Multiple sclerosis
2.6K views | +0 today
Follow
Your new post is loading...
Your new post is loading...
Scooped by Beeyond
Scoop.it!

Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis

Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis | Multiple sclerosis | Scoop.it

Multiple sclerosis is a chronic demyelinating disease of the central nervous system. The underlying cause of this disease is not known, but Epstein-Barr virus is thought to be a possible culprit. However, most people infected with this common virus do not develop multiple sclerosis, and it is not feasible to directly demonstrate causation of this disease in humans. Using data from millions of US military recruits monitored over a 20-year period, Bjornevik et al. determined that Epstein-Barr virus infection greatly increased the risk of subsequent multiple sclerosis and that it preceded the development of disease, supporting its potential role in the pathogenesis of multiple sclerosis (see the Perspective by Robinson and Steinman). —YN

No comment yet.
Scooped by Beeyond
Scoop.it!

The Gut Microbiome in Multiple Sclerosis: A Potential Therapeutic Avenue

The Gut Microbiome in Multiple Sclerosis: A Potential Therapeutic Avenue | Multiple sclerosis | Scoop.it

The findings suggest that the interactions between the host and the microbiota are reciprocal, although more extensive work is required to confirm this. Moreover, evidence indicates that changes in microbiota composition may result in imbalances that could result in disease, with the gut as a potential novel therapeutic avenue. By understanding the biological effects of aberrant gut microbiome composition, it is possible to contemplate current therapeutic options and their efficacy. Ultimately, more research is necessary in this field, but targeting the gut microbiota may lead to the development of novel therapeutic strategies.

No comment yet.
Scooped by Beeyond
Scoop.it!

Can Myelin Repair Lead to the Reversal of Multiple Sclerosis?

Can Myelin Repair Lead to the Reversal of Multiple Sclerosis? | Multiple sclerosis | Scoop.it

Progress in finding new treatments for neurologic disorders is often slow and incremental, and it rarely yields therapies that inhibit progression of these diseases. Treatment usually focuses on relieving symptoms. An exception to this pattern is treatment for multiple sclerosis (MS). In the late 1980s, researchers began trials on interferon beta-1b, a drug that was shown to modify MS activity. It was approved by the US Food and Drug Administration (FDA) in 1993.

No comment yet.
Scooped by Beeyond
Scoop.it!

How Epstein-Barr virus sets off multiple sclerosis

How Epstein-Barr virus sets off multiple sclerosis | Multiple sclerosis | Scoop.it

New research shows that the Epstein-Barr virus, a common type of herpes virus, triggers multiple sclerosis by priming the immune system to attack the body’s own nervous system.

No comment yet.
Scooped by Beeyond
Scoop.it!

How Epstein-Barr Virus Triggers Multiple Sclerosis

How Epstein-Barr Virus Triggers Multiple Sclerosis | Multiple sclerosis | Scoop.it

Around 25% of patients with multiple sclerosis have blood antibodies that bind to the Epstein-Barr virus and EBNA1, a protein made in the brain and spinal cord. Researchers say this is the first study to definitely show that the Epstein-Barr virus can cause multiple sclerosis in some patients.

No comment yet.
Scooped by Beeyond
Scoop.it!

Des chercheurs identifient le virus à l'origine de la sclérose en plaques

Des chercheurs identifient le virus à l'origine de la sclérose en plaques | Multiple sclerosis | Scoop.it
Cette découverte soulève l'espoir du développement possible d'un futur traitement, qui permettrait de guérir cette maladie affectant environ 2,8 millions de personnes dans le monde.
No comment yet.
Scooped by Beeyond
Scoop.it!

Sclérose en plaques : ce que vous devez savoir

Sclérose en plaques : ce que vous devez savoir | Multiple sclerosis | Scoop.it
Êtes-vous un aidant pour une personne atteinte de sclérose en plaques? Téléchargez ce livret pour des conseils pratiques qui vous aideront à être un partenaire de soins en bonne santé.
No comment yet.
Scooped by Beeyond
Scoop.it!

Hepatitis B Vaccination and the Risk of Multiple Sclerosis

Hepatitis B Vaccination and the Risk of Multiple Sclerosis | Multiple sclerosis | Scoop.it

These results indicate no association between hepatitis B vaccination and the development of multiple sclerosis.

No comment yet.
Scooped by Beeyond
Scoop.it!

Multiple Sclerosis – Icing to reduce spasticity?!

Multiple Sclerosis – Icing to reduce spasticity?! | Multiple sclerosis | Scoop.it

In this video, we will be discussing the use of ice to help reduce spasticity and tightness!

No comment yet.
Scooped by Beeyond
Scoop.it!

Certain ICD-10 Codes Often Precede Multiple Sclerosis Diagnosis

Certain ICD-10 Codes Often Precede Multiple Sclerosis Diagnosis | Multiple sclerosis | Scoop.it

The researchers found that compared with controls without autoimmune disease, 43 ICD-10 codes were recorded more frequently for patients with MS before diagnosis. In comparison to the other control groups, many of these findings were confirmed. A high proportion of these codes represent symptoms indicative of demyelinating events or other neurologic diseases.

No comment yet.
Scooped by Beeyond
Scoop.it!

Newly Diagnosed with MS? Multiple Sclerosis Treatment Options

Newly Diagnosed with MS? Multiple Sclerosis Treatment Options | Multiple sclerosis | Scoop.it

Multiple sclerosis, or MS, is a complex, chronic disease that affects the central nervous system. If you or someone you love has recently been diagnosed with multiple sclerosis, the first step you can take in effectively managing your condition is to learn everything you can about your diagnosis. Ask your provider if he or she has any informational pamphlets about MS, check out organizations like the National MS Society, or read below for a primer on what exactly MS is and how it’s diagnosed.

No comment yet.
Scooped by Beeyond
Scoop.it!

BrainStorm climbs on stem cell data from small multiple sclerosis trial

BrainStorm climbs on stem cell data from small multiple sclerosis trial | Multiple sclerosis | Scoop.it

BrainStorm Cell Therapeutics has presented phase 2 data on its stem cell therapy in patients with multiple sclerosis (MS). The small, open-label clinical trial linked autologous therapy NurOwn to a 25% improvement in measures of mobility and dexterity in around 14% of patients.

No comment yet.
Scooped by Beeyond
Scoop.it!

Stem Cell Transplant May Slow Disability in Multiple Sclerosis

Stem Cell Transplant May Slow Disability in Multiple Sclerosis | Multiple sclerosis | Scoop.it

Long-term outcomes assessed in 210 patients with MS who underwent autologous hematopoietic stem cell transplantation

No comment yet.
Scooped by Beeyond
Scoop.it!

Induction and stability of vaccine-specific antibodies in multiple sclerosis patients on different disease-modifying therapies

Induction and stability of vaccine-specific antibodies in multiple sclerosis patients on different disease-modifying therapies | Multiple sclerosis | Scoop.it

The authors highlight that they have confirmed that the antibody response in the treated patients was significantly lower than in the control groups, in some cases virtually absent, and that this is likely at least partially due to the impaired humoral responses seen in these groups. As well as this, the T cell response to the spike protein is significantly muted in fingolimod-treated patients. The correlation analyses helped show that the length of treatment and reduced capacity to respond to the antibody is likely linked.

No comment yet.
Scooped by Beeyond
Scoop.it!

3 Biotech Leaders In Multiple Sclerosis Innovation

3 Biotech Leaders In Multiple Sclerosis Innovation | Multiple sclerosis | Scoop.it

Multiple sclerosis is one of the most detrimental progressive diseases that doesn’t have a cure. Even if it were to be caught early, the current treatment can only slow the progression of multiple sclerosis by reducing nerve cell inflammation and damage. Basically, multiple sclerosis is where the protective coating of nerves in the spinal cord and the brain gets damaged and destroyed by the body’s own immune system. So it can lead to symptoms such as vision loss, muscle spasms, and impaired coordination. Unfortunately, the cause of this disease is unknown.

No comment yet.
Scooped by Beeyond
Scoop.it!

Treating Multiple Sclerosis with Stem Cell Therapy

Multiple sclerosis (MS) is an autoimmune disease. With these conditions, your immune system mistakenly attacks healthy cells. In people with MS, the immune system attacks cells in the myelin, the protective sheath that surrounds nerves in the brain and spinal cord. Dr. David Greene Arizona is developing stem cell therapies to treat these disorders and many autoimmune diseases.

No comment yet.
Scooped by Beeyond
Scoop.it!

Azurity bags FDA nod for grape-flavored multiple sclerosis drug

Azurity bags FDA nod for grape-flavored multiple sclerosis drug | Multiple sclerosis | Scoop.it

Physicians prescribe baclofen to treat muscle spasms and stiffness in patients with multiple sclerosis and spinal cord injuries. However, the established spinal canal delivery and tablet formulations have certain limitations. Tablets are unsuitable for people who have difficulty swallowing and injections, while getting more of the drug to target sites and addressing some side effects, can be painful.

No comment yet.
Scooped by Beeyond
Scoop.it!

Multiple Sclerosis Assessing mHealth Use Barriers Technological Considerations

Multiple Sclerosis Assessing mHealth Use Barriers Technological Considerations | Multiple sclerosis | Scoop.it

Study findings indicate that people with multiple sclerosis (MS) often experience challenges accessing appropriate healthcare services to address their disease-related needs, including symptom management. One option for improving access to care for patients with MS is to use mobile health (mHealth) technology, defined as the use of mobile and wireless devices to improve health outcomes, healthcare services, and health research.

No comment yet.
Scooped by Beeyond
Scoop.it!

Multiple Sclerosis: Assessing mHealth Use, Barriers, & Technological Considerations

Multiple Sclerosis: Assessing mHealth Use, Barriers, & Technological Considerations | Multiple sclerosis | Scoop.it

Study findings indicate that people with multiple sclerosis (MS) often experience challenges accessing appropriate healthcare services to address their disease-related needs, including symptom management. One option for improving access to care for patients with MS is to use mobile health (mHealth) technology, defined as the use of mobile and wireless devices to improve health outcomes, healthcare services, and health research.

No comment yet.
Scooped by Beeyond
Scoop.it!

Vivre avec une Sclérose en plaques : Paroles d'Aidants

Vivre avec une Sclérose en plaques : Paroles d'Aidants | Multiple sclerosis | Scoop.it

Il suffit parfois d’un soutien pour avancer avec la maladie. Les aidants jouent un rôle essentiel auprès des patients atteints de sclérose en plaques. Ils apportent un soutien moral : ils réconfortent, rassurent, encouragent, apaisent. C’est fréquemment le premier confident du patient. L’aidant intervient aussi souvent dans la vie quotidienne : tâches ménagères, préparation des repas, courses et dossiers administratifs liés à la maladie.

No comment yet.
Scooped by Beeyond
Scoop.it!

The Effect of Self-Acupressure Application on Functional Composite and Quality of Life in Multiple Sclerosis Patients

The Effect of Self-Acupressure Application on Functional Composite and Quality of Life in Multiple Sclerosis Patients | Multiple sclerosis | Scoop.it

Acupressure is a therapy method performed with an instrument or hand, fingertip, palm, elbow, knee, thumb relaxation and wrist bands on various points representing the waist organs in order to ensure the continuation and balance of the energy in our body.

No comment yet.
Scooped by Beeyond
Scoop.it!

Permanent Restrictions After Developing Multiple Sclerosis

Permanent Restrictions After Developing Multiple Sclerosis | Multiple sclerosis | Scoop.it

Multiple sclerosis (MS) sufferers may develop a disabling condition severe enough to prevent them from continuing in employment or returning to work after a relapse. If as a MS sufferer you face permanent restrictions on being able to work you may be eligible for a social security disability benefit from the Social Security Administration (SSA).

No comment yet.
Scooped by Beeyond
Scoop.it!

Patient-reported financial toxicity in multiple sclerosis: Predictors and association with care non-adherence

Patient-reported financial toxicity in multiple sclerosis: Predictors and association with care non-adherence | Multiple sclerosis | Scoop.it

Multiple sclerosis (MS) results in considerable financial burdens due to expensive treatment and high rates of disability, which could both impact care non-adherence.

MS patients with lower financial self-efficacy and prior relapse history are at higher risk for financial toxicity, with associated care non-adherence and lower HRQOL.

No comment yet.
Scooped by Beeyond
Scoop.it!

What Is Multiple Sclerosis?

What Is Multiple Sclerosis? | Multiple sclerosis | Scoop.it

Multiple sclerosis (MS) is an autoimmune disease in which the body's immune system attacks its own central nervous system (the brain and spinal cord). In MS, the immune system attacks and damages or destroys myelin, a substance that surrounds and insulates the nerves. The myelin destruction causes a distortion or interruption in nerve impulses traveling to and from the brain. This can result in a wide variety of symptoms.

No comment yet.
Scooped by Beeyond
Scoop.it!

Immune Cells Silence Neurons by Removing Synapses in Multiple Sclerosis

Immune Cells Silence Neurons by Removing Synapses in Multiple Sclerosis | Multiple sclerosis | Scoop.it

Damage to the brain gray matter plays an important role in the progression of multiple sclerosis. This study now shows that such damage can be caused by inflammatory reactions that lead to loss of synapses, which impairs neural activity.

No comment yet.