AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
May 26, 2015 3:37 PM
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Antigen-based immunotherapy (AIT) for autoimmune and allergic disease. - PubMed - NCBI

Antigen-based immunotherapy (AIT) for autoimmune and allergic disease. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Curr Opin Pharmacol. 2015 May 21;23:11-16. doi: 10.1016/j.coph.2015.05.003. [Epub ahead of print] REVIEW
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Scooped by Gilbert C FAURE
May 26, 2015 2:19 PM
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Genes and Immunity - Abstract of article: Suppression of autoimmunity by CD5+ IL-10-producing B cells in lupus-prone mice

Genes and Immunity is a journal dedicated to functional genetics of the immune response.
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Scooped by Gilbert C FAURE
May 25, 2015 2:13 PM
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Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review

Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review | AUTOIMMUNITY | Scoop.it
RT @Lewis_Lab: "Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: A critical review" http://t.co/oyjKhIhAfI
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Suggested by Société Francaise d'Immunologie
May 25, 2015 12:00 PM
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Aberrant expression of regulatory cytokine IL-35 in patients with systemic lupus erythematosus. - PubMed - NCBI

Aberrant expression of regulatory cytokine IL-35 in patients with systemic lupus erythematosus. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Lupus. 2015 May 11. pii: 0961203315585815. [Epub ahead of print]
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Scooped by Gilbert C FAURE
May 25, 2015 11:53 AM
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Altered balance of interleukin-13/interferon-gamma contributes to lacrimal gland destruction and secretory dysfunction in CD25 knockout model of Sjögren’s syndrome

IntroductionThe lacrimal gland (LG) of the CD25-/- model of Sjögren’s syndrome (SS) has high interleukin (IL)-17, IL-13 and interferon-gamma (IFN-γ) cytokines.
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Scooped by Gilbert C FAURE
May 25, 2015 3:50 AM
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Environmental Basis of Autoimmunity. - PubMed - NCBI

Environmental Basis of Autoimmunity. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Clin Rev Allergy Immunol. 2015 May 22. [Epub ahead of print]
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Scooped by Gilbert C FAURE
May 18, 2015 9:46 AM
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Psychiatric Autoimmunity: N-Methyl-d-Aspartate Receptor IgG and Beyond. - PubMed - NCBI

Psychiatric Autoimmunity: N-Methyl-d-Aspartate Receptor IgG and Beyond. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Psychosomatics. 2015 May-Jun;56(3):227-41. doi: 10.1016/j.psym.2015.01.003. Epub 2015 Feb 4.
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Scooped by Gilbert C FAURE
May 18, 2015 9:45 AM
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Circulating IGF-I and IGFBP-3 in relation to the development of β-cell autoimmunity in young children.

Circulating IGF-I and IGFBP-3 in relation to the development of β-cell autoimmunity in young children. | AUTOIMMUNITY | Scoop.it
Authors: Aleksandr Peet, Anu-Maaria Hämäläinen, Pille Kool, Jorma Ilonen, Mikael Knip, Vallo Tillmann, Discipline: Medicine, Type: Journal Article
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Scooped by Gilbert C FAURE
May 17, 2015 4:44 AM
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Contributions of T Lymphocyte Abnormalities to Therapeutic Outcomes in Newly Diagnosed Patients with Immune Thrombocytopenia. - PubMed - NCBI

Contributions of T Lymphocyte Abnormalities to Therapeutic Outcomes in Newly Diagnosed Patients with Immune Thrombocytopenia. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
PLoS One. 2015 May 15;10(5):e0126601. doi: 10.1371/journal.pone.0126601.
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Scooped by Gilbert C FAURE
May 12, 2015 2:39 PM
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Frontiers | Autoantibodies in Renal Diseases – Clinical Significance and Recent Developments in Serological Detection | B Cell Biology

Autoimmune dysfunctions are the “bête noire” in a range of debilitating nephropathies. Autoimmune-mediated damage to the kidneys can be triggered by autoantibodies directed against specific protein...
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Scooped by Gilbert C FAURE
May 11, 2015 1:40 PM
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Journal of Inflammation | Full text | Innate immunity and monocyte-macrophage activation in atherosclerosis - SnapBuzz

Journal of Inflammation | Full text | Innate immunity and monocyte-macrophage activation in atherosclerosis - http://t.co/rWUhYkRIUW
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Scooped by Gilbert C FAURE
May 11, 2015 1:37 PM
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One step closer to an insulin vaccine for type 1 diabetes - HealthCanal.com

One step closer to an insulin vaccine for type 1 diabetes - HealthCanal.com | AUTOIMMUNITY | Scoop.it
One step closer to an insulin vaccine for type 1 diabetes
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Scooped by Gilbert C FAURE
May 11, 2015 1:04 PM
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Participate in Lupus Foundation of America's May Topic: Antiphospholipid ... - Lupus News Today

Participate in Lupus Foundation of America's May Topic: Antiphospholipid ... - Lupus News Today | AUTOIMMUNITY | Scoop.it
Participate in Lupus Foundation of America’s May topic: antiphospholipid syndrome and lupus anticoagulant.
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Scooped by Gilbert C FAURE
May 26, 2015 2:23 PM
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Tpl2 enzyme may be target for treating autoimmune diseases - HealthCanal.com

Tpl2 enzyme may be target for treating autoimmune diseases - HealthCanal.com | AUTOIMMUNITY | Scoop.it
Tpl2 enzyme may be target for treating autoimmune diseases
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Scooped by Gilbert C FAURE
May 26, 2015 2:19 PM
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The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of ... - Nature.com

Nature.com
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of ...
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Scooped by Gilbert C FAURE
May 25, 2015 2:08 PM
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Neuroimmunology: an expanding frontier in autoimmunity. - PubMed - NCBI

Neuroimmunology: an expanding frontier in autoimmunity. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Front Immunol. 2015 Apr 29;6:206. doi: 10.3389/fimmu.2015.00206. eCollection 2015. Review
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Scooped by Gilbert C FAURE
May 25, 2015 11:54 AM
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J&J picks up where Novo left off with an autoimmune licensing deal - FierceBiotech

J&J picks up where Novo left off with an autoimmune licensing deal - FierceBiotech | AUTOIMMUNITY | Scoop.it
Novo Nordisk, gradually exiting the world of autoimmune R&D, has found a home for one of its former projects, handing a development program over to Johnson & Johnson for an undisclosed sum.
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Scooped by Gilbert C FAURE
May 25, 2015 4:20 AM
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Inflammasomes and human autoimmunity: A comprehensive review

Good summary of #inflammasomes+ #autoimmunity http://t.co/GTJYutXezp http://t.co/jxz3XTPdZc
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Scooped by Gilbert C FAURE
May 25, 2015 3:50 AM
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The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity. - PubMed - NCBI

The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Curr Opin Rheumatol. 2015 May 21. [Epub ahead of print]
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Scooped by Gilbert C FAURE
May 18, 2015 9:45 AM
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The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection. - PubMed - NCBI

The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Immunity. 2015 May 11. pii: S1074-7613(15)00171-5. doi: 10.1016/j.immuni.2015.04.011. [Epub ahead of print]
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Scooped by Gilbert C FAURE
May 17, 2015 4:51 AM
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Suppression of autoimmunity by CD5 + IL-10-producing B cells in lupus-prone ... - Nature.com

Suppression of autoimmunity by CD5 + IL-10-producing B cells in lupus-prone ...
Nature.com
NKT cells were gated as PBS57-CD1d Tetramer+ TCRβ+CD19− and quantified by flow cytometry. (b) Autoantibody levels in the serum of 8–9-month-old mice.
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Suggested by Société Francaise d'Immunologie
May 12, 2015 3:45 PM
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T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells [AUTOIMMUNITY]

T cell cross-reactivity underpins the molecular mimicry hypothesis in which microbial peptides sharing structural features with host peptides stimulate T cells that cross-react with self-peptides, thereby initiating and/or perpetuating autoimmune...
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Scooped by Gilbert C FAURE
May 11, 2015 1:41 PM
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Comparison and evaluation of lupus nephritis response criteria in lupus activity indices and clinical trials

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with diverse manifestations. Although the approval of new therapies includes only one agent in 50 years, a number of promising new drugs are in development.
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Scooped by Gilbert C FAURE
May 11, 2015 1:37 PM
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Drak2 Does Not Regulate TGF-β Signaling in T Cells

Drak2 Does Not Regulate TGF-β Signaling in T Cells | AUTOIMMUNITY | Scoop.it
by Tarsha L. Harris, Maureen A. McGargill
Drak2 is a serine/threonine kinase expressed highest in T cells and B cells. Drak2-/- mice are resistant to autoimmunity in mouse models of type 1 diabetes and multiple sclerosis.
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Scooped by Gilbert C FAURE
May 11, 2015 1:29 PM
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The Nose Holds Clues in Vasculitis - MedPage Today

The Nose Holds Clues in Vasculitis - MedPage Today | AUTOIMMUNITY | Scoop.it
Nasal gene profiling revealed upregulation associated with innate immune system in polyangiitis.
Gilbert C FAURE's insight:

trem-1!

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