Mucosal Immunity

Technology to predict how our bodies will manage chronic diseases such as Crohn's disease and inflammatory bowel disease promises to accelerate the discovery of new treatments, identify leads for further study, and occasionally uncover hidden...

by M. Ravishankar Ram, Khean Lee Goh, Alex Hwong Ruey Leow, Bee Hoon Poh, Mun Fai Loke, Richard Harrison, Esaki M. Shankar, Jamuna Vadivelu
Helicobacter pylori (H.

by Meng Zhang, Yongxing Chen, Lingzhi Xie, Yuhong Li, Han Jiang, Minquan Du
Despite recent successes in the control of dental caries, the mechanism of caries development remains unclear.

by Jerri Caldeira, Jeremiah Bustos, Julianne Peabody, Bryce Chackerian, David S. Peabody
The possibility of a contraceptive vaccine targeting human chorionic gonadotropin has long been recognized, but never fully realized.

by Hirotaka Matsuzaki, Yu Mikami, Kousuke Makita, Hideyuki Takeshima, Masafumi Horie, Satoshi Noguchi, Taisuke Jo, Osamu Narumoto, Tadashi Kohyama, Hajime Takizawa, Takahide Nagase, Yasuhiro Yamauchi Chronic inflammatory airway diseases, such as...

A group of 48 scientists from 50 US institutions Wednesday called for more ambitious research into the tiny microorganisms that play a huge role in health, energy and farming.
Known as the Unified Microbiome Initiative Consortium (UMIC), the effort aims to vastly improve research on microbiomes, whether they be in the soil, the water or the human gut.
The project would uncover the role of individual microbes—which include fungi, bacteria, viruses, algae and more—and how they communicate with each other, their hosts, and their environment.
The US-based program would have a 10-year timeframe, and could be complemented by a European effort, scientists wrote in the journals Science and Nature.
"Over the past 20 years, new technologies have reshaped our understanding of the essential roles microbes play on our planet," said a statement by Miyoung Chun, executive vice president of science programs at The Kavli Foundation.
"A Unified Microbiome Initiative would develop the transformative tools and research teams we need to harness the power of these communities to improve human health, agricultural productivity, bioenergy production, and environmental stability."
There are believed to be 100 trillion microbes in the human gut, and they are critical to health and development, but scientists are only just beginning to understand why.
Those calling for the new effort hail from the Department of Energy, national laboratories, universities and research institutions.

by Emily G. Notch, Britton C. Goodale, Roxanna Barnaby, Bonita Coutermarsh, Brent Berwin, Vivien F. Taylor, Brian P. Jackson, Bruce A.

UK - New research from the Royal Veterinary College (RVC) could enable cattle to be vaccinated more effectively against bovine viral diarrhoea virus (BVDV), an endemic viral disease which has a considerable economic impact in the UK and elsewhere.

by Elizabeth Martin, Paul D. Ray, Lisa Smeester, Matthew R. Grace, Kim Boggess, Rebecca C. Fry
Preeclampsia is a potentially fatal pregnancy disorder affecting millions of women around the globe.