Immunology
195.8K views | +0 today
Immunology
Teaching and Learning Immunology. Information you never would have searched for!
Your new post is loading...
Your new post is loading...
Scooped by Gilbert C FAURE
September 7, 2011 7:52 AM
Scoop.it!

Scientists Develop Prototype Bactericidal Tuberculosis Vaccine that Elicits ... - Genetic Engineering News

Scientists Develop Prototype Bactericidal Tuberculosis Vaccine that Elicits ... - Genetic Engineering News | Immunology | Scoop.it
Scientists Develop Prototype Bactericidal Tuberculosis Vaccine that Elicits ...Genetic Engineering NewsA team at the Albert Einstein College of Medicine's Howard Hughes Medical Institute (HHMI) removed the bacterium's own esx-3 gene region, which...
Gilbert C FAURE's insight:

At the level of immune response, the demonstration that IKEPLUS immunization boosts IL-12 p40 and IFN-γ production suggested that enhanced TH1 cell responses were involved in the increased levels of protective immunity after Mtb challenge. Indeed, mice immunized with either IKE or IKEPLUS showed rapid induction of IL-12 p40 and IFN- γ expression within the first two days of high-dose intravenous challenge with Mtb. These data suggested that the protective responses elicited by IKEPLUS immunization were associated with the induction of TH1-type adaptive immunity, which was supported by the finding that Rag1−/− and IL-12 p40-deficient mice showed no significant change in their high susceptibility to Mtb challenge after immunization with IKEPLUS.

No comment yet.
Scooped by Gilbert C FAURE
September 6, 2011 4:22 AM
Scoop.it!

Acquired Immunity | MEDICAL PPTX

Acquired Immunity | MEDICAL PPTX | Immunology | Scoop.it
MEDICAL PPTX: Acquired Immunity,Free online medical powerpoint presentations for medical students and post graduates (Acquired Immunity: Defensive mechanisms include :
1) Innate immunity (Natural or Non specific)
2) Acquired...)...
No comment yet.
Scooped by Gilbert C FAURE
September 6, 2011 4:19 AM
Scoop.it!

Immunobiology of Organ Transplantation: 0306483289

Immunobiology of Organ Transplantation: 0306483289 | Immunology | Scoop.it
Immunobiology of Organ Transplantation (Price: $253.97, Pages: 672). Isbn: 0306483289, 9780306483288. Publisher: Springer. Publication date: 2004-06-24.
No comment yet.
Scooped by Gilbert C FAURE
September 6, 2011 4:16 AM
Scoop.it!

Immunological effects of rituximab on the human spleen in immune ...

As splenectomy is a cornerstone treatment of ITP, the immune effect of RTX on this major secondary lymphoid organ were investigated in 18 spleens removed from ITP patients that were treated or not with RTX.
No comment yet.
Scooped by Gilbert C FAURE
September 6, 2011 4:12 AM
Scoop.it!

Antiphospholipid antibody syndrome.

Antiphospholipid antibodies are directed against phospholipid-protein complexes and include lupus anticoagulant, anticardiolipin antibodies, and anti-beta-2 glycoprotein I antibodies. Antiphospholipid antibody syndrome is a ...
No comment yet.
Scooped by Gilbert C FAURE
September 6, 2011 4:07 AM
Scoop.it!

Tuberculosis Vaccine Highly Promising

Tuberculosis Vaccine Highly Promising | Immunology | Scoop.it
Previous research had suggested that mycobacteria need esx-3 to protect themselves from their hosts' innate immune systems, a first-line defense against pathogens that responds to invaders quickly, but non-specifically.
No comment yet.
Scooped by Gilbert C FAURE
September 2, 2011 7:58 AM
Scoop.it!

Baruj Benacerraf dies at 90; Nobelist made key discoveries about immune system - Los Angeles Times

Baruj Benacerraf dies at 90; Nobelist made key discoveries about immune system - Los Angeles Times | Immunology | Scoop.it
Los Angeles TimesBaruj Benacerraf dies at 90; Nobelist made key discoveries about immune systemLos Angeles TimesHe was injecting the animals with a specific foreign substance similar to an antigen, intending to provoke an immune response in them.
No comment yet.
Scooped by Gilbert C FAURE
September 2, 2011 7:46 AM
Scoop.it!

Two different projects to use viruses to fight cancer - Next Big Future

Two different projects to use viruses to fight cancerNext Big FutureWild type measles virus attaches to and infects lymphocytes using the receptor CD150 (signaling lymphocyte activation molecule, SLAM).
No comment yet.
Scooped by Gilbert C FAURE
September 2, 2011 7:44 AM
Scoop.it!

Pevion, CSL in therapeutic Candida vaccine agreement - Pharmaceutical Business Review

Pevion, CSL in therapeutic Candida vaccine agreementPharmaceutical Business ReviewPEV7 is a therapeutic vaccine based on a protein antigen, Sap2, a key virulence factor of vulvovaginal candidiasis, presented on the surface of virosomes.
No comment yet.
Scooped by Gilbert C FAURE
August 31, 2011 5:03 AM
Scoop.it!

Symposier - Immunology Course in South Africa - "Innate Immunity."

Symposier - Immunology Course in South Africa - "Innate Immunity." | Immunology | Scoop.it
Uploaded and shared in Youtube by: EinsteinCollegeofMed — Lecture 2 of 14: "Innate Immunity." Harris Goldstein, M.D., director, Einstein-Montefiore Center for AIDS Research, professor of pediatrics and microbiology & immunology and the Charles...
Gilbert C FAURE's insight:

Harris Goldstein, M.D., director, Einstein-Montefiore Center for AIDS Research, professor of pediatrics and microbiology & immunology and the Charles Michael Chair in Autoimmune Diseases, delivers a lecture course in basic immunology organized by the KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH) at the Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa. The goal of this lecture series is to provide HIV investigators with a comprehensive course in immunology. (January 2010).

No comment yet.
Scooped by Gilbert C FAURE
August 29, 2011 6:33 AM
Scoop.it!

Rare immune cell is asset and liability in fighting infection - Washington University in St. Louis News

Rare immune cell is asset and liability in fighting infection - Washington University in St. Louis News | Immunology | Scoop.it
Washington University in St. Louis NewsRare immune cell is asset and liability in fighting infectionWashington University in St. Louis NewsResearchers at Washington University School of Medicine in St.
No comment yet.
Scooped by Gilbert C FAURE
August 29, 2011 6:29 AM
Scoop.it!

*2011 Sale Janeway's Immunobiology 8th Edition

*2011 Sale Janeway's Immunobiology 8th Edition | Immunology | Scoop.it
... Part II: The Recognition of Antigen Chapter 4: Antigen Recognition by B-cell and T-cell Receptors Chapter 5: The Generation of Lymphocyte Antigen Receptors Chapter 6: Antigen Presentation to T Lymphocytes; Part III: The Development of ...
No comment yet.
Scooped by Gilbert C FAURE
August 25, 2011 12:20 PM
Scoop.it!

Immunology Lecture Mini-Course, 3 of 14: Antigen Recognition by T ...

Immunology Lecture Mini-Course, 3 of 14: Antigen Recognition by T ... | Immunology | Scoop.it
www.einstein.yu.edu - Immunology Lecture 3 of 14 Antigen Recognition by T lymphocytes.
Scooped by Gilbert C FAURE
September 6, 2011 4:24 AM
Scoop.it!

Chronic granulomatous disease: a review of the infectious and ...

Specific immune responses include immunoglobulin class switching and secretion by B lymphocytes/plasma cells and T lympho- cyte responses (including antigen recognition, clonal proliferation, and cytokine synthesis resulting in B cell ...
Gilbert C FAURE's insight:
Chronic Granulomatous Disease is the most commonly encountered immunodeficiency involving the phagocyte,and is characterized by repeated infections with bacterial and fungal pathogens, as well as the formation ofgranulomas in tissue. The disease is the result of a disorder of the NADPH oxidase system, culminating in aninability of the phagocyte to generate superoxide, leading to the defective killing of pathogenic organisms. Thiscan lead to infections withStaphylococcus aureus,Psedomonasspecies,Nocardiaspecies, and fungi (such asAspergillusspecies andCandida albicans). Involvement of vital or large organs can contribute to morbidity and/or

mortality in the affected patients.

Scooped by Gilbert C FAURE
September 6, 2011 4:20 AM
Scoop.it!

Amazon.com: Autoimmunity eBook: Andrzej Górski, Hubert Krotkiewski, Michal Zimecki: Kindle Store

Amazon.com: Autoimmunity eBook: Andrzej Górski, Hubert Krotkiewski, Michal Zimecki: Kindle Store (Autoimmunity: This book presents an excellent review of the mechanisms underlying the phenomena of autoimmunit...)...
Scooped by Gilbert C FAURE
September 6, 2011 4:17 AM
Scoop.it!

Utilization of monoclonal antibody-targeted nanomateria... [MAbs. 2011] - PubMed - NCBI

PubMed comprises more than 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Gilbert C FAURE's insight:

Studies utilizing mAb-targeted NMs have shown that they exhibit focused targeting, improved pharmacokinetics and improved "passive" drug delivery via leaky vasculature. Nevertheless, before they can be utilized to treat cancer, potential NM toxicity must be thoroughly investigated. Thus, rigorous testing of NM-mAb conjugates in both in vitro and in vivo systems is underway to determine how NM-mAb conjugates will interact with cells and tissues of the body. In this review, we discuss the broad range of nanomaterials that are under investigation as potential platforms for the presentation of mAbs either as single therapeutics or in combination with other drugs and their advantages and limitations in specifically targeting cancer.

No comment yet.
Scooped by Gilbert C FAURE
September 6, 2011 4:13 AM
Scoop.it!

Antibody Engineering Wars-Nex Paradigm | Nex Paradigm

Antibody Engineering Wars-Nex Paradigm | Nex Paradigm | Immunology | Scoop.it
The market for antibody-drug conjugates (ADC) has mostly been cornered Seattle Genetics and Immunogen. Each boasts a long list of corporate partners and extensive clinical pipeline fueled by collaborations.
No comment yet.
Scooped by Gilbert C FAURE
September 6, 2011 4:08 AM
Scoop.it!

Cellular and Molecular Immunology, 6th Edition » VietHak ...

Cellular and Molecular Immunology, 6th Edition » VietHak ... | Immunology | Scoop.it
Through five best selling editions, readers worldwide have appreciated this books in depth yet straightforward, richly illustrated approach to this complex subject. Now, sweeping updates incorporate the latest discoveries about innate immunity ...
No comment yet.
Scooped by Gilbert C FAURE
September 5, 2011 4:54 AM
Scoop.it!

Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer

Human Solid Tumors Contain High Endothelial Venules: Association with Lymphocyte Infiltration in Breast Cancer http://t.co/hFcOQIc...
No comment yet.
Scooped by Gilbert C FAURE
September 2, 2011 7:49 AM
Scoop.it!

Kidney Transplantation - New Perspectives

Kidney Transplantation - New Perspectives | Immunology | Scoop.it
Dr.(Md) Magdalena Trzcinska, "Kidney Transplantation - New Perspectives" InTech | 2011 | ISBN: 9789533076843 | 334 pages | PDF | 14,7 MB.
No comment yet.
Scooped by Gilbert C FAURE
September 2, 2011 7:45 AM
Scoop.it!

Complement Summary | VCOMSC

I summarized the complement slides. My notes may be in a little more detail than we have to know but it helped me make sense of all the nonsense letter and numbers. Hope it helps! –Ann Dobry. pdf icon Complement pg ...
Scooped by Gilbert C FAURE
September 1, 2011 4:02 AM
Scoop.it!

Gene therapy treats immune disease - Littlehampton Gazette

Gene therapy treats immune diseaseLittlehampton GazetteIt is caused by a mutation in a protein required for the development and differentiation of two types of white blood cell that protect the body from infection, the T and B lymphocyte cells.
No comment yet.
Scooped by Gilbert C FAURE
August 29, 2011 7:33 AM
Scoop.it!

T Lymphocytes Subpopulations in Immunotoxicology | Futuristic SciTech

T Lymphocytes Subpopulations in Immunotoxicology | Futuristic SciTech | Immunology | Scoop.it
T Lymphocytes Subpopulations in Immunotoxicology T Lymphocyte Subpopulations in Immunotoxicology Edited by Ian Kimber ZENECA Pharmaceuticals, Central (T Lymphocytes Subpopulations in Immunotoxicology: T Lymphocytes Subpopulations in Immunotoxicology...
No comment yet.
Scooped by Gilbert C FAURE
August 29, 2011 6:31 AM
Scoop.it!

PSGL-1 positive microparticles in allogeneic stem cell ...

As microparticles (MPs) are released from activated or apoptotic cells, there should be significant numbers of circulating PSGL-1-bearing MPs in the blood of patients undergoing allogeneic stem cell transplantation (alloSCT).
No comment yet.
Scooped by Gilbert C FAURE
August 29, 2011 6:25 AM
Scoop.it!

Mechanisms of Islet Xenograft Rejection: The Role of the Innate ...

Mechanisms of Islet Xenograft Rejection: The Role of the Innate ... | Immunology | Scoop.it
Mechanisms of Islet Xenograft Rejection: The Role of the Innate Immune System Xenotransplantation is a potential solution to addressing the global shortage of.
No comment yet.