Mucosal Immunity
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Mucosal Immunity
The largest immune tissue in the body
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Suggested by Société Francaise d'Immunologie
October 6, 2015 2:38 AM
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Human rhinovirus induced cytokine/chemokine responses in human airway epithelial and immune cells. - PubMed - NCBI

PLoS One. 2014 Dec 12;9(12):e114322. doi: 10.1371/journal.pone.0114322. eCollection 2014. Research Support, N.I.H., Extramural
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October 3, 2015 2:35 PM
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OraSure Technologies (OSUR) Updates on Significant OraQuick Ebola Rapid ... - StreetInsider.com

OraSure Technologies (OSUR) Updates on Significant OraQuick Ebola Rapid ... - StreetInsider.com | Mucosal Immunity | Scoop.it
orasure technologies (osur) updates on significant oraquick ebola rapid antigen test progress
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Suggested by Société Francaise d'Immunologie
October 1, 2015 3:18 PM
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Interleukin-1 (IL-1) signaling in intestinal stromal cells controls KC/ CXCL1 secretion, which correlates with recruitment of IL-22- secreting neut... - PubMed - NCBI

Infect Immun. 2015 Aug;83(8):3257-67. doi: 10.1128/IAI.00670-15. Research Support, Non-U.S. Gov't
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October 1, 2015 4:14 AM
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B-Cell Responses to Human Bocaviruses 1–4: New Insights from a Childhood Follow-Up Study

B-Cell Responses to Human Bocaviruses 1–4: New Insights from a Childhood Follow-Up Study | Mucosal Immunity | Scoop.it
by Kalle Kantola, Lea Hedman, Laura Tanner, Ville Simell, Marjaana Mäkinen, Juulia Partanen, Mohammadreza Sadeghi, Riitta Veijola, Mikael Knip, Jorma Ilonen, Heikki Hyöty, Jorma Toppari, Olli Simell, Klaus Hedman, Maria Söderlund-Venermo Human...
Gilbert C FAURE's insight:

no IgA?

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September 30, 2015 1:46 PM
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Breast milk composition and infant nutrient intakes during the first 12 months ... - Nature.com

Breast milk composition and infant nutrient intakes during the first 12 months ...
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Scooped by Gilbert C FAURE
September 30, 2015 1:36 PM
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New book chronicles 50 years of clinical research in Singapore - Malay Mail Online

New book chronicles 50 years of clinical research in Singapore - Malay Mail Online | Mucosal Immunity | Scoop.it
SINGAPORE, Sept 28 — In the past, clinical research was sometimes done on researchers’ personal time — and even on their own dime — because of a shortage of resources, and getting published in | Read | Malay Mail Online...
Gilbert C FAURE's insight:

IgA nephropathy inside

published online

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September 29, 2015 4:48 AM
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Herpes vaccine shows promise with prophylactic and the therapeutic efficacy in ... - Outbreak News Today

Herpes vaccine shows promise with prophylactic and the therapeutic efficacy in ... - Outbreak News Today | Mucosal Immunity | Scoop.it
Herpes vaccine shows promise with prophylactic and the therapeutic efficacy in ...
Gilbert C FAURE's insight:

Under the National Institute of Allergy and Infectious Diseases’ (NIAID) preclinical services program, researchers at the Cincinnati Children’s Hospital Medical Center investigated the potential of NanoBio’s intranasal NE glycoprotein vaccine in guinea pig challenge models. Using the prophylactic model, guinea pigs were administered an intranasal NE vaccine then subsequently challenged with the herpes simplex virus-2 (HSV2). In this study, the NE HSV2 vaccine prevented infection and viral latency in 92 percent of animalsvaccinated, versus 8 percent in the no treatment arm. No adverse events were observed in any of the animalsthat received the NE vaccine.

In a separate therapeutic guinea pig study, animals were first infected with HSV2 then vaccinated with the intranasal NE vaccine. During the post-vaccination observation period, the NE HSV2 vaccine reduced recurrent lesions by 64 percent and viral shedding by more than 50 percent, as compared to animals that received no treatment. Of the animals receiving the NE vaccine, 53 percent did not shed any detectable virus. Again, no adverse events were observed in any of the animals that received the NE vaccine.

“The results of these studies demonstrate the potential impact and benefits of intranasal NE vaccines to prevent and treat sexually transmitted diseases

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Scooped by Gilbert C FAURE
September 28, 2015 2:17 PM
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Interaction between rhinovirus and nasal microbiota in early life persists over time

Interaction between rhinovirus and nasal microbiota in early life persists over time | Mucosal Immunity | Scoop.it
The interaction between infections and the microbiota during infancy in the lungs could help provide clues to disease development later in life, according to the findings of a new study.
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September 26, 2015 7:42 AM
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Tumor necrosis factor in colitis: Bad actor or hero?

A common therapeutic target for the treatment of inflammatory bowel disease (IBD) may actually protect against intestinal inflammation by inhibiting pathogenic T-cells, investigators report.
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September 26, 2015 7:20 AM
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Lungs: Facts, Function and Diseases - Live Science

Lungs: Facts, Function and Diseases - Live Science | Mucosal Immunity | Scoop.it
Lungs are an important part of the respiratory system. Adults take 15 to 20 breaths a minute, which comes to around 20,000 breaths a day.
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September 26, 2015 5:22 AM
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Soluble Urokinase Receptor Levels Are Correlated with Focal Segmental Glomerulosclerosis Lesions in IgA Nephropathy: A Cohort Study from China

Soluble Urokinase Receptor Levels Are Correlated with Focal Segmental Glomerulosclerosis Lesions in IgA Nephropathy: A Cohort Study from China | Mucosal Immunity | Scoop.it
by Shui-Ming Guo, Min Han, Mei-Xue Chen, Yong Ning, Guang-Chang Pei, Yue-Qiang Li, Wei Dai, Shu-Wang Ge, Yuan-Jun Deng, Yan-Yan Guo, Xiao-Qing Li, Hermann Haller, Gang Xu, Song Rong Background Soluble urokinase receptor (suPAR) may be involved in...
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September 26, 2015 3:07 AM
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A small-molecule antivirulence agent for treating Clostridium difficile infection - Science Magazine

A small-molecule antivirulence agent for treating Clostridium difficile infection - Science Magazine | Mucosal Immunity | Scoop.it
A small-molecule antivirulence agent for treating Clostridium difficile infection
Science Magazine
Clostridium difficile infection (CDI) is an emerging disease threat caused by use of broad-spectrum antibiotics.
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September 22, 2015 12:24 PM
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The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and ... - Nature.com

The HSP90 inhibitor, 17AAG, protects the intestinal stem cell niche and ...
Nature.com
Highly secretory cells such as Paneth cells are vulnerable to ER stress and thus dependent on a proper UPR for their homeostasis.
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October 5, 2015 8:09 AM
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Intraovarian Transplantation of Female Germline Stem Cells Rescue Ovarian Function in Chemotherapy-Injured Ovaries

Intraovarian Transplantation of Female Germline Stem Cells Rescue Ovarian Function in Chemotherapy-Injured Ovaries | Mucosal Immunity | Scoop.it
by Jiaqiang Xiong, Zhiyong Lu, Meng Wu, Jinjin Zhang, Jing Cheng, Aiyue Luo, Wei Shen, Li Fang, Su Zhou, Shixuan Wang
Early menopause and infertility often occur in female cancer patients after chemotherapy (CTx).
Gilbert C FAURE's insight:

ovarian but impressive

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October 1, 2015 3:20 PM
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Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy. - PubMed - NCBI

Immunity. 2015 Sep 21. pii: S1074-7613(15)00352-0. doi: 10.1016/j.immuni.2015.08.020. [Epub ahead of print]
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October 1, 2015 4:28 AM
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UNM scientists detail progressive organization of immune efficiency in lungfish - UNM Newsroom

UNM scientists detail progressive organization of immune efficiency in lungfish - UNM Newsroom | Mucosal Immunity | Scoop.it
Defense systems against pathogens are a critical life-support system of fish that helps protect against infection.
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October 1, 2015 4:00 AM
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Plasma Cell Gingivitis: Investigate products that cause gingival hypersensitivity - Registered Dental Hygienist

Plasma Cell Gingivitis: Investigate products that cause gingival hypersensitivity - Registered Dental Hygienist | Mucosal Immunity | Scoop.it
Plasma cell gingivitis: Investigating #dentalproducts that cause gingival hypersensitivity http://t.co/R0X4qSo2cq
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September 30, 2015 1:41 PM
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Immune and Inflammatory Cell Composition of Human Lung Cancer Stroma

Immune and Inflammatory Cell Composition of Human Lung Cancer Stroma | Mucosal Immunity | Scoop.it
by G-Andre Banat, Aleksandra Tretyn, Soni Savai Pullamsetti, Jochen Wilhelm, Andreas Weigert, Catherine Olesch, Katharina Ebel, Thorsten Stiewe, Friedrich Grimminger, Werner Seeger, Ludger Fink, Rajkumar Savai Recent studies indicate that the...
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September 30, 2015 12:29 PM
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Synergistic Proinflammatory Responses by IL-17A and Toll-Like Receptor 3 in Human Airway Epithelial Cells

Synergistic Proinflammatory Responses by IL-17A and Toll-Like Receptor 3 in Human Airway Epithelial Cells | Mucosal Immunity | Scoop.it
by Kazutaka Mori, Tomoyuki Fujisawa, Hideki Kusagaya, Katsumasa Yamanaka, Dai Hashimoto, Noriyuki Enomoto, Naoki Inui, Yutaro Nakamura, Masato Maekawa, Takafumi Suda Viral respiratory infections activate the innate immune response in the airway...
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Suggested by Société Francaise d'Immunologie
September 29, 2015 4:45 AM
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Distinct sustained structural and functional effects of interleukin-33 and interleukin-25 on the airways in a murine asthma surrogate. - PubMed - NCBI

Immunology. 2015 Aug;145(4):508-18. doi: 10.1111/imm.12465. Epub 2015 May 17. Research Support, Non-U.S. Gov't
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September 28, 2015 9:58 AM
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Intraspecies Variability Affects Heterotypic Biofilms of Porphyromonas gingivalis and Prevotella intermedia: Evidences of Strain-Dependence Biofilm Modulation by Physical Contact and by Released So...

Intraspecies Variability Affects Heterotypic Biofilms of Porphyromonas gingivalis and Prevotella intermedia: Evidences of Strain-Dependence Biofilm Modulation by Physical Contact and by Released So... | Mucosal Immunity | Scoop.it
by Graziela Murta Barbosa, Andrea Vieira Colombo, Paulo Henrique Rodrigues, Maria Regina Lorenzetti Simionato
It is well known that strain and virulence diversity exist within the population structure of Porphyromonas gingivalis.
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September 26, 2015 7:39 AM
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Characterization and expression of monoclonal antibody-defined molecules on resting and activated bovine αβ, γδ T and NK cells. - PubMed - NCBI

Vet Immunol Immunopathol. 2015 Sep 10. pii: S0165-2427(15)00199-3. doi: 10.1016/j.vetimm.2015.09.002. [Epub ahead of print]
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September 26, 2015 7:09 AM
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HInsurance -Norovirus candidate vaccine induces broad antibody responses in trial participants

HInsurance -Norovirus candidate vaccine induces broad antibody responses in trial participants | Mucosal Immunity | Scoop.it
Norovirus candidate vaccine induces broad antibody responses in trial participants http://t.co/CHQMWLlhh2
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September 26, 2015 3:15 AM
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Glycosylation Effects on FSH-FSHR Interaction Dynamics: A Case Study of Different FSH Glycoforms by Molecular Dynamics Simulations

Glycosylation Effects on FSH-FSHR Interaction Dynamics: A Case Study of Different FSH Glycoforms by Molecular Dynamics Simulations | Mucosal Immunity | Scoop.it
by Biswa Ranjan Meher, Anshuman Dixit, George R. Bousfield, Gerald H. Lushington
The gonadotropin known as follicle-stimulating hormone (FSH) plays a key role in regulating reproductive processes.
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September 26, 2015 3:06 AM
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Intranasal vaccination with killed Leishmania amazonensis promastigotes antigen (LaAg) associated with CAF01 adjuvant induces partial protection in... - PubMed - NCBI

Parasitology. 2015 Sep 23:1-7. [Epub ahead of print]
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