Anti-Th/To autoantibodies have been recognized as serological markers of systemic sclerosis (SSc) for more than 20 years. However, validated immunoassay kits to test this specificity have not been commercially available.
Whether autoantibody-antigen interactions can trigger signaling pathways (such as p38 MAPK) that are tightly linked to the secretion of inflammatory mediators which may perpetuate inflammation and tissue damage in pemphigus remains unclear.
Anti-nuclear antibodies are autoantibodies that bind to contents of the cell nucleus. In normal individuals, the immune system produces antibodies to foreign...
The expression of micro-RNAs in peripheral blood mononuclear cells from primary biliary cirrhosis patients (The expression of micro-RNAs in peripheral blood mononuclear cells from primary biliary cirrhosis patients
Objective: The aim of the present study was to evaluate a panel of different antibody assays, including second-generation antigliadin kits, in a local paediatric population thought to be at risk for coeliac disease (CD).
Tiny RNA Molecules Could Have Medical Applications Science Daily (press release) He and his colleagues also plan to investigate methods for manipulating miR-17~92s and their TFH cell-related pathways, in order to boost antibody responses -- to...
In a prospective birth cohort comprising children with HLA-conferred susceptibility to type 1 diabetes (T1D) the pattern of autoantibody appearance was analyzed in 520 children with advanced β-cell autoimmunity associated ...
Vitamin D insufficiency has been implicated in autoimmunity. ChIP-seq experiments using immune cell lines have shown that vitamin D receptor (VDR) binding sites are enriched near regions of the genome associated with autoimmune diseases.
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Literature Review: Very Platonic Genetic Engineering News The first proof-of-concept experiments involved mapping the interactome for LYN kinase, identifying protein targets for antibodies from autoimmune disease patients, and finally, profiling...
Frontiers | The role of type 1 interferon in systemic sclerosis | Frontiers in Molecular Innate Immunity publishes articles on the most outstanding discoveries across the research spectrum of Frontiers | The role of type 1 interferon in systemic...
Most kidney disorders involve some degree of inflammation, i.e. induction of pro-inflammatory mediators and leukocyte recruitment. But what are the factors that determine inflammation as a trigger or a consequence of kidney injury?
The Journal of Autoimmunity publishes papers related to the diverse aspects of autoimmunity: the mechanism of self-recognition, regulation of... (Journal of Autoimmunity: Impact Factor increases from 7.368 to 8.145!
Autoimmunity Reviews will publish up-to-date, structured reviews on diverse topics in autoimmunity, written by first-class experts in the field. The... (Autoimmunity Reviews Impact Factor leaps from 6.624 to 7.975!
All the Live Online Radio Stations for Ghanaians and Abroad (The First Lady, Mrs Lordina Dramani Mahama, on Saturday joined ShareCare Ghana to celebrate its fifth anniversary...
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