AUTOIMMUNITY
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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Suggested by LIGHTING
October 25, 2016 1:15 PM
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Dendritic Cells Regulate Extrafollicular Autoreactive B Cells via T Cells Expressing Fas and Fas Ligand

Dendritic Cells Regulate Extrafollicular Autoreactive B Cells via T Cells Expressing Fas and Fas Ligand | AUTOIMMUNITY | Scoop.it
cDCs negatively regulate extrafollicular B activation and autoantibody production.
Using two cDC ablation systems, Ols et al. observe elevated autoantibody production
in the absence of cDCs. They further show that the regulatory effect of cDCs on B
cells requires Fas and FasL expression by T cells.
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Scooped by Gilbert C FAURE
October 22, 2016 8:41 PM
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Association of anti-sperm antibodies with chronic prostatitis: A systematic review and meta-analysis

Association of anti-sperm antibodies with chronic prostatitis: A systematic review and meta-analysis | AUTOIMMUNITY | Scoop.it
Allergy/Immunology Article: Association of anti-sperm antibodies with chronic prostatitis: A systematic review and meta-analysis
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Scooped by Gilbert C FAURE
October 22, 2016 4:45 AM
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Autoimmune manifestations in aged mice arise from early-life immune dysregulation

Autoimmune manifestations in aged mice arise from early-life immune dysregulation | AUTOIMMUNITY | Scoop.it
Autoimmunity is often driven by the collaboration of autoreactive B cells and T cells, which communicate with each other through antigen presentation, cytokines, and costimulatory molecules such as CD40 and CD40 ligand.
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Scooped by Gilbert C FAURE
October 21, 2016 1:17 PM
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Graves’ Disease - Now@NEJM

Graves’ Disease - Now@NEJM | AUTOIMMUNITY | Scoop.it
Graves’ disease is an autoimmune disorder in which the thyroid is activated by antibodies to the thyrotropin receptor.
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Scooped by Gilbert C FAURE
October 21, 2016 1:55 AM
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Infectious Mononucleosis Triggers Generation of IgG Auto-Antibodies against Native Myelin Oligodendrocyte Glycoprotein. - PubMed - NCBI

Viruses. 2016 Feb 12;8(2). pii: E51. doi: 10.3390/v8020051.
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Scooped by Gilbert C FAURE
October 19, 2016 6:10 AM
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High prevalence of diabetes-specific autoimmunity in first-degree relatives of Sardinian patients with type 1 diabetes

High prevalence of diabetes-specific autoimmunity in first-degree relatives of Sardinian patients with type 1 diabetes | AUTOIMMUNITY | Scoop.it
Diabetes/Metabolism Research and ReviewsCLICK HERE TO READ MORE DETAILS
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Scooped by Gilbert C FAURE
October 17, 2016 9:13 PM
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Tolerogenic immunoreceptor ILT3/LILRB4 paradoxically marks pathogenic autoantibody-producing plasmablasts and plasma cells in non-treated SLE. - PubMed - NCBI

Tolerogenic immunoreceptor ILT3/LILRB4 paradoxically marks pathogenic autoantibody-producing plasmablasts and plasma cells in non-treated SLE. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Int Immunol. 2016 Oct 14. pii: dxw044. [Epub ahead of print]
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Scooped by Gilbert C FAURE
October 15, 2016 10:43 AM
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Celiac Disease Autoimmunity in Patients with Autoimmune Diabetes and Thyroid Disease among Chinese Population

Celiac Disease Autoimmunity in Patients with Autoimmune Diabetes and Thyroid Disease among Chinese Population | AUTOIMMUNITY | Scoop.it
The prevalence of celiac disease autoimmunity or tissue transglutaminase autoantibodies (TGA) amongst patients with type 1 diabetes (T1D) and autoimmune thyroid disease (AITD) in the Chinese population remains unknown.
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Suggested by LIGHTING
October 15, 2016 9:34 AM
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Autoimmunity Reviews

Autoimmunity Reviews | AUTOIMMUNITY | Scoop.it


Humoral and cellular autoimmunity in women with recurrent pregnancy losses and repeated implantation failures: A possible role o

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Scooped by Gilbert C FAURE
October 13, 2016 3:07 PM
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2nd Aarhus Immunotherapy Symposium (AIS2): Autoimmunity - Restoring the Balance

2nd Aarhus Immunotherapy Symposium (AIS2): Autoimmunity - Restoring the Balance | AUTOIMMUNITY | Scoop.it
OrganisersBackgroundTime and placeRegistrationProgrammeFurther informationOrganisersProfessor Niels Jessen, Professor Thomas Vorup-Jensen and Honorary Professor Poul Sørensen, Aarhus University & St...
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Scooped by Gilbert C FAURE
October 12, 2016 10:17 AM
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CU researchers identify genes related to vitiligo

CU researchers identify genes related to vitiligo | AUTOIMMUNITY | Scoop.it
For the past decade, Richard Spritz's lab at the University of Colorado Anschutz Medical Campus has been searching for potential causes of vitiligo, an autoimmune disease that gives ris
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Scooped by Gilbert C FAURE
October 11, 2016 8:50 AM
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Age-Associated B Cells: A T-bet–Dependent Effector with Roles in Protective and Pathogenic Immunity

A newly discovered B cell subset, age-associated B cells, expresses the transcription factor T-bet, has a unique surface phenotype, and accumulates progressively with age. Moreover, B cells with these general features are associated with viral infections and autoimmunity in both mice and humans. In this article, we review current understanding of the characteristics, origins, and functions of these cells. We also suggest that the protective versus pathogenic actions of these cells reflect appropriate versus aberrant engagement of regulatory mechanisms that control the Ab responses to nucleic acid–containing Ags.
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Scooped by Gilbert C FAURE
October 10, 2016 10:07 AM
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Perip7lakin is a target for autoimmunity in asthma. - PubMed - NCBI

Perip7lakin is a target for autoimmunity in asthma. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Respir Res. 2016 Oct 7;17(1):126. LETTER
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Scooped by Gilbert C FAURE
October 24, 2016 2:50 PM
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Beyond pan-B-cell-directed therapy [mdash] new avenues and insights into the pathogenesis of SLE : Nature Reviews Rheumatology : Nature Research

Beyond pan-B-cell-directed therapy [mdash] new avenues and insights into the pathogenesis of SLE : Nature Reviews Rheumatology : Nature Research | AUTOIMMUNITY | Scoop.it
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Scooped by Gilbert C FAURE
October 22, 2016 4:46 AM
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Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. - PubMed - NCBI

Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
J Clin Invest. 2016 Oct 17. pii: 85647. doi: 10.1172/JCI85647. [Epub ahead of print]
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Scooped by Gilbert C FAURE
October 22, 2016 4:39 AM
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Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy. - PubMed - NCBI

Diabetologia. 2016 Jan;59(1):170-5.
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Scooped by Gilbert C FAURE
October 21, 2016 2:00 AM
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JCI - Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity

RT @jclinicalinvest: DNA glycosylase mutations lead to lymphocyte apoptosis that drives #autoimmunity https://t.co/1qIEHZausG @BostonChildr…
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Scooped by Gilbert C FAURE
October 19, 2016 6:10 AM
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Role of Parvovirus B19 in Autoimmunity and Autoimmune Disease

Role of Parvovirus B19 in Autoimmunity and Autoimmune Disease | AUTOIMMUNITY | Scoop.it
Parvovirus B19 infection has been associated with the development of a variety of autoimmune diseases. This article reviews its epidemiology and possible mechanisms involved in disease pathogenesis.
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Scooped by Gilbert C FAURE
October 18, 2016 8:28 PM
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Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial

Regulatory T Cell Responses in Participants with Type 1 Diabetes after a Single Dose of Interleukin-2: A Non-Randomised, Open Label, Adaptive Dose-Finding Trial | AUTOIMMUNITY | Scoop.it
Frank Waldron-Lynch and colleagues investigate immune cell biomarker responses in patients with type 1 diabetes following a single dose of recombinant interleukin-2.
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Scooped by Gilbert C FAURE
October 17, 2016 1:12 PM
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Immune cellular regulation on autoantibody production in pemphigus. - PubMed - NCBI

Immune cellular regulation on autoantibody production in pemphigus. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
J Dermatol. 2015 Jan;42(1):11-7. doi: 10.1111/1346-8138.12697. Review
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Scooped by Gilbert C FAURE
October 15, 2016 10:41 AM
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AARDA - autoimmune related disease information

AARDA - autoimmune related disease information | AUTOIMMUNITY | Scoop.it
American Autoimmune Related Diseases Association (AARDA) is dedicated to eradicating autoimmune diseases and alleviating suffering and socioeconomic impact.
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Scooped by Gilbert C FAURE
October 13, 2016 3:07 PM
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Tiam1/Rac1 complex controls Il17a transcription and autoimmunity. - PubMed - NCBI

Tiam1/Rac1 complex controls Il17a transcription and autoimmunity. - PubMed - NCBI | AUTOIMMUNITY | Scoop.it
Nat Commun. 2016 Oct 11;7:13048. doi: 10.1038/ncomms13048.
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Scooped by Gilbert C FAURE
October 13, 2016 3:46 AM
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Modulating Immunity to Treat Autoimmune Disease — NEJM

Modulating Immunity to Treat Autoimmune Disease — NEJM | AUTOIMMUNITY | Scoop.it
Clinical Implications of Basic Research from The New England Journal of Medicine — Modulating Immunity to Treat Autoimmune Disease
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Scooped by Gilbert C FAURE
October 11, 2016 8:52 AM
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International Conference on Autoimmunity

With enthusiastic support of our Organizing Committee and Editorial Board Member, it’s my pleasure to welcome you to participate in the Autoimmunity-2016 i
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Scooped by Gilbert C FAURE
October 10, 2016 10:09 AM
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Autoimmunity Reviews

Autoimmunity Reviews | AUTOIMMUNITY | Scoop.it

APS - Diagnostics and challenges for the future
V. Pengo, E. Bison, G. Zoppellaro, S. Padayattil Jose, G. Denas, A. Hoxha, A. Ruffatti
Gilbert C FAURE's insight:
APS  in french SAPL
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