🔷 Une étude de l’Office of Health Economics (OHE) montre que les programmes de vaccination des adultes génèrent jusqu’à 19 fois leur coût initial, soit un bénéfice net moyen estimé à 4 637 $ US par vaccination complète lorsqu’on tient compte de l’ensemble des effets économiques et sociaux.

L’analyse a porté sur quatre vaccins destinés aux adultes :

✅ Grippe saisonnière : prévient les formes graves, les hospitalisations et les pertes de productivité liées aux arrêts de travail.

✅ Pneumocoque : protège contre les pneumonies, septicémies et méningites, particulièrement graves chez les personnes âgées.

✅ Virus respiratoire syncytial (VRS) : réduit les bronchiolites et infections respiratoires aiguës, responsables d’hospitalisations coûteuses chez les sujets fragiles.

✅ Zona : évite les douleurs chroniques (névralgies post-zostériennes) et la perte de qualité de vie qu’elles entraînent.

🔹L’étude a été menée dans 10 pays représentant différents systèmes de santé : Australie, Brésil, France, Allemagne, Italie, Japon, Pologne, Afrique du Sud, Thaïlande et États-Unis.

🔹Les résultats montrent que ces programmes de vaccination allègent significativement la pression sur les systèmes de santé en réduisant les consultations, hospitalisations et complications évitables, tout en soutenant la productivité économique grâce au maintien d’une population active en bonne santé.

🔹Les auteurs soulignent que les retombées socio-économiques sont comparables à celles observées pour la vaccination infantile, mais que l’accès aux vaccins pour adultes reste inégal et souvent exclu des calendriers nationaux de vaccination.

🔹Ils notent aussi un manque de données homogènes et d’outils standardisés pour évaluer l’impact complet, ce qui conduit probablement à sous-estimer la valeur réelle de la vaccination des adultes.

#vaccination #prévention #santépublique #économie #vaccins

God help us all, look who's clutching Rosary beads in the January edition of The Atlantic !
This makes a mockery of the Catholic faith & my devout late Mom is turning over in her grave! | 50 comments on LinkedIn

Concerned about ignorance ? Ouf…

La prochaine pandémie n’attendra pas : sommes-nous prêts ?

Dans un éditorial paru dans Nature, l’attention se tourne désormais non pas uniquement vers quel agent pathogène pourrait déclencher la prochaine pandémie, mais surtout vers comment la science et la société seront capables d’y répondre ; et à quelle vitesse.


Voici ce qu’il est pertinent de retenir :
🦠 Il n’est plus suffisant de repérer le virus : l’urgence est de disposer de pipelines intégrés permettant d’identifier, tester, développer et produire en quelques mois des diagnostics, traitements ou vaccins efficaces.
🦠 Le concept de "100 jours" se dessine : du moment du signal d’alerte jusqu’à la disponibilité d’une contre-mesure, le temps doit être drastiquement réduit.
🦠 L’anticipation passe par des approches intégrées : veille des pathogènes dans les réservoirs animaux, intelligence artificielle (comme le modèle CoVFit mentionné dans l’éditorial) pour modéliser le risque, articulation recherche-industrie-régulation.
🦠 La recherche collaborative, interdisciplinaire, et la conversion rapide des découvertes en application clinique ou publique (illustrées par l’exemple du centre UTOPIA) se révèlent des leviers clés pour limiter l’impact humain, social et économique.


En conclusion, dans un monde où les menaces émergentes ne suivent aucun calendrier, l’enjeu n’est plus seulement d’identifier la prochaine épidémie, mais de savoir si nous serons capables d’y répondre suffisamment vite lorsque celle-ci surviendra.

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https://lnkd.in/d-r-EJ87

#PrepareLaProchaineCrise #Innovation #R&D #Recherche #PipelineRapide #ScienceTranslational #Anticipation

The Unbiased Science 'Difficult Conversations' series is one to bookmark for talking points for open and respectful conversations around the challenging questions that arise about science, health, and vaccines.
The collaborative team at Unbiased Science is one of the many things I am thankful for this holiday season 💕

Vaccines & Vaccinations: A Future Agenda for Social Sciences & Policy

24 November 2025
St Cross College, University of Oxford
Hosted by the Vaccines & Society Unit (VAS)

I’m very happy to share that I’ll be joining an incredible group of colleagues at this workshop, which brings together 17 scholars from 16 countries as part of the Forum for Vaccine Social Science (FOVAS).

The event will open a reflexive and forward-looking conversation on how the social sciences can contribute to the future of vaccination—exploring questions of trust, equity, sovereignty, and the social and political lives of vaccines.

👉 Open to invitees (in person or online)
🔗 Register here: https://lnkd.in/de8Tjs-k 
More details: https://lnkd.in/d5BJqH2y

Excited to exchange ideas with an inspiring interdisciplinary group — and to think together about what a truly social future for vaccines might look like. 💬💭
#Vaccines #SocialScience #GlobalHealth #STS #Policy #FOVAS #Oxford

When federal agencies fall short, scientific accountability must rise.

The Vaccine Integrity Project led by the University of Minnesota aggregated results from 590 studies to independently assess vaccine safety and effectiveness — providing clarity where political guidance falters.

Read https://lnkd.in/d7k2cd6A
#ScienceIntegrity #IndependentReview #VaccineTrust #PublicHealth #DataDriven

Did you know the polio vaccine’s package insert includes detailed information on ingredients, reported adverse reactions, and how the vaccine was evaluated?

It’s a valuable resource for parents who want to understand more than just the basics.

Learn more about the polio vaccine here: picdata.org/polio-dis/

#vaccines

Éradication is always an objective we should strive for in any disease. One new disease that should be eliminated is vaccine hesitancy. Through sharing of knowledge, putting forth an approach based on social and moral objectives in a constructive manner without judgement, while rebuilding trust in healthcare structures, we can tackle this issue. A recent analysis by the Cochrane review on HPV vaccine hesitancy provided insight on parents and children’s views on such and came some directions as to potential solutions. There are multiple contexts, processes and meanings that may shape HPV vaccination. These include social, political, economic, ideological, moral as well as biological factors.
Parents’ and adolescents’ views and practices around the vaccine were influenced by wider sociocultural beliefs about adolescence, sexuality, gender, parenting and health. In many communities, HPV-related infections are linked to ideas of “immoral” sexual behavior, such as promiscuity. This stigma can make the vaccine feel unnecessary, or even shameful. 


https://lnkd.in/eqsKJHRn

Yuck! I need to bathe after reading this! See comments... | 12 comments on LinkedIn

📄 A new study explores the relationship between immunization budgets and vaccine coverage across 9 antigens in 19 low- and lower-middle-income countries analyzed data from UNICEF’s newly released Global Immunization Budget Database for 2021-2024.

📈 A one percentage point increase in the immunization budget was associated with a 0.42% increase in DTP1 coverage growth rate when controlling the years. Other antigens, including DTP3, BCG, MCV1, POL3, IPV1, and PCV3, also showed positive but non-significant trends.

💡The author, Hao-Kai TSENG, highlights that the Global Immunization Budget Database is a breakthrough in immunization economics, leveraging AI to extract and categorize scattered line items from national budget documents, and providing an early outlook into governmental priorities.

Find out more here: https://lnkd.in/e878mR9n

Why do vaccines seem to work better in rich countries than in poor ones?

Our new Lancet Microbe paper from the HypoVax Global consortium shows that this inequality is real. Children in low and middle income countries often have weaker responses to several common vaccines, and rural communities are hit even harder.

My part was to help track which studies actually shared immunological or omics data. The imbalance was obvious. Almost all public datasets come from Europe and the US, while the places where vaccines perform the worst barely show up.

So we are trying to understand a problem that mainly affects poorer populations using data that come mostly from wealthier ones. HypoVax Global is working to change this by building collaborations, generating better data in underrepresented regions, and giving us a clearer picture of how to reduce this gap.

Cheryl Hines, in the past, used to speak up against preventable diseases and harm to children from them.
https://lnkd.in/gWMns9h5

Important reminder as a third (unvaccinated) baby in Kentucky died from whooping cough this year.

Thank you to Sarah Despres who alerted me to that when she shared it on twitter: https://lnkd.in/gipGteKd

Venez nombreux

Told us never to trust him on scientific and medical advices. But still providing some…And based on wrong data… RFK Jr targeted scientists who have published studies showing aluminum adjuvants are safe. In August, Kennedy denounced a large Danish study finding no link between aluminum in vaccines and childhood disease, calling it a "deceitful propaganda stunt" and demanding its retraction. The Annals of Internal Medicine rejected the claim and refused to retract the study.

And, regarding the upcoming advisory panel meeting, HHS spokesperson Emily HIlliard said ACIP "is independently reviewing the full body of evidence on adjuvants and other vaccine components to ensure the highest safety standards."

https://lnkd.in/eiRHX_tv

Babies are dying of whooping cough across the US... and it is largely preventable.

We’ve had more than 25,000 pertussis cases this year so far. Cases are on track to surpass 2024 (a year that already saw a fivefold jump from the year before). In the first three months of 2025 alone, the U.S. logged 6,600 cases — 4× the same period in 2024 and 25× 2023!

Deaths have occurred in several states: three unvaccinated infants in Kentucky, two infants in Louisiana (we are not sure of vaccination status), and a child under 5 in Washington state who had received some doses but had not completed the DTaP series (and had other contributing health factors).

Between 2000–2017, 84% of U.S. pertussis deaths occurred in babies under 2 months old — the window BEFORE they can get their first DTaP.

IF ONLY WE HAD A WAY TO PREVENT THIS....
We do. And yes — we’re upset. These deaths should not be happening.

When children receive the complete 5-dose DTaP series on schedule, the vaccine protects about 98% of them in the year after the final dose. When pregnant women get Tdap between 27–36 weeks, it prevents ~78% of pertussis cases in newborns and is ~91% effective at preventing hospitalization.

The problem is that people aren’t getting it...

DTaP coverage among kindergarteners has fallen to 92.1%, down from about 95% pre-pandemic. That may look like a small drop — until you understand herd immunity thresholds. And until you start counting dead babies.

Pertussis in infants is brutal. About 1 in 3 is hospitalized. About 1 in 5 develops pneumonia. Some suffer seizures or brain swelling. Around 1% die.

Adults describe coughing until they vomit or break ribs.
Infants? They turn blue. They stop breathing. They die.

Whooping cough was rare for decades after vaccination became widespread — until the 2000s, when waning immunity, natural cycles, and pockets of low coverage (fueled by misinformation) allowed it to roar back.

We had this under control. Fear and misinformation are undoing decades of progress.
Get vaccinated. Get your kids vaccinated. If you’re pregnant, get Tdap between 27–36 weeks.

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CDC’s acting director recently claimed that “informed consent is back” for vaccines—implying it ever disappeared. It didn’t. The real concern isn’t a lack of informed consent, but the growing effort to twist it into fear, confusion, and "misinformed refusal".

In this piece, I team up again with incredible colleagues Jessica Steier, DrPH, PMP and Elana Pearl Ben-Joseph, MD, MPH at Unbiased Science explain what informed consent truly is—and what it isn’t—because parents deserve clarity, context, and honesty when making truly informed decisions about their child's health.

#vaccines

https://lnkd.in/gNeaH5Rj