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Immunol Lett. 2015 May 2. pii: S0165-2478(15)00066-8. doi: 10.1016/j.imlet.2015.04.005. [Epub ahead of print] 
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Probiotic Mixture VSL#3 Dampens LPS-Induced Chemokine Expression in Human Dendritic Cells by Inhibition of ... #TNO http://t.co/z73l7YLsLQ
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A University of Colorado Boulder and North Carolina State University-led team discovered 110,000 bacterial and 57,000 fungal groups across the US.
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Mediators Inflamm. 2015;2015:176726. doi: 10.1155/2015/176726. Epub 2015 Apr 8.
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Anecdotal reports of nursing mothers have long suggested that giving milk is a lot easier in second and subsequent pregnancies, compared with a first pregnancy. Now, researchers can explain why.
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Mucosal Immunology is the official publication of the Society of Mucosal Immunology (SMI). It aims to provide a forum for both basic and clinical scientists to discuss all aspects of immunity and inflammation involving mucosal tissues. The journal reflects the interests of scientists studying gastrointestinal, pulmonary, nasopharyngeal, oral, ocular, and genitourinary immunology through the publication of original research articles, scholarly reviews, and timely commentaries, editorials and letters.
Gilbert C FAURE's insight:
The microfold (M) cell residing in the follicle-associated epithelium is a specialized epithelial cell that initiates mucosal immune responses by sampling luminal antigens. The differentiation process of M cells remains unclear due to limitations of analytical methods. Here we found that M cells were classified into two functionally different subtypes based on the expression of Glycoprotein 2 (GP2) by newly developed image cytometric analysis. GP2-high M cells actively took up luminal microbeads, whereas GP2-negative or low cells scarcely ingested them, even though both subsets equally expressed the other M-cell signature genes, suggesting that GP2-high M cells represent functionally mature M cells.
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by Wen-xin Jiang, Yue-jian Hu, Li Gao, Zhi-yan He, Cai-lian Zhu, Rui Ma, Zheng-wei Huang Objective The aim of this study was to examine the influence of various time intervals on the composition of the supragingival plaque microbiome, especially...
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Highlights
• The endometrial immune system plays a role in protection against pathogens and feto-maternal tolerance. • The endometrial immune system varies according to the stage of the menstrual cycle. • Both anti- and pro-tumor immune-related factors are involved in endometrial tumors. • Immune system composition may play a role in patient prognosis and may serve as a target for treatment. • Immune system plays a dual role in both a healthy situation and a tumor. Via Krishan Maggon
Krishan Maggon 's curator insight,
May 4, 2015 2:14 AM
Journal of Reproductive Immunology Volume 109, June 2015, Pages 7–16 Review The immune system in the normal endometrium and implications for endometrial cancer developmentA. Vanderstraetena, S. Tuyaertsa, , , F. Amanta, b doi:10.1016/j.jri.2014.12.006
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Microbiology Professor Jiri Mestecky, M.D., Ph.D., has completed the fourth edition of "Mucosal Immunology," the only comprehensive reference covering...
Gilbert C FAURE's insight:
congrats!
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AM-Derived Type I IFNs Orchestrate Innate Immunity to RSV through Recruitment of Antiviral Monocytes @JexpMed http://t.co/iw7q0NAG9M
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With drug resistance on the rise and the emergence of increasingly deadly viral pathogens, scientists must develop a better understanding of the human immune system and its adaptability in order to take full advantage of it, writes a University at...
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Immune Netw. 2015 Apr;15(2):73-82. doi: 10.4110/in.2015.15.2.73. Epub 2015 Apr 23.
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by Lei Lu, Yueyue Yu, Yuee Guo, Yunwei Wang, Eugene B. Chang, Erika C. Claud
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Immunology. 2015 Apr;144(4):587-97. doi: 10.1111/imm.12414. Research Support, N.I.H., Extramural
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Eur J Immunol. 2015 Mar;45(3):773-9. doi: 10.1002/eji.201444816. Epub 2015 Jan 14. Research Support, Non-U.S. Gov't
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Mucosal Immunology - Table of Contents alert Volume 8 Issue 3 pp 441 - 699 http://t.co/kK50ouUWj7
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Clin Sci (Lond). 2015 May 7. [Epub ahead of print]
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RT @CellPressNews: IBD-causingl bacteria wears PraIgA http://t.co/Pu4kD6ACqT
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Studies of the relationship between the microbiome and the development and function of the immune system are demonstrating novel concepts that could significantly alter the way we treat disease and promote wellness. Several diseases, including inflammatory bowel disease, allergy/asthma, and diabetes, are associated with changes in composition of the microbiome. Recent findings suggest novel complex mechanisms by which the microbiome impacts immune cell development and differentiation. A major implication of these findings is that the composition of microbiome may ultimately affect vaccine efficacy. We explore here the potential role of the microbiome in vaccine responses in the context of our growing understanding of the relationship between the gastrointestinal microbiota, resident immune cell populations, and systemic immunity. Via Dominique Blanchard
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Characterization of Peyer’s patch mononuclear phagocyte system http://t.co/33FxMWJQQg
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Nature.com
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Toll-like receptor gene variants and bacterial vaginosis among HIV-1 infected ...
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Patients are always interested in understanding what they should eat and how it will impact their health. Physicians are just as interested in advancing their understanding of the major health effects of foods and food-related diseases.
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Mycobacterium tuberculosis infection of the 'non-classical immune cell'
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Prog Orthod. 2014 Apr 1;15(1):30. doi: 10.1186/s40510-014-0030-4. Research Support, Non-U.S. Gov't
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