune disease
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Scooped by Gilbert C FAURE
April 17, 2015 7:17 AM
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PBP1a-Deficiency Causes Major Defects in Cell Division, Growth and Biofilm Formation by Streptococcus mutans

PBP1a-Deficiency Causes Major Defects in Cell Division, Growth and Biofilm Formation by Streptococcus mutans | Mucosal Immunity | Scoop.it
by Zezhang T. Wen, Jacob P. Bitoun, Sumei Liao Streptococcus mutans, a key etiological agent of human dental caries, lives almost exclusively on the tooth surface in plaque biofilms and is known for its ability to survive and respond to various...
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Scooped by Gilbert C FAURE
April 15, 2015 2:45 PM
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Sinonasal Microbiome Sampling: A Comparison of Techniques

Sinonasal Microbiome Sampling: A Comparison of Techniques | Mucosal Immunity | Scoop.it
by Ahmed Bassiouni, Edward John Cleland, Alkis James Psaltis, Sarah Vreugde, Peter-John Wormald
Background The role of the sino-nasal microbiome in CRS remains unclear.
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Scooped by Gilbert C FAURE
April 14, 2015 2:10 PM
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Enhanced Mucosal Immune Responses Induced by a Combined Candidate Mucosal Vaccine Based on Hepatitis A Virus and Hepatitis E Virus Structural Proteins Linked to Tuftsin

Enhanced Mucosal Immune Responses Induced by a Combined Candidate Mucosal Vaccine Based on Hepatitis A Virus and Hepatitis E Virus Structural Proteins Linked to Tuftsin | Mucosal Immunity | Scoop.it
by Yan Gao, Qiudong Su, Yao Yi, Zhiyuan Jia, Hao Wang, Xuexin Lu, Feng Qiu, Shengli Bi
Hepatitis A virus (HAV) and Hepatitis E virus (HEV) are the most common causes of infectious hepatitis.
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April 14, 2015 2:00 PM
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Secretory hyperresponsiveness and pulmonary mucus hypersecretion. - PubMed - NCBI

Secretory hyperresponsiveness and pulmonary mucus hypersecretion. - PubMed - NCBI | Mucosal Immunity | Scoop.it
Chest. 2014 Aug;146(2):496-507. doi: 10.1378/chest.13-2609. Research Support, Non-U.S. Gov't; Review
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Scooped by Gilbert C FAURE
April 14, 2015 1:52 PM
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Inflammatory Bowel Disease

Inflammatory Bowel Disease | Mucosal Immunity | Scoop.it
A new review article covers the wide range of cancers associated with inflammatory bowel disease and the drugs used to manage them. Surveillance recommendations are presented.
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Scooped by Gilbert C FAURE
April 12, 2015 2:54 PM
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A Single-Cell Breakthrough - Bioscience Technology

A Single-Cell Breakthrough - Bioscience Technology | Mucosal Immunity | Scoop.it
The human gut is a remarkable thing. Every week the intestines regenerate a new lining, sloughing off the equivalent surface area of a studio apartment and refurbishing it with new cells.
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Scooped by Gilbert C FAURE
April 12, 2015 2:30 PM
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Air Pollution Particulate Matter Alters Antimycobacterial Respiratory Epithelial Innate Immunity. - PubMed - NCBI

Air Pollution Particulate Matter Alters Antimycobacterial Respiratory Epithelial Innate Immunity. - PubMed - NCBI | Mucosal Immunity | Scoop.it
Infect Immun. 2015 Apr 6. pii: IAI.03018-14. [Epub ahead of print]
ibtissam.akch's curator insight, November 19, 2025 12:38 PM
This study shows that exposure to fine particulate matter (PM2.5/PM10) induces senescence in lung epithelial cells, reduces key antimicrobial peptides (HBD-2, HBD-3), and enhances M. tuberculosis growth. 

Insight : This report points out that pollution can biologically increase the risk of TB infection and has to be limited in order to improve public health.
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April 12, 2015 2:14 PM
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Portions of female reproductive tract likely to be infected by HIV, shows study - News-Medical.net

Portions of female reproductive tract likely to be infected by HIV, shows study - News-Medical.net | Mucosal Immunity | Scoop.it
A Dartmouth study led by Charles Wira, PhD, with first author Marta Rodriguez-Garcia, MD, PhD, found that some portions of the female reproductive tract (FRT) are more likely to be infected by HIV, particularly the ectocervix compared to the...
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April 11, 2015 3:28 PM
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Glomerular disease: Efficacy of corticosteroids in high-risk IgA nephropathy - Nature.com

Glomerular disease: Efficacy of corticosteroids in high-risk IgA nephropathy Nature.com Corticosteroids are frequently used to treat patients with IgA nephropathy (IgAN) despite a paucity of data to support their use in individuals with...
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