Mucosal Immunity
34.5K views |
+4 today
 Your new post is loading...
Your new post is loading...
Scoop.it!
Gaithersburg, Md., April 25, 2016 - MedImmune, the global biologics research and development arm of AstraZeneca, today announced that it has achieved a significant scientific milestone by publishing three manuscripts in Nature Immunology that advance...
Scoop.it!
THE INTRA-FAMILY MICROBIAL DYNAMICS By Naseer Sangwan, PhD The gut microbiome (total microbial gene content existing in the gastrointestinal tract) has been established as a significant factor in t…
Scoop.it!
Duke researchers have created a new molecular map of Zika - and say it reveals how the virus stays alive in semen, saliva and urine - and could show them how to target the virus with drugs.
Gilbert C FAURE's insight:
nice pictures, not clear to me yet what is the molecular ligand?
Scoop.it!
Cities have their own distinct microbial communities but these communities don't vary much between offices located in the same city, according to a new study. The work offers insight into what drives the composition of microbes in built environments.
Scoop.it!
Housing lab mice with pet-shop mice gives them more human-like immune systems.
Gilbert C FAURE's insight:
at last! somebody is publishing this experimental setting!!
Scoop.it!
Robert E.W. Hancock, Evan F. Haney & Erin E. Gill AffiliationsCorresponding author Nature Reviews Immunology (2016) doi:10.1038/nri.2016.29 Published online
Gilbert C FAURE's insight:
Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse sequences that are produced by various cells and tissues in all complex life forms. HDPs have important roles in the body's response to infection and inflammation. This Review focuses on human HDPs and explores the diverse immunomodulatory effects of HDPs from a systems biology perspective, which highlights the interconnected nature of the effect (or effects) of HDPs on the host. Studies have demonstrated that HDPs are expressed throughout the body and mediate a broad range of activities, which explains their association with various inflammatory diseases and autoimmune disorders. The diverse actions of HDPs, such as their roles in wound healing and in the maintenance of the microbiota, are also explored, in addition to potential therapeutic applications.
Scoop.it!
Related Articles
Differential capacity for complement receptor-mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte. Mol Oral Microbiol.
Scoop.it!
Clin Exp Immunol. 2016 Apr 16. doi: 10.1111/cei.12801. [Epub ahead of print]
Scoop.it!
TNF superfamily member 13 (TNFSF13) has been identified as a susceptibility gene for IgA nephropathy in recent genetic studies. However, the role of TNFSF13 in the progression of IgA nephropathy remains unresolved.
Scoop.it!
AIDS Res Ther. 2016 Apr 11;13:19. doi: 10.1186/s12981-016-0103-1. eCollection 2016. Review
Scoop.it!
(2015). Age-associated changes of the intestinal epithelial barrier: local and systemic implications. Expert Review of Gastroenterology & Hepatology: Vol. 9, No. 12, pp. 1467-1469. doi: 10.1586/17474124.2015.1092872
|
Scoop.it!
Background Interleukin-33 (IL-33) is a tissue-derived cytokine that is constitutively expressed in epithelial cells of tissues exposed to the environment and plays a role in sensing damage caused by inflammatory diseases.
Scoop.it!
Mucosal Immunology is the official publication of the Society of Mucosal Immunology (SMI). It aims to provide a forum for both basic and clinical scientists to discuss all aspects of immunity and inflammation involving mucosal tissues. The journal reflects the interests of scientists studying gastrointestinal, pulmonary, nasopharyngeal, oral, ocular, and genitourinary immunology through the publication of original research articles, scholarly reviews, and timely commentaries, editorials and letters.
Scoop.it!
Zika virus (ZIKV), formerly a neglected pathogen, has recently been associated with microcephaly in fetuses, and with Guillian–Barré syndrome in adults.
Gilbert C FAURE's insight:
more details on Zika virus structure
Scoop.it!
Author Summary Respiratory syncytial virus (RSV) is the major cause of pneumonia and bronchiolitis among infants and children globally.
Scoop.it!
A review of scientific studies on human breast milk by researchers at Zurich University has suggested the 200 sugars in human breast milk helps to prime a baby's immune system and gut.
Scoop.it!
The center will accelerate research bent on learning more about the internal microbial ecosystems with which we co-exist, and on applying this knowledge to enhance people’s health.
Scoop.it!
Microbial colonization of the infant gastrointestinal tract (GIT) begins at birth, is shaped by the maternal microbiota, and is profoundly altered by antibiotic treatment.
Scoop.it!
Mothers' milk guides the development of neonates' gut microbiota, nourishing a very specific bacterial population that protects the child.
Scoop.it!
PLoS One. 2015 Apr 20;10(4):e0124659. doi: 10.1371/journal.pone.0124659. eCollection 2015. Research Support, Non-U.S. Gov't
Scoop.it!
RT @biomodels: Model of the Month: Model describing the dynamics of mucosal immunity during C.difficile infection at https://t.co/83tYMx7eXV
Scoop.it!
PLoS One. 2016 Apr 14;11(4):e0153045. doi: 10.1371/journal.pone.0153045.
|
