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AUTOIMMUNITY
Pathology, Diagnosis and Therapies
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Scooped by Gilbert C FAURE
May 23, 2013 3:01 PM
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Identification of a molecule (Arid5a) involved in the promotion of autoimmunity -- Finding may contribute to potential therapeutics for treating IL-6–dependent diseases — Osaka University

Identification of a molecule (Arid5a) involved in the promotion of autoimmunity -- Finding may contribute to potential therapeutics for treating IL-6–dependent diseases — Osaka University | AUTOIMMUNITY | Scoop.it
RT @osaka_univ_e: [Release] Identification of a molecule (Arid5a) involved in the promotion of autoimmunity -- Finding... http://t.co/f8Y5cuBRcl #OsakaUniv
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Scooped by Gilbert C FAURE
May 22, 2013 3:06 PM
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Innate immunity receptor CD36 promotes cerebral amyloid angiopathy

RT @NatRevNeurol: Study reveals role for CD36 -an innate immunity receptor involved in Aβ trafficking- in cerebral amyloid angiopathy http://t.co/RO5bXh4d (£)
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Scooped by Gilbert C FAURE
May 22, 2013 3:02 PM
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Marker For Aggressive Form Of Rheumatoid Arthritis Found

Marker For Aggressive Form Of Rheumatoid Arthritis Found | AUTOIMMUNITY | Scoop.it
A new finding suggests that hindering a certain destructive enzyme may be the key to treating severe rheumatoid arthritis.
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Scooped by Gilbert C FAURE
May 19, 2013 1:27 PM
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Celiac Disease and Autoimmunity: Review and Controversies - Online First - Springer

Celiac Disease and Autoimmunity: Review and Controversies - Online First - Springer | AUTOIMMUNITY | Scoop.it
Celiac Disease and Autoimmunity: Review and Controversies. http://t.co/0mioNdtSCt
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Scooped by Gilbert C FAURE
May 14, 2013 7:10 AM
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The role of microbes and autoimmunity in the pathogenesis of... : Current Opinion in Rheumatology

Purpose of review: To illustrate how microbes might participate in the pathogenesis of neuropsychiatric illness by triggering the production of autoantibodies that bind to brain targets.
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Scooped by Gilbert C FAURE
May 10, 2013 9:50 AM
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OGT Marks World Lupus Day with Novel Biomarker Panel to Support Earlier SLE ... - SelectScience.net (press release)

OGT Marks World Lupus Day with Novel Biomarker Panel to Support Earlier SLE ... - SelectScience.net (press release) | AUTOIMMUNITY | Scoop.it
OGT Marks World Lupus Day with Novel Biomarker Panel to Support Earlier SLE ...
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Scooped by Gilbert C FAURE
May 7, 2013 6:03 AM
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From classrooms to hospitals: when medicine doesn't have all the answers - Scientific American (blog)

From classrooms to hospitals: when medicine doesn't have all the answers - Scientific American (blog) | AUTOIMMUNITY | Scoop.it
Scientific American (blog) From classrooms to hospitals: when medicine doesn't have all the answers Scientific American (blog) Subjects include anatomy, physiology, pathology, biochemistry, pharmacology, microbiology, immunology, embryology, and...
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Scooped by Gilbert C FAURE
May 6, 2013 5:49 AM
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Rituximab Works in ANCA-Linked Vasculitis - MedPage Today - MedPage Today

Rituximab Works in ANCA-Linked Vasculitis - MedPage Today - MedPage Today | AUTOIMMUNITY | Scoop.it
Rituximab Works in ANCA-Linked Vasculitis - MedPage Today MedPage Today WASHINGTON -- Rituximab given as adjunctive therapy to children with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis dramatically lowered the dosage of...
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Scooped by Gilbert C FAURE
May 3, 2013 2:13 PM
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This week in BMC Medicine: autoimmunity, atherosclerosis and adjuvants

This week in BMC Medicine: autoimmunity, atherosclerosis and adjuvants | AUTOIMMUNITY | Scoop.it
Systemic lupus erythematosus (SLE), commonly known as “lupus”, is an autoimmune disease that can affect any of the body’s organs or tissues.
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Scooped by Gilbert C FAURE
May 3, 2013 1:49 PM
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JCI - A disease-associated PTPN22 variant promotes systemic ...

Aged knockin mice exhibited effector T cell expansion and transitional, germinal center, and age-related B cell expansion as well as the development of autoantibodies and systemic autoimmunity. Further, PEP-R619W ...
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Scooped by Gilbert C FAURE
May 2, 2013 3:00 PM
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Autoimmune Hemolytic Anemia and Nodular Lymphocyte ...

Autoimmune Hemolytic Anemia and Nodular Lymphocyte ... | AUTOIMMUNITY | Scoop.it
The most common diseases underlying warm antibody autoimmune hemolytic anemia (AIHA) are lymphoproliferative disorders and autoimmune diseases. Among the former, AIHA has been associated with chronic lymphocytic leukemia, ...
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Scooped by Gilbert C FAURE
April 29, 2013 6:56 AM
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[1304.7193] Vitamin D sensitivity to the immune responses and autoimmunity: A chemical network model study

Vitamin D sensitivity to the immune responses and autoimmunity: A chemical network model study. (arXiv:1304.719... http://t.co/UdKX8L5Ay4
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Scooped by Gilbert C FAURE
April 28, 2013 3:14 AM
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Research: Myelin antibodies predicting MS - Multiple Sclerosis ...

Research: Myelin antibodies predicting MS - Multiple Sclerosis ... | AUTOIMMUNITY | Scoop.it
Because autoantibodies may contribute to the pathogenesis of both diseases, we sought to identify autoantibody biomarkers that are capable of distinguishing them. Methods: We used custom antigen arrays to profile ...
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Scooped by Gilbert C FAURE
May 23, 2013 3:00 PM
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Cognitive decline in a patient with anti-glutamic acid decarboxylase autoimmunity; case report | Case summary | Cases Database

Cognitive decline in a patient with anti-glutamic acid decarboxylase autoimmunity; case report | Case summary | Cases Database | AUTOIMMUNITY | Scoop.it
A continuously-updated, freely-accessible case report database allowing users to interactively explore data from peer-reviewed case reports.
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Scooped by Gilbert C FAURE
May 22, 2013 3:04 PM
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Transient Headache and Neurological Deficits with Cerebrospinal Fluid Lymphocytosis Associated with IgM Antibodies to the Epstein-Barr Virus Viral Capsid Antigen

Transient Headache and Neurological Deficits with Cerebrospinal Fluid Lymphocytosis Associated with IgM Antibodies to the Epstein-Barr Virus Viral Capsid Antigen | AUTOIMMUNITY | Scoop.it
Case Reports in Neurological Medicine is a peer-reviewed, open access journal that publishes case reports in all areas of neurological medicine.
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Scooped by Gilbert C FAURE
May 22, 2013 2:46 PM
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Newly discovered immune protein has potential to stop or reverse type 1 diabetes - News-Medical.net

Newly discovered immune protein has potential to stop or reverse type 1 diabetes
News-Medical.net
The research was published today in the journal Nature Immunology.
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Scooped by Gilbert C FAURE
May 14, 2013 1:57 PM
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Frontiers | Anti-C1q Autoantibodies, Novel Tests, and Clinical Consequences | Frontiers in Molecular Innate Immunity

Frontiers | Anti-C1q Autoantibodies, Novel Tests, and Clinical Consequences | Frontiers in Molecular Innate Immunity | AUTOIMMUNITY | Scoop.it
Frontiers | Anti-C1q Autoantibodies, Novel Tests, and Clinical Consequences | Frontiers in Molecular Innate Immunity publishes articles on the most outstanding discoveries across the research spectrum of Frontiers | Anti-C1q Autoantibodies, Novel...
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Rescooped by Gilbert C FAURE from Lung Cancer Research Digest
May 11, 2013 7:36 AM
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Antibody Repertoire in Paraneoplastic Cerebellar Degeneration and Small Cell Lung Cancer

The goal of this study is to determine whether patients with paraneoplastic cerebellar degeneration (PCD) and small-cell lung cancer (SCLC) have a specific repertoire of antibodies, if SOX1 antibodies (SOX1-ab) can predict the presence of SCLC, and if antibodies to cell surface antigens occur in this syndrome.

 

VGCC-ab and SOX1-ab occur tightly associated. SOX1-ab are predictors of SCLC in ataxia patients with a specificity of 100% and sensitivity of 49%.

 


Via Cancer Commons
Cancer Commons's curator insight, April 3, 2013 4:29 PM

Sabater L, Höftberger R ... Dalmau J, Graus F, PLoS One, Mar 25, 2013

Scooped by Gilbert C FAURE
May 10, 2013 4:21 AM
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Foxp3+ T-regulatory cells require DNA methyltransferase 1 ... - Blood

Foxp3+ T-regulatory cells require DNA methyltransferase 1 ... - Blood | AUTOIMMUNITY | Scoop.it
Foxp3 expression is increased by DNMT inhibitors and may have potential utility in efforts to develop Foxp3+ Tregs for cellular therapy. Dnmt1 deletion impairs Treg function and results in lethal autoimmunity, such that use of ...
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Scooped by Gilbert C FAURE
May 6, 2013 1:44 PM
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Abstract - The Journal of Immunology

Abstract - The Journal of Immunology | AUTOIMMUNITY | Scoop.it
Address correspondence and reprint requests to Dr. Dwight H. Kono, Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, IMM-3, La Jolla, CA 92037.
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Scooped by Gilbert C FAURE
May 4, 2013 1:35 AM
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Metaanalysis of the Association of Smoking and PTPN22 R620W Genotype on Autoantibody Status and Radiological Erosions in Rheumatoid Arthritis

Association of Smoking and PTPN22 R620W on Autoantibody Status and Rad. Erosions in Rheumatoid Arthritis. #mdart #md http://t.co/jbGiUJkdfk
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Scooped by Gilbert C FAURE
May 3, 2013 1:51 PM
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JCI - Autoimmunity risk alleles: hotspots in B cell regulatory ...

Autoimmunity is the consequence of the combination of genetic predisposition and environmental effects, such as infection, injury, and constitution of the gut microbiome. In this edition of the JCI , Dai et al.
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Scooped by Gilbert C FAURE
May 2, 2013 3:09 PM
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Circulating autoantibody to ABCC3 may be a potential biomarker for esophageal squamous cell carcinoma

Circulating autoantibody to ABCC3 may be a potential biomarker for esophageal squamous cell carcinoma | AUTOIMMUNITY | Scoop.it
Oncology Medical Article: Circulating autoantibody to ABCC3 may be a potential biomarker for esophageal squamous cell carcinoma (Circulating autoantibody to ABCC3 may be a potential biomarker for esophageal squamous cell carcinom...
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Scooped by Gilbert C FAURE
May 1, 2013 9:55 AM
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Fluorescent proteins light up the where and when of autoimmune disease (MS) - Examiner.com

Fluorescent proteins light up the where and when of autoimmune disease (MS) - Examiner.com | AUTOIMMUNITY | Scoop.it
Examiner.com
Fluorescent proteins light up the where and when of autoimmune disease (MS)
Examiner.com
*above photograph: (at top) A T lymphocyte is activated after contact with a phagocytic cell.
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Scooped by Gilbert C FAURE
April 28, 2013 10:46 AM
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Complement and autoimmunity. [Immunol Res. 2013] - PubMed - NCBI

PubMed comprises more than 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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